Sirtuins as regulators of metabolism and healthspan

Houtkooper, Riekelt H., Pirinen, Eija, Auwerx, Johan·2012·Nature Reviews Molecular Cell Biology

DOI 10.1038/nrm3293

Cited by (1,003)

Items 701–800 of 1,003

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Zuojun Liu, Minxian Qian, Xiaolong Tang, Wenjing Hu, Shimin Sun, Li Guo, Shuju Zhang, Fanbiao Meng, Xinyue Cao, Jie Lena Sun et al. · 2019 · Nature Metabolism
Elevated Glucose and Insulin Levels Decrease DHA Transfer across Human Trophoblasts via SIRT1-Dependent Mechanism
Jay S. Mishra, Hanjie Zhao, Sari Hattis, Sathish Kumar · 2020 · Nutrients
Epigenetics in Liver Fibrosis: Could HDACs be a Therapeutic Target?
Alex Clavería-Cabello, Leticia Colyn, María Arechederra, Jesús Urmán, Carmen Berasain, Matias Antonio Avila, Maite G. Fernández‐Barrena · 2020 · Cells
Role of Chemerin in Cardiovascular Diseases
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Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway
Fayang Zhou, Anqi Wang, Dan Li, Yitao Wang, Ligen Lin · 2018 · Toxicology and Applied Pharmacology
The role of protein acetylation in carcinogenesis and targeted drug discovery
Yang, Jingru, Song, Cong, Zhan, Xianquan · 2022 · Frontiers in Endocrinology
Monounsaturated Fatty Acids: Key Regulators of Cell Viability and Intracellular Signaling in Cancer
Julia S. Scott, Zeyad D. Nassar, Johannes V. Swinnen, Lisa M. Butler · 2022 · Molecular Cancer Research
Identification of novel SIRT2-selective inhibitors using a click chemistry approach
Prima R. Tatum, Hideyuki Sawada, Yosuke Ota, Yukihiro Itoh, Peng Zhan, Naoya Ieda, Hidehiko Nakagawa, Naoki Miyata, Takayoshi Suzuki · 2014 · Bioorganic & Medicinal Chemistry Letters
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Carla Ritagliati, Victoria Lucía Alonso, Romina Manarin, Pamela Cribb, Esteban Carlos Serra · 2015 · PLoS neglected tropical diseases
Lycopene-rich tomato oleoresin modulates plasma adiponectin concentration and mRNA levels of adiponectin, SIRT1, and FoxO1 in adipose tissue of obese rats
RAM Luvizotto, André Ferreira do Nascimento, Natália CM Miranda, X-D Wang, ALA Ferreira · 2015 · Human & Experimental Toxicology
Ecological relevance of energy metabolism: transcriptional responses in energy sensing and expenditure to thermal and osmotic stresses in an intertidal limpet
Yun‐Wei Dong, Shu Jie Zhang · 2015 · Functional Ecology
Mouse Models of NMNAT1-Leber Congenital Amaurosis (LCA9) Recapitulate Key Features of the Human Disease
Scott H. Greenwald, Jeremy R. Charette, Magdalena Maria Staniszewska, Lan Ying Shi, Steve D. M. Brown, Lisa V. Stone, Qin Liu, Wanda L. Hicks, Gayle B. Collin, Michael R. Bowl et al. · 2016 · American Journal Of Pathology
Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance
Zahra Arab Sadeghabadi, Mitra Nourbakhsh, Parvin Pasalar, Solaleh Emamgholipour, Abolfazl Golestani, Bagher A. Larijani, Maryam Razzaghy‐Azar · 2017 · Obesity Research & Clinical Practice
Multi-targeted Effect of Nicotinamide Mononucleotide on Brain Bioenergetic Metabolism
Nina Klimova, Tibor Kristián · 2019 · Neurochemical Research
SIRT7 regulates the nuclear export of NF-κB p65 by deacetylating Ran
Shihab U. Sobuz, Yoshifumi Sato, Tatsuya Yoshizawa, Fazlul Karim, Katsuhiko Ono, Tomohiro Sawa, Yoichi Miyamoto, Masahiro Oka, Kazuya Yamagata · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria
Eisha Shaw, Manasi Talwadekar, Zeenat Rashida, Nitya Mohan, Aishwarya Acharya, Subhash Khatri, Sunil Laxman, Ullas Kolthur‐Seetharam · 2019 · Molecular and Cellular Biology
Gerometabolites: The pseudohypoxic aging side of cancer oncometabolites
Javier Abel Menéndez, Tomás Alarcón, Jorge Joven · 2014 · Cell Cycle
Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage
Jongho Park, Seong Won Lee, Seung Wook Yang, Hee Min Yoo, Jung Mi Park, Min Woo Seong, Seung Hyeun Ka, Kyu Hee Oh, Young Joo Jeon, Chin Ha Chung · 2014 · Nature Communications
SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation
Ganye Zhao, Hui Wang, Chenzhong Xu, Pan Wang, Jun Chen, Pengfeng Wang, Zhaomeng Sun, Yuanyuan Su, Zhao Wang, Limin Han et al. · 2016 · Aging
Exogenous Ketone Bodies as Promising Neuroprotective Agents for Developmental Brain Injury
Thomas Ragnar Wood, Brianna J. Stubbs, Sandra E. Juul · 2018 · Developmental Neuroscience
The Contribution of Histone Crotonylation to Tissue Health and Disease: Focus on Kidney Health
Julio Manuel Martinez-Moreno, Miguel Fontecha‐Barriuso, Diego Martín‐Sánchez, María Dolores Sánchez-Niño, Marta Ruiz‐Ortega, Ana Belen Sanz, Alberto Ortíz · 2020 · Frontiers in Pharmacology
A multi‐level assessment of the bidirectional relationship between aging and the circadian clock
M. Renate Buijink, Stephan H. Michel · 2020 · Journal of Neurochemistry
Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD + and Suppresses Glycolysis, the TCA Cycle, and Cell Growth
Yan Liu, Chengting Luo, Ting Li, Wenhao Zhang, Zhaoyun Zong, Xiaohui Liu, Haiteng Deng · 2021 · Journal of Proteome Research
Targeting cancer epigenetic pathways with small-molecule compounds: Therapeutic efficacy and combination therapies
Yi Wang, Qiang Xie, Huidan Tan, Minru Liao, Shiou Zhu, Lingli Zheng, Haixia Huang, Bo Liu · 2021 · Pharmacological Research
Harnessing Reversed Allosteric Communication: A Novel Strategy for Allosteric Drug Discovery
Jigang Fan, Yaqin Liu, Ren Kong, Duan Ni, Zhengtian Yu, Shaoyong Lu, Jian Zhang · 2021 · Journal of Medicinal Chemistry
Ageing, Age-Related Cardiovascular Risk and the Beneficial Role of Natural Components Intake
Jacek Rysz, Beata Franczyk, Magdalena Rysz-Górzyńska, Anna Gluba-Brzózka · 2021 · International Journal of Molecular Sciences
Metabolic Relationship Between Cancer-Associated Fibroblasts and Cancer Cells
Christos Sazeides, Anne Le · 2021 · Advances in experimental medicine and biology
Epigenetic modifiers of islet function and mass
Dario F. De Jesus, Rohit Kulkarni · 2014 · Trends in Endocrinology and Metabolism
The mitochondrial NAD+ transporter SLC25A51 is a fasting-induced gene affecting SIRT3 functions
Zhiyao Fu, Hyunbae Kim, Paul T. Morse, Mu‐Jie Lu, Maik Hüttemann, Xiaolu A. Cambronne, Kezhong Zhang, Ren Zhang · 2022 · Metabolism
Hyperglycemia‐induced Sirt3 downregulation increases microglial aerobic glycolysis and inflammation in diabetic neuropathic pain pathogenesis
Yongchang Li, Erliang Kong, Ruifeng Ding, Ruitong Chu, Jinfang Lu, Mengqiu Deng, Hua Tong, Mei Yang, Hao‐Wei Wang, Dashuang Chen et al. · 2024 · CNS Neuroscience & Therapeutics
Senescent endothelial cells: a potential target for diabetic retinopathy
Ying-Lu Liao, Yifan Fang, Jiaxing Sun, Guo‐Rui Dou · 2024 · Angiogenesis
Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD+ protects the heart against pressure overload
Masamichi Yano, Hiroshi Akazawa, Toru Oka, Chizuru Yabumoto, Yoko Kudo-Sakamoto, Takehiro Kamo, Yu Shimizu, Hiroki Yagi, Atsuhiko T. Naito, Jong‐Kook Lee et al. · 2015 · Scientific Reports
Quality control systems in cardiac aging
Ellen K. Quarles, Dao‐Fu Dai, Autumn Tocchi, Nathan Basisty, Lemuel Gitari, Peter S. Rabinovitch · 2015 · Ageing Research Reviews
Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6
Stephanie F. MacCallum, Michael J. Groves, John L. James, Karen E. Murray, Virginia C. L. Appleyard, Alan R. Prescott, AA Drbal, Anna Nicolaou, Joan Cunningham, Sally Haydock et al. · 2013 · Scientific Reports
Age-Related Changes in Sirtuin 7 Expression in Calorie-Restricted and Refed Rats
Agata Wrońska, Aleksandra Ławniczak, Piotr Wierzbicki, Zbigniew Kmieć · 2015 · Gerontology
Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion
Tsunehisa Yamamoto, Kayoko Tamaki, Kohsuke Shirakawa, Kentaro Ito, Xiaoxiang Yan, Yoshinori Katsumata, Atsushi Anzai, Tomohiro Matsuhashi, Jin Endo, Takaaki Inaba et al. · 2016 · American Journal of Physiology-Heart and Circulatory Physiology
Sirtuins as modifiers of Parkinson's disease pathology
Bor Luen Tang · 2016 · Journal of Neuroscience Research
SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation
Tanja Kaufmann, Eva Kukolj, Andreas Brachner, Etienne Beltzung, Melania Bruno, Sebastian Kostrhon, Susanne Opravil, Otto Hudecz, Karl Mechtler, Graham Warren et al. · 2016 · Journal of Cell Science
Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome
Lotte Kors, Elena Rampanelli, Geurt Stokman, Loes M. Butter, Ntsiki M. Held, Nike Claessen, Per W. B. Larsen, Joanne Verheij, Coert Jozef Zuurbier, Gerhard Liebisch et al. · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Improved Motor Nerve Regeneration by SIRT1/Hif1a-Mediated Autophagy
David Romeo-Guitart, Tatiana Leiva-Rodríguez, Joaquím Forés, Caty Casas · 2019 · Cells
Targeting Sirtuin 1 signaling pathway by ginsenosides
Tingting Lou, Qingxia Huang, Hang Su, Daqing Zhao, Xiangyan Li · 2020 · Journal of Ethnopharmacology
Endothelial SIRT1 as a Target for the Prevention of Arterial Aging: Promises and Challenges
Musammat Kulsuma Begum, Daniels Konja, Sandeep Singh, Stefan Chłopicki, Yu Wang · 2021 · Journal of Cardiovascular Pharmacology
Plant mitochondrial retrograde signaling: post-translational modifications enter the stage
Markus Hartl, Iris Finkemeier · 2012 · Frontiers in Plant Science
Electroacupuncture Upregulates SIRT1-Dependent PGC-1α Expression in SAMP8 Mice
Weiguo Dong, Wanqing Quo, Feng Wang, Changzheng Li, Yongcai Xie, Xuehua Zheng, Hong Shi · 2015 · Medical Science Monitor
Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity
Joanna A. Ruszkiewicz, Alexander Bürkle, Aswin Mangerich · 2022 · Journal of Biological Chemistry
Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review
Yunchuan Tian, Chunyan Duan, Jiayue Feng, Jie Liao, Yang Yang, Wei Sun · 2022 · The International Journal of Biochemistry & Cell Biology
Epigenetics of hematopoietic stem cell aging and disease
Motohiko Oshima, Atsushi Iwama · 2014 · International Journal of Hematology
5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors
Teng Ai, Daniel J. Wilson, Swati S. More, Jiashu Xie, Liqiang Chen · 2016 · Journal of Medicinal Chemistry
SIRT7 functions in redox homeostasis and cytoskeletal organization during oocyte maturation
Min Gao, Xiaoyan Li, Yongfu He, Longsen Han, Danhong Qiu, Ling Li, Honglin Liu, Jianguo Liu, Ling Gu · 2018 · The FASEB Journal
The emergence of the nicotinamide riboside kinases in the regulation of NAD+ metabolism
Rachel S. Fletcher, Gareth Geoffrey Lavery · 2018 · Journal of Molecular Endocrinology
Seawater Acidification Reduced the Resistance of Crassostrea gigas to Vibrio splendidus Challenge: An Energy Metabolism Perspective
Ruiwen Cao, Yongliang Liu, Qing Wang, Dinglong Yang, Hui Liu, Wen Ran, Yi Qu, Jianmin Zhao · 2018 · Frontiers in Physiology
Associations of sirtuins with clinicopathological parameters and prognosis in non–small cell lung cancer
Jian Gong, Huiyan Wang, Wenwen Lou, Guiye Wang, Hongqun Tao, Huaikai Wen, Yu Shih Liu, Qipeng Xie · 2018 · Cancer Management and Research
SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high‐fat feeding
Long The Nguyen, Hui Chen, Amgad A. Zaky, Carol A. Pollock, Sonia Saad · 2018 · The Journal of Physiology
Regulation of the Human Papillomavirus Life Cycle by DNA Damage Repair Pathways and Epigenetic Factors
Ekaterina Albert, Laimonis A. Laimins · 2020 · Viruses
SIRT2, a direct target of miR‐212‐5p, suppresses the proliferation and metastasis of colorectal cancer cells
Feng Du, Zhijun Li, Guohua Zhang, Shaoyan Si, Dejun Geng, Zhougen Tao, Kunhua Qiu, Silei Liu, Yu Zhou, Yichao Zhang et al. · 2020 · Journal of Cellular and Molecular Medicine
p53-Dependent LincRNA-p21 Protects Against Proliferation and Anti-apoptosis of Vascular Smooth Muscle Cells in Atherosclerosis by Upregulating SIRT7 via MicroRNA-17-5p
Haojie Wang, Fei He, Bing Liang, Yuanhu Jing, Pei Zhang, Weichao Liu, Hui Zhao · 2020 · Journal of Cardiovascular Translational Research
MicroRNA-338-3p as a novel therapeutic target for intervertebral disc degeneration
Hua Jiang, Abu Moro, Jiaqi Wang, Dihua Meng, Xinli Zhan, Di Chen, Qingjun Wei · 2021 · Experimental & Molecular Medicine
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein
Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg et al. · 2022 · PLoS Pathogens
Cryo-EM structure of the human Sirtuin 6–nucleosome complex
Un Seng Chio, Othman Rechiche, Alysia R. Bryll, Jiang Zhu, Erik M. Leith, Jessica L. Feldman, Craig L. Peterson, Song Tan, Jean‐Paul Armache · 2023 · Science Advances
Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney disease
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Metabolism–epigenome crosstalk in physiology and diseases
Shinjiro Hino, Katsuya Nagaoka, Mitsuyoshi Nakao · 2013 · Journal of Human Genetics
Antagonistic crosstalk between SIRT1, PARP-1, and -2 in the regulation of chronic inflammation associated with aging and metabolic diseases
Hun‐Taeg Chung, Yeonsoo Joe · 2014 · Integrative Medicine Research
Pioglitazone attenuates aging-related disorders in aged apolipoprotein E deficient mice
Dan Shen, Hao Li, Rui Zhou, Mengjie Liu, Hong Yu, Dongfang Wu · 2017 · Experimental Gerontology
Chemical editing of macrocyclic natural products and kinetic profiling reveal slow, tight-binding histone deacetylase inhibitors with picomolar affinities
Kitir, Betül, Maolanon, Alex R., Ohm, Ragnhild G., Colaço, Ana R., Fristrup, Peter, Madsen, Andreas S., Olsen, Christian A. · 2017 · Biochemistry
Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase
Sánchez, Begoña, Muñoz-Pinto, Mario F., Cano, Mercedes · 2023 · Expert Reviews in Molecular Medicine
Acetylation in pathogenesis: Revealing emerging mechanisms and therapeutic prospects
Nan Jiang, Wenyong Li, Shuanglin Jiang, Ming Xie, Ran Liu · 2023 · Biomedicine & Pharmacotherapy
Sirtuins in metabolism, stemness and differentiation
Marcelo Correia, Tânia Perestrelo, Ana Sofia Rodrigues, Marcelo F. Ribeiro, Sandro L. Pereira, Maria Inês Sousa, João Ramalho‐Santos · 2016 · Biochimica et Biophysica Acta (BBA) - General Subjects
SIRT7 depletion inhibits cell proliferation, migration, and increases drug sensitivity by activating p38MAPK in breast cancer cells
Kunlin Chen, Lian Li, Fangxiao Yang, Chengmin Li, Yi‐Ru Wang, Gen‐Lin Wang · 2017 · Journal of Cellular Physiology
Protective effects of higenamine combined with [6]-gingerol against doxorubicin-induced mitochondrial dysfunction and toxicity in H9c2 cells and potential mechanisms
Jianxia Wen, Jian Wang, Pengyan Li, Ruilin Wang, Jiabo Wang, Xuelin Zhou, Lu Zhang, Haotian Li, Shizhang Wei, Huadan Cai et al. · 2019 · Biomedicine & Pharmacotherapy
Histone deacetylases as targets in autoimmune and autoinflammatory diseases
Patricia Hamminger, Ramona Rîca, Wilfried Ellmeier · 2020 · Advances in immunology
SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B
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SIRT6 regulates the cigarette smoke-induced signalling in rheumatoid arthritis synovial fibroblasts
Anna Engler, Fabienne Niederer, Kerstin Klein, Renate E. Gay, Diego Kyburz, Giovanni Guido Camici, Steffen Gay, Caroline Ospelt · 2014 · Journal of Molecular Medicine
Sirtuin 1 in osteoarthritis: Perspectives on regulating glucose metabolism
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Sirtuins and the Estrogen Receptor as Regulators of the Mammalian Mitochondrial UPR in Cancer and Aging
Doris Germain · 2016 · Advances in cancer research
NAD Metabolome Analysis in Human Cells Using 1H NMR Spectroscopy
Konstantin A. Shabalin, Kirill Nerinovski, Alexander P. Yakimov, Veronika Kulikova, Maria Svetlova, Ljudmila Solovjeva, Mikhail Khodorkovskiy, Stepan P. Gambaryan, Richard Cunningham, Marie E. Migaud et al. · 2018 · International Journal of Molecular Sciences
Dual Deletion of the Sirtuins SIRT2 and SIRT3 Impacts on Metabolism and Inflammatory Responses of Macrophages and Protects From Endotoxemia
Tytti Heinonen, Eleonora Ciarlo, Ersilia Rigoni, Jean Regina, Didier Le Roy, Thierry Roger · 2019 · Frontiers in Immunology
Peroxisome Proliferator-Activated Receptors as Molecular Links between Caloric Restriction and Circadian Rhythm
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Sirtuin 3 (SIRT3) Pathways in Age-Related Cardiovascular and Neurodegenerative Diseases
Ciprian Nicolae Silaghi, Marius Florin Farcas, Alexandra Marioara Craciun · 2021 · Biomedicines
Investigation of Carboxylic Acid Isosteres and Prodrugs for Inhibition of the Human SIRT5 Lysine Deacylase Enzyme**
Nima Rajabi, Tobias N. Hansen, Alexander L. Nielsen, Huy T. Nguyen, Michael Bæk, Julie E. Bolding, Oskar Ø. Bahlke, Sylvester E. G. Petersen, Christian R. O. Bartling, Kristian Strømgaard et al. · 2022 · Angewandte Chemie International Edition
SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice
Tatsuya Yoshizawa, Yoshifumi Sato, Shihab U. Sobuz, Tomoya Mizumoto, Tomonori Tsuyama, Md. Fazlul Karim, Keishi Miyata, Masayoshi Tasaki, Masaya Yamazaki, Yuichi Kariba et al. · 2022 · Nature Communications
Sirtuins as emerging anti-parasitic targets
Weiping Zheng · 2012 · European Journal of Medicinal Chemistry
SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons
David Romeo-Guitart, Tatiana Leiva-Rodríguez, Maria Espinosa‐Alcantud, Núria Sima, Alejandro Vaquero, Helena Dominguez‐Martín, Diego Ruano, Caty Casas · 2018 · Cell Death and Disease
Regulation of energy metabolism in the growth plate and osteoarthritic chondrocytes
Elena V. Tchetina, Galina A. Markova · 2018 · Rheumatology International
Exploring the therapeutic potential of quercetin: A focus on its sirtuin‐mediated benefits
Anca Ungurianu, Anca Zanfirescu, Denisa Marilena Margina · 2024 · Phytotherapy Research
Ligand and structure-based approaches for the identification of SIRT1 activators
Vivek K. Vyas, Ashutosh Goel, Manjunath D. Ghate, Palak N. Patel · 2015 · Chemico-Biological Interactions
System Model Network for Adipose Tissue Signatures Related to Weight Changes in Response to Calorie Restriction and Subsequent Weight Maintenance
Émilie Montastier, Nathalie Vialaneix, Sylvie Caspar‐Bauguil, P Hlavatý, EVA TVRZICKÁ, Ignacio González, Wim H. M. Saris, Dominique Langin, Marie Kunešová, Nathalie Viguerie · 2015 · PLoS Computational Biology
Short-term administration of GW501516 improves inflammatory state in white adipose tissue and liver damage in high-fructose-fed mice through modulation of the renin-angiotensin system
D’Angelo Carlo Magliano, Aline Penna‐de‐Carvalho, Manuel Vázquez‐Carrera, Carlos Alberto Mandarim‐de‐Lacerda, Márcia Barbosa Águila · 2015 · Endocrine
Identification of novel SIRT3 inhibitor scaffolds by virtual screening
Heikki S. Salo, Tuomo Laitinen, Antti Poso, Elina M. Jarho, Maija K. Lahtela-Kakkonen · 2013 · Bioorganic & Medicinal Chemistry Letters
Emerging role of silent information regulator 1 (SIRT1) in hepatocellular carcinoma: a potential therapeutic target
Yuting Wu, Xiao‐Ming Meng, Cheng Zhi Huang, Jun Li · 2015 · Tumor Biology
Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis
Jung Hwan Yu, Su Jin Song, Ara Kim, Yoon Jeong Choi, Jo Woon Seok, Hyo Jung Kim, Yoo Jeong Lee, Kwan Sik Lee, Jae Woo Kim · 2016 · Scientific Reports
Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding
Janice E. Drew, Andrew J. Farquharson, Graham William Horgan, Lynda M. Williams · 2016 · The Journal of Nutritional Biochemistry
SIRT2 plays a novel role on progesterone, estradiol and testosterone synthesis via PPARs/LXRα pathways in bovine ovarian granular cells
Dejun Xu, Huanshan He, Xiaohan Jiang, Rongmao Hua, Huali Chen, Li Yang, Jianyong Cheng, Jiaxin Duan, Qingwang Li · 2018 · The Journal of Steroid Biochemistry and Molecular Biology
Novel targets for delaying aging: The importance of the liver and advances in drug delivery
Nicholas J. Hunt, Peter McCourt, David George Le Couteur, Victoria Carroll Cogger · 2018 · Advanced Drug Delivery Reviews
Mitochondrial Genetic Disorders: Cell Signaling and Pharmacological Therapies
Fatima Djouadi, Jean Bastin · 2019 · Cells
Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses
Tytti Heinonen, Eleonora Ciarlo, Didier Le Roy, Thierry Roger · 2019 · Frontiers in Immunology
MicroRNAs, DNA damage response and ageing
Maryam Majidinia, Seyed Mostafa Mir, Mohammad Mirza‐Aghazadeh‐Attari, Roghaieh Asghari, Hossein Samadi Kafil, Amin Safa, Ata Mahmoodpoor, Bahman Yousefi · 2020 · Biogerontology
Beyond mitochondria: Alternative energy-producing pathways from all strata of life
Christopher Auger, Roohi Vinaik, Vasu D. Appanna, Marc G. Jeschke · 2021 · Metabolism
Heritable shifts in redox metabolites during mitochondrial quiescence reprogramme progeny metabolism
Helin Hocaoglu, Lei Wang, Mengye Yang, Sibiao Yue, Matthew Sieber · 2021 · Nature Metabolism
Sirtuins as Metabolic Regulators of Immune Cells Phenotype and Function
Lídia Fortuny, Carlos Sebastián · 2021 · Genes
The Protective Effects of Mogroside V Against Neuronal Damages by Attenuating Mitochondrial Dysfunction via Upregulating Sirtuin3
Hanjiang Luo, Caixia Peng, Xiaofeng Xu, Yuntao Peng, Fang Shi, Qinghua Li, Jianghui Dong, Min Chen · 2022 · Molecular Neurobiology