The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Chemokine receptors: multifaceted therapeutic targets
Open accessAbstract
Chemokines and their receptors are involved in the pathogenesis of diseases ranging from asthma to AIDS. Chemokine receptors are G-protein-coupled serpentine receptors that present attractive tractable targets for the pharmaceutical industry. It is only ten years since the first chemokine receptor was discovered, and the rapidly expanding number of antagonists holds promise for new medicines to combat diseases that are currently incurable. Here, I focus on the rationale for developing antagonists of chemokine receptors for inflammatory disorders and AIDS, and the accumulating evidence that favours this strategy despite the apparent redundancy in the chemokine system.
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Cites
Boring, L., Gosling, J., Cleary, M., & Charo, I. F. (1998) · Nature · doi:10.1038/29788 · Cited by 1,965
Acute axonal injury in multiple sclerosis: Correlation with demyelination and inflammation
Bitsch, A. (2000) · Brain · doi:10.1093/brain/123.6.1174 · Cited by 898
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Metadata
- Authors
- Proudfoot, A. E. I.
- Venue
- Nature Reviews Immunology
- Published
- 2002-02-01
- Volume
- 2
- Issue
- 2
- Pages
- 106-115
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2019879894
- Cited by
- 752
- References
- 2
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
