The DOI matches its Crossref record; 110 of the 110 references it cites were found in a registry or an index.
Immunological implications of pregnancy-induced microchimerism
Open accessAbstract
Immunological identity is traditionally defined by genetically encoded antigens, with equal maternal and paternal contributions as a result of Mendelian inheritance. However, vertically transferred maternal cells also persist in individuals at very low levels throughout postnatal development. Reciprocally, mothers are seeded during pregnancy with genetically foreign fetal cells that persist long after parturition. Recent findings suggest that these microchimeric cells expressing non-inherited, familially relevant antigenic traits are not accidental 'souvenirs' of pregnancy, but are purposefully retained within mothers and their offspring to promote genetic fitness by improving the outcome of future pregnancies. In this Review, we discuss the immunological implications, benefits and potential consequences of individuals being constitutively chimeric with a biologically active 'microchiome' of genetically foreign cells.
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Cites
The Physiology of Reproduction
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,861
Sex differences in immune responses
Klein, S. L., & Flanagan, K. L. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.90 · Cited by 6,370
Gut microbiota, metabolites and host immunity
Rooks, M. G., & Garrett, W. S. (2016) · Nature reviews. Immunology · doi:10.1038/nri.2016.42 · Cited by 3,409
Maeda, K.-I., Ohkura, S., & Tsukamura, H. (2000) · The Laboratory Rat · doi:10.1016/b978-012426400-7.50048-0 · Cited by 2,127
Regulatory T cells mediate maternal tolerance to the fetus
Aluvihare, V. R., Kallikourdis, M., & Betz, A. G. (2004) · Nature Immunology · doi:10.1038/ni1037 · Cited by 1,657
Reciprocal interactions of the intestinal microbiota and immune system
Maynard, C. L., Elson, C. O., Hatton, R. D., & Weaver, C. T. (2012) · Nature · doi:10.1038/nature11551 · Cited by 1,598
Rate of Pregnancy-Related Relapse in Multiple Sclerosis
Confavreux, C., Hutchinson, M., Hours, M. M., Cortinovis-Tourniaire, P., & Moreau, T. (1998) · New England Journal of Medicine · doi:10.1056/nejm199807303390501 · Cited by 1,559
Immunogenetic Consequences of Vascular Anastomoses Between Bovine Twins
Owen, R. D. (1945) · Science · doi:10.1126/science.102.2651.400 · Cited by 1,368
Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum
Bianchi, D. W., Zickwolf, G. K., Weil, G. J., Sylvester, S., & DeMaria, M. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.2.705 · Cited by 1,264
Immunology of the Maternal-Fetal Interface
Erlebacher, A. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-100003 · Cited by 982
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Uncovering sex differences of rodent microglia
Han, J., Fan, Y., Zhou, K., Blomgren, K., & Harris, R. A. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02124-z · Cited by 224
The immunobiology of female predominance in primary biliary cholangitis
Gerussi, A., Cristoferi, L., Carbone, M., Asselta, R., & Invernizzi, P. (2018) · Journal of Autoimmunity · doi:10.1016/j.jaut.2018.10.015 · Cited by 41
Metadata
- Authors
- Kinder, J. M., Stelzer, I. A., Arck, P. C., & Way, S. S.
- Venue
- Nature Reviews Immunology
- Published
- 2017-05-08
- Volume
- 17
- Issue
- 8
- Pages
- 483-494
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2613142622
- Cited by
- 266
- References
- 110
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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