The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission
Open accessAbstract
The concept of the antibiotic resistome was introduced just over a decade ago, and since then, active resistome studies have been conducted. In the present study, we describe the previously established concept of the resistome, which encompasses all types of antibiotic resistance genes (ARGs), and the important findings from each One-Health sector considering this concept, thereby emphasizing the significance of the One-Health approach in understanding ARG transmission. Cutting-edge research methodologies are essential for deciphering the complex resistome structure in the microbiomes of humans, animals, and the environment. Based on the recent achievements of resistome studies in multiple One-Health sectors, future directions for resistome research have been suggested to improve the understanding and control of ARG transmission: (1) ranking the critical ARGs and their hosts; (2) understanding ARG transmission at the interfaces of One-Health sectors; (3) identifying selective pressures affecting the emergence, transmission, and evolution of ARGs; and (4) elucidating the mechanisms that allow an organism to overcome taxonomic barriers in ARG transmission.
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Cited by
Fu, Y., Dou, Q., Smalla, K., Wang, Y., Johnson, T. A., Brandt, K. K., Mei, Z., Liao, M., Hashsham, S. A., Schäffer, A., et al. (2023) · mLife · doi:10.1002/mlf2.12101 · Cited by 65
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Breastfeeding and early Bifidobacterium-driven microbial colonization shape the infant gut resistome
Samarra, A., Alcañiz, A. J., Martínez-Costa, C., Marina, A., Comas, I., Segata, N., Quijada, N. M., & Collado, M. C. (2025) · Nature Communications · doi:10.1038/s41467-025-61154-w · Cited by 32
Prediction of antibiotic resistance mechanisms using a protein language model
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“Since then, environmental, human, and animal resistomes have been thoroughly studied in line with the One-Health perspective (Kim & Cha, 2021) however investigations of food resistomes have been limited (Leech et al., 2020; T ´ oth et al., 2020; Walsh, Macori, Kilcawley, & Cotter, 2020; Yasir,…”
Metadata
- Authors
- Kim, D.-W., & Cha, C.-J.
- Venue
- Experimental & Molecular Medicine
- Published
- 2021-03
- Volume
- 53
- Issue
- 3
- Pages
- 301-309
- ISSN
- 1226-3613 (ISSN-L)
- 2092-6413
- OpenAlex
- W3135303689
- Cited by
- 355
- References
- 117
- FWCI
- 13.07
- Type
- journal article
- Language
- en
- Open access
- gold
- Licence
- creativecommons.org/licenses/by/4.0 (tdm)
- creativecommons.org/licenses/by/4.0 (vor)
- Funders
- MOE | Korea Environmental Industry and Technology Institute (2016001350004)
- Ministry of Health, Welfare and Family Affairs | Korea Centers for Disease Control & Prevention (2017ER540701)
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- Kim, D.-W., & Cha, C.-J. (2021). Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission. Experimental & Molecular Medicine. https://doi.org/10.1038/s12276-021-00569-z
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
