Male sexual dysfunction and HIV – A clinical perspective
Abstract
Sexual dysfunction in men with HIV is often overlooked by clinicians owing to many factors, including the taboo of sexuality. The improved life expectancy of patients with HIV requires physicians to consider their general wellbeing and sexual health with a renewed interest. However, data on sexual dysfunction in those with HIV are scarce. Erectile dysfunction (ED) is the most common sexual dysfunction in men, with a prevalence of ∼30-50% and is frequent even in men <40 years of age. HIV infection itself is the strongest predictor of ED, and many factors related to the infection-fear of virus transmission, changes in body image, HIV-related comorbidities, infection stigma, obligatory condom use-all impair erectile function. The diagnosis and treatment of sexual dysfunction is based on a multidisciplinary approach, which involves specialists in both infectious diseases and sexual medicine. Particular attention should be paid to the promotion of safer sex in these patients. This Review, describes the issues surrounding sexual dysfunction in men with HIV and aims to provide clinical advice for the physician treating these patients.
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Higher prevalence rates of ED are found in men with HIV, which could be attributed to organic factors such as the use of protease inhibitor medication inducing androgen deficiency, as well as psychosocial factors such as psychological distress, low social support and discrimination, fear of rejection and fear of transmission.
“Higher prevalence rates of ED are also found in men with HIV, which could be attributed to organic factors such as the use of protease inhibitor medication inducing androgen deficiency, as well as psychosocial factors such as psychological distress, low social support and discrimination, fear of rejection and fear of transmission.76,77”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [77]
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“Higher prevalence rates of ED are also found in men with HIV, which could be attributed to organic factors such as the use of protease inhibitor medication inducing androgen deficiency, as well as psychosocial factors such as psychological distress, low social support and discrimination, fear of rejection and fear of…”
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- Authors
- Santi, D., Brigante, G., Zona, S., Guaraldi, G., & Rochira, V.
- Affiliations
- University of Modena and Reggio Emilia (IT)
- Corresponding author
- Rochira, Vincenzo
- Venue
- Nature Reviews Urology
- Published
- 2014-01-07
- Volume
- 11
- Issue
- 2
- Pages
- 99-109
- ISSN
- 1759-4812 (ISSN-L)
- 1759-4820
- OpenAlex
- W2078945036
- Cited by
- 56
- References
- 92
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 6 · 2023: 6 · 2022: 5 · 2021: 11 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 2 · 2016: 6 · 2015: 5 · 2014: 1
- FWCI
- 0.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Reviews Urology (publishedVersion)
- PubMed (publishedVersion)
- IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Keywords
- erectile dysfunction, HIV, male sexual dysfunction, sexual health, HIV stigma, condom use, body image, HIV comorbidities, safer sex, multidisciplinary management, sexual medicine
- MeSH terms
- Decision Trees, Humans, Erectile Dysfunction, Male, HIV Infections
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