Cited by 985Estrogen and related hormone effectsReceptor Mechanisms and SignalingAdrenal Hormones and Disorders

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Nongenomic actions of steroid hormones

Lösel, Ralf, Wehling, Martin·2003·Nature Reviews Molecular Cell Biology

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Abstract

Steroid hormones modulate many physiological processes. The effects of steroids that are mediated by the modulation of gene expression are known to occur with a time lag of hours or even days. Research that has been carried out mainly in the past decade has identified other responses to steroids that are much more rapid and take place in seconds or minutes. These responses follow nongenomic pathways, and they are not rare.

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Authors: Lösel, R., & Wehling, M.
Affiliations: Heidelberg University (DE)
Corresponding author: Wehling, Martin
ORCID: Lösel, Ralf
Venue: Nature Reviews Molecular Cell Biology
Publisher: Springer Science and Business Media LLC
Published: 2003-01
Volume: 4
Issue: 1
Pages: 46-55
ISSN: 1471-0072 (ISSN-L)
1471-0080
DOI: 10.1038/nrm1009
OpenAlex: W2029032935
Cited by: 980
References: 124
Citations by year: 2026: 21 · 2025: 17 · 2024: 28 · 2023: 31 · 2022: 36 · 2021: 35 · 2020: 26 · 2019: 32 · 2018: 24 · 2017: 39 · 2016: 34 · 2015: 45 · 2014: 42 · 2013: 36 · 2012: 37
FWCI: 6.04
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Molecular Cell Biology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: non-genomic steroid action, steroid hormones, steroid receptor signaling
MeSH terms: Animals, Cell Communication, Gene Expression Regulation, Humans, Receptors, Steroid, Steroids, Signal Transduction

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Nongenomic actions of steroid hormones

Abstract

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