The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Tailoring photosensitive ROS for advanced photodynamic therapy
Open accessAbstract
Photodynamic therapy (PDT) has been considered a noninvasive and cost-effective modality for tumor treatment. However, the complexity of tumor microenvironments poses challenges to the implementation of traditional PDT. Here, we review recent advances in PDT to resolve the current problems. Major breakthroughs in PDTs are enabling significant progress in molecular medicine and are interconnected with innovative strategies based on smart bio/nanomaterials or therapeutic insights. We focus on newly developed PDT strategies designed by tailoring photosensitive reactive oxygen species generation, which include the use of proteinaceous photosensitizers, self-illumination, or oxygen-independent approaches. While these updated PDT platforms are expected to enable major advances in cancer treatment, addressing future challenges related to biosafety and target specificity is discussed throughout as a necessary goal to expand the usefulness of PDT.
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Cites
Photodynamic therapy of cancer: An update
Agostinis, P., Berg, K., Cengel, K. A., Foster, T. H., Girotti, A. W., Gollnick, S. O., Hahn, S. M., Hamblin, M. R., Juzeniene, A., Kessel, D., et al. (2011) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.20114 · Cited by 5,145
Photodynamic therapy – mechanisms, photosensitizers and combinations
Kwiatkowski, S., Knap, B., Przystupski, D., Saczko, J., Kędzierska, E., Knap-Czop, K., Kotlińska, J., Michel, O., Kotowski, K., & Kulbacka, J. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.07.049 · Cited by 2,173
HIF-1α pathway: role, regulation and intervention for cancer therapy
Masoud, G. N., & Li, W. (2015) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2015.05.007 · Cited by 1,871
Hypoxia signalling in cancer and approaches to enforce tumour regression
Pouysségur, J., Dayan, F., & Mazure, N. M. (2006) · Nature · doi:10.1038/nature04871 · Cited by 1,676
Definition of type I and type II photosensitized oxidation
Foote, C. S. (1991) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1991.tb02071.x · Cited by 1,248
5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma
Coupienne, I., Fettweis, G., Rubio, N., Agostinis, P., & Piette, J. (2011) · Photochemical & Photobiological Sciences · doi:10.1039/c1pp05213f · Cited by 91
Weijer, R., Broekgaarden, M., Krekorian, M., Alles, L. K., van Wijk, A. C., Mackaaij, C., Verheij, J., van der Wal, A. C., van Gulik, T. M., Storm, G., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.6490 · Cited by 67
Cited by
Stimuli-Responsive Polymer-Based Nanosystems for Cancer Theranostics
Wei, D., Sun, Y., Zhu, H., & Fu, Q. (2023) · ACS Nano · doi:10.1021/acsnano.3c06019 · Cited by 303
Thapa Magar, T. B., Shrestha, R., Gurung, P., Lim, J., & Kim, Y.-W. (2022) · Processes · doi:10.3390/pr10112215 · Cited by 8
Self-citation
Metadata
- Authors
- Sai, D. L., Lee, J., Nguyen, D. L., & Kim, Y.-P.
- Venue
- Experimental & Molecular Medicine
- Published
- 2021-04
- Volume
- 53
- Issue
- 4
- Pages
- 495-504
- ISSN
- 1226-3613 (ISSN-L)
- 2092-6413
- OpenAlex
- W3140383478
- Cited by
- 275
- References
- 7
- FWCI
- 21.56
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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