Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation

Dominguez, Antonia A., Lim, Wendell A., Qi, Lei S.·2016·Nature Reviews Molecular Cell Biology

Cited by (834)

Items 301–400 of 834

  1. CRISPR applications in cancer diagnosis and treatment
    Mingxia Wang, Menghui Chen, Xia Wu, Xinbo Huang, Bo Yu · 2023 · Cellular & Molecular Biology Letters
  2. Advancements in CRISPR/Cas systems for disease treatment
    Yangsong Xu, Hao Le, Qinjie Wu, Ning Wang, Changyang Gong · 2025 · Acta Pharmaceutica Sinica B
  3. Gene delivery to the lungs: pulmonary gene therapy for cystic fibrosis
    Ilia Villate-Beitia, Jon Zárate Sesma, Gustavo Puras, José Luís Pedraz · 2017 · Drug Development and Industrial Pharmacy
  4. Enhancing Protein Production Yield from Chinese Hamster Ovary Cells by CRISPR Interference
    Chih‐Che Shen, Li‐Yu Sung, Shih-Yeh Lin, Mei‐Wei Lin, Yu‐Chen Hu · 2017 · ACS Synthetic Biology
  5. Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families
    Ana Iochabel Soares Moretti, Jéssyca Cristine Pavanelli, Patrícia Nolasco, Matthias S. Leisegang, Leonardo Y. Tanaka, Carolina Gonçalves Fernandes, João Wosniak, Daniela Kajihara, Matheus Henrique Dias, Denise C. Fernandes et al. · 2017 · Scientific Reports
  6. Applications of CRISPR/Cas9 in the Mammalian Central Nervous System.
    Katherine E. Savell, Jeremy J. Day · 2017 · PubMed Central
  7. Building Endogenous Gene Connections through RNA Self-Assembly Controlled CRISPR/Cas9 Function
    Jiao Lin, Weijia Wang, Yang Wang, Yan Liu, Liang Xu · 2021 · Journal of the American Chemical Society
  8. CRISPR-Mediated Synergistic Epigenetic and Transcriptional Control
    Antonia A. Dominguez, Michael Chavez, Amanda Urke, Yuchen Gao, Lizhong Wang, Lei S. Qi · 2022 · The CRISPR Journal
  9. CRISPR Technologies in Chinese Hamster Ovary Cell Line Engineering
    Katja Glinšek, Krištof Bozovičar, Tomaž Bratkovič · 2023 · International Journal of Molecular Sciences
  10. Genome Editing for Cystic Fibrosis
    Guoshun Wang · 2023 · Cells
  11. CRISPR/Cas9: a powerful tool in colorectal cancer research
    Yang Hu, Liang Liu, Qi Jiang, Weiping Fang, Yazhu Chen, Yuntian Hong, Xiang Zhai · 2023 · Journal of Experimental & Clinical Cancer Research
  12. Foxp3 promoter methylation impairs suppressive function of regulatory T cells in biliary atresia
    Kang Li, Xi Zhang, Li Yang, Xinxing Wang, Dehua Yang, Guoqing Cao, Shuai Li, Yong-zhong Mao, Shao‐tao Tang · 2016 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  13. Genetic switches designed for eukaryotic cells and controlled by serine integrases
    Mayna da Silveira Gomide, Thais Torquato Sales, Luciana Rodrigues Carvalho Barros, Cintia Elisabeth Gomez Limia, Marco A. de Oliveira, Lílian H. Florentino, L. M. G. Barros, Maria L. Robledo, G. Pinheiro Coelho José, Mariana S. M. Almeida et al. · 2020 · Communications Biology
  14. CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator ofIGF2imprinting in tumors
    Yi Qun Zhang, Ji‐Fan Hu, Hong Wang, Jiuwei Cui, Sujun Gao, Andrew R. Hoffman, Wei Li · 2016 · Oncotarget
  15. Efficient and Heritable Targeted Mutagenesis in Mosses Using the CRISPR/Cas9 System
    Toshihisa Nomura, Tetsuya Sakurai, Yuriko Osakabe, Keishi Osakabe, Hitoshi Sakakibara · 2016 · Plant and Cell Physiology
  16. Inducible CRISPR genome-editing tool: classifications and future trends
    Xiaofeng Dai, Xiao Chen, Qiuwu Fang, Jia Li, Zhonghu Bai · 2017 · Critical Reviews in Biotechnology
  17. Gene activation by a CRISPR-assisted trans enhancer
    Xinhui Xu, Jinliang Gao, Wei Dai, Danyang Wang, Jian Wu, Jinke Wang · 2019 · eLife
  18. Delivery of Cas13a/crRNA by self-degradable black phosphorus nanosheets to specifically inhibit Mcl-1 for breast cancer therapy
    Huahua Yue, Ru Qiang Huang, Yuanyue Shan, Da Xing · 2020 · Journal of Materials Chemistry B
  19. The Function of KDEL Receptors as UPR Genes in Disease
    Emily S. Wires, Kathleen A. Trychta, Lacey M. Kennedy, Brandon K. Harvey · 2021 · International Journal of Molecular Sciences
  20. Nanotechnology‐based CRISPR/Cas9 delivery system for genome editing in cancer treatment
    Shiyao Zhou, Yingjie Li, Qinjie Wu, Changyang Gong · 2024 · MedComm – Biomaterials and Applications
  21. Multidimensional Control of Cas9 by Evolved RNA Polymerase-Based Biosensors
    Jinyue Pu, Kaitlin Kentala, Bryan C. Dickinson · 2017 · ACS Chemical Biology
  22. Genetic engineering of host organisms for pharmaceutical synthesis
    Joseph H Collins, Eric M. Young · 2018 · Current Opinion in Biotechnology
  23. A Drosophila CRISPR/Cas9 Toolkit for Conditionally Manipulating Gene Expression in the Prothoracic Gland as a Test Case for Polytene Tissues
    Nhan Huynh, Jie Zeng, Wen Liu, Kirst King‐Jones · 2018 · G3 Genes Genomes Genetics
  24. Medical applications of clustered regularly interspaced short palindromic repeats (CRISPR/Cas) tool: A comprehensive overview
    Rodrigo Pinheiro Araldi, Charbel Khalil, Pedro Henrique Grignet, Michelli Ramires Teixeira, Thatiana Corrêa de Melo, Diego Grando Módolo, Luis G. V. Fernandes, Jorge Luis María Ruiz, Edislane Barreiros de Souza · 2020 · Gene
  25. Toward a translationally independent RNA-based synthetic oscillator using deactivated CRISPR-Cas
    James Kuo, Ruoshi Yuan, Carlos Martínez Sánchez, Johan Paulsson, Pamela A. Silver · 2020 · Nucleic Acids Research
  26. Stable expression of large transgenes via the knock-in of an integrase-deficient lentivirus
    Michael Chavez, Draven A. Rane, Xinyi Chen, Lei S. Qi · 2023 · Nature Biomedical Engineering
  27. Combinatorial pathway engineering using type I‐E CRISPR interference
    Katia Tarasava, Rongming Liu, Andrew D. Garst, Ryan T. Gill · 2018 · Biotechnology and Bioengineering
  28. Revisiting CRISPR/Cas-mediated crop improvement: special focus on nutrition
    Kaul, Tanushri, Sony, Sonia Khan, Verma, Rachana, Motelb, Khaled Fathy Abdel, Prakash, Arul T, Eswaran, Murugesh, Bharti, Jyotsna, Nehra, Mamta, Kaul, Rashmi · 2020 · Journal of Biosciences
  29. Transgenerationally Transmitted DNA Demethylation of a Spontaneous Epialleles Using CRISPR/dCas9-TET1cd Targeted Epigenetic Editing in Arabidopsis
    Min Wang, Li Sheng He, Bowei Chen, Yanwei Wang, Lishan Wang, Wei Jun Zhou, Tianxu Zhang, Lesheng Cao, Peng Zhang, Linan Xie et al. · 2022 · International Journal of Molecular Sciences
  30. Emerging technology has a brilliant future: the CRISPR-Cas system for senescence, inflammation, and cartilage repair in osteoarthritis
    Shicheng Jia, Rongji Liang, Jiayou Chen, Shuai Liao, Jianjing Lin, Wei Li · 2024 · Cellular & Molecular Biology Letters
  31. Harnessing noncanonical crRNA for highly efficient genome editing
    Guanhua Xun, Zhixin Zhu, Nilmani Singh, Jingxia Lu, Piyush Jain, Huimin Zhao · 2024 · Nature Communications
  32. Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
    Khaled S. Allemailem, Ahmad Almatroudi, Arshad Husain Rahmani, Faris Alrumaihi, Arwa Essa Alradhi, Amal Al-Subaiyel, Mohammad Algahtani, Rand Mohammad Almousa, Ali Mahzari, Abdulmajeed Abdulghani A. Sindi et al. · 2024 · International Journal of Nanomedicine
  33. Recent Advances and Prospects of Nucleic Acid Therapeutics for Anti-Cancer Therapy
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  34. On Improving CRISPR for Editing Plant Genes: Ribozyme-Mediated Guide RNA Production and Fluorescence-Based Technology for Isolating Transgene-Free Mutants Generated by CRISPR
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  35. Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans
    Nicholas C Gervais, Alyssa Ann La Bella, Lauren F. Wensing, Jehoshua Sharma, Victoria Acquaviva, Madison A. Best, Ricardo Omar Cadena López, Meea Fogal, Deeva Uthayakumar, Alejandro Chavez et al. · 2022 · G3 Genes Genomes Genetics
  36. Therapeutic strategies for autism: targeting three levels of the central dogma of molecular biology
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  37. Integrated epigenetic and genetic programming of primary human T cells
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  38. Leading approaches in synthetic epigenetics for novel therapeutic strategies
    Kenzo Yamatsugu, Shigehiro A. Kawashima, Motomu Kanai · 2018 · Current Opinion in Chemical Biology
  39. The evolution and history of gene editing technologies
    Shubhchintan Randhawa, Shatakshi Sengar · 2021 · Progress in molecular biology and translational science
  40. Transcriptional regulation by CRISPR/dCas9 in common wheat
    Huajie Zhou, Lei Xu, Feng Li, Yansha Li · 2021 · Gene
  41. Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons
    Jason P. Chua, Karan Bedi, Michelle T. Paulsen, Mats E. Ljungman, Elizabeth M.H. Tank, Erin S. Kim, Jonathon P. McBride, J Colon, Michael Emmerson Ward, Lois S. Weisman et al. · 2022 · Current Biology
  42. BAPC-assisted CRISPR/Cas9 System: Targeted Delivery into Adult Ovaries for Heritable Germline Gene Editing (Arthropoda: Hemiptera)
    Wayne Brian Hunter, Maria T. Gonzalez, John M. Tomich · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Myogenic potential of mesenchymal stem cells isolated from porcine adipose tissue
    Derek J. Milner, Massimo Bionaz, Elisa Lo Monaco, Jo Ann Cameron, Matthew B. Wheeler · 2018 · Cell and Tissue Research
  44. Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells
    Xi Wang, Chengfu Yuan, Bo Huang, Jiaming Fan, Yixiao Feng, Alexander J. Li, Bo Zhang, Lei Yan, Zhenyu Ye, Ling Zhao et al. · 2019 · ACS Synthetic Biology
  45. Epigenetic Histone Modifications in the Pathogenesis of Diabetic Kidney Disease
    Hengcheng Lu, Wenni Dai, Liyu He · 2021 · Diabetes Metabolic Syndrome and Obesity
  46. Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice
    Charleen Hunt, Suzanne A. Hartford, Derek White, Evangelos Pefanis, Timothy Hanna, Clarissa Herman, Jarrell Wiley, Heather M. Brown, Qi Su, Yurong Xin et al. · 2021 · Nature Communications
  47. Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems
    Sergey Brezgin, Anastasiya Kostyusheva, Баюрова Екатерина Олеговна, Elena V. Volchkova, Vladimir Gegechkori, Ilya V. Gordeychuk, Dieter Glebe, Dmitry S. Kostyushev, Vladimir Chulanov · 2021 · Viruses
  48. The African turquoise killifish (Nothobranchius furzeri): biology and research applications
    Gwendoline Astre, Eitan Moses, Itamar Harel · 2021 · Elsevier eBooks
  49. The CRISPR technology: A promising strategy for improving dark fermentative biohydrogen production using Clostridium spp.
    Cut Ulfah Nihayati Husaini, Rozieffa Roslan, Ahmad Bazli Ramzi, Abdullah Amru Indera Luthfi, Jian Ping Tan, Swee Su Lim, Gongtao Ding, Jamaliah Md Jahim, Peer Mohamed Abdul · 2023 · International Journal of Hydrogen Energy
  50. HIT-Cas9: A CRISPR/Cas9 Genome-Editing Device under Tight and Effective Drug Control
    Chen Zhao, Yingze Zhao, Jingfang Zhang, Jia Q. Lu, Li Chen, Yue Zhang, Ying Yue, Junjun Xu, Shixian Wei, Yu Wang · 2018 · Molecular Therapy — Nucleic Acids
  51. CRISPR interference (CRISPRi) as transcriptional repression tool for Hungateiclostridium thermocellum DSM 1313
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  52. Direct-seq: programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screen
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  53. Applications of CRISPR-Cas for synthetic biology and genetic recording
    Florian Schmidt, Randall J. Platt · 2017 · Current Opinion in Systems Biology
  54. The evolution of CRISPR/Cas9 and their cousins: hope or hype?
    Kul Bhushan, Anirudha Chattopadhyay, Dharmendra Pratap · 2018 · Biotechnology Letters
  55. Lipopeptide‐Based Nanosome‐Mediated Delivery of Hyperaccurate CRISPR/Cas9 Ribonucleoprotein for Gene Editing
    Trung Thanh Thach, Do Hyun Bae, Nam Hyeong Kim, Eun Sung Kang, Bok Soo Lee, Kayoung Han, Minsuk Kwak, Hojae Choi, Jiyoung Nam, Taegeun Bae et al. · 2019 · Small
  56. A New‐Generation Base Editor with an Expanded Editing Window for Microbial Cell Evolution In Vivo Based on CRISPR‒Cas12b Engineering
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  57. Synthetic biology: insights into biological computation
    Romilde Manzoni, Arturo Urrios, Silvia Velázquez-García, Eulàlia de Nadal, Francesc Posas · 2016 · Integrative Biology
  58. An all-in-one UniSam vector system for efficient gene activation
    A Fidanza, Martha Lopez‐Yrigoyen, Nicola Romanò, Rhiannon Jones, A. Helen Taylor, Lesley M. Forrester · 2017 · Scientific Reports
  59. CRISPR-mediated activation of endogenous BST-2/tetherin expression inhibits wild-type HIV-1 production
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  60. Building a genome engineering toolbox in nonmodel prokaryotic microbes
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  61. CRISPR/Cas9 Mutagenesis and Expression of Dominant Mutant Transgenes as Functional Genomic Approaches in Parasitic Nematodes
    James B. Lok · 2019 · Frontiers in Genetics
  62. Evolving targets for anti-epileptic drug discovery
    Dezaree Raut, Lokesh Kumar Bhatt · 2020 · European Journal of Pharmacology
  63. Targeting non-coding RNAs for the treatment of retinal diseases
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  64. Active Delivery of CRISPR System Using Targetable or Controllable Nanocarriers
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  65. CRISPR/Cas9 in the era of nanomedicine and synthetic biology
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  66. CRISPR/dCas9-Mediated Gene Silencing in Two Plant Fungal Pathogens
    Yun-mu Zhang, Lu Zheng, Kabin Xie · 2023 · mSphere
  67. Repurposing CRISPR/Cas to Discover SARS‐CoV‐2 Detecting and Neutralizing Aptamers
    Ju Zhang, Airu Zhu, Miao Mei, Jing Tao Qu, Yalan Huang, Yongshi Shi, Meiying Xue, Jingfang Zhang, Renli Zhang, Bing Zhou et al. · 2023 · Advanced Science
  68. CRISPRa‐based activation of Fgf21 and Fndc5 ameliorates obesity by promoting adipocytes browning
    Hongtao Zhu, Dan Liu, Ming Sui, Meiling Zhou, Beibei Wang, Qinqin Qi, Ting Wang, Guo Zhang, Feng Wan, Bin Zhang · 2023 · Clinical and Translational Medicine
  69. CRISPR/Cas9-mediated multiple single guide RNAs potently abrogate pseudorabies virus replication
    Yan‐Dong Tang, Ji-Ting Liu, Tong-Yun Wang, Mingxia Sun, Zhi‐Jun Tian, Xuehui Cai · 2017 · Archives of Virology
  70. Dynamic genome and transcriptional network‐based biomarkers and drugs: precision in breast cancer therapy
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  71. E7-Targeted Nanotherapeutics for Key HPV Afflicted Cervical Lesions by Employing CRISPR/Cas9 and Poly (Beta-Amino Ester)
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  72. Programmable targeted epigenetic editing using CRISPR system in Bombyx mori
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  73. Emerging RNA Suppression Technologies to Protect Citrus Trees From Citrus Greening Disease Bacteria
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  74. TriTag: an integrative tool to correlate chromatin dynamics and gene expression in living cells
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  75. New Editing Tools for Gene Therapy in Inherited Retinal Dystrophies
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  76. Tips, Tricks, and Potential Pitfalls of CRISPR Genome Editing in Saccharomyces cerevisiae
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  77. Applications of Anti-CRISPR Proteins in Genome Editing and Biotechnology
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  78. Elongation roadblocks mediated by dCas9 across human genes modulate transcription and nascent RNA processing
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  79. Application of the CRISPR/Cas System for Generation of Pathogen-Resistant Plants
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  83. CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish
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  86. CRISPR Transcriptional Activation Analysis Unmasks an Occult γ-Secretase Processivity Defect in Familial Alzheimer’s Disease Skin Fibroblasts
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  89. CRISPR/Cas9 gene drive technology to control transmission of vector‐borne parasitic infections
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  90. FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells
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  92. Targeting G-quadruplex Forming Sequences with Cas9
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  95. Screening Techniques for Drug Discovery in Alzheimer’s Disease
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  97. CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9
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  98. The ability of SAMHD1 to block HIV-1 but not SIV requires expression of MxB
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  100. Dynamic properties of transcriptional condensates modulate CRISPRa-mediated gene activation
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