Sampling the Antibiotic Resistome

Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance

Chopra, I., & Roberts, M. (2001) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.65.2.232-260.2001 · Cited by 4,517 · see citing works

Inactivation of Antibiotics and the Dissemination of Resistance Genes

DAVIES, J. E. (1994) · Science · doi:10.1126/science.8153624 · Cited by 1,729 · see citing works

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

Gellert, M. F., Mizuuchi, K., O'Dea, M. H., Itoh, T., & Tomizawa, J.-I. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.11.4772 · Cited by 834 · see citing works

Antibiotics

Walsh, C. T. (2003) · Wiley eBooks · doi:10.1128/9781555817886 · Cited by 630 · see citing works

Mechanism of plasmid-mediated quinolone resistance

Tran, J. H., & Jacoby, G. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.082092899 · Cited by 568 · see citing works

Antimicrobial Resistance among Clinical Isolates of Streptococcus pneumoniae in the United States during 1999–2000, Including a Comparison of Resistance Rates since 1994–1995

Doern, G. V., Heilmann, K. P., Huynh, H. K., Rhomberg, P. R., Coffman, S. L., & Brueggemann, A. B. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.6.1721-1729.2001 · Cited by 537 · see citing works

Uncultured soil bacteria are a reservoir of new antibiotic resistance genes

Riesenfeld, C. S., Goodman, R. M., & Handelsman, J. (2004) · Environmental Microbiology · doi:10.1111/j.1462-2920.2004.00664.x · Cited by 528 · see citing works

Vancomycin Assembly: Nature's Way

Hubbard, B. K., & Walsh, C. T. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200390202 · Cited by 356 · see citing works

Structural Transitions as Determinants of the Action of the Calcium-Dependent Antibiotic Daptomycin

Jung, D., Rozek, A., Okon, M., & Hancock, R. E. W. (2004) · Chemistry & Biology · doi:10.1016/j.chembiol.2004.04.020 · Cited by 298 · see citing works

Vancomycin Assembly: Nature′s Way

Hubbard, B. K., & Walsh, C. T. (2003) · ChemInform · doi:10.1002/chin.200322284 · Cited by 294 · see citing works

Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions.

Peng, H., & Marians, K. J. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80551-1 · Cited by 263 · see citing works

Glycopeptide Antibiotic Resistance Genes in Glycopeptide-Producing Organisms

Marshall, C. G., Lessard, I. A. D., Park, I.-S., & Wright, G. D. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.9.2215 · Cited by 252 · see citing works

Daptomycin disrupts membrane potential in growing Staphylococcus aureus

Alborn, W. E., Allen, N. E., & Preston, D. A. (1991) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.35.11.2282 · Cited by 213 · see citing works

Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: The synthesis and evaluation of daptomycin (LY146032).

Debono, M., Abbott, B. J., MOLLOY, R. M., et al. (1988) · The Journal of Antibiotics · doi:10.7164/antibiotics.41.1093 · Cited by 204 · see citing works

Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids.

Thompson, C. J., & Gray, G. S. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.17.5190 · Cited by 159 · see citing works

Macrolide resistance and erythromycin resistance determinants among Belgian Streptococcus pyogenes and Streptococcus pneumoniae isolates

Descheemaeker, P., Chapelle, S., Lammens, C., et al. (2000) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/45.2.167 · Cited by 131 · see citing works

A signal transduction system in Streptomyces coelicolor that activates the expression of a putative cell wall glycan operon in response to vancomycin and other cell wall‐specific antibiotics

Hong, H., Paget, M. S. B., & Buttner, M. J. (2002) · Molecular Microbiology · doi:10.1046/j.1365-2958.2002.02960.x · Cited by 108 · see citing works

Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli

Noguchi, N., EMURA, A., Matsuyama, H., et al. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.10.2359 · Cited by 102 · see citing works

Comparative In Vitro Activities of Daptomycin and Vancomycin against Resistant Gram-Positive Pathogens

Snydman, D. R., Jacobus, N. V., McDermott, L. A., et al. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.12.3447-3450.2000 · Cited by 102 · see citing works

Life without dihydrofolate reductase FolA

Myllykallio, H., Leduc, D., Filée, J., et al. (2003) · Trends in Microbiology · doi:10.1016/s0966-842x(03)00101-x · Cited by 92 · see citing works

The tylosin-biosynthetic genes of Streptomyces fradiae

Cundliffe, E., Bate, N., Butler, A. R., et al. (2001) · Antonie van Leeuwenhoek · doi:10.1023/a:1012065300116 · Cited by 79 · see citing works

Baseline Study To Determine In Vitro Activities of Daptomycin against Gram-Positive Pathogens Isolated in the United States in 2000-2001

Critchley, I. A., Blosser-Middleton, R. S., Jones, M. E., et al. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.5.1689-1693.2003 · Cited by 75 · see citing works

Glycosylation of macrolide antibiotics in extracts of Streptomyces lividans

Cundliffe, E. (1992) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.36.2.348 · Cited by 67 · see citing works

Occurrence, Structure, and Mobility of Tn 1546 -Like Elements in Environmental Isolates of Vancomycin-Resistant Enterococci

Guardabassi, L., & Dalsgaard, A. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.2.984-990.2004 · Cited by 63 · see citing works

Amino acid variation in the GyrA subunit of bacteria potentially associated with natural resistance to fluoroquinolone antibiotics

Waters, B., & Davies, J. (1997) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.41.12.2766 · Cited by 53 · see citing works

Cyclophosphamide and Etoposide for Non-Small Cell and Small Cell Lung Cancer

Grunberg, S. M. (1999) · Drugs · doi:10.2165/00003495-199958003-00002 · Cited by 31 · see citing works

Origins and evolution of antibiotic resistance

Davies, J., & Davies, D. (2010) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00016-10 · Cited by 5,784 · see citing works

Antibiotic resistance is ancient

D’Costa, V. M., King, C. E., Kalan, L., Morar, M., Sung, W. W. L., Schwarz, C., Froese, D., Zazula, G., Calmels, F., Debruyne, R., et al. (2011) · Nature · doi:10.1038/nature10388 · Cited by 2,720 · see citing works

Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer

von Wintersdorff, C. J. H., Penders, J., van Niekerk, J. M., Mills, N. D., Majumder, S., van Alphen, L. B., Savelkoul, P. H. M., & Wolffs, P. F. G. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00173 · Cited by 1,707 · see citing works

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

Brauner, A., Fridman, O., Gefen, O., & Balaban, N. Q. (2016) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.34 · Cited by 1,612 · see citing works

The shared antibiotic resistome of soil bacteria and human pathogens

Forsberg, K. J., Reyes, A., Wang, B., Selleck, E. M., Sommer, M. O. A., & Dantas, G. (2012) · Science · doi:10.1126/science.1220761 · Cited by 1,650 · see citing works

Efflux-mediated antimicrobial resistance

Poole, K. (2005) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dki171 · Cited by 1,082 · see citing works

Functional characterization of the antibiotic resistance reservoir in the human microflora

Sommer, M. O. A., Dantas, G., & Church, G. M. (2009) · Science · doi:10.1126/science.1176950 · Cited by 878 · see citing works

The human microbiome: Our second genome

Grice, E. A., & Segre, J. A. (2012) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090711-163814 · Cited by 759 · see citing works

Antibiotic resistance is prevalent in an isolated cave microbiome

Bhullar, K., Waglechner, N., Pawlowski, A., Koteva, K., Banks, E. D., Johnston, M. D., Barton, H. A., & Wright, G. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034953 · Cited by 736 · see citing works

The Scourge of Antibiotic Resistance: The Important Role of the Environment

Finley, R. L., Collignon, P., Larsson, D. G. J., McEwen, S. A., Li, X.-Z., Gaze, W. H., Reid-Smith, R., Timinouni, M., Graham, D. W., & Topp, E. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit355 · Cited by 636 · see citing works

An overview of the last 10 years of genetically engineered crop safety research

Nicolia, A., Manzo, A., Veronesi, F., & Rosellini, D. (2014) · Critical Reviews in Biotechnology · doi:10.3109/07388551.2013.823595 · Cited by 413 · see citing works

Counteraction of antibiotic production and degradation stabilizes microbial communities

Kelsic, E. D., Zhao, J., Vetsigian, K., & Kishony, R. (2015) · Nature · doi:10.1038/nature14485 · Cited by 344 · see citing works

Antimicrobial usage and resistance in beef production

Cameron, A., & McAllister, T. A. (2016) · Journal of Animal Science and Biotechnology · doi:10.1186/s40104-016-0127-3 · Cited by 207 · see citing works

The Food Production Environment and the Development of Antimicrobial Resistance in Human Pathogens of Animal Origin

Lekshmi, M., Ammini, P., Kumar, S., & Varela, M. F. (2017) · Microorganisms · doi:10.3390/microorganisms5010011 · Cited by 194 · see citing works

An analysis of FDA-approved drugs for infectious disease: antibacterial agents

Kinch, M. S., Patridge, E., Plummer, M., & Hoyer, D. (2014) · Drug Discovery Today · doi:10.1016/j.drudis.2014.07.005 · Cited by 115 · see citing works

Antibiotic resistance by enzyme inactivation: From mechanisms to solutions

De Pascale, G., & Wright, G. D. (2010) · ChemBioChem · doi:10.1002/cbic.201000067 · Cited by 94 · see citing works

Using Combination Therapy to Thwart Drug Resistance

Hill, J. A., & Cowen, L. E. (2015) · Future Microbiology · doi:10.2217/fmb.15.68 · Cited by 75 · see citing works

Mycoplasmas and Their Antibiotic Resistance: The Problems and Prospects in Controlling Infections

Chernova, O. A., Medvedeva, E. S., Mouzykantov, A. A., Baranova, N. B., & Chernov, V. M. (2016) · Acta Naturae · doi:10.32607/20758251-2016-8-2-24-34 · Cited by 66 · see citing works

Antibiotic research in the age of omics: from expression profiles to interspecies communication

Wecke, T., & Mascher, T. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr373 · Cited by 62 · see citing works

Gut microbiota research nexus: One Health relationship between human, animal, and environmental resistomes

Fu, Y., Dou, Q., Smalla, K., Wang, Y., Johnson, T. A., Brandt, K. K., Mei, Z., Liao, M., Hashsham, S. A., Schäffer, A., et al. (2023) · mLife · doi:10.1002/mlf2.12101 · Cited by 65 · see citing works

Genes homologous to glycopeptide resistance<i>van</i>A are widespread in soil microbial communities

Guardabassi, L., & Agersø, Y. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00270.x · Cited by 47 · see citing works

Potential influence of antimicrobial resistance gene content in probiotic bacteria on the gut resistome ecosystems

Radovanovic, M., Kekic, D., Gajic, I., Kabic, J., Jovicevic, M., Kekic, N., Opavski, N., & Ranin, L. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1054555 · Cited by 42 · see citing works

The soil resistome: The anthropogenic, the native, and the unknown

Cytryn, E. J. (2013) · Soil Biology and Biochemistry · doi:10.1016/j.soilbio.2013.03.017 · Cited by 189 · see citing works

The wastewater resistome: Lurking antibiotic resistance in the environment

Joshi, D. R. (2018) · Tribhuvan University Journal of Microbiology · doi:10.3126/tujm.v4i0.21681 · Cited by 4 · see citing works

Withdraw of prophylactic antimicrobials does not change the pigs’ resistomePreprint

Fernanda, L.-V., Alejandro, T., Lixin, Z., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/716597

Next-generation approaches to understand and combat the antibiotic resistome

Crofts, T. S., Gasparrini, A. J., & Dantas, G. A. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.28 · Cited by 533 · see citing works

Exploring the Animal Waste Resistome: The Spread of Antimicrobial Resistance Genes Through the Use of Livestock Manure

Checcucci, A., Trevisi, P., Luise, D., Modesto, M., Blasioli, S., Braschi, I., & Mattarelli, P. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01416 · Cited by 155 · see citing works