Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation
Cited by (834)
Items 101–200 of 834
- Advanced CRISPR/Cas-based genome editing tools for microbial biofuels production: A reviewSabarathinam Shanmugam, Huu Hao Ngo, Yi‐Rui Wu · 2019 · Renewable Energy
- Rapid detection of African swine fever virus using Cas12a-based portable paper diagnosticsShuhan Lu, Fang Li, Qiubing Chen, Jing Wu, Junyi Duan, Xinlin Lei, Ying Zhang, Dongming Zhao, Zhigao Bu, Hao Yin · 2020 · Cell Discovery
- Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas systemNathan H. Kipniss, P.C. Dave P. Dingal, Timothy R. Abbott, Yuchen Gao, Haifeng Wang, Antonia A. Dominguez, Louai Labanieh, Lei S. Qi · 2017 · Nature Communications
- CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulationWujin Sun, Jinqiang Wang, Quanyin Hu, Xingwu Zhou, Ali Khademhosseini, Zhen Gu · 2020 · Science Advances
- CRISPR/Cas approach: A new way of looking at plant-abiotic interactionsMuntazir Mushtaq, Javaid Akhter Bhat, Zahoor Ahmad Mir, Afreen Sakina, Sajad Ali, Anil Kumar Singh, Anshika Tyagi, Romesh Kumar Salgotra, Ajaz Ahmad Dar, Rohini Bhat · 2018 · Journal of Plant Physiology
- G-tract RNA removes Polycomb repressive complex 2 from genesManuel Beltran-Nebot, Manuel Tavares, Neil Justin, Garima Khandelwal, John C. Ambrose, Benjamin M. Foster, Kaylee B. Worlock, Andrey Tvardovskiy, Simone Kunzelmann, Javier Herrero et al. · 2019 · Nature Structural & Molecular Biology
- Optogenetic Immunomodulation: Shedding Light on Antitumor ImmunityPeng Tan, Lian He, Gang Han, Yubin Zhou · 2016 · Trends in biotechnology
- Editing the genome of hiPSC with CRISPR/Cas9: disease modelsAndrew Roger Bassett · 2017 · Mammalian Genome
- A versatile toolkit for CRISPR-Cas13-based RNA manipulation in DrosophilaNhan Huynh, Noah Depner, Raegan T. Larson, Kirst King‐Jones · 2020 · Genome biology
- CRISPR-based genomic tools for the manipulation of genetically intractable microorganismsRebecca S. Shapiro, Alejandro Chavez, James J. Collins · 2018 · Nature Reviews Microbiology
- Thermochemical wastewater valorization via enhanced microbial toxicity toleranceLahiru Niroshan Jayakody, Christopher W. Johnson, Jason M. Whitham, Richard J. Giannone, Brenna A. Black, Nicholas S. Cleveland, Dawn M. Klingeman, William E. Michener, Jessica L. Olstad, Derek R. Vardon et al. · 2018 · Energy & Environmental Science
- Cationic Polymer‐Mediated CRISPR/Cas9 Plasmid Delivery for Genome EditingZhen Zhang, Tao Yu Wan, Yuxuan Chen, Yu Chen, Hong‐Wei Sun, Tianqi Cao, Zhou Songyang, Guping Tang, Chuanbin Wu, Ping Yuan et al. · 2018 · Macromolecular Rapid Communications
- Systemic Delivery of CRISPR/Cas9 Targeting HPV Oncogenes Is Effective at Eliminating Established TumorsLuqman Jubair, Sora Fallaha, Nigel A.J. McMillan · 2019 · Molecular Therapy
- CRISPR-based tools for targeted transcriptional and epigenetic regulation in plantsJoanne E. Lee, Manuela Neumann, Daniel Iglesias Duro, Markus Schmid · 2019 · PLoS ONE
- Introducing Therioepistemology: the study of how knowledge is gained from animal researchJoseph Paul Garner, Brianna N. Gaskill, Elin M. Weber, Jamie Ahloy Dallaire, Kathleen R. Pritchett‐Corning · 2017 · Lab Animal
- CRISPR-assisted multi-dimensional regulation for fine-tuning gene expression in Bacillus subtilisZhenghui Lu, Shihui Yang, Xin Yuan, Yunyun Shi, Li Ouyang, Sijing Jiang, Yi Li, Guimin Zhang · 2019 · Nucleic Acids Research
- Improving CRISPR Genome Editing by Engineering Guide RNAsSu Bin Moon, Do Yon Kim, Jin‐Soo Kim, Jin‐Soo Kim, Yong-Sam Kim · 2019 · Trends in biotechnology
- CRISPR/Cas9 in plant biotechnology: applications and challengesWen Cong Gan, Anna Pick Kiong Ling · 2022 · Biotechnologia
- Edit at will: Genotype independent plant transformation in the era of advanced genomics and genome editingAlbert Paul Kausch, Kimberly Nelson‐Vasilchik, Joel P. Hague, Muruganantham Mookkan, Hector D. Quemada, Stephen L. Dellaporta, Christopher Fragoso, Zhanyuan J. Zhang · 2019 · Plant Science
- Coupling immunity and programmed cell suicide in prokaryotes: Life‐or‐death choicesEugene V. Koonin, Feng Zhang · 2016 · BioEssays
- Functional Genomics via CRISPR–CasKyle M. Ford, Daniella McDonald, Prashant Mali · 2018 · Journal of Molecular Biology
- A split CRISPR–Cpf1 platform for inducible genome editing and gene activationYuta Nihongaki, Takahiro Otabe, Yoshibumi Ueda, Moritoshi Sato · 2019 · Nature Chemical Biology
- CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future ChallengesMuntazir Mushtaq, Aejaz Ahmad Dar, Milan Skalický, Anshika Tyagi, Nancy Bhagat, Umer Basu, Basharat Ahmad Bhat, Abbu Zaid, Sajad Ali, Tanvir Ul Hassan Dar et al. · 2021 · Genes
- A universal deep-learning model for zinc finger design enables transcription factor reprogrammingDavid M. Ichikawa, Osama Abdin, Nader Alerasool, Manjunatha Kogenaru, April L. Mueller, Han Wen, David O. Giganti, Gregory W. Goldberg, Samantha Adams, Jeffrey M. Spencer et al. · 2023 · Nature Biotechnology
- Engineering Escherichia coli for malate production by integrating modular pathway characterization with CRISPRi‐guided multiplexed metabolic tuningCong Gao, Shihui Wang, Guipeng Hu, Liang Guo, Xiulai Chen, Peng Xu, Li Liu · 2017 · Biotechnology and Bioengineering
- HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Natronobacterium gregoryi ArgonauteYeh‐Hsing Lao, Mingqiang Li, Madeleine A. Gao, Dan Shao, Chun‐Wei Chi, Dantong Huang, Syandan Chakraborty, Tzu‐Chieh Ho, Weiqian Jiang, Hongxia Wang et al. · 2018 · Advanced Science
- Multiple Input Sensing and Signal Integration Using a Split Cas12a SystemHannah R. Kempton, Laine Goudy, Kasey S. Love, Lei S. Qi · 2020 · Molecular Cell
- Application of CRISPR/Cas9 to human-induced pluripotent stem cells: from gene editing to drug discoveryClaudia De Masi, Paola Spitalieri, Michela Murdocca, Giuseppe Novelli, Federica Carla Sangiuolo · 2020 · Human Genomics
- Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programsQuentin R. V. Ferry, Radostina Lyutova, Tudor A. Fulga · 2017 · Nature Communications
- Light‐Controlled Mammalian Cells and Their Therapeutic Applications in Synthetic BiologyMaysam Mansouri, Tobias Strittmatter, Martin Fussenegger · 2018 · Advanced Science
- Advances in plant materials, food by-products, and algae conversion into biofuels: use of environmentally friendly technologiesMohammad Hassan Kamani, İsmail Eş, José Manuel Lorenzo, Fabienne Remize, Elena Roselló‐Soto, Francisco J. Barba, James H. Clark, Amin Mousavi Khaneghah · 2019 · Green Chemistry
- Optimization of genome editing through CRISPR-Cas9 engineeringJian-Hua Zhang, Poorni R. Adikaram, Mritunjay Pandey, Allison Genis, William F. Simonds · 2016 · Bioengineered
- The role of long non-coding RNAs in rheumatic diseasesYuanjia Tang, Tian Zhou, Xiang Yu, Zhixin Xue, Nan Shen · 2017 · Nature Reviews Rheumatology
- Genetic Engineering: A Promising Tool to Engender Physiological, Biochemical, and Molecular Stress Resilience in Green MicroalgaeFreddy Guihéneuf, Asif Ali Khan, Lam‐Son Phan Tran · 2016 · Frontiers in Plant Science
- CRISPR-Cas9 library screening approach for anti-cancer drug discovery: overview and perspectivesYau-Tuen Chan, Yuanjun Lu, Junyu Wu, Cheng Zhang, Hor‐Yue Tan, Zhaoxiang Bian, Ning Wang, Yibin Feng · 2022 · Theranostics
- The Importance of Patient-Specific Factors for Hepatic Drug Response and ToxicityVolker Martin Lauschke, Magnus Ingelman‐Sundberg · 2016 · International Journal of Molecular Sciences
- Efficient genome engineering approaches for the short-lived African turquoise killifishItamar Harel, Dario Riccardo Valenzano, Anne Brunet · 2016 · Nature Protocols
- Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCsAlessandro Bertero, Matthias Pawlowski, Daniel Ortmann, Kirsten E Snijders, Loukia Yiangou, Miguel Cardoso de Brito, Stephanie Emma Brown, William George Bernard, James D. Cooper, Elisa Giacomelli et al. · 2016 · Development
- Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging TechnologiesSpencer C. Knight, Robert Tjian, Jennifer A. Doudna · 2017 · Angewandte Chemie International Edition
- Next-generation metabolic engineering approaches towards development of plant cell suspension cultures as specialized metabolite producing biofactoriesSagar S. Arya, James Edward Rookes, David Miles Cahill, Sangram Keshari Lenka · 2020 · Biotechnology Advances
- CRISPR: gene editing is just the beginningHeidi K. Ledford · 2016 · Nature
- Genome editing in crop improvement: Present scenario and future prospectsGurbachan S. Miglani · 2017 · Journal of Crop Improvement
- CRISPR-Cas12-based nucleic acids detection systemsRoss Ka‐Kit Leung, Qiuxiang Cheng, Zhile Wu, Gulfaraz Khan, Yang Liu, Haiyang Xia, Jin Wang · 2021 · Methods
- Signaling pathways regulating cartilage growth plate formation and activityWilliam E. Samsa, Xin Zhou, Guang Dong Zhou · 2016 · Seminars in Cell and Developmental Biology
- Human pluripotent stem cell–derived models and drug screening in CNS precision medicineM. Catarina Silva, Stephen J. Haggarty · 2019 · Annals of the New York Academy of Sciences
- Genetic and epigenetic control of gene expression by CRISPR–Cas systemsAlbert Lo, Lei S. Qi · 2017 · F1000Research
- Antiviral Goes Viral: Harnessing CRISPR/Cas9 to Combat Viruses in HumansJasper A. Soppe, Robert Jan Lebbink · 2017 · Trends in Microbiology
- Engineering Synthetic Signaling Pathways with Programmable dCas9-Based Chimeric ReceptorsToni A. Baeumler, Ahmed A. Ahmed, Tudor A. Fulga · 2017 · Cell Reports
- CRISPR Therapeutics for Duchenne Muscular DystrophyEsra J. N. Erkut, Toshifumi Yokota · 2022 · International Journal of Molecular Sciences
- CRISPR/dCas9-mediated biosensor for detection of tick-borne diseasesBonhan Koo, Jin‐Soo Kim, Jiyeon Kweon, Choong Eun Jin, Sung‐Han Kim, Yongsub Kim, Yong Moon Shin · 2018 · Sensors and Actuators B Chemical
- Programmable DNA looping using engineered bivalent dCas9 complexesNan Hao, Keith Edward Shearwin, Ian B. Dodd · 2017 · Nature Communications
- Light‐Induced Dimerization Approaches to Control Cellular ProcessesLaura Klewer, Yao‐Wen Wu · 2019 · Chemistry - A European Journal
- Modulating gene regulation to treat genetic disordersNavneet Kaur Matharu, Nadav Ahituv · 2020 · Nature Reviews Drug Discovery
- Model-guided dynamic control of essential metabolic nodes boosts acetyl-coenzyme A–dependent bioproduction in rewired Pseudomonas putidaEkaterina Kozaeva, Svetlana Volkova, Marta R. A. Matos, Mariela P. Mezzina, Tune Wulff, Daniel C. Volke, Lars Keld Nielsen, Pablo I. Nikel · 2021 · Metabolic Engineering
- Neurotrophin Signaling and Stem Cells—Implications for Neurodegenerative Diseases and Stem Cell TherapySubrata Pramanik, Yanuar Alan Sulistio, Klaus Heese · 2016 · Molecular Neurobiology
- Lessons from Enzyme Kinetics Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome EditingNamita Bisaria, Inga Jarmoskaite, Daniel Herschlag · 2017 · Cell Systems
- CRISPR/Cas systems for the detection of nucleic acid and non-nucleic acid targetsWeiran Su, Junru Li, Ji Chen, Congshuo Chen, Yuzheng Wang, Huili Dai, Fengqin Li, Peifeng Liu · 2023 · Nano Research
- Cutting back malaria: CRISPR/Cas9 genome editing of PlasmodiumLee M, Scott E. Lindner, José-Juan Lopez-Rubio, Manuel Llinás · 2019 · Briefings in Functional Genomics
- A redox-based electrogenetic CRISPR system to connect with and control biological information networksNarendranath Bhokisham, Eric S. VanArsdale, Kristina Stephens, Pricila Hauk, Gregory Francis Payne, William E. Bentley · 2020 · Nature Communications
- Live cell imaging of genomic loci using dCas9-SunTag system and a bright fluorescent proteinHuiying Ye, Zhili Rong, Ying Lin · 2017 · Protein & Cell
- Drug-tunable multidimensional synthetic gene control using inducible degron-tagged dCas9 effectorsDirk A. Kleinjan, Caroline Wardrope, Si Nga Sou, Susan J. Rosser · 2017 · Nature Communications
- Comparison and optimization of CRISPR/dCas9/gRNA genome-labeling systems for live cell imagingYu Hong, Guangqing Lu, Jinzhi Duan, Wenjing Liu, Yu Zhang · 2018 · Genome biology
- CRISPR/Cas9 technology for improving agronomic traits and future prospective in agricultureMuhammad Junaid Rao, Lingqiang Wang · 2021 · Planta
- Inducible expression of large gRNA arrays for multiplexed CRISPRai applicationsWilliam M. Shaw, Lucie Studená, Kyler Roy, Piotr Hapeta, Nicholas S. McCarty, Alicia E. Graham, Tom Ellis, Rodrigo Ledesma‐Amaro · 2022 · Nature Communications
- CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospectsCésar de la Fuente‐Núñez, Timothy K. Lu · 2016 · Integrative Biology
- Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressorsHong Wang, Rui Guo, Zhonghua Du, Ling Bai, Lingyu Li, Jiuwei Cui, Wei Li, Andrew R. Hoffman, Ji‐Fan Hu · 2018 · Molecular Therapy — Nucleic Acids
- A versatile, high-efficiency platform for CRISPR-based gene activationAmy J. Heidersbach, Kristel M. Dorighi, Javier A. Gomez, Ashley M. Jacobi, Benjamin Haley · 2023 · Nature Communications
- Insecticide resistance mediated by an exon skipping eventMadeleine Berger, Alin Mirel Puinean, Emma L. Randall, Christoph T. Zimmer, Wellington Marcos da Silva, Pablo Bielza, L. M. Field, David Hughes, Ian R. Mellor, Keywan Hassani‐Pak et al. · 2016 · Molecular Ecology
- A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicansLauren F. Wensing, Jehoshua Sharma, Deeva Uthayakumar, Yannic Proteau, Alejandro Chavez, Rebecca S. Shapiro · 2019 · mSphere
- Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variantsEszter Tóth, Bernadett C Czene, Péter István Kulcsár, Sarah L Krausz, András Tálas, Antal Nyeste, Éva Varga, Krisztina Huszár, Nóra Weinhardt, Zoltán Ligeti et al. · 2018 · Nucleic Acids Research
- CRISPR-based Activation of Endogenous Neurotrophic Genes in Adipose Stem Cell Sheets to Stimulate Peripheral Nerve RegenerationMu‐Nung Hsu, Han-Tsung Liao, Vu Anh Truong, Kai-Lun Huang, Fu-Jen Yu, Hwei‐Hsien Chen, Thị Kieu Nuong Nguyen, П. И. Макаревич, Yelena V. Parfyonova, Yu-Chen Hu · 2019 · Theranostics
- Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugatesXinyu Ling, Liying Chang, Heqi Chen, Xiaoqin Gao, Jianhang Yin, Yi Zuo, Yujia Huang, Bo Zhang, Jiazhi Hu, Tao Liu · 2021 · Molecular Cell
- Muscle cell-derived cytokines in skeletal muscle regenerationR. Waldemer-Streyer, Dongwook Kim, Jie Chen · 2022 · The FEBS Journal
- DNA-free genome editing methods for targeted crop improvementChidananda Nagamangala Kanchiswamy · 2016 · Plant Cell Reports
- Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editingXinyun Jing, Bingran Xie, Longxian Chen, Niubing Zhang, Yiyi Jiang, Hang Qin, Hongbing Wang, Pei Hao, Sheng Yang, Xuan Li · 2018 · Nucleic Acids Research
- Evolving insights into RNA modifications and their functional diversity in the brainSarah Nainar, Paul Robert Marshall, Christina R. Steadman, Robert C. Spitale, Timothy William Bredy · 2016 · Nature Neuroscience
- New breeding technique “genome editing” for crop improvement: applications, potentials and challengesSupriya Babasaheb Aglawe, Kalyani Makarand Barbadikar, Satendra Kumar Mangrauthia, Maganti Sheshu Madhav · 2018 · 3 Biotech
- Large chromosomal segment deletions by CRISPR/LbCpf1‐mediated multiplex gene editing in soybeanKaixuan Duan, Yuanyuan Cheng, Jing Ji, Chenchen Wang, Yongshu Wei, Yuanchao Wang · 2021 · Journal of Integrative Plant Biology
- Next-Generation Diagnostic with CRISPR/Cas: Beyond Nucleic Acid DetectionPooja Bhardwaj, Rajni Kant, Sthita Pragnya Behera, Gaurav Raj Dwivedi, Rajeev Singh · 2022 · International Journal of Molecular Sciences
- Insights into epileptogenesis from post-traumatic epilepsyMatthew W. Pease, Kunal Gupta, Solomon L. Moshé, Daniel José Correa, Aristea S. Galanopoulou, David O. Okonkwo, Jorge Alvaro Gonzalez-Martinez, Lori Shutter, Ramon R. Diaz-Arrastia, James F. Castellano · 2024 · Nature Reviews Neurology
- Drug Inducible CRISPR/Cas SystemsJingfang Zhang, Li Chen, Ju Zhang, Yu Wang · 2019 · Computational and Structural Biotechnology Journal
- Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer managementKhaled S. Allemailem, Mohammed A. Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan · 2022 · 癌症:英文版
- Optimized Cas9 expression systems for highly efficient Arabidopsis genome editing facilitate isolation of complex alleles in a single generationJana Ordon, Mauro Bressan, Carola Kretschmer, Luca Dall’Osto, Sylvestre Marillonnet, Roberto Bassi, Johannes Stuttmann · 2019 · Functional & Integrative Genomics
- The use of new CRISPR tools in cardiovascular research and medicineMasataka Nishiga, Chun Liu, Lei S. Qi, Joseph C. Wu · 2022 · Nature Reviews Cardiology
- Organoid technologies meet genome engineeringJing Nie, Eri Hashino · 2017 · EMBO Reports
- Gene editing by CRISPR/Cas9 in the obligatory outcrossing Medicago sativaRuimin Gao, Biruk A. Feyissa, Mana Croft, Abdelali Hannoufa · 2018 · Planta
- Noncoding RNAs: Stress, Glucocorticoids, and Posttraumatic Stress DisorderNikolaos P. Daskalakis, Allison C. Provost, Richard G Hunter, Guia Guffanti · 2018 · Biological Psychiatry
- Characterization and Repurposing of Type I and Type II CRISPR–Cas Systems in BacteriaHidalgo-Cantabrana, Claudio, Goh, Yong Jun, Barrangou, Rodolphe · 2019 · Journal of Molecular Biology
- Applying CRISPR–Cas9 tools to identify and characterize transcriptional enhancersRui Lopes, Gözde Korkmaz, Reuven Agami · 2016 · Nature Reviews Molecular Cell Biology
- CRISPR/Cas9-Mediated Gene Correction to Understand ALSYeomin Yun, Yoon Ha · 2020 · International Journal of Molecular Sciences
- Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing ReadoutUdit Parekh, Yan Wu, Dongxin Zhao, Atharv Worlikar, Neha Shah, Kun Zhang, Prashant Mali · 2018 · Cell Systems
- Reversible Disruption of Specific Transcription Factor-DNA Interactions Using CRISPR/Cas9S. Ali Shariati, Antonia A. Dominguez, Shicong Xie, Marius Wernig, Lei S. Qi, Jan Marcel Skotheim · 2019 · Molecular Cell
- The Challenges to Advancing Induced Pluripotent Stem Cell-Dependent Cell Replacement TherapyAlan B. Moy, Anant M. Kamath, Sara Ternes, Jay Kamath · 2023 · Medical Research Archives
- An Overview of CRISPR-Based Tools and Their Improvements: New Opportunities in Understanding Plant–Pathogen Interactions for Better Crop ProtectionAbdellah Barakate, Jennifer Stephens · 2016 · Frontiers in Plant Science
- Regulated Expression of sgRNAs Tunes CRISPRi in E. coliJason T. Fontana, Chen Dong, Jennifer Y. Ham, Jesse G. Zalatan, James M. Carothers · 2018 · Biotechnology Journal
- Engineering multicellular systems: Using synthetic biology to control tissue self-organizationMarion B. Johnson, Alexander R. March, Leonardo Morsut · 2017 · Current Opinion in Biomedical Engineering
- CRISPR-Cas gene editing technology and its application prospect in medicinal plantsMiaoxian Guo, Hongyu Chen, Shuting Dong, Zheng Zhang, Hongmei Luo · 2022 · Chinese Medicine
- A ‘poly-transfection’ method for rapid, one-pot characterization and optimization of genetic systemsJeremy J Gam, Breanna DiAndreth, Ross D. Jones, Jin H. Huh, Ron Weiss · 2019 · Nucleic Acids Research
- Discovering and validating cancer genetic dependencies: approaches and pitfallsAnn Lin, Jason M. Sheltzer · 2020 · Nature Reviews Genetics
- Engineering 3D genome organizationHaifeng Wang, Mengting Han, Lei S. Qi · 2021 · Nature Reviews Genetics