Codon optimality, bias and usage in translation and mRNA decay

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

Ingolia, N. T., Ghaemmaghami, S., Newman, J. R. S., & Weissman, J. S. (2009) · Science · doi:10.1126/science.1168978 · Cited by 3,853

Global analysis of protein expression in yeast

Ghaemmaghami, S., Huh, W.-K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., & Weissman, J. S. (2003) · Nature · doi:10.1038/nature02046 · Cited by 3,750

Regulation of mRNA Translation and Stability by microRNAs

Fabian, M. R., Sonenberg, N., & Filipowicz, W. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060308-103103 · Cited by 3,214

Synonymous but not the same: the causes and consequences of codon bias

Plotkin, J. B., & Kudla, G. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2899 · Cited by 1,722

Coding-Sequence Determinants of Gene Expression in Escherichia coli

Kudla, G., Murray, A. W., Tollervey, D., & Plotkin, J. B. (2009) · Science · doi:10.1126/science.1170160 · Cited by 1,458

Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes: A proposal for a synonymous codon choice that is optimal for the E. coli translational system

Ikemura, T. (1981) · Journal of Molecular Biology · doi:10.1016/0022-2836(81)90003-6 · Cited by 1,423

Codon bias and heterologous protein expression

Gustafsson, C., Govindarajan, S., & Minshull, J. (2004) · Trends in Biotechnology · doi:10.1016/j.tibtech.2004.04.006 · Cited by 1,330

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Hsieh, A. C., Liu, Y., Edlind, M. P., Ingolia, N. T., Janes, M. R., Sher, A., Shi, E. Y., Stumpf, C. R., Christensen, C., Bonham, M. J., et al. (2012) · Nature · doi:10.1038/nature10912 · Cited by 1,313

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

Li, G., Burkhardt, D. H., Gross, C. A., & Weissman, J. S. (2014) · Cell · doi:10.1016/j.cell.2014.02.033 · Cited by 1,259

Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation

Lu, P., Vogel, C., Wang, R., Yao, X., & Marcotte, E. M. (2007) · Nature Biotechnology · doi:10.1038/nbt1270 · Cited by 1,139

Plastomes of Bletilla (Orchidaceae) and Phylogenetic Implications

Han, S., Wang, R., Hong, X., Wu, C., Zhang, S., & Kan, X. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231710151 · Cited by 30

Robustness by intrinsically disordered C-termini and translational readthrough

Kleppe, A. S., & Bornberg‐Bauer, E. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky778 · Cited by 31

Translation Regulation in Skin Cancer from a tRNA Point of View

Grafanaki, K., Anastasakis, D. G., Kyriakopoulos, G. C., Skeparnias, I., Georgiou, S., & Stathopoulos, C. (2018) · Epigenomics · doi:10.2217/epi-2018-0176 · Cited by 31

Conserved Methyltransferase Spb1 Targets mRNAs for Regulated Modification with 2′-O-Methyl RibosePreprint

Bartoli, K. M., Schaening-Burgos, C., Carlile, T. M., & Gilbert, W. V. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/271916 · Cited by 30

Integrated analyses of translatome and proteome identify the rules of translation selectivity in RPS14-deficient cells

Boussaid, I., Goff, S. L., Floquet, C., Gautier, E., Raimbault, A., Viailly, P., Dulaimi, D. A., Burroni, B., Dusanter‐Fourt, I., Hatin, I., et al. (2020) · Haematologica · doi:10.3324/haematol.2019.239970 · Cited by 30

Splicing-accessible coding 3′UTRs control protein stability and interaction networks

Preußner, M., Gao, Q., Morrison, E., Herdt, O., Finkernagel, F., Schümann, M., Krause, E., Freund, C., Chen, W., & Heyd, F. (2020) · Genome biology · doi:10.1186/s13059-020-02102-3 · Cited by 29

Principles of mRNA control by human PUM proteins elucidated from multimodal experiments and integrative data analysis

Wolfe, M. B., Schagat, T. L., Paulsen, M. T., Magnuson, B., Ljungman, M., Park, D., Zhang, C., Campbell, Z. T., Goldstrohm, A. C., & Freddolino, P. L. (2020) · RNA · doi:10.1261/rna.077362.120 · Cited by 22

The ribosome as a platform to coordinate mRNA decay

Müller, M. B. D., Becker, T. A., Denk, T., Hashimoto, S., Inada, T., & Beckmann, R. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf049 · Cited by 31

Codon optimization significantly enhanced the expression of human 37-kDa iLRP in Escherichia coli

Liu, B., Kong, Q., Zhang, D., & Yan, L. (2018) · 3 Biotech · doi:10.1007/s13205-018-1234-y · Cited by 28

Stable G-quadruplex enabling sequences are selected against by the context-dependent codon bias

Arachchilage, G. M., Arachchilage, M. H., Venkataraman, A., Piontkivska, H., & Basu, S. (2019) · Gene · doi:10.1016/j.gene.2019.02.006 · Cited by 27

Regulatory roles of RNA modifications in breast cancer

Kumari, K., Groza, P., & Aguiló, F. (2021) · NAR Cancer · doi:10.1093/narcan/zcab036 · Cited by 30

Codon optimality in cancer

Gillen, S. L., Waldron, J. A., & Bushell, M. (2021) · Oncogene · doi:10.1038/s41388-021-02022-x · Cited by 31

A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription

Li, H., Han, D. H., Xu, B., Xiong, Q., Li, C., Yang, W., Li, J., Huang, Z., Zeng, Q., Wang, E., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2021108544 · Cited by 28

RBM33 directs the nuclear export of transcripts containing GC-rich elementsPreprint

Thomas, A. A., Rehfeld, F., Zhang, H., Chang, T.-C., Goodarzi, M., Gillett, F. A., & Mendell, J. T. (2022) · Genes & Development · doi:10.1101/gad.349456.122 · Cited by 30

mRNA therapeutics: Transforming medicine through innovation in design, delivery, and disease treatment

Ige, M. A., Ren, X., Yang, Y., Zhang, H., Shen, C., Jiang, Y., Li, J., & Wan, X. (2025) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2025.102721 · Cited by 30

Transcriptomes of Trypanosoma brucei rhodesiense from sleeping sickness patients, rodents and culture: Effects of strain, growth conditions and RNA preparation methods

Mulindwa, J., Leiss, K., Ibberson, D., Marucha, K. K., Helbig, C., do Nascimento, L. M., Silvester, E., Matthews, K. R., Matovu, E., Enyaru, J., et al. (2018) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0006280 · Cited by 25

Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models

Uchida, N., Li, L., Nassehi, T., Drysdale, C. M., Yapundich, M., Gamer, J., Haro‐Mora, J. J., Demirci, S., Leonard, A. K., Bonifacino, A. C., et al. (2021) · Cell Reports Medicine · doi:10.1016/j.xcrm.2021.100247 · Cited by 28

Pan-cancer atlas of somatic core and linker histone mutations

Bonner, E. R., Dawood, A., Gordish‐Dressman, H., Eze, A., Bhattacharya, S., Yadavilli, S., Mueller, S. C., Waszak, S. M., & Nazarian, J. (2023) · npj Genomic Medicine · doi:10.1038/s41525-023-00367-8 · Cited by 26

Deep generative optimization of mRNA codon sequences for enhanced mRNA translation and therapeutic efficacy

Li, Y., Wang, F., Yang, J., Han, Z., Chen, L., Jiang, W., Zhou, H., Li, T., Tang, Z., Deng, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-64894-x · Cited by 37

Recent Advancements in mRNA Vaccines: From Target Selection to Delivery Systems

Wu, Z., Sun, W., & Qi, H. (2024) · Vaccines · doi:10.3390/vaccines12080873 · Cited by 30

Molecular targets and strategies in the development of nucleic acid cancer vaccines: from shared to personalized antigens

Chi, W.-Y., Hu, Y., Huang, H., Kuo, H., Lin, S., Kuo, C.-T. J., Tao, J., Fan, D., Huang, Y.-M., Wu, A. A., et al. (2024) · Journal of Biomedical Science · doi:10.1186/s12929-024-01082-x · Cited by 27

COSMO: A dynamic programming algorithm for multicriteria codon optimization

Taneda, A., & Asai, K. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2020.06.035 · Cited by 24

The interface between coronaviruses and host cell RNA biology: Novel potential insights for future therapeutic intervention

Maranon, D. G., Anderson, J. R., Maranon, A. G., & Wilusz, J. (2020) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1614 · Cited by 22

Analysis of 11,430 recombinant protein production experiments reveals that protein yield is tunable by synonymous codon changes of translation initiation sites

Bhandari, B. K., Lim, C. S., Remus, D. M., Chen, A., van Dolleweerd, C. J., & Gardner, P. P. (2021) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1009461 · Cited by 26

Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay

Martin, S., Allan, K. C., Pinkard, O. W., Sweet, T. J., Tesar, P. J., & Coller, J. (2022) · Nature Communications · doi:10.1038/s41467-022-32766-3 · Cited by 25

Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach

Goyal, F., Chattopadhyay, A., Navik, U., Jain, A., Reddy, P. H., Bhatti, G. K., & Bhatti, J. S. (2023) · Advanced Therapeutics · doi:10.1002/adtp.202300255 · Cited by 25

Human DDX6 regulates translation and decay of inefficiently translated mRNAs

Weber, R., & Chang, C.-T. (2024) · eLife · doi:10.7554/elife.92426 · Cited by 23

Global SLAM-seq for accurate mRNA decay determination and identification of NMD targets

Alalam, H., Zepeda-Martínez, J. A., & Sunnerhagen, P. (2022) · RNA · doi:10.1261/rna.079077.121 · Cited by 23

Cell-type specific polysome profiling from mammalian tissues

Seimetz, J. W., Arif, W., Bangru, S., Hernáez, M., & Kalsotra, A. (2018) · Methods · doi:10.1016/j.ymeth.2018.11.015 · Cited by 26

The Deoptimization of Rabies Virus Matrix Protein Impacts Viral Transcription and Replication

Luo, J., Zhang, Y., Zhang, Q., Wu, Y., Zhang, B., Mo, M., Qin, T., Zhao, J., Mei, M., & Guo, X. (2019) · Viruses · doi:10.3390/v12010004 · Cited by 23

Electroacupuncture attenuates ac4C modification of P16 mRNA in the ovarian granulosa cells of a mouse model premature ovarian failure

Geng, Z., Liu, P., Yuan, L., Zhang, K., Lin, J., Nie, X., Jiang, H., Li, B., Liu, T., & Zhang, B. (2022) · Acupuncture in Medicine · doi:10.1177/09645284221085284 · Cited by 22

Implementing computational methods in tandem with synonymous gene recoding for therapeutic development

Lin, B. C., Kaissarian, N. M., & Kimchi‐Sarfaty, C. (2022) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2022.09.008 · Cited by 21

Genome-wide sequencing identifies a thermal-tolerance related synonymous mutation in the mussel, Mytilisepta virgata

Tan, Y., Ma, C., Li, X., Han, G., & Dong, Y. (2023) · Communications Biology · doi:10.1038/s42003-022-04407-4 · Cited by 22

Quality control of protein synthesis in the early elongation stage

Nagao, A., Nakanishi, Y., Yamaguchi, Y., Mishina, Y., Karoji, M., Toya, T., Fujita, T., Iwasaki, S., Miyauchi, K., Sakaguchi, Y., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-38077-5 · Cited by 24

The mRNA vaccine, a swift warhead against a moving infectious disease target

Mir, S., & Mir, M. A. (2024) · Expert Review of Vaccines · doi:10.1080/14760584.2024.2320327 · Cited by 28

Decoding Codon Bias: The Role of tRNA Modifications in Tissue-Specific Translation

Ando, D., Rashad, S., Begley, T. J., Endo, H., Aoki, M., Dedon, P. C., & Niizuma, K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26020706 · Cited by 21

Comprehensive Analysis of Codon Usage in Quercus Chloroplast Genome and Focus on psbA Gene

Shi, S.-L., Liu, Y., Xia, R.-X., & Qin, L. (2022) · Genes · doi:10.3390/genes13112156 · Cited by 21

Ultradeep characterisation of translational sequence determinants refutes rare-codon hypothesis and unveils quadruplet base pairing of initiator tRNA and transcript

Höllerer, S., & Jeschek, M. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad040 · Cited by 21

Molecular Evolution of Protein Sequences and Codon Usage in Monkeypox Viruses

Shan, K.-J., Wu, C., Tang, X., Lu, R., Hu, Y., Tan, W., & Lü, J. (2023) · Genomics Proteomics & Bioinformatics · doi:10.1093/gpbjnl/qzad003 · Cited by 23

RNA control in pain: Blame it on the messenger

de la Peña, J. B., Song, J. J., & Campbell, Z. T. (2019) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1546 · Cited by 21

Codon optimization is an essential parameter for the efficient allotopic expression of mtDNA genes

Lewis, C. J., Dixit, B., Batiuk, E., Hall, C. J., O'Connor, M. S., & Boominathan, A. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101429 · Cited by 20

Synthetic genomes with altered genetic codes

Ostrov, N., Nyerges, Á., Chiappino-Pepe, A., Rudolph, A., Baas-Thomas, M. S., & Church, G. M. (2020) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2020.09.007 · Cited by 18

Dengue virus preferentially uses human and mosquito non-optimal codons

Castellano, L. A., McNamara, R. J., Pallarés, H. M., Gamarnik, A. V., Alvarez, D. E., & Bazzini, A. (2024) · Molecular Systems Biology · doi:10.1038/s44320-024-00052-7 · Cited by 20

Posttranscriptional Gene Regulation of the GABA Receptor to Control Neuronal Inhibition

Schieweck, R., & Kiebler, M. A. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00152 · Cited by 20

Direct in vivo observation of the effect of codon usage bias on gene expression in Arabidopsis hybrids

Chu, D., & Wei, L. (2021) · Journal of Plant Physiology · doi:10.1016/j.jplph.2021.153490 · Cited by 19

Frameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance

Wang, X., Dong, Q., Chen, G., Zhang, J., Liu, Y., & Cai, Y. (2022) · BMC Genomics · doi:10.1186/s12864-022-08435-6 · Cited by 19

Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation

Poetz, F., Lebedeva, S., Schott, J., Lindner, D., Ohler, U., & Stoecklin, G. (2022) · Genome biology · doi:10.1186/s13059-022-02760-5 · Cited by 19

Evolution and codon usage bias of mitochondrial and nuclear genomes in Aspergillus section Flavi

Hugaboom, M. B., Hatmaker, E. A., LaBella, A. L., & Rokas, A. (2022) · G3 Genes Genomes Genetics · doi:10.1093/g3journal/jkac285 · Cited by 19

Tissue-specific temperature dependence of RNA editing levels in zebrafish

Li, W., Bu, M., Hu, R., Jiang, S., Chen, L., & Somero, G. N. (2023) · BMC Biology · doi:10.1186/s12915-023-01738-4 · Cited by 19

Comparative Study on Codon Usage Patterns across Chloroplast Genomes of Eighteen Taraxacum Species

Yang, Y., Wang, X., & Shi, Z. (2024) · Horticulturae · doi:10.3390/horticulturae10050492 · Cited by 19

tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development

Rappol, T., Waldl, M., Chugunova, A. A., Hofacker, I. L., Pauli, A., & Vilardo, E. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae595 · Cited by 20

The suppressive cap-binding complex factor 4EIP is required for normal differentiation

Terrão, M. C., Marucha, K. K., Mugo, E., Droll, D., Minia, I., Egler, F., Braun, J., & CLAYTON, C. E. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky733 · Cited by 19

Regulating translation in aging: from global to gene-specific mechanisms

Solyga, M., Majumdar, A., & Besse, F. (2024) · EMBO Reports · doi:10.1038/s44319-024-00315-2 · Cited by 23

Non-Viral RNA Therapies for Non-Small Cell Lung Cancer and Their Corresponding Clinical Trials

Tiwade, P. B., Fung, V., VanKeulen‐Miller, R., Narasipura, E. A., Ma, Y., & Fenton, O. S. (2025) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.4c00871 · Cited by 18

Environment‐driven changes of mRNA and protein levels in Pseudomonas aeruginosa

Erdmann, J., Preuße, M., Khaledi, A., Pich, A., & Häußler, S. (2018) · Environmental Microbiology · doi:10.1111/1462-2920.14419 · Cited by 18

Hidden Aspects of Valency in Immune System Regulation

Samir, P., & Kanneganti, T. (2019) · Trends in Immunology · doi:10.1016/j.it.2019.10.005 · Cited by 19

Massively parallel gene expression variation measurement of a synonymous codon library

Schmitz, A., & Zhang, F. (2021) · BMC Genomics · doi:10.1186/s12864-021-07462-z · Cited by 16

Stability and expression of SARS-CoV-2 spike-protein mutations

Bæk, K. T., Mehra, R., & Kepp, K. P. (2022) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-022-04588-w · Cited by 17

Understanding Protein Functions in the Biological Context

Wang, T., & Zhang, W. (2023) · Protein and Peptide Letters · doi:10.2174/0929866530666230507212638 · Cited by 20

Pervasive translation of Xrn1-sensitive unstable long non-coding RNAs in yeast

Andjus, S., Szachnowski, U., Vogt, N., Gioftsidi, S., Hatin, I., Cornu, D., Papadopoulos, C., Lopes, A., Namy, O., Wéry, M., et al. (2024) · RNA · doi:10.1261/rna.079903.123 · Cited by 18

Synonymous codon substitutions modulate transcription and translation of a divergent upstream gene by modulating antisense RNA production

Rodríguez, A., Diehl, J. D., Wright, G., Bonar, C. D., Lundgren, T. J., Moss, M. J., Li, J., Milenković, T., Huber, P. W., Champion, M. M., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2405510121 · Cited by 17

Codon Usage in the Iflaviridae Family Is Not Diverse Though the Family Members Are Isolated from Diverse Host Taxa

Shi, S.-L., & Xia, R.-X. (2019) · Viruses · doi:10.3390/v11121087 · Cited by 18

Co-evolution between codon usage and protein-protein interaction in bacteria

Dilucca, M., Cimini, G., Forcelloni, S., & Giansanti, A. (2021) · Gene · doi:10.1016/j.gene.2021.145475 · Cited by 18

Protein Abundance Prediction Through Machine Learning Methods

Ferreira, M. A. D. M., Ventorim, R. Z., de Almeida, E. L. M., Silveira, S. D. A., & da Silveira, W. B. (2021) · Journal of Molecular Biology · doi:10.1016/j.jmb.2021.167267 · Cited by 20

Codon-specific ribosome stalling reshapes translational dynamics during branched-chain amino acid starvation

Worpenberg, L., Gobet, C., & Naef, F. (2025) · Genome biology · doi:10.1186/s13059-025-03800-6 · Cited by 20

Incompatible Translation Drives a Convergent Evolution and Viral Attenuation During the Development of Live Attenuated Vaccine

Ou, X., Wang, M., Mao, S., Cao, J., Cheng, A., Zhu, D., Chen, S., Jia, R., Liu, M., Yang, Q., et al. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00249 · Cited by 17

A large-scale analysis of codon usage bias in 4868 bacterial genomes shows association of codon adaptation index with GC content, protein functional domains and bacterial phenotypes

Masłowska-Górnicz, A., van den Bosch, M. R. M., Saccenti, E., & Diez, M. S. (2022) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2022.194826 · Cited by 17

Single-molecule visualization of mRNA circularization during translation

Kim, B., Seol, J., Kim, Y. K., & Lee, J. (2023) · Experimental & Molecular Medicine · doi:10.1038/s12276-023-00933-1 · Cited by 16

Complete mitochondrial genome of Agropyron cristatum reveals gene transfer and RNA editing events

Ou, T., Wu, Z.-N., Tian, C.-Y., Yang, Y.-T., & Li, Z.-Y. (2024) · BMC Plant Biology · doi:10.1186/s12870-024-05558-8 · Cited by 16

Single-cell kinetics of siRNA-mediated mRNA degradation

Krzysztoń, R., Woschée, D., Reiser, A., Schwake, G., Strey, H. H., & Rädler, J. O. (2019) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2019.102077 · Cited by 20

Translation arrest as a protein quality control system for aberrant translation of the 3′‐UTR in mammalian cells

Hashimoto, S., Nobuta, R., Izawa, T., & Inada, T. (2019) · FEBS Letters · doi:10.1002/1873-3468.13362 · Cited by 17

Распределение синонимических кодонов в мРНК определяет путь котрансляционного сворачивания белка в клетке

Komar, A. A. (2019) · Molecular Biology · doi:10.1134/s0026898419060090 · Cited by 20

The Functional Consequences of the Novel Ribosomal Pausing Site in SARS-CoV-2 Spike Glycoprotein RNA

Postnikova, O. A., Uppal, S., Huang, W., Kane, M. A., Villasmil, R., Rogozin, I. B., Poliakov, E., & Redmond, T. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126490 · Cited by 16

DNA methylation differences during development distinguish sympatric morphs of Arctic charr (Salvelinus alpinus)

Matlosz, S., Sigurgeirsson, B., Franzdóttir, S. R., Pálsson, A., & Jónsson, Z. O. (2022) · Molecular Ecology · doi:10.1111/mec.16620 · Cited by 16

Imaging spatiotemporal translation regulation in vivo

Blake, L. A., de la Cruz, A. C., & Wu, B. (2023) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2023.03.006 · Cited by 14

mRNA therapeutics for disease therapy: principles, delivery, and clinical translation

Zhou, D., Wang, K., Zhang, Y., Ma, K., Yang, X., Li, Z.-Y., Yu, S., Chen, K., & Qiao, S. (2023) · Journal of Materials Chemistry B · doi:10.1039/d2tb02782h · Cited by 18

Essential factors, advanced strategies, challenges, and approaches involved for efficient expression of recombinant proteins in Escherichia coli

Eskandari, A., Nezhad, N. G., Leow, T. C., Rahman, M. B. A., & Oslan, S. N. (2024) · Archives of Microbiology · doi:10.1007/s00203-024-03871-2 · Cited by 16

Learning from the Codon Table: Convergent Recoding Provides Novel Understanding on the Evolution of A-to-I RNA Editing

Ma, L., Zheng, C., Liu, J., Song, F., Tian, L., Cai, W., Li, H., & Duan, Y. (2024) · Journal of Molecular Evolution · doi:10.1007/s00239-024-10190-z · Cited by 16

Unveiling RNA structure-mediated regulations of RNA stability in wheat

Wu, H., Yu, H., Zhang, Y., Yang, B., Sun, W., Ren, L., Li, Y., Li, Q., Liu, B., Ding, Y., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54172-7 · Cited by 17

Emerging Roles of Translational Control in Circadian Timekeeping

Castelo-Szekely, V., & Gatfield, D. (2020) · Journal of Molecular Biology · doi:10.1016/j.jmb.2020.03.023 · Cited by 17

CUBAP: an interactive web portal for analyzing codon usage biases across populations

Hodgman, M. W., Miller, J. B., Meurs, T. E., & Kauwe, J. S. K. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa863 · Cited by 16

Large-scale in silico mutagenesis experiments reveal optimization of genetic code and codon usage for protein mutational robustness

Schwersensky, M., Rooman, M. J., & Pucci, F. (2020) · BMC Biology · doi:10.1186/s12915-020-00870-9 · Cited by 16

Insights into the evolutionary forces that shape the codon usage in the viral genome segments encoding intrinsically disordered protein regions

Kumar, N., Kaushik, R., Tennakoon, C., Uversky, V. N., Longhi, S., Zhang, K. Y. J., & Bhatia, S. (2021) · Briefings in Bioinformatics · doi:10.1093/bib/bbab145 · Cited by 16

The whole and its parts: cell-specific functions of brassinosteroids

Aardening, Z., Khandal, H., Erlichman, O. A., & Savaldi‐Goldstein, S. (2024) · Trends in Plant Science · doi:10.1016/j.tplants.2024.10.015 · Cited by 15

Cost-efficiency tradeoff is optimized in various cancer types revealed by genome-wide analysis

Zhao, S., Song, S., Qi, Q., & Wei, L. (2021) · Molecular Genetics and Genomics · doi:10.1007/s00438-020-01747-w · Cited by 15

Possible involvement of silent mutations in cancer pathogenesis and evolution

Kikutake, C., & Suyama, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-34452-w · Cited by 18

Ribosome inactivation regulates translation elongation in neurons

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Acetyl-CoA-dependent ac4C acetylation promotes the osteogenic differentiation of LPS-stimulated BMSCs

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