Bariatric surgery: a potential cure for asthma?
Open accessAbstract
Asthma incidence and severity are increased in obese populations. Systematic reviews have shown benefit from weight-loss interventions on asthma outcomes, but the role of bariatric surgery is still unclear. In this review, cohorts of obese asthmatic patients undergoing bariatric surgery were examined regarding different asthma outcomes. The available data on patients who were followed up showed improvements in asthma control, exacerbation risk, asthma-related hospitalisation, medication use and airway hyperresponsiveness, with some patients not requiring further treatment for asthma. Follow-up duration was variable, being mostly of 1 year, with some studies reporting long-term outcomes after 5 years. The studies reviewed had many limitations, including small numbers of patients, lack of control arm in some studies and lack of standardisation of asthma diagnosis, classification and outcome measures, in addition to possible reporting bias. Data on small numbers of patients also show the possibility of benefit exclusively in nonallergic asthma. Larger, more stringent clinical trials are needed before recommending bariatric surgery for treatment of asthma.
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Reductions in markers of airway hyper-responsiveness and asthma-related inflammation occur after bariatric surgery.
“Reductions in markers of airway hyper-responsiveness and asthma-related inflammation occur after the procedure [81].”
From Bariatric surgery: remission of inflammation, cardiometabolic benefits, and common adverse effects (2020) · cites this paper as [81]
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Bariatric surgery: remission of inflammation, cardiometabolic benefits, and common adverse effects
Biobaku, F., Ghanim, H., Monte, S. V., Caruana, J. A., & Dandona, P. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa049 · Cited by 68 · see citing works
- Authors
- Chaaban, T. A.
- Affiliations
- The Ohio State University Wexner Medical Center (US)
- Corresponding author
- Chaaban, Toufic A.
- ORCID
- Chaaban, Toufic A.
- Venue
- European Respiratory Review
- Publisher
- European Respiratory Society (ERS)
- Published
- 2019-06-30
- Volume
- 28
- Issue
- 152
- Pages
- 190003
- ISSN
- 0905-9180 (ISSN-L)
- 1600-0617
- PMC
- PMC9488568
- OpenAlex
- W2961000776
- Cited by
- 26
- References
- 59
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 8 · 2023: 1 · 2022: 2 · 2021: 7 · 2020: 4
- FWCI
- 0.67
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- European Respiratory Review (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Airway Management and Intubation Techniques
- Keywords
- bariatric surgery, asthma, obesity, weight loss, asthma control, asthma exacerbations, asthma medication use, airway hyperresponsiveness, non-allergic asthma, long-term outcomes
- MeSH terms
- Asthma, Humans, Lung, Obesity, Risk Factors, Severity of Illness Index, Time Factors, Weight Loss, Incidence, Prevalence, Treatment Outcome, Anti-Asthmatic Agents, Bariatric Surgery
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