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Cited by 663

The DOI matches its Crossref record; 142 of the 142 references it cites were found in a registry or an index.

Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

Open access
Salama, Nina R., Hartung, Mara L., Müller, Anne·2013·Nature Reviews Microbiology

Abstract

The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes approximately 50% of the human population, but only causes overt gastric disease in a subset of infected hosts. In this Review, we discuss the pathogenesis of H. pylori and the mechanisms it uses to promote persistent colonization of the gastric mucosa, with a focus on recent insights into the role of the virulence factors vacuolating cytotoxin (VacA), cytotoxin-associated gene A (CagA) and CagL. We also describe the immunobiology of H. pylori infection and highlight how this bacterium manipulates the innate and adaptive immune systems of the host to promote its own persistence.

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Crossref · 10.1038/nrmicro3016

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Metadata

Authors
Salama, N. R., Hartung, M. L., & Müller, A.
Venue
Nature Reviews Microbiology
Published
2013-05-08
Volume
11
Issue
6
Pages
385-399
ISSN
  • 1740-1526 (ISSN-L)
  • 1740-1534
OpenAlex
W1975213539
Cited by
663
References
142
FWCI
11.83
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. https://app.cochat.ai/papers/10.1038/nrmicro3016
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Salama, N. R., Hartung, M. L., & Müller, A. (2013). Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nature Reviews Microbiology. https://doi.org/10.1038/nrmicro3016

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.