Cited by 985Estrogen and related hormone effectsReceptor Mechanisms and SignalingAdrenal Hormones and Disorders

The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.

Nongenomic actions of steroid hormones

Lösel, Ralf, Wehling, Martin·2003·Nature Reviews Molecular Cell Biology

Open this paper in CoChat — free account

Abstract

Steroid hormones modulate many physiological processes. The effects of steroids that are mediated by the modulation of gene expression are known to occur with a time lag of hours or even days. Research that has been carried out mainly in the past decade has identified other responses to steroids that are much more rapid and take place in seconds or minutes. These responses follow nongenomic pathways, and they are not rare.

Integrity signals

Registry

Crossref · 10.1038/nrm1009

Cites

124 of 124 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Gene regulation by steroid hormones
Beato, M. (1989) · Cell · doi:10.1016/0092-8674(89)90237-7 · Cited by 3,383
Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
Majewska, M. D., Harrison, N. L., Schwartz, R. D., Barker, J. L., & Paul, S. M. (1986) · Science · doi:10.1126/science.2422758 · Cited by 2,225
Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes
Masui, Y., & Markert, C. L. (1971) · Journal of Experimental Zoology · doi:10.1002/jez.1401770202 · Cited by 1,559
Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen
Chen, Z., Yuhanna, I. S., Galcheva-Gargova, Z., Karas, R. H., Mendelsohn, M. E., & Shaul, P. W. (1999) · Journal of Clinical Investigation · doi:10.1172/jci5347 · Cited by 924
Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells
Pietras, R. J., & Szego, C. M. (1977) · Nature · doi:10.1038/265069a0 · Cited by 697
SPECIFIC, NONGENOMIC ACTIONS OF STEROID HORMONES
Wehling, M. (1997) · Annual Review of Physiology · doi:10.1146/annurev.physiol.59.1.365 · Cited by 663
Self-citation
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase
Hafezi‐Moghadam, A., Simoncini, T., Yang, Z., Limbourg, F. P., Plumier, J.-C., Rebsamen, M. C., Hsieh, C.-M., Chui, D.-S., Thomas, K. L., Prorock, A. J., et al. (2002) · Nature Medicine · doi:10.1038/nm0502-473 · Cited by 596
Progesterone Receptor Contains a Proline-Rich Motif that Directly Interacts with SH3 Domains and Activates c-Src Family Tyrosine Kinases
Boonyaratanakornkit, V., Scott, M. P., Ribon, V., Sherman, L., Anderson, S. M., Maller, J. L., Miller, W. T., & Edwards, D. P. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00304-5 · Cited by 590
Membrane Estrogen Receptor Engagement Activates Endothelial Nitric Oxide Synthase via the PI3-Kinase–Akt Pathway in Human Endothelial Cells
Haynes, M. P., Sinha, D., Russell, K. S., Collinge, M., Fulton, D. J., Morales‐Ruiz, M., Sessa, W. C., & Bender, J. R. (2000) · Circulation Research · doi:10.1161/01.res.87.8.677 · Cited by 576
Nongenomic steroid action: controversies, questions, and answers
LÖSEL, R. M., FALKENSTEIN, E., FEURING, M., SCHULTZ, A., TILLMANN, H.-C., ROSSOL-HASEROTH, K., & WEHLING, M. (2003) · Physiological Reviews · doi:10.1152/physrev.00003.2003 · Cited by 561
Self-citation

Flagged first, then by citations

Show all 124 references

Research works printed but not linked: 1

Klein, K. & Henk, W. Klinisch-experimentelle Untersuchungen über den Einfluβ von Aldosteron auf Hämodynamik und Gerinnung. Z. Kreisl. Forsch. 52, 40–53 (1963).

Sorted by citations

Items 201–300 of 985

Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly?
Gekle, M., & Großmann, C. (2008) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-008-0616-0 · Cited by 80
Magnetic Resonance Neurography–Guided Nerve Blocks for the Diagnosis and Treatment of Chronic Pelvic Pain Syndrome
Fritz, J. M., Chhabra, A. B., Wang, K. C., & Carrino, J. A. (2013) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2013.03.028 · Cited by 77
Mechanisms of action of agrochemicals acting as endocrine disrupting chemicals
Warner, G. R., Mourikes, V. E., Neff, A. M., Brehm, E., & Flaws, J. A. (2019) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2019.110680 · Cited by 76
Immune sexual dimorphism: Effect of gonadal steroids on the expression of cytokines, sex steroid receptors, and lymphocyte proliferation
León-Nava, M. A. D., Castro, K. E. N., Soldevila, G., López-Griego, L., Chávez-Ríos, J. R., Vargas-Villavicencio, J. A., & Morales‐Montor, J. (2008) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2008.11.003 · Cited by 75
Thyroid hormone receptor TRβ1 mediates Akt activation by T3 in pancreatic β cells
Falzacappa, C. V., Petrucci, E., Patriarca, V., Michienzi, S., Stigliano, A., Brunetti, E., Toscano, V., & Misiti, S. (2006) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.02166 · Cited by 74
Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor
Wang, D., Zhang, H., Lang, F. J. W., & Yun, C. C. (2006) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00345.2006 · Cited by 71
Hepatocellular carcinoma and vitamin D: A review
Chiang, K., Yeh, C., Chen, M., & Chen, T. C. (2011) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.06892.x · Cited by 74
17Beta-Estradiol Enhances Leptin Expression in Human Placental Cells Through Genomic and Nongenomic Actions1
Gambino, Y. P., Maymó, J. L., Pérez‐Pérez, A., Dueñas, J. L., Sánchez‐Margalet, V., Calvo, J. C., & Varone, C. L. (2010) · Biology of Reproduction · doi:10.1095/biolreprod.110.083535 · Cited by 74
Increased severity of chemically induced seizures in mice with partially deleted Vitamin D receptor gene
Kalueff, A. V., Minasyan, A., Keisala, T., Kuuslahti, M., Miettinen, S., & Tuohimaa, P. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.10.007 · Cited by 74
Differential Ligand Binding Affinities of Human Estrogen Receptor-α Isoforms
Lin, A. H. Y., Li, R. W. S., Ho, E. Y. W., Leung, G., Leung, S. W. S., Vanhoutte, P. M., & Man, R. Y. K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063199 · Cited by 74
Nuclear receptors and other nuclear transcription factors in mitochondria: Regulatory molecules in a new environment
Psarra, A. G., & Sekeris, C. E. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2007.10.021 · Cited by 74
Evolutionary origins of the estrogen signaling system: Insights from amphioxus
Callard, G. V., Tarrant, A. M., Novillo, A., Yacci, P., Ciaccia, L., Vajda, S., Chuang, G., Kozakov, D., Greytak, S. R., Sawyer, S. J., et al. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2011.03.022 · Cited by 74
Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach
Lucas, S., Heim, R., Negri, M., Antes, I., Ries, C., Schewe, K. E., Bisi, A., Gobbi, S., & Hartmann, R. W. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm800683c · Cited by 73
ent-Steroids: Novel tools for studies of signaling pathways
Covey, D. F. (2008) · Steroids · doi:10.1016/j.steroids.2008.11.019 · Cited by 74
Vitamin D Signaling in Myogenesis: Potential for Treatment of Sarcopenia
Wagatsuma, A., & Sakuma, K. (2014) · BioMed Research International · doi:10.1155/2014/121254 · Cited by 73
Opposing effects of estradiol- and testosterone-membrane binding sites on T47D breast cancer cell apoptosis
Kampa, M., Nifli, A., Charalampopoulos, I., Alexaki, V. I., Theodoropoulos, P. A., Stathopoulos, E. N., Gravanis, A., & Castanas, E. (2005) · Experimental Cell Research · doi:10.1016/j.yexcr.2005.02.027 · Cited by 72
Cross-talk between aldosterone and angiotensin signaling in vascular smooth muscle cells
Rautureau, Y., Paradis, P., & Schiffrin, E. L. (2011) · Steroids · doi:10.1016/j.steroids.2011.02.015 · Cited by 79
Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells
Papadopoulou, N., Charalampopoulos, I., Alevizopoulos, K., Gravanis, A., & Stournaras, C. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.07.012 · Cited by 71
Glucocorticoids stimulate cation absorption by semicircular canal duct epithelium via epithelial sodium channel
Pondugula, S. R., Sanneman, J. D., Wangemann, P., Milhaud, P. G., & Marcus, D. C. (2004) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00387.2003 · Cited by 71
Fine-Tuning the Selectivity of Aldosterone Synthase Inhibitors: Structure−Activity and Structure−Selectivity Insights from Studies of Heteroaryl Substituted 1,2,5,6-Tetrahydropyrrolo[3,2,1-ij]quinolin-4-one Derivatives
Lucas, S., Negri, M., Heim, R., Zimmer, C., & Hartmann, R. W. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm101470k · Cited by 71
Minireview: Epigenomic Plasticity and Vulnerability to EDC Exposures
Walker, C. L. (2016) · Molecular Endocrinology · doi:10.1210/me.2016-1086 · Cited by 76
Glucocorticoids inhibit degranulation of mast cells in allergic asthma via nongenomic mechanism
Zhou, J., Liu, D., Liu, C., Kang, Z. ‐., Shen, X., Chen, Y., Xu, T., & Jiang, C. (2008) · Allergy · doi:10.1111/j.1398-9995.2008.01725.x · Cited by 70
Vertebrate Sex Steroid Receptors: Evolution, Ligands, and Neurodistribution
Guerriero, G. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.04460.x · Cited by 68
Characterization of vitamin D receptor (VDR) in lung adenocarcinoma
Kim, S. H., Chen, G., King, A. N., Jeon, C. K., Christensen, P. J., Zhao, L., Simpson, R. U., Thomas, D. G., Giordano, T. J., Brenner, D. E., et al. (2012) · Lung Cancer · doi:10.1016/j.lungcan.2012.04.010 · Cited by 69
The effect of corticosteroids on the disposal of long-acting β2-agonists by airway smooth muscle cells
Horváth, G., Mendes, E. S., Schmid, N., Schmid, A., Conner, G. E., Salathe, M. A., & Wanner, A. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.08.034 · Cited by 69
Rapid Effects of Estradiol on Aggression in Birds and Mice: The Fast and the Furious: Fig. 1
Heimovics, S. A., Trainor, B. C., & Soma, K. K. (2015) · Integrative and Comparative Biology · doi:10.1093/icb/icv048 · Cited by 69
Steroid hormone receptor signaling in tumorigenesis
Singh, R. R., & Kumar, R. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20566 · Cited by 67
Significance of ER–Src axis in hormonal therapy resistance
Vallabhaneni, S., Nair, B. C., Cortez, V. A., Challa, R., Chakravarty, D., TEKMAL, R. R., & Vadlamudi, R. K. (2010) · Breast Cancer Research and Treatment · doi:10.1007/s10549-010-1312-2 · Cited by 68
Progesterone receptors: various forms and functions in reproductive tissues
Sushama, G.-S. (2005) · Frontiers in bioscience · doi:10.2741/1685 · Cited by 68
Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors
Finn, D. A., Beckley, E. H., Kaufman, K. R., & Ford, M. M. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.07.002 · Cited by 68
G-protein-coupled glucocorticoid receptors on the pituitary cell membrane
Maier, C., Rünzler, D., Schindelar, J., Grabner, G., Waldhäusl, W. K., Köhler, G., & Luger, A. (2005) · Journal of Cell Science · doi:10.1242/jcs.02462 · Cited by 68
Interaction between corticosteroids and muscarinic antagonists in human airways
Cazzola, M., Calzetta, L., Rogliani, P., Puxeddu, E., Facciolo, F., & Matera, M. G. (2015) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2015.11.004 · Cited by 66
Glucocorticoid Receptor Counteracts Tumorigenic Activity of Akt in Skin through Interference with the Phosphatidylinositol 3-Kinase Signaling Pathway
Leis, H., Page, A., Ramı́rez, Á., Bravo, A., Segrelles, C., Paramio, J. M., Barettino, D., Jorcano, J. L., & Pérez, P. (2003) · Molecular Endocrinology · doi:10.1210/me.2003-0350 · Cited by 66
A Role for Estrogen Receptor alpha36 in Cancer Progression
Pagano, M., Ortona, E., & Dupuis, M. L. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00506 · Cited by 65
Cis‐isomerism and other chemical requirements of steroidal agonists and partial agonists acting at TRPM3 channels
Majeed, Y., Agarwal, A., Naylor, J., Seymour, V., Jiang, S., Muraki, K., Fishwick, C. W. G., & Beech, D. J. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.00892.x · Cited by 63
The epithelial sodium channel (ENaC): Mediator of the aldosterone response in the vascular endothelium?
Kusche‐Vihrog, K., Callies, C., Fels, J. J., & Oberleithner, H. (2009) · Steroids · doi:10.1016/j.steroids.2009.09.003 · Cited by 63
Progestin Activation of Nongenomic Pathways via Cross Talk of Progesterone Receptor with Estrogen Receptor β Induces Proliferation of Endometrial Stromal Cells
Vallejo, G., Ballaré, C., Barañao, J. L., Beato, M., & Saragüeta, P. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0016 · Cited by 64
Corticosteroids for Multiple Sclerosis: I. Application for Treating Exacerbations
Frohman, E. M., Shah, A., Eggenberger, E., Metz, L. M., Zivadinov, R., & Stüve, O. (2007) · Neurotherapeutics · doi:10.1016/j.nurt.2007.07.008 · Cited by 64
Vitamin D for the prevention and treatment of pancreatic cancer
Chiang, K., & Chen, T. C. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.3349 · Cited by 64
Mechanisms of glucocorticoid action and insensitivity in airways disease
Boardman, C., Chachi, L., Gavrila, A., Keenan, C. R., Perry, M. M., Xia, Y., Meurs, H., & Sharma, P. K. (2014) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2014.08.008 · Cited by 69
Membrane progesterone receptor gamma: Tissue distribution and expression in ciliated cells in the fallopian tube
Nutu, M., Weijdegård, B., Thomas, P., Bergh, C., Thurin‐Kjellberg, A., Pang, Y., Billig, H., & Larsson, D. G. J. (2006) · Molecular Reproduction and Development · doi:10.1002/mrd.20685 · Cited by 63
Corticosteroids and Redox Potential Modulate Spontaneous Contractions in Isolated Rat Ventricular Cardiomyocytes
Rossier, M. F., Lenglet, S., Vetterli, L., Python, M., & Maturana, A. D. (2008) · Hypertension · doi:10.1161/hypertensionaha.108.114223 · Cited by 66
The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery
Santoro, A., Mele, E., Marino, M., Viggiano, A., Nori, S. L., & Meccariello, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020972 · Cited by 63
Activation of membrane estrogen receptors induce pro-survival kinases
Alexaki, V. I., Charalampopoulos, I., Kampa, M., Nifli, A., Hatzoglou, A., Gravanis, A., & Castanas, E. (2006) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2005.08.017 · Cited by 62
Thiazolidinediones Enhance Sodium-Coupled Bicarbonate Absorption from Renal Proximal Tubules via PPARγ-Dependent Nongenomic Signaling
Endo, Y., Suzuki, M., Yamada, H., Horita, S., Kunimi, M., Yamazaki, O., Shirai, A., Nakamura, M., Iso-O, N., Li, Y., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.02.015 · Cited by 62
Peroxisome Proliferator-Activated Receptor-α Contributes to the Anti-Inflammatory Activity of Glucocorticoids
Cuzzocrea, S., Bruscoli, S., Mazzon, E., Crisafulli, C., Donato, V., Paola, R. D., Velardi, E., Esposito, E., Nocentini, G., & Riccardi, C. (2007) · Molecular Pharmacology · doi:10.1124/mol.107.041475 · Cited by 60
Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor–positive human breast cancer cells
Herynk, M. H., Beyer, A. R., Cui, Y., Weiss, H. L., Anderson, E., Green, T. P., & Fuqua, S. A. W. (2006) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0394 · Cited by 61
Vascular mechanisms of testosterone: The non-genomic point of view
Lorigo, M., Mariana, M., Lemos, M. C., & Cairrão, E. (2019) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2019.105496 · Cited by 61
Signal transduction mechanisms mediating rapid, nongenomic effects of cortisol on prolactin release
Borski, R. J., Hyde, G. N., & Fruchtman, S. (2002) · Steroids · doi:10.1016/s0039-128x(01)00197-0 · Cited by 61
Estrogen in the Limbic System
Horst, G. J. T. (2010) · Vitamins and hormones · doi:10.1016/s0083-6729(10)82017-5 · Cited by 62
Cellular Distribution of the GABAA Receptor‐Modulating 3α‐Hydroxy, 5α‐Reduced Pregnane Steroids in the Adult Rat Brain
Saalmann, Y. B., Kirkcaldie, M., Waldron, S., & Calford, M. B. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01527.x · Cited by 61
Synthetic Androgens as Designer Supplements
Joseph, J. F., & Parr, M. K. (2014) · Current Neuropharmacology · doi:10.2174/1570159x13666141210224756 · Cited by 60
Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line
McEneaney, V., Harvey, B. J., & Thomas, W. (2007) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2007.03.043 · Cited by 61
Activation of progestin receptors in female reproductive behavior: Interactions with neurotransmitters
Mani, S. K., & Portillo, W. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.01.002 · Cited by 59
Vitamin D ameliorates high-fat-diet-induced hepatic injury via inhibiting pyroptosis and alters gut microbiota in rats
Zhang, X., Shang, X., Jin, S. K., Ma, Z., Wang, H., Ao, N., Yang, J., & Jian, D. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2021.108894 · Cited by 60
Nongenomic action of an insect steroid hormone in steroid-induced programmed cell death
Iga, M., Iwami, M., & Sakurai, S. (2006) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2006.08.005 · Cited by 59
The mineralocorticoid receptor agonist, fludrocortisone, inhibits pituitary-adrenal activity in humans after pre-treatment with metyrapone
Otte, C., Jahn, H., Yassouridis, A., Arlt, J., Stober, N., Maass, P., Wiedemann, K., & Kellner, M. B. (2003) · Life Sciences · doi:10.1016/s0024-3205(03)00513-7 · Cited by 59
Estrogen Receptor Alpha Interacts with Mitochondrial Protein HADHB and Affects Beta-Oxidation Activity
Zhou, Z., Zhou, J., & Du, Y. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m111.011056 · Cited by 59
Molecular characterization of three forms of putative membrane-bound progestin receptors and their tissue-distribution in channel catfish, Ictalurus punctatus
Kazeto, Y., Goto-Kazeto, R., Thomas, P., & Trant, J. M. (2005) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.01721 · Cited by 59
Thombospondin-1 Disrupts Estrogen-Induced Endothelial Cell Proliferation and Migration and Its Expression Is Suppressed by Estradiol
Sengupta, K., Banerjee, S., Saxena, N. K., & Banerjee, S. K. (2004) · Molecular Cancer Research · doi:10.1158/1541-7786.150.2.3 · Cited by 59
Glucocorticoid Receptor Is Required for Skin Barrier Competence
Bayo, P., Sanchís, A., Bravo, A., Cascallana, J. L., Buder, K., Tuckermann, J. P., Schütz, G., & Pérez, P. (2007) · Endocrinology · doi:10.1210/en.2007-0814 · Cited by 58
Nongenomic Actions of Androgen in Sertoli Cells
Walker, W. H. (2003) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(03)01006-8 · Cited by 59
Specific nongenomic actions of aldosterone
Falkenstein, E., Christ, M., Feuring, M., & Wehling, M. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00980.x · Cited by 58
Self-citation
Coexistence of Intracellular and Membrane-Bound Progesterone Receptors in Human Testis
Shah, C., Modi, D. N., Sachdeva, G., Gadkar, S., & Puri, C. P. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0793 · Cited by 58
Expression of Estrogen Receptor-α and -β, Glucocorticoid Receptor, and Progesterone Receptor Genes in Human Embryonic Stem Cells and Embryoid Bodies
Hong, S. H., Nah, H. Y., Lee, Y. J., Lee, J. W., Park, J. H., Kim, S. J., Lee, J. B., Yoon, H. S., & Kim, C. H. (2004) · Molecules and Cells · doi:10.1016/s1016-8478(23)13119-0 · Cited by 58
Presence of membrane ecdysone receptor in the anterior silk gland of the silkworm Bombyx mori
Elmogy, M., Iwami, M., & Sakurai, S. (2004) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.2004.04249.x · Cited by 57
Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+exchanger NHE3 by glucocorticoids
He, P., Lee, S., Lin, S., Seidler, U. E., Lang, F. J. W., Fejes‐Tóth, G., Náray‐Fejes‐Tóth, A., & Yun, C. C. (2011) · Molecular Biology of the Cell · doi:10.1091/mbc.e11-04-0328 · Cited by 55
Glucocorticoid actions on airway epithelial responses in immunity: Functional outcomes and molecular targets
Stellato, C. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.10.041 · Cited by 58
Analysis of estrogen-regulated genes in mouse uterus using cDNA microarray and laser capture microdissection
Hong, S., Nah, H. Y., Lee, J. Y., Gye, M. C., Kim, C. H., & Kim, M. K. (2004) · Journal of Endocrinology · doi:10.1677/joe.0.1810157 · Cited by 57
Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects
Shaqura, M. A., Li, X., Al‐Khrasani, M., Shakibaei, M., Tafelski, S., Fürst, S., Beyer, A., Kawata, M., Schäfer, M., & Mousa, S. A. (2016) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.08.019 · Cited by 57
Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E2 release
Chivers, J. E., Cambridge, L. M., Catley, M. C., Mak, J., Donnelly, L., Barnes, P. J., & Newton, R. C. (2004) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.2004.04342.x · Cited by 58
Deciphering the proteomic signature of human endometrial receptivity
Garrido‐Gómez, T., Quiñonero, A., Antúnez, O., Díaz-Gimeno, P., Bellver, J., Simón, C., & Domı́nguez, F. (2014) · Human Reproduction · doi:10.1093/humrep/deu171 · Cited by 56
Transcriptomic and Network Analyses Reveal Mechanistic-Based Biomarkers of Endocrine Disruption in the Marine Mussel, Mytilus edulis
Blalock, B. J., Robinson, W. E., Loguinov, A. V., Vulpe, C. D., Krick, K. S., & Poynton, H. C. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.8b01604 · Cited by 56
Honey, we need to talk about the membrane progestin receptors
Fernandes, M. S., Brosens, J. J., & Gellersen, B. (2008) · Steroids · doi:10.1016/j.steroids.2007.12.004 · Cited by 56
Brief exposure to exogenous testosterone increases death signaling and adversely affects myocardial function after ischemia
Crisostomo, P. R., Wang, M., Wairiuko, G. M., Morrell, E. D., & Meldrum, D. R. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00833.2005 · Cited by 56
Specific Non-Genomic, Membrane-Localized Binding Sites for Progesterone in the Bovine Corpus Luteum1
Rae, M. T., Menzies, G. S., McNeilly, A. S., Woad, K. J., WEBB, R., & Bramley, T. A. (1998) · Biology of Reproduction · doi:10.1095/biolreprod58.6.1394 · Cited by 56
Minireview: Role of Kinases and Chromatin Remodeling in Progesterone Signaling to Chromatin
Vicent, G. P., Nacht, A. S., Zaurín, R., Ballaré, C., Clausell, J., & Beato, M. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0027 · Cited by 55
Src kinase-mediates androgen receptor-dependent non-genomic activation of signaling cascade leading to endothelial nitric oxide synthase
Yu, J., Akishita, M., Eto, M., Koizumi, H., Hashimoto, R., Ogawa, S., Tanaka, K., Ouchi, Y., & Okabe, T. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.06.151 · Cited by 55
Estrogens and Prostate Cancer: Etiology, Mediators, Prevention, and Management
Ho, S., Lee, M., Lam, H., & Leung, Y. (2011) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2011.05.002 · Cited by 55
The importance of non-nuclear AR signaling in prostate cancer progression and therapeutic resistance
Zarif, J. C., & Miranti, C. K. (2016) · Cellular Signalling · doi:10.1016/j.cellsig.2016.01.013 · Cited by 59
Novel estrogen receptor coactivator PELP1/MNAR gene and ERβ expression in salivary duct adenocarcinoma: potential therapeutic targets
Vadlamudi, R. K., Balasenthil, S., Şahin, A. A., Kies, M. S., Weber, R. S., Kumar, R., & El‐Naggar, A. K. (2005) · Human Pathology · doi:10.1016/j.humpath.2005.03.016 · Cited by 55
Modulation of nicotinic acetylcholine receptor function through the outer and middle rings of transmembrane domains.
Barrantes, F. J. (2003) · PubMed · Cited by 55
Nongenomic effects of aldosterone: cellular aspects and clinical implications
Lösel, R., Feuring, M., Falkenstein, E., & Wehling, M. (2002) · Steroids · doi:10.1016/s0039-128x(01)00176-3 · Cited by 55
Self-citation
Extranuclear estrogen receptor's roles in physiology: lessons from mouse models
Levin, E. R. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00626.2013 · Cited by 54
Brassinosteroids roles and applications: an up-date
Coll, Y., Coll, F., Amorós, A., & Pujol, M. (2015) · Biologia · doi:10.1515/biolog-2015-0085 · Cited by 55
Estrogen induces phospholipase A2 activation through ERK1/2 to mobilize intracellular calcium in MCF-7 cells
Thomas, W., Coen, N., Faherty, S., Flatharta, C. Ó., & Harvey, B. J. (2005) · Steroids · doi:10.1016/j.steroids.2005.10.010 · Cited by 54
Estrogen receptor beta as epigenetic mediator of miR-10b and miR-145 in mammary cancer
Piperigkou, Z., Franchi, M., Götte, M., & Karamanos, N. K. (2017) · Matrix Biology · doi:10.1016/j.matbio.2017.08.002 · Cited by 55
RETRACTED ARTICLE: Regulation of estrogen receptor signaling in breast carcinogenesis and breast cancer therapy
Zhou, Z., Qiao, J. X., Shetty, A., Wu, G. Y., Huang, Y., Davidson, N. E., & Wan, Y. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1376-3 · Cited by 52
Retracted
Integrating signals between cAMP and MAPK pathways in breast cancer
Castoria, G. (2007) · Frontiers in bioscience · doi:10.2741/2764 · Cited by 52
Aldosterone stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C-dependent pathway
Winter, C., Kampik, N. B., Vedovelli, L., Rothenberger, F., Păunescu, T. G., Stehberger, P. A., Brown, D., John, H., & Wagner, C. A. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00076.2011 · Cited by 52
Colocalization of mineralocorticoid and EGF receptor at the plasma membrane
Großmann, C., Husse, B., Mildenberger, S., Schreier, B., Schumann, K., & Gekle, M. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2010.02.008 · Cited by 52
Steroid Hormone Receptors: Links With Cell Cycle Machinery and Breast Cancer Progression
Saha, S., Dey, S., & Nath, S. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.620214 · Cited by 52
Presence of a Truncated Form of the Vitamin D Receptor (VDR) in a Strain of VDR-Knockout Mice
Bula, C. M., Huhtakangas, J. A., Olivera, C. J., Bishop, J. E., Norman, A. W., & Henry, H. L. (2005) · Endocrinology · doi:10.1210/en.2005-0806 · Cited by 52
Role of Nongenomic Activation of Phosphatidylinositol 3-Kinase/Akt and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase/Extracellular Signal-Regulated Kinase 1/2 Pathways in 1,25D3-Mediated Apoptosis in Squamous Cell Carcinoma Cells
Ma, Y., Yu, W., Kong, R.-X., Trump, D. L., & Johnson, C. S. (2006) · Cancer Research · doi:10.1158/0008-5472.can-06-1333 · Cited by 52
HormoneBase, a population-level database of steroid hormone levels across vertebrates
Vitousek, M. N., Johnson, M. A., Donald, J. W., Francis, C. D., Fuxjager, M. J., Goymann, W., Hau, M., Husak, J. F., Kircher, B. K., Knapp, R., et al. (2018) · Scientific Data · doi:10.1038/sdata.2018.97 · Cited by 51
Glucocorticoids Increase NPY Gene Expression via Hypothalamic AMPK Signaling in Broiler Chicks
Liu, L., Song, Z., Jiao, H., & Lin, H. (2014) · Endocrinology · doi:10.1210/en.2013-1632 · Cited by 51
Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down
Costa, J. L., Eijk, P. P., van de Wiel, M. A., ten Berge, D., Schmitt, F. C., Narvaez, C. J., Welsh, J., & Ylstra, B. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-499 · Cited by 51
Transcriptional signatures of steroid hormones in the striatal neurons and astrocytes
Piechota, M., Korostyński, M., Gołda, S., Ficek, J., Jantas, D., Ziółkowska, B., & Przewłocki, R. (2017) · BMC Neuroscience · doi:10.1186/s12868-017-0352-5 · Cited by 52
Pgrmc1 Knockout Impairs Oocyte Maturation in Zebrafish
Wu, X.-J., Thomas, P., & Zhu, Y. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00560 · Cited by 51
Rapid inhibitory effect of glucocorticoids on airway smooth muscle contractions in guinea pigs
Sun, H., Miao, C., Liu, L., Zhou, J., Su, D.-F., Wang, Y., & Jiang, C. (2005) · Steroids · doi:10.1016/j.steroids.2005.09.019 · Cited by 51

Authors: Lösel, R., & Wehling, M.
Affiliations: Heidelberg University (DE)
Corresponding author: Wehling, Martin
ORCID: Lösel, Ralf
Venue: Nature Reviews Molecular Cell Biology
Publisher: Springer Science and Business Media LLC
Published: 2003-01
Volume: 4
Issue: 1
Pages: 46-55
ISSN: 1471-0072 (ISSN-L)
1471-0080
DOI: 10.1038/nrm1009
OpenAlex: W2029032935
Cited by: 980
References: 124
Citations by year: 2026: 21 · 2025: 17 · 2024: 28 · 2023: 31 · 2022: 36 · 2021: 35 · 2020: 26 · 2019: 32 · 2018: 24 · 2017: 39 · 2016: 34 · 2015: 45 · 2014: 42 · 2013: 36 · 2012: 37
FWCI: 6.04
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Molecular Cell Biology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: non-genomic steroid action, steroid hormones, steroid receptor signaling
MeSH terms: Animals, Cell Communication, Gene Expression Regulation, Humans, Receptors, Steroid, Steroids, Signal Transduction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Nongenomic actions of steroid hormones

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks