The DOI matches its Crossref record; 145 of the 145 references it cites were found in a registry or an index.
The role of ubiquitylation in immune defence and pathogen evasion
Open accessAbstract
Ubiquitylation is a widely used post-translational protein modification that regulates many biological processes, including immune responses. The role of ubiquitin in immune regulation was originally uncovered through studies of antigen presentation and the nuclear factor-κB family of transcription factors, which orchestrate host defence against microorganisms. Recent studies have revealed crucial roles of ubiquitylation in many aspects of the immune system, including innate and adaptive immunity and antimicrobial autophagy. In addition, mounting evidence indicates that microbial pathogens exploit the ubiquitin pathway to evade the host immune system. Here, we review recent advances on the role of ubiquitylation in host defence and pathogen evasion.
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Cites
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Self-citationMechanisms Underlying Ubiquitination
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Self-citation
Cited by
Deubiquitylating enzymes and drug discovery: emerging opportunities
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Association of host genome with intestinal microbial composition in a large healthy cohort
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Dissecting negative regulation of Toll-like receptor signaling
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Metadata
- Authors
- Jiang, X., & Chen, Z. J.
- Venue
- Nature Reviews Immunology
- Published
- 2011-12-09
- Volume
- 12
- Issue
- 1
- Pages
- 35-48
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2144704426
- Cited by
- 353
- References
- 145
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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