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Nongenomic actions of steroid hormones
Abstract
Steroid hormones modulate many physiological processes. The effects of steroids that are mediated by the modulation of gene expression are known to occur with a time lag of hours or even days. Research that has been carried out mainly in the past decade has identified other responses to steroids that are much more rapid and take place in seconds or minutes. These responses follow nongenomic pathways, and they are not rare.
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“In plants, brassinosteroids play an essential role in plant growth and development (4–7), as well as thermotolerance (30).”
From Anabolic effect of plant brassinosteroid (2011) · cites this paper as [5]
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“Previous studies indicated that animal steroid hormones can trigger nongenomic actions through the cytoplasmic membrane [10].”
From G-protein-coupled receptor participates in 20-hydroxyecdysone signaling on the plasma membrane (2014) · cites this paper as [10]
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Metadata
- Authors
- Lösel, R., & Wehling, M.
- Affiliations
- Heidelberg University (DE)
- Corresponding author
- Wehling, Martin
- ORCID
- Lösel, Ralf
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2003-01
- Volume
- 4
- Issue
- 1
- Pages
- 46-55
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2029032935
- Cited by
- 980
- References
- 124
- Citations by year
- 2026: 21 · 2025: 17 · 2024: 28 · 2023: 31 · 2022: 36 · 2021: 35 · 2020: 26 · 2019: 32 · 2018: 24 · 2017: 39 · 2016: 34 · 2015: 45 · 2014: 42 · 2013: 36 · 2012: 37
- FWCI
- 6.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Molecular Cell Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- non-genomic steroid action, steroid hormones, steroid receptor signaling
- MeSH terms
- Animals, Cell Communication, Gene Expression Regulation, Humans, Receptors, Steroid, Steroids, Signal Transduction
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