The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.
Harnessing the beneficial heterologous effects of vaccination
Open accessAbstract
Clinical evidence strongly suggests that certain live vaccines, in particular bacille Calmette–Guérin (BCG) and measles vaccines, can reduce all-cause mortality, most probably through protection against non-targeted pathogens in addition to the targeted pathogen. The underlying mechanisms are currently unknown. We discuss how heterologous lymphocyte activation and innate immune memory could promote protection beyond the intended target pathogen and consider how vaccinologists could leverage heterologous immunity to improve outcomes in vulnerable populations, in particular the very young and the elderly.
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Cites
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
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Self-citationVaccine Adjuvants: Putting Innate Immunity to Work
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Self-citationEpigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
Saeed, S., Quintin, J., Kerstens, H. H. D., Rao, N. A., Aghajanirefah, A., Matarese, F., Cheng, S.-C., Ratter, J., Berentsen, K., van der Ent, M. A., et al. (2014) · Science · doi:10.1126/science.1251086 · Cited by 1,761
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Self-citationTrained Immunity: A Memory for Innate Host Defense
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Self-citationAdaptive immune features of natural killer cells
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Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
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Self-citationYáñez, A., Coetzee, S. G., Olsson, A., Muench, D. E., Berman, B. P., Hazelett, D. J., Salomonis, N., Grimes, H. L., & Goodridge, H. S. (2017) · Immunity · doi:10.1016/j.immuni.2017.10.021 · Cited by 470
Self-citationNon-specific effects of BCG vaccine on viral infections
Moorlag, S. J. C. F. M., Arts, R. J. W., van Crevel, R., & Netea, M. G. (2019) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2019.04.020 · Cited by 479
Self-citationProtecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny
Kollmann, T. R., Kampmann, B., Mazmanian, S. K., Marchant, A., & Levy, O. (2017) · Immunity · doi:10.1016/j.immuni.2017.03.009 · Cited by 478
Self-citationMeasles virus infection diminishes preexisting antibodies that offer protection from other pathogens
Mina, M. J., Kula, T., Leng, Y., Li, M., de Vries, R. D., Knip, M., Siljander, H., Rewers, M., Choy, D. F., Wilson, M. S., et al. (2019) · Science · doi:10.1126/science.aay6485 · Cited by 466
Metadata
- Authors
- Goodridge, H. S., Ahmed, S. S., Curtis, N., Kollmann, T. R., Levy, O., Netea, M. G., Pollard, A. J., van Crevel, R., & Wilson, C. B.
- Venue
- Nature Reviews Immunology
- Published
- 2016-05-09
- Volume
- 16
- Issue
- 6
- Pages
- 392-400
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2345654247
- Cited by
- 258
- References
- 104
- FWCI
- 1.76
- Type
- journal article
- Language
- en
- Open access
- green
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- Goodridge, H. S., Ahmed, S. S., Curtis, N., Kollmann, T. R., Levy, O., Netea, M. G., Pollard, A. J., van Crevel, R., & Wilson, C. B. (2016). Harnessing the beneficial heterologous effects of vaccination. Nature Reviews Immunology. https://doi.org/10.1038/nri.2016.43
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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