The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Epithelial antimicrobial defence of the skin and intestine
Open accessAbstract
Surface tissues of the body such as the skin and intestinal tract are in direct contact with the external environment and are thus continuously exposed to large numbers of microorganisms. To cope with the substantial microbial exposure, epithelial surfaces produce a diverse arsenal of antimicrobial proteins that directly kill or inhibit the growth of microorganisms. In this Review, we highlight new advances in our understanding of how epithelial antimicrobial proteins protect against pathogens and contribute to microbiota–host homeostasis at the skin and gut mucosae. Further, we discuss recent insights into the regulatory mechanisms that control antimicrobial protein expression. Finally, we consider how impaired antimicrobial protein expression and function can contribute to disease.
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Citations
Cites
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Self-citationEndogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis
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Self-citationPlasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
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Cited by
The gut microbiota--masters of host development and physiology
Sommer, F., & Bäckhed, F. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2974 · Cited by 3,681
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Gut biogeography of the bacterial microbiota
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The gut-liver axis and the intersection with the microbiome
Tripathi, A., Debelius, J., Brenner, D. A., Karin, M., Loomba, R., Schnabl, B., & Knight, R. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0011-z · Cited by 1,480
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Self-citation
Metadata
- Authors
- Gallo, R. L., & Hooper, L. V.
- Venue
- Nature Reviews Immunology
- Published
- 2012-06-25
- Volume
- 12
- Issue
- 7
- Pages
- 503-516
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2077590888
- Cited by
- 957
- References
- 28
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- green
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