Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

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2. Airborne Nanoplastics Exposure Inducing Irreversible Glucose Increase and Complete Hepatic Insulin Resistance
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3. Omentina: papel en la resistencia a la insulina, inflamación y protección cardiovascular
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4. Isoflurane aggravates peripheral and central insulin resistance in high-fat diet/streptozocin-induced type 2 diabetic mice
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5. High sucrose diet induces morphological, structural and functional impairments in the renal tubules of Drosophila melanogaster: A model for studying type-2 diabetes mediated renal tubular dysfunction
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7. Role of mitochondria-associated endoplasmic reticulum membranes in insulin sensitivity, energy metabolism, and contraction of skeletal muscle
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8. Effects of Combined Dietary Chromium(III) Propionate Complex and Thiamine Supplementation on Insulin Sensitivity, Blood Biochemical Indices, and Mineral Levels in High-Fructose-Fed Rats
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9. Control of Voltage-gated Potassium Channel Kv2.2 Expression by Pyruvate-Isocitrate Cycling Regulates Glucose-stimulated Insulin Secretion*
   M. Jensen, Jonathan M. Haldeman, Heng-Tao Zhang, Dan-Hong Lu, M. Huising, W. Vale, H. Hohmeier, Paul A. Rosenberg, C. Newgard · 2013 · Journal of Biological Chemistry
10. Insulin receptor isoform A confers a higher proliferative capability to pancreatic beta cells enabling glucose availability and IGF-I signaling
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11. T2D@ZJU: a knowledgebase integrating heterogeneous connections associated with type 2 diabetes mellitus
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12. Mammalian Target of Rapamycin at the Crossroad Between Alzheimer’s Disease and Diabetes
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13. The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk.
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14. Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure
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15. Palmitate Enhances Protein Tyrosine Phosphatase 1B (PTP1B) Gene Expression at Transcriptional Level in C2C12 Skeletal Muscle Cells
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16. Machine Learning in Biology and Medicine
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17. NGBR Is Required to Ameliorate Type 2 Diabetes in Mice by Enhancing Insulin Sensitivity
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18. Insulin release, peripheral insulin resistance and muscle function in protein malnutrition: a role of tricarboxylic acid cycle anaplerosis
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19. Lupinus mutabilis Extract Exerts an Anti-Diabetic Effect by Improving Insulin Release in Type 2 Diabetic Goto-Kakizaki Rats
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20. Sirtuin 5 overexpression attenuates glucolipotoxicity-induced pancreatic β cells apoptosis and dysfunction
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21. Glucose-mediated tyrosine nitration in adipocytes: Targets and consequences
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22. Cholesterol in Pancreatic β-Cell Death and Dysfunction
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23. The Impact of Current and Novel anti-diabetic Therapies On Cardiovascular Risk
    John R. Ussher, Gopinath Sutendra, Jagdip S. Jaswal · 2012 · Future Cardiology
24. Anti-IAPP Monoclonal Antibody Improves Clinical Symptoms in a Mouse Model of Type 2 Diabetes
    Anne‐Cathrine S. Vogt, Elisa S. Roesti, Mona Omar Mohsen, Ainars Leonchiks, Monique Vogel, Martin F. Bachmann · 2021 · Vaccines
25. Energy transfer between the mitochondrial network and lipid droplets in insulin resistant skeletal muscle
    Hailey A. Parry, Brian C. Glancy · 2021 · Current Opinion in Physiology
26. Comprehensive interrogation of human skeletal muscle reveals a dissociation between insulin resistance and mitochondrial capacity
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27. Role of Transcription Factor Modifications in the Pathogenesis of Insulin Resistance
    Miyoung Kim, Jin-Sik Bae, Tae Hyun Kim, Joo-Man Park, Yong‐Ho Ahn · 2011 · Experimental Diabetes Research
28. Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes
    Jill E. Skepner, Lorraine D. Shelly, Chengjie Ji, Benjamin Reidich, Yi Luo · 2010 · Prostaglandins & Other Lipid Mediators
29. Transcriptomic profiles of peripheral white blood cells in type II diabetes and racial differences in expression profiles
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30. Microcystin-LR induces dysfunction of insulin secretion in rat insulinoma (INS-1) cells: Implications for diabetes mellitus
    Yanyan Zhao, Kun� Shi, Xiaomei Su, Liqiang Xie, Yunjun Yan · 2016 · Journal of Hazardous Materials
31. A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation
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32. Telmisartan and esculetin combination ameliorates type 2 diabetic cardiomyopathy by reversal of H3, H2A, and H2B histone modifications
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33. Cognitive deficits and Alzheimer-like neuropathological impairments during adolescence in a rat model of type 2 diabetes mellitus
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34. The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner
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35. Indexing Natural Products for Their Potential Anti-Diabetic Activity: Filtering and Mapping Discriminative Physicochemical Properties
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36. Mitochondrial Targeted Coenzyme Q, Superoxide, and Fuel Selectivity in Endothelial Cells
    Fink, Brian D., O'Malley, Yunxia, Dake, Brian L., Ross, Nicolette C., Prisinzano, Thomas E., Sivitz, William I. · 2009 · PLoS ONE
37. Mitochondrial Biomarkers and Metabolic Syndrome in Bipolar Disorder
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38. Effect of circadian clock disruption on type 2 diabetes
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39. Penipyrols C–G and methyl-penipyrol A, α-pyrone polyketides from the mangrove derived fungus Penicillium sp. HDN-11-131
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40. Associations between persistent organic pollutants and type 1 diabetes in youth
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41. Palmitate-induced changes in energy demand cause reallocation of ATP supply in rat and human skeletal muscle cells.
    R. B. Nisr, C. Affourtit · 2016 · Biochimica et Biophysica Acta
42. Histone deacetylase inhibition regulates miR-449a levels in skeletal muscle cells
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43. Evaluation of Glycemic Control, Lifestyle and Clinical Characteristics in Patients with Type 2 Diabetes Treated at King Abdullah University Hospital in Jordan
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44. The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity
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45. Cardiac Development and Transcription Factors: Insulin Signalling, Insulin Resistance, and Intrauterine Nutritional Programming of Cardiovascular Disease
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46. Clinical and radiographic indices around narrow diameter implants placed in different glycemic‐level patients
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47. GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve
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48. Identification of a small molecule that stimulates human β-cell proliferation and insulin secretion, and protects against cytotoxic stress in rat insulinoma cells
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49. Rule-based multi-scale simulation for drug effect pathway analysis
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50. The Effects of Long‐ or Medium‐Chain Fat Diets on Glucose Tolerance and Myocellular Content of Lipid Intermediates in Rats
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51. Biphasic effect of insulin on beta cell apoptosis depending on glucose deprivation
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52. Insulin receptor isoform A ameliorates long-term glucose intolerance in diabetic mice
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53. Protein malnutrition potentiates the amplifying pathway of insulin secretion in adult obese mice
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54. Staprexanthones, Xanthone-Type Stimulators of Pancreatic β-Cell Proliferation from a Mangrove Endophytic Fungus
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55. Protein Glycosylation in Diabetes
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56. Preparation and Characterization of Auricularia cornea Ehrenb Polysaccharide-Zn Complex and Its Hypoglycemic Activity through Regulating Insulin Resistance in HepG2 Cells
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57. Vitamin B6 rescues insulin resistance and glucose‐induced DNA damage caused by reduced activity of Drosophila PI3K
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58. Butyrylcholinesterase interactions with amylin may protect pancreatic cells in metabolic syndrome
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59. Effect of exercise on lipolysis in adipose tissue
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60. Macrophage Migration Inhibitory Factor and Malondialdehyde as Potential Predictors of Vascular Risk Complications in Type 2 Diabetes Mellitus: Cross-Sectional Case Control Study in Saudi Arabia
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61. Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress
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62. Coordinate Activation of Redox-Dependent ASK1/TGF-β Signaling by a Multiprotein Complex (MPK38, ASK1, SMADs, ZPR9, and TRX) Improves Glucose and Lipid Metabolism in Mice
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63. Hypoglycemic effects and associated mechanisms of resveratrol and related stilbenes in diet
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64. Severe Hepatic Insulin Resistance Induces Vascular Dysfunction: Improvement by Liver-Specific Insulin Receptor Isoform A Gene Therapy in a Murine Diabetic Model
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65. The impact of obesity-associated glycine deficiency on the elimination of endogenous and exogenous metabolites via the glycine conjugation pathway
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66. Lack of GPR40 / FFAR 1 does not induce diabetes even under insulin resistance condition
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67. Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome
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68. Is free triiodothyronine important in the development of insulin resistance in healthy people?
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69. Berberine inhibits glucose oxidation and insulin secretion in rat islets
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70. Sarcopoterium spinosum extract improved insulin sensitivity in mice models of glucose intolerance and diabetes
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71. Nortropane alkaloids as pharmacological chaperones in the rescue of equine adipose-derived mesenchymal stromal stem cells affected by metabolic syndrome through mitochondrial potentiation, endoplasmic reticulum stress mitigation and insulin resistance alleviation
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72. The combined role of allelic variants of IRS-1 and IRS-2 genes in susceptibility to type2 diabetes in the Punjabi Pakistani subjects
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73. Hepatic fatty acid biosynthesis is more responsive to protein than carbohydrate in rainbow trout during acute stimulations
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74. Effect of Ursolic Acid on Insulin Resistance and Hyperinsulinemia in Rats with Diet-Induced Obesity: Role of Adipokines Expression
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75. Islet-on-a-chip for the study of pancreatic β-cell function
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76. Intestinal GATA4 deficiency protects from diet-induced hepatic steatosis
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77. Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice
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78. Hyperaminoacidaemia at postprandial levels does not modulate glucose metabolism in type 2 diabetes mellitus
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79. Alterations in plasma acylcarnitine and amino acid profiles may indicate poor nutrition during the suckling period due to maternal intake of an unbalanced diet and may predict later metabolic dysfunction
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80. Urban environment as an independent predictor of insulin resistance in a South Asian population
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81. The role of α-ketoglutarate and the hypoxia sensing pathway in the regulation of pancreatic β-cell function
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82. Elevated levels of branched‐chain amino acids have little effect on pancreatic islet cells, but l ‐arginine impairs function through activation of the endoplasmic reticulum stress response
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83. Identification of ATP Synthase As a Lipid Peroxide Protein Adduct in Pancreatic Islets From Humans With and Without Type 2 Diabetes Mellitus
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84. Lifestyle risk factors for progesterone-related diabetes mellitus in elkhounds - a case-control study
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85. Methylation of Specific CpG Sites in IL-1β and IL1R1 Genes is Affected by Hyperglycaemia in Type 2 Diabetic Patients
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86. Plant-Derived Bioactive Peptides: Extraction, Isolation, Purification, Pharmacological Activities, Structure–Activity Relationship, and Applications
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87. Genome-wide copy number variation study reveals KCNIP1 as a modulator of insulin secretion
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88. Concerted regulation of non-alcoholic fatty liver disease progression by microRNAs in apolipoprotein E-deficient mice
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89. Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction
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90. Partners in diabetes epidemic: A global perspective
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91. Magnetic Optical Microarray Imager for Diagnosing Type of Diabetes in Clinical Blood Serum Samples
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92. Lipoprotein (a), the Metabolic Syndrome and Vascular Risk in Angiographied Coronary Patients
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93. Metabolomics applied to islet nutrient sensing mechanisms
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94. Thiamine Ameliorates Diabetes-Induced Inhibition of Pyruvate Dehydrogenase (PDH) in Rat Heart Mitochondria: Investigating the Discrepancy Between PDH Activity and PDH E1α Phosphorylation in Cardiac Fibroblasts Exposed to High Glucose
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95. Black bean protein concentrate ameliorates hepatic steatosis by decreasing lipogenesis and increasing fatty acid oxidation in rats fed a high fat-sucrose diet
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96. Food Deprivation Promotes Oxidative Imbalance in Rat Brain
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97. Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice
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98. Gene networks and pathways for plasma lipid traits via multitissue multiomics systems analysis
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99. Caveolin-1 Is Essential for the Improvement of Insulin Sensitivity through AKT Activation during Glargine Treatment on Diabetic Mice
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100. Regulation of Neuroinflammatory Signaling by PPARγ Agonist in Mouse Model of Diabetes
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