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Cited by 458

The DOI matches its Crossref record; 130 of the 130 references it cites were found in a registry or an index.

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation

Open access
Ogonek, Justyna, Kralj Juric, Mateja, Ghimire, Sakhila, Varanasi, Pavankumar Reddy, Holler, Ernst, Greinix, Hildegard, Weissinger, Eva·2016·Frontiers in Immunology

Abstract

The timely reconstitution and regain of function of a donor-derived immune system is of utmost importance for the recovery and long-term survival of patients after allogeneic hematopoietic stem cell transplantation (HSCT). Of note, new developments such as umbilical cord blood or haploidentical grafts were associated with prolonged immunodeficiency due to delayed immune reconstitution, raising the need for better understanding and enhancing the process of immune reconstitution and finding strategies to further optimize these transplant procedures. Immune reconstitution post-HSCT occurs in several phases, innate immunity being the first to regain function. The slow T cell reconstitution is regarded as primarily responsible for deleterious infections with latent viruses or fungi, occurrence of graft-versus-host disease, and relapse. Here we aim to summarize the major steps of the adaptive immune reconstitution and will discuss the importance of immune balance in patients after HSCT.

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Metadata

Authors
Ogonek, J., Kralj Juric, M., Ghimire, S., Varanasi, P. R., Holler, E., Greinix, H., & Weissinger, E.
Venue
Frontiers in Immunology
Published
2016-11-17
Volume
7
Pages
507-507
ISSN
1664-3224 (ISSN-L)
OpenAlex
W2553604175
Cited by
458
References
130
FWCI
20.28
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation. https://app.cochat.ai/papers/10.3389/fimmu.2016.00507
The paper
Ogonek, J., Kralj Juric, M., Ghimire, S., Varanasi, P. R., Holler, E., Greinix, H., & Weissinger, E. (2016). Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2016.00507

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