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Cited by 805

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Immune surveillance in the skin: mechanisms and clinical consequences

Open access
Kupper, Thomas S., Fuhlbrigge, Robert C.·2004·Nature Reviews Immunology

Abstract

The skin, as the primary interface between the body and the environment, provides the first line of defence against a broad array of microbial pathogens and trauma. In addition to its properties as a physical barrier, the skin has many active defence mechanisms. In this review, we discuss the interaction between the innate and adaptive immune systems in the skin as a model for immune function at epithelial-cell interfaces with the environment. How these mechanisms account for the robust nature of cutaneous immune surveillance and how their dysregulation drives the pathogenesis of inflammatory skin disorders and skin-based tumours are the subjects of this review.

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Crossref · 10.1038/nri1310

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Metadata

Authors
Kupper, T. S., & Fuhlbrigge, R. C.
Venue
Nature Reviews Immunology
Published
2004-03-01
Volume
4
Issue
3
Pages
211-222
ISSN
  • 1474-1733 (ISSN-L)
  • 1474-1741
OpenAlex
W2006120701
Cited by
805
References
7
FWCI
9.59
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Immune surveillance in the skin: mechanisms and clinical consequences. https://app.cochat.ai/papers/10.1038/nri1310
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Kupper, T. S., & Fuhlbrigge, R. C. (2004). Immune surveillance in the skin: mechanisms and clinical consequences. Nature Reviews Immunology. https://doi.org/10.1038/nri1310

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.