The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Roles of galectins in infection
Open accessAbstract
Galectins, which were first characterized in the mid-1970s, were assigned a role in the recognition of endogenous ('self') carbohydrate ligands in embryogenesis, development and immune regulation. Recently, however, galectins have been shown to bind glycans on the surface of potentially pathogenic microorganisms, and function as recognition and effector factors in innate immunity. Some parasites subvert the recognition roles of the vector or host galectins to ensure successful attachment or invasion. This Review discusses the role of galectins in microbial infection, with particular emphasis on adaptations of pathogens to evasion or subversion of host galectin-mediated immune responses.
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Cites
Decoding the Patterns of Self and Nonself by the Innate Immune System
Medzhitov, R., & Janeway, C. A. (2002) · Science · doi:10.1126/science.1068883 · Cited by 2,154
Symbiotic bacteria direct expression of an intestinal bactericidal lectin
Cash, H. L., Whitham, C. V., Behrendt, C. L., & Hooper, L. V. (2006) · Science · doi:10.1126/science.1127119 · Cited by 1,432
An integrated model of the recognition of Candida albicans by the innate immune system
Netea, M. G., Brown, G. D., Kullberg, B. J., & Gow, N. A. R. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1815 · Cited by 946
The winnowing: establishing the squid–vibrio symbiosis.
Nyholm, S. V., & McFall-Ngai, M. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro957 · Cited by 803 · cited 1×
“Lectin–carbohydrate recognition is not only crucial to the establishment of specific mutualistic associations of symbiotic microorganisms with plants, corals and squid, but can also modulate the physiology of either the host or the symbion”
BackgroundInter-kingdom signalling: Communication between bacteria and their hosts
Hughes, D. T., & Sperandio, V. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1836 · Cited by 761
Regulation of Cytokine Receptors by Golgi N-Glycan Processing and Endocytosis
Partridge, E. A., Le Roy, C., Di Guglielmo, G. M., Pawling, J., Cheung, P., Granovsky, M., Nabi, I. R., Wrana, J. L., & Dennis, J. W. (2004) · Science · doi:10.1126/science.1102109 · Cited by 735
Toscano, M. A., Bianco, G. A., Ilarregui, J. M., Croci, D. O., Correale, J., Hernandez, J. D., Zwirner, N. W., Poirier, F., Riley, E. M., Baum, L. G., et al. (2007) · Nature Immunology · doi:10.1038/ni1482 · Cited by 653
Stevens, J., Blixt, O., Glaser, L., Taubenberger, J. K., Palese, P., Paulson, J. C., & Wilson, I. A. (2006) · Journal of Molecular Biology · doi:10.1016/j.jmb.2005.11.002 · Cited by 613
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition
van den Berg, T. K., Honing, H., Franke, N., van Remoortere, A., Schiphorst, W. E. C. M., Liu, F.-T., Deelder, A. M., Cummings, R. D., Hokke, C. H., & van Die, I. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.3.1902 · Cited by 170
Cited by
Multivalent glycoconjugates as anti-pathogenic agents
Bernardi, A., Jiménez-Barbero, J., Casnati, A., De Castro, C., Darbre, T., Fieschi, F., Finne, J., Funken, H., Jaeger, K.-E., Lahmann, M., et al. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35408j · Cited by 537
Innate immune lectins kill bacteria expressing blood group antigen
Stowell, S. R., Arthur, C. M., Dias-Baruffi, M., Rodrigues, L. C., Gourdine, J.-P., Heimburg-Molinaro, J., Ju, T., Molinaro, R. J., Rivera-Marrero, C., Xia, B., et al. (2010) · Nature Medicine · doi:10.1038/nm.2103 · Cited by 324
Nanoclustering as a dominant feature of plasma membrane organization
Garcia-Parajo, M. F., Cambi, A., Torreno-Pina, J. A., Thompson, N., & Jacobson, K. (2014) · Journal of Cell Science · doi:10.1242/jcs.146340 · Cited by 284
When Galectins Recognize Glycans: From Biochemistry to Physiology and Back Again
Di Lella, S., Sundblad, V., Cerliani, J. P., Guardia, C. M., Estrin, D. A., Vasta, G. R., & Rabinovich, G. A. (2011) · Biochemistry · doi:10.1021/bi201121m · Cited by 282
Self-citationLectins as pattern recognition molecules: The effects of epitope density in innate immunity
Dam, T. K., & Brewer, C. F. (2010) · Glycobiology · doi:10.1093/glycob/cwp186 · Cited by 257
Metadata
- Authors
- Vasta, G. R.
- Venue
- Nature Reviews Microbiology
- Published
- 2009-06
- Volume
- 7
- Issue
- 6
- Pages
- 424-438
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W2068128836
- Cited by
- 535
- References
- 9
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- green
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