Sirtuins as regulators of metabolism and healthspan

Houtkooper, Riekelt H., Pirinen, Eija, Auwerx, Johan·2012·Nature Reviews Molecular Cell Biology

Cited by (1,003)

Items 401–500 of 1,003

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    Chen, Yung‐Tsung, Lin, Yu‐Chun, Lin, Jin‐Seng, Yang, Ning‐Sun, Chen, Ming‐Ju · 2018 · Molecular Nutrition &amp; Food Research
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    Anne Brunet, Thomas A. Rando · 2017 · Current Opinion in Cell Biology
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    Lempiäinen, J., Finckenberg, P., Mervaala, E. E., Sankari, S., Levijoki, J., Mervaala, E. M. · 2013 · Acta Physiologica
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  11. Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway
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  12. Unique functional roles for class I and class II histone deacetylases in central nervous system development and function
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  13. Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia
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  16. Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism
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  17. The Role of Myocardial Mitochondrial Quality Control in Heart Failure
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  18. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway
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  19. Effect of Resveratrol on Markers of Oxidative Stress and Sirtuin 1 in Elderly Adults with Type 2 Diabetes
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  21. SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context
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  22. Role of Sirtuins in Regulating Pathophysiology of the Heart
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  23. Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases
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  24. Activation and overexpression of Sirt1 attenuates lung fibrosis via P300
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  25. Metabolic Relationship between Cancer-Associated Fibroblasts and Cancer Cells
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  29. Do Sirtuins Promote Mammalian Longevity?: A Critical Review on Its Relevance to the Longevity Effect Induced by Calorie Restriction
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  30. Deletion of sirtuin 6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice
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  31. Arachidonic and oleic acid exert distinct effects on the DNA methylome
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  37. Melatonin ameliorates PM2.5‐induced cardiac perivascular fibrosis through regulating mitochondrial redox homeostasis
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  42. Using mitochondrial sirtuins as drug targets: disease implications and available compounds
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  49. Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response
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    Lehmann, S, Costa, A C, Celardo, I, Loh, S H Y, Martins, L M · 2016 · Cell Death &amp; Disease
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  63. Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation
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  95. Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development
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