The DOI matches its Crossref record; 142 of the 142 references it cites were found in a registry or an index.
Open chromatin in pluripotency and reprogramming
Open accessAbstract
Pluripotent stem cells can be derived from embryos or induced from adult cells by reprogramming. They are unique among stem cells in that they can give rise to all cell types of the body. Recent findings indicate that a particularly 'open' chromatin state contributes to maintenance of pluripotency. Two principles are emerging: specific factors maintain a globally open chromatin state that is accessible for transcriptional activation; and other chromatin regulators contribute locally to the silencing of lineage-specific genes until differentiation is triggered. These same principles may apply during reacquisition of an open chromatin state upon reprogramming to pluripotency, and during de-differentiation in cancer.
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Highly efficient Cas9-mediated transcriptional programming
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The 3D genome in transcriptional regulation and pluripotency
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Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis
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Metadata
- Authors
- Gaspar-Maia, A., Alajem, A., Meshorer, E., & Ramalho-Santos, M.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2010-12-22
- Volume
- 12
- Issue
- 1
- Pages
- 36-47
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2095491090
- Cited by
- 573
- References
- 142
- FWCI
- 2.03
- Type
- journal article
- Language
- en
- Open access
- green
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- Gaspar-Maia, A., Alajem, A., Meshorer, E., & Ramalho-Santos, M. (2011). Open chromatin in pluripotency and reprogramming. Nature Reviews Molecular Cell Biology. https://doi.org/10.1038/nrm3036
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