The many faces of insulin-like peptide signalling in the brain
DOI 10.1038/nrn3209
Cited by (877)
Items 701–800 of 877
- Lactobacillus paracasei GF027 promotes growth and cognitive development in juvenile rats via regulating intestinal microecology and nourishing the brainHang Yang, Yuanyifei Wang, Haiwei Liu, Jin Wang, Dancai Fan, Yi Sun, Huan Lv, Wenhui Fu, Shuo Wang · 2025 · Food Bioscience
- Biologically Active Peptides in Invertebrates: Discovery and Functional StudiesQing Yu, Zhidan Liang, Chuanzi OuYang, Lingjun Li · 2015
- Outcome of sub-acute insulin administration on long-term visuo- spatial and short-term working memory in miceVeterinary Physiology · 2016
- Fluorescence Imaging of Huntingtin mRNA KnockdownEunseon Oh, Yuhong Liu, Mahesh V. Sonar, Diane E. Merry, Eric Wickstrom · 2018 · Bioconjugate Chemistry
- Effects of Moxibustion on the Levels of Insulin-Like Growth Factor 1Jaung-Geng Lin, Shinn‐Zong Lin, Lih-Hwa Lin, Chun-Chang Wu, Wan-Ting Tsai, Horng-Jyh Harn, Li-Hui Su, Wen-Yu Ho, Che-Jui Hsieh, Tsung‐Jung Ho · 2018 · Cell Transplantation
- Lower serum insulin-like growth factor 2 level in patients with bipolar disorder is associated with the severity of manic symptoms during manic episodesSeo-Hyeon Ye, Ying Zhao, Zhaobo Liu, Cui-Pin Luo, Jian Xiong, Jin‐Qiong Zhan, Yi‐Heng Li, Bo Wei, Chunnuan Chen, Yuan‐Jian Yang · 2024 · Frontiers in Psychiatry
- Opposite effects of acute and chronic IGF1 on rat dorsal root ganglion neuron excitabilityJennyfer Pastor, Bernard Attali · 2024 · Frontiers in Cellular Neuroscience
- Thermosensory Learning in Caenorhabditis elegans2013 · Handbook of behavioral neuroscience
- SIRT1 in Metabolic Health and DiseaseMarie Boutant, Carles Cantó · 2016 · Springer eBooks
- Transcriptional Regulation of De Novo Lipogenesis in LiverDeqiang Zhang, Lei Yin · 2015 · Springer eBooks
- Altered expression of IGF‐I system in neurons of the inflamed spinal cord during acute experimental autoimmune encephalomyelitisAzita Parvaneh Tafreshi, Farideh Talebi, Samira Ghorbani, Claude C.A. Bernard, Farshid Noorbakhsh · 2017 · The Journal of Comparative Neurology
- Genome plasticity and endocrine diseasesXingang Li, Liang Wang, Xuerui Tan, Wei Wang · 2020 · Elsevier eBooks
- Vascular and neural transcriptomics reveal stage-dependent pathways to inflammation and cognitive dysfunction in a rat model of hypertensionPhilipp Ulbrich, Lorena Morton, Michael Briese, Naomi Lämmlin, Hendrik Mattern, Md. Hasanuzzaman, Melina Westhues, Mahsima Khoshneviszadeh, Silke Appenzeller, Daniel Gündel et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- WITHDRAWN: Biomarker Detection and Therapy of Parkinson's and Alzheimer's disease using upconversion based approach: A Comprehensive ReviewKabirdas B. Ghorpade, Shivanshu Agrawal, Ujwal A. Havelikar · 2025 · Ageing Research Reviews · Retracted
- Aminergic and peptidergic modulation of Insulin-Producing Cells in DrosophilaMartina Held, Rituja S Bisen, Meet Zandawala, Alexander S. Chockley, Isabella S Balles, Selina Hilpert, Sander Liessem, Federico Cascino-Milani, Jan M. Ache · 2025 · eLife
- Active Ingredients and Mechanism of Gegen Qinlian Decoction in the Treatment of Diabetic Cardiomyopathy: A Network Pharmacology StudyMin Wang, Yanbin Liang, Yuce Qin, Ruimian Ma, Huanting Yu, Weixue Wang, Xiaoxi Zhang · 2024 · Current Pharmaceutical Design
- Physical Exercise Benefits Cognition: A Narrative Review of Evidence and Possible MechanismsTzu-Feng Wang, Onanong Mee-inta, Yu‐Min Kuo · 2025 · Advances in neurobiology
- Brain insulin resistance as an early target to attenuate neuroinflammation, oxidative stress and proteinopathies in Alzheimer’s disease: A systematic review of five natural productsReem A. Mohamed, Radwa H. Abdelaziz, Mohamed S. Mohamed, Nayra H. Ahmed, Rouz M. Ahmed · 2025 · Next research.
- KNDy neurons as an indirect target of insulin‐like growth factor‐1Josiane do N. Silva, Ligia M M de Sousa, Maria Eleticia de Sousa, Henrique Rodrigues Vieira, Guilherme Andrade Alves, Nicole T Neifert, Aleisha M. Moore, Jose Donato, Renata Frazão · 2025 · Journal of Neuroendocrinology
- Therapeutic potential of exerkines in neurodegenerative and mental disorders: a narrative reviewSuwol Yang, Hye-Won Sang, Seoyeon Kim, Eun‐Jeong Cho, Youngju Choi, Dong‐Woo Kang, Young Charles Jang, Dong-Ho Park, Hyo‐Bum Kwak, Jang Soo Yook · 2026 · Frontiers in Physiology
- Zfp580 Regulates Paracrine and Endocrine Igf1 and Igfbp3 Differently in the Brain and Blood After a Murine StrokeChristian J. Hoffmann, Melanie T.C. Kuffner, Janet Lips, Stephanie Lorenz, Matthias Endres, Christoph Harms · 2022 · Frontiers in Physiology
- Glucose, glycolysis, and neurodegenerative disordersPatrícia Coelho, Ana Cristina Rego · 2023 · Elsevier eBooks
- Molecular biomarkers of dysphagia targeted exercise induced neuroplasticity: A review of mechanistic processes and preliminary data on detraining effectsRahul Krishnamurthy, Chandan Krishnamoorthy, Angela M. Dietsch, Sathish Kumar Natarajan · 2024 · Brain Research
- Astrocytes of the hippocampus and responses to periprandial neuroendocrine hormonesAna L. Loera‐Lopez, Magen N. Lord, Emily E. Noble · 2025 · Physiology & Behavior
- Updated insights on memory disorder associated risk of medication: A real-world pharmacovigilance analysisMingyang Mao, Mei Wang, Qing Yu, Quanshun Chen, Hong Zhu, Tao Wan, Yi Yang, Jie Zhao · 2025 · Journal of Affective Disorders
- Influence of Lifestyle on Brain Sensitivity to Circulating Insulin-like Growth Factor 1Jonathan Adrian Zegarra-Valdivia, Muhammad Zahid Khan, Aurora Putzolu, Raffaela Cipriani, Jaime Pignatelli, Ignacio Torres‐Alemán · 2025 · International Journal of Molecular Sciences
- Enhancement of Declarative Memory: From Genetic Regulation to Non-invasive StimulationDmitri V. Bryzgalov, Irina L Kuznetsova, Evgeny Ivanovich Rogaev · 2018 · Biochemistry (Moscow)
- Genomic Profile of rIR and rIRR in Type 2 Diabetes Mellitus Rat Model toward Effect of Goat Milk CSN1S2 ProteinSonia Tambunan, Hazna Noor Meidinna, Rista Nikmatu Rohmah, F Fatchiyah · 2019 · Journal of Physics Conference Series
- Dietary Methylselenocysteine and Epigenetic Regulation of Circadian Gene ExpressionHelmut Zarbl, Mingzhu Fang · 2017 · Springer eBooks
- Role of SIRT7 in hepatic lipid metabolismKazuya Yamagata, Md. Fazlul Karim, Yoshifumi Sato, Tatsuya Yoshizawa · 2015 · Diabetology International
- Sirtuins and AgingCarles Cantó, Riekelt H. Houtkooper · 2016 · Springer eBooks
- Sirtuins as Metabolic Modulators of Muscle PlasticityKeir J. Menzies, Julien Francisco Zaldivar‐Jolissaint, Johan H. Auwerx · 2016 · Springer eBooks
- ROLE OF INSULIN-LIKE GROWTH FACTOR IN DEPRESSION: A REVIEWRutu M Patel, Digvijaysinh G. Rana · 2021 · International Research Journal of Pharmacy
- Review of Insulin-Like Growth Factor 1 Signaling Pathway and Its Role in Protection against Brain DiseasesMin Wei, Min Wei, Lun Dong, Hengzhu Zhang, Zhenfei Teng, Xiaodong Wang, 严正村, Lei She, Yuping Li, Xingdong Wang et al. · 2017 · Translational Neuroscience and Clinics
- Regulation of insulin signaling and its developmental and functional roles on peptidergic neurons in the Drosophila central nervous systemJiangnan Luo · 2013 · DiVA (Stockholm University)
- The Acute Effect of Exercise Intensity on Cognitive FunctionSpencer Wikkerink · 2016 · UWSpace (University of Waterloo)
- Insulin signalling activates multiple feedback loops to elicit hunger-induced feeding in DrosophilaSreesha R. Sudhakar, Jishy Varghese · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Axonal Transport Of An Insulin-Like Peptide Mrna Promotes Stress Recovery In C. ElegansRashmi Chandra, Lisa Shi Yun Li, Zahabiya Husain, Shashwat Mishra, Joy Alcedo · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Local autocrine signaling of IGF1 synthesized and released by CA1 pyramidal neurons regulates plasticity of dendritic spinesXun Tu, Anant Jain, Helena Decker, Ryohei Yasuda · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Fractal scaling of C. elegans behavior is shaped by insulin signalingYukinobu Arata, Itsuki Shiga, Yusaku Ikeda, Hiroshi Kimura, Peter Jurica, Ken Kiyono, Yasushi Sako · 2021 · Research Square
- The Neuroprotective Effects of Insulin-Like Growth Factor 1 via the Hippo/YAP Signaling Pathway is Mediated by the PI3K/AKT Pathway Following Cerebral Ischemia-Reperfusion InjuryPian Gong, Yichun Zou, Wei Zhang, Qi Tian, Shoumeng Han, Zhou Xu, Qianxue Chen, Mingchang Li · 2021 · Research Square
- Bibliometric analysis of the interplay between Alzheimer's disease and type 2 diabetes mellitus: Trends, hotspots, and emerging research areasMing Cheng, Ya-Dong Wei, Xin Zheng, Xiaocai Gao, Huaizhi Sun, Jin‐Fang Ge · 2025 · Journal of Alzheimer s Disease
- Role of Vimentin in Injuries of the Central Nervous SystemIgor Manzhulo, Olga S. Manzhulo, Arina I. Ponomarenko · 2025 · Neurochemical Journal
- Grueneberg Ganglion: An Unexplored Site for Intranasal Drug Delivery in Alzheimer’s DiseaseViolina Kakoty, Ji Hee Kang, O Hyun Lee, Da Hee Oh, Young Tag Ko · 2025 · ACS Chemical Neuroscience
- Interoceptive Signaling by Circulating Insulin Like Growth Factor I and Neuroprotection by ExerciseJonathan Adrian Zegarra-Valdivia, María Estrella Fernández de Sevilla, Jaime Pignatelli, Ignacio Torres‐Alemán · 2025 · Advances in neurobiology
- Development of a novel pH-Responsive poly (3, 4-ethylenedioxythiophene) with aminated guar gum hydrogel for controlled delivery of IGF in pregnancy-associated placental disordersXuan Zhang, Suyan Gu, Xueyan Shen, Botao Yang, Yaqin Li, Cuihong Gao, Rongjuan Yang, Xiuqing Zhou, Na Wang, Yao Zhang · 2025 · Journal of Drug Delivery Science and Technology
- An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct signalingIrena Selicharová, Nicholas S. Kirk, Anna Kertisová, Marta Lubos, Katarína Mitrová, Terezie Ticháčková, Lenka Žáková, Martina Chrudinová, Jana Březinová, Karel Harant et al. · 2026 · Science Advances
- Nutritional Signaling and AgingCarsten Carlberg, Stine Marie Ulven, Ferdinand Molnár · 2016 · Springer eBooks
- Assessing Gene Expression and Methylation of KMT2D and IGF2 Genes in Patients with Non-Small Cell Lung CancerArash Matinahmadi, Hessamodin Ghasemi, Sajad Nooshin, Zoofa Zayani, Shohreh Zare Karizi, Morteza Karimipoor · 2018 · Cancer and Clinical Oncology
- Neurodevelopment, Intestinal Function, and AutismEdwin Chau-Leung Yu · 2018 · Neonatal and Pediatric Medicine
- Lint, a transmembrane serine protease, regulates growth and metabolism in DrosophilaHimani Pathak, Ananthakrishnan Vijayakumar Maya, Abdul Basith Tanari, Sohela Sarkar, Jishy Varghese · 2021 · Genetics
- Impact of aerobic exercise on brain structure in models of agingLars Stiernman Jonasson, Chelsea M. Stillman, Kirk I. Erickson · 2021 · Elsevier eBooks
- Phytonanoparticles toward the treatment of diabetesTriveni Shelke, Sushma Talegaonkar, Monalisa Mishra · 2022 · Elsevier eBooks
- Exercise and the Brain: Aerobic-Based Exercise Protocols and Cognitive Functions in Children and Adolescents: Traditional ReviewUmut Canlı · 2022 · Turkiye Klinikleri Journal of Sports Sciences
- Effects of Acute Caffeine Intake on Insulin-Like Growth Factor-1 Responses to Total Sleep Deprivation: Interactions with COMT Polymorphism – A Randomized, Crossover StudyCatherine Drogou, Fabien Sauvet, Mégane Erblang, Damien Léger, Claire Thomas, Mounir Chennaoui, Danielle Gomez-Mérino, Investigators group · 2023 · Lifestyle Genomics
- Growth factors and their receptorsMohd Aizuddin Mohd Lazaldin, Lidawani Lambuk, Suhana Ahmad, Rohimah Mohamud · 2023 · Elsevier eBooks
- Alternsumkehr und LebensspannenverlängerungLeo Cornelius Bollheimer, Dorothee Volkert, Thomas Bertsch, Cornel Christian Sieber, Reinhard Büttner · 2012 · Zeitschrift für Gerontologie und Geriatrie
- Insulin-like Growth Factor Binding Protein6 Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage in RatsQijun Dai, Peipei Jiang, Yang Gu, Lin Zhu, Haifeng Dai, Zhigang Yao, Hua Liu, Xiaoping Ma, Chengwei Duan, Lianxia Qu · 2017 · Cellular and Molecular Neurobiology
- Heterologous expression of mitochondrial nicotinamide adenine dinucleotide transporter (Ndt1) from Aspergillus fumigatus rescues impaired growth in Δndt1Δndt2 Saccharomyces cerevisiae strainLaís de Lourdes de Lima Bálico, Emerson de Souza Santos, Silveli Suzuki‐Hatano, Lucas Oliveira Sousa, Ana Elisa Caleiro Seixas Azzolini, Yara Maria Lucisano-Valim, Taísa Magnani Dinamarco, Vinicius Kannen, Sérgio Akira Uyemura · 2017 · Journal of Bioenergetics and Biomembranes
- Rett Syndrome: Treatment with IGF-I, Melatonin, Blackcurrant Extracts, and RehabilitationJesús Devesa, Olga Devesa, María Carrillo, Nerea Casteleiro, Ana Devesa, David Llorente, Cristina González · 2018 · Reports — Medical Cases Images and Videos
- Insulin resistance and Alzheimer’s diseaseA. A. Farooqui · 2020 · Elsevier eBooks
- Building a schizophrenia genetic network: Transcription Factor 4 regulates genes involved in neuronal development and schizophrenia riskHanzhang Xia, Fay M. Jahr, Nak-Kyeong Kim, Linying Xie, Andrey A. Shabalin, Julien Bryois, Douglas H. Sweet, Mohamad M. Kronfol, Preetha Palasuberniam, MaryPeace McRae et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Insulin-Like Growth Factor I Modulates Vulnerability to Stress Through Orexin NeuronsME Fernandez de Sevilla, Jaime Pignatelli, Pablo Méndez, Jonathan Adrian Zegarra-Valdivia, I Torres Alemán · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Time-restricted feeding near dawn entrains long-term behavioral changes through the suprachiasmatic nucleusQiaocheng Zhai, Yizhun Zeng, Yue Gu, Tao Zhang, Baoshi Yuan, Tao Wang, Jie Yu Yan, Han Qin, Ling Yang, Xiaowei Chen et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Trimethylamine N-Oxide (TMAO) links peripheral insulin resistance and cognitive deficiencies in a senescence accelerated mouse modelManuel H. Janeiro, Elena Puerta, María Lanz, Fermin Ignacio Milagro, María Javier Ramírez, Maite Solas · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Restructuring of an asymmetric neural circuit during associative learningLeo T. H. Tang, Garrett A. Lee, Steven J. Cook, Jacquelin Ho, Cassandra C. Potter, Hannes E. Bülow · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Modulation of Integrin αvβ3 Activation and Signaling in BV-2 Microglial Cells and THP-1 Monocytes by Thyroid HormonesFabio Gionfra, Veronica D’Ezio, Roberto De Luca, Elena Candelotti, Stefano Leone, Zulema Antonia Percario, Tiziana Persichini, Marco Colasanti, Elisabetta Affabris, Hung‐Yun Lin et al. · 2024 · Preprints.org
- The function of TCF4 in Pitt-Hopkins syndrome and schizophreniaMarc P. Forrest · 2013 · ORCA Online Research @Cardiff (Cardiff University)
- Cellular and molecular mechanisms implicated in pathogenesis of selective neurodegeneration in Huntington’s diseaseJeffrey P. Cantle, Xiao‐Hong Lu, Xiaofeng Gu, X. William Yang · 2012 · Frontiers in Biology
- Carcinogenic Compounds, 2-nitrofluorene and Clonidine Can Modulate the Level of Sirtuin mRNAs Expression in Human Adipose Tissue-derived Stem CellsJiyoun Lee, Chae-yeong Lee, Young-Ho Kwon, Ho-Chan Kim, Hyun Kim · 2014 · Korean Journal of Physical Anthropology
- Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes toFernanda G. De Felice, Sergio Teixeira Ferreira · 2014
- Insulin Action in Brain Regulates Systemic Metabolism and BrainAndré Kleinridders, Heather Anne Ferris, Weikang Cai, C. Ronald Kahn · 2014
- Fortuitous benefits of activity-based rehabilitation in stem cell-based therapy for spinal cord repair: enhancing graft survivalByung Gon Kim, Dong Hoon Hwang, Hae‐Young Shin · 2015 · Neural Regeneration Research
- Voies de signalisation non-canoniques du récepteur V2 de la vasopressineJoris Zhou · 2013
- INSULIN GROWTH FACTOR I AND ITS RECEPTOR ARE ANTAGONISTIC MODULATORS OF GLUCOSE HANDLING BY ASTROCYTESEdwin Hernández-Garzón, Ana Maria Fernandez, Alberto Pérez‐Alvarez, Sara Mederos, Paloma Pérez‐Domper, Pablo Bascuñana, Rubén Fernández de la Rosa, Mercedes Delgado, Miguel A. Pozo, Antonio Miranda‐Vizuete et al. · 2015 · bioRxiv (Cold Spring Harbor Laboratory)
- Cerebral ageing-the role of insulin and insulin-like growth factor signalling: A reviewGeorgia Romain · 2014 · World Journal of Neurology
- Neuroprotección conferida por agonistas PPARs E IGF-1 y su impacto en vías de supervivencia en dos modelos in vitro de la enfermedad de KrabbeMartínez Galarza, David Ernesto · 2014
- Exenatide as a novel treatment for Parkinson's DiseaseIcíar Avilés-Olmos · 2013 · UCL Discovery (University College London)
- Genetic Overlap Between Depression and Cardiometabolic DisordersAzmeraw T. Amare, Klaus Oliver Schubert, Bernhard Theodor Baune · 2016 · Springer eBooks
- Insulin-like Growth Factor 1 for Healthy Spines and Healthy Minds?Sandhya Chandrasekaran, Schahram Akbarian · 2016 · Biological Psychiatry
- Molecular mechanisms underlying the neuroprotective effect of IGF-1 in neuroblastoma cells and the pro-metastatic effect of Dph3 in murine melanoma cellsLei Wang · 2013 · DR-NTU (Nanyang Technological University)
- NAD+ as a Pharmacological Tool to Boost Sirtuin ActivityRiekelt H. Houtkooper · 2016 · Springer eBooks
- Growth and Neurotrophic Factors in HIV-Associated Neurocognitive DisordersPalsamy Periyasamy, Ming‐Lei Guo, Shilpa J. Buch · 2016 · Springer eBooks
- The interactive effects of genetics and cardiorespiratory fitness level on cognitive performance in healthy older adultsJennifer Kim · 2016 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
- Spatio-Temporal Control of Cellular and Organismal Physiology by SirtuinsShaunak Deota, Namrata Shukla, Ullas Kolthur‐Seetharam · 2017 · Journal of the Indian Institute of Science
- Molecular Mechanisms of Cardiovascular AgingFrancesca Tarantini, Claudia Di Serio, Luigi Ferrucci · 2017 · Springer eBooks
- Morphological study of cell protrusions during redirected migration in human fibroblast cellsCongyingzi Zhang · 2013 · OhioLink ETD Center (Ohio Library and Information Network)
- Type II Diabetes and Metabolic Syndrome as Risk Factors for Alzheimer’s DiseaseA. A. Farooqui · 2017 · Elsevier eBooks
- Energy Metabolism and EpigeneticsScott J. Bultman · 2017 · Springer eBooks
- Biological and Behavioural Markers of Parkinson’s DiseaseYassar Alamri · 2017 · Otago University Research Archive (University of Otago)
- Dietary Methylselenocysteine and Epigenetic Regulation of Circadian Gene ExpressionHelmut Zarbl, Mingzhu Fang · 2019 · Springer eBooks
- Terapia celular y génica con timulina E IGF-1 en modelos animales de neuroinflamaciónMaría Florencia Zappa Villar · 2018 · El Servicio de Difusión de la Creación Intelectual (National University of La Plata)
- Insulin-like Growth Factor Signaling and Action in the Brain ☆Vincenzo Carlo Russo, George Arthur Werther · 2017 · Elsevier eBooks
- Hormones of energy homeostasis : linking weight loss and cognition in Parkinson's disease?Fionnuala Johnston · 2018
- Brain-Gut Molding Aberrant Development Trajectory in Autistic ChildrenEdwin Chau Leung Yu · 2019 · Academic Journal of Pediatrics & Neonatology
- INSULINO-RESISTENZA E CERVELLO: EVIDENZE MOLECOLARI E NUOVI BIOMARCATORI ALLA BASE DEL LEGAME TRA PATOLOGIE METABOLICHE E NEURODEGENERATIVESalvatore Fusco, Matteo Spinelli, Claudio Grassi · 2019 · il Diabete
- Terapia génica anti-inflamatoria en el abordaje de la neurodegeneración dopaminérgica motoraEugenia Falomir Lockhart · 2020 · El Servicio de Difusión de la Creación Intelectual (National University of La Plata)
- Age-dependent changes of neural functions under glucose metabolism disordersViktoria N. Shadenko · 2020 · Journal of the Belarusian State University Biology
- Loss of Setd1b methyltransferase in the murine forebrain as a novel model for human intellectual disabilityAlexandra Michurina · 2020 · eDiss (Georg-August-Universität Göttingen)
- Target Proteins Involved in Aging Mechanism as an Aging Molecular MarkerMoon‐Moo Kim · 2016 · Journal of Life Science