BMI and Health Status Among Adults With Asthma
Open accessAbstract
Background: A convincing body of literature links obesity with a higher risk for developing adult‐onset asthma. The impact of obesity on asthma severity among adults with pre‐existing asthma, however, is less clear. Methods and Procedures: In a prospective cohort study of 843 adults with severe asthma, we studied the impact of BMI on asthma health status. Results: The prevalence of obesity and overweight were 44% (95% confidence interval (CI) 41–47%) and 28% (95% CI 25–32%). The obese BMI group was associated with a higher risk for daily or near daily asthma symptoms than was the normal BMI group (odds ratio (OR) 1.81; 95% CI 1.10–2.96). Compared to the normal BMI group, generic physical health status was worse in the overweight (mean score decrement −2.42 points; 95% CI −4.39 to −0.45) and the obese groups (−6.31 points; 95% CI −8.14 to −4.49). Asthma‐specific quality of life was worse in the underweight (mean score increment 8.66 points; 95% CI 2.53–14.8) and obese groups (4.51 points; 95% CI 2.21–6.81), compared to those with normal BMI. Obese persons also had a higher number of restricted activity days that past month (5.05 days; 95% CI 2.90–7.19 days). Discussion: It appears that obesity has a substantive negative effect on health status among adults with asthma. Further work is needed to clarify the precise mechanisms. Clinicians should counsel dietary modification and weight loss for their overweight and obese patients with asthma.
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- Authors
- Vortmann, M., & Eisner, M. D.
- Affiliations
- University of California, San Francisco (US)
- Kaiser Permanente (US)
- Corresponding author
- Eisner, Mark D.
- ORCID
- Eisner, Mark D.
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2008-01
- Volume
- 16
- Issue
- 1
- Pages
- 146-152
- ISSN
- 1930-7381 (ISSN-L)
- 1930-739X
- OpenAlex
- W1991044324
- Cited by
- 123
- References
- 61
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 7 · 2023: 6 · 2022: 11 · 2021: 9 · 2020: 4 · 2019: 7 · 2018: 5 · 2017: 4 · 2016: 8 · 2015: 5 · 2014: 7 · 2013: 7 · 2012: 17
- FWCI
- 4.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Obesity (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Social Security Administration
- Kaiser Foundation Research Institute
- National Heart, Lung, and Blood Institute (K23HL004201, K23 HL-04201)
- Topics
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- body mass index, asthma, severe asthma, health status, asthma symptoms, quality of life, physical health status, restricted activity days, overweight, underweight, weight loss, dietary change
- MeSH terms
- Activities of Daily Living, Adult, Aged, Aged, 80 and over, Asthma, California, Female, Health Status, Humans, Male, Middle Aged, Obesity, Prospective Studies, Quality of Life, Risk Factors, Severity of Illness Index, Cohort Studies, Body Mass Index, Linear Models
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