The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Advances in graft-versus-host disease biology and therapy
Open accessAbstract
Allogeneic haematopoietic stem cell transplantation is used to treat a variety of disorders, but its efficacy is limited by the occurrence of graft-versus-host disease (GVHD). The past decade has brought impressive advances in our understanding of the role of stimulatory and suppressive elements of the adaptive and innate immune systems from both the donor and the host in GVHD pathogenesis. New insights from basic immunology, preclinical models and clinical studies have led to novel approaches for prevention and treatment. This Review highlights the recent advances in understanding the pathophysiology of GVHD and its treatment, with a focus on manipulations of the immune system that are amenable to clinical application.
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Regulation of the mevalonate pathway
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Human mesenchymal stem cells modulate allogeneic immune cell responses
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Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
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Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
Di Stasi, A., Tey, S.-K., Dotti, G., Fujita, Y., Kennedy-Nasser, A., Martinez, C., Straathof, K., Liu, E., Durett, A. G., Grilley, B., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1106152 · Cited by 1,512
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
Nurieva, R., Yang, X. O., Martinez, G., Zhang, Y., Panopoulos, A. D., Ma, L., Schluns, K., Tian, Q., Watowich, S. S., Jetten, A. M., et al. (2007) · Nature · doi:10.1038/nature05969 · Cited by 1,466
Probiotic effects on experimental graft-versus-host disease: let them eat yogurt
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Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients
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Cited by
Shono, Y., Docampo, M. D., Peled, J. U., Perobelli, S. M., Velardi, E., Tsai, J. J., Slingerland, A. E., Smith, O. M., Young, L. F., Gupta, J., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf2311 · Cited by 592
Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease
Zeiser, R., Polverelli, N., Ram, R., Hashmi, S. K., Chakraverty, R., Middeke, J. M., Musso, M., Giebel, S., Uzay, A., Langmuir, P., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2033122 · Cited by 527
Cooke, K. R., Luznik, L., Sarantopoulos, S., Hakim, F. T., Jagasia, M., Fowler, D. H., van den Brink, M. R. M., Hansen, J. A., Parkman, R., Miklos, D. B., et al. (2017) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2016.09.023 · Cited by 472
Self-citationImmune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation
Ogonek, J., Kralj Juric, M., Ghimire, S., Varanasi, P. R., Holler, E., Greinix, H., & Weissinger, E. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00507 · Cited by 458
Homeostatic control of regulatory T cell diversity
Liston, A., & Gray, D. H. D. (2014) · Nature Reviews Immunology · doi:10.1038/nri3605 · Cited by 427
Metadata
- Authors
- Blazar, B. R., Murphy, W. J., & Abedi, M.
- Venue
- Nature Reviews Immunology
- Published
- 2012-05-11
- Volume
- 12
- Issue
- 6
- Pages
- 443-458
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2017467835
- Cited by
- 880
- References
- 10
- FWCI
- 9.42
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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