The DOI matches its Crossref record; 164 of the 164 references it cites were found in a registry or an index.
Expanding roles for CD4+ T cells in immunity to viruses
Open accessAbstract
Viral pathogens often induce strong effector CD4+ T cell responses that are best known for their ability to help B cell and CD8+ T cell responses. However, recent studies have uncovered additional roles for CD4+ T cells, some of which are independent of other lymphocytes, and have described previously unappreciated functions for memory CD4+ T cells in immunity to viruses. Here, we review the full range of antiviral functions of CD4+ T cells, discussing the activities of these cells in helping other lymphocytes and in inducing innate immune responses, as well as their direct antiviral roles. We suggest that all of these functions of CD4+ T cells are integrated to provide highly effective immune protection against viral pathogens.
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Cites
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Systemic Immunity Is Required for Effective Cancer Immunotherapy
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Metadata
- Authors
- Swain, S. L., McKinstry, K. K., & Strutt, T. M.
- Venue
- Nature Reviews Immunology
- Published
- 2012-01-20
- Volume
- 12
- Issue
- 2
- Pages
- 136-148
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2024524568
- Cited by
- 956
- References
- 164
- FWCI
- 2.86
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
