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Cited by 228

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

Chaperoning SNARE assembly and disassembly

Open access
Baker, Richard W., Hughson, Frederick M.·2016·Nature Reviews Molecular Cell Biology

Abstract

Intracellular membrane fusion is mediated in most cases by membrane-bridging complexes of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). However, the assembly of such complexes in vitro is inefficient, and their uncatalysed disassembly is undetectably slow. Here, we focus on the cellular machinery that orchestrates assembly and disassembly of SNARE complexes, thereby regulating processes ranging from vesicle trafficking to organelle fusion to neurotransmitter release. Rapid progress is being made on many fronts, including the development of more realistic cell-free reconstitutions, the application of single-molecule biophysics, and the elucidation of X-ray and high-resolution electron microscopy structures of the SNARE assembly and disassembly machineries 'in action'.

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Metadata

Authors
Baker, R. W., & Hughson, F. M.
Venue
Nature Reviews Molecular Cell Biology
Published
2016-06-15
Volume
17
Issue
8
Pages
465-479
ISSN
  • 1471-0072 (ISSN-L)
  • 1471-0080
OpenAlex
W2441542994
Cited by
228
References
10
FWCI
2.46
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Chaperoning SNARE assembly and disassembly. https://app.cochat.ai/papers/10.1038/nrm.2016.65
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Baker, R. W., & Hughson, F. M. (2016). Chaperoning SNARE assembly and disassembly. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/nrm.2016.65

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.