Cited by 1,249Gastrointestinal motility and disordersGut microbiota and healthInfant Health and Development

A Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome

Halmos, Emma P., Power, Victoria A., Shepherd, Susan J., Gibson, Peter R., Muir, Jane G.·2014·Gastroenterology

Abstract

Background & aims A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) often is used to manage functional gastrointestinal symptoms in patients with irritable bowel syndrome (IBS), yet there is limited evidence of its efficacy, compared with a normal Western diet. We investigated the effects of a diet low in FODMAPs compared with an Australian diet, in a randomized, controlled, single-blind, cross-over trial of patients with IBS. Methods In a study of 30 patients with IBS and 8 healthy individuals (controls, matched for demographics and diet), we collected dietary data from subjects for 1 habitual week. Participants then randomly were assigned to groups that received 21 days of either a diet low in FODMAPs or a typical Australian diet, followed by a washout period of at least 21 days, before crossing over to the alternate diet. Daily symptoms were rated using a 0- to 100-mm visual analogue scale. Almost all food was provided during the interventional diet periods, with a goal of less than 0.5 g intake of FODMAPs per meal for the low-FODMAP diet. All stools were collected from days 17-21 and assessed for frequency, weight, water content, and King's Stool Chart rating. Results Subjects with IBS had lower overall gastrointestinal symptom scores (22.8; 95% confidence interval, 16.7-28.8 mm) while on a diet low in FODMAPs, compared with the Australian diet (44.9; 95% confidence interval, 36.6-53.1 mm; P Conclusions In a controlled, cros…

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Crossref · 10.1053/j.gastro.2013.09.046

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Authors
Halmos, E. P., Power, V. A., Shepherd, S. J., Gibson, P. R., & Muir, J. G.
Affiliations
Eastern Health (AU)
Corresponding author
Halmos, Emma P.
Venue
Gastroenterology
Publisher
Elsevier BV
Published
2014-01
Volume
146
Issue
1
Pages
67-75.e5
ISSN
0016-5085 (ISSN-L)
OpenAlex
W2028507955
Cited by
1,249
References
32
Citations by year
2026: 54 · 2025: 76 · 2024: 65 · 2023: 70 · 2022: 105 · 2021: 120 · 2020: 102 · 2019: 103 · 2018: 104 · 2017: 146 · 2016: 130 · 2015: 108 · 2014: 59 · 2013: 4 · 2012: 1
FWCI
94.63
Type
journal article
Language
en
Open access
closed
Locations
  • Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Health and Medical Research Council
  • Faculty of Medicine, Nursing and Health Sciences, Monash University
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Health Professions › Pharmacy › Infant Health and Development
Keywords
irritable bowel syndrome, low FODMAP diet, FODMAPs, functional gastrointestinal symptoms, bloating, abdominal pain, stool consistency, diarrhea-predominant irritable bowel syndrome, Western diet, dietary intervention, dietary adherence, IBS subtypes
MeSH terms
Adult, Disaccharides, Female, Fermentation, Humans, Male, Middle Aged, Monosaccharides, Oligosaccharides, Sugar Alcohols, Case-Control Studies, Single-Blind Method, Treatment Outcome, Cross-Over Studies, Irritable Bowel Syndrome, Young Adult

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