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Cited by 258

The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.

Memory and cognition in schizophrenia

Open access
Guo, J. Y., Ragland, J. D., Carter, C. S.·2019·Molecular Psychiatry

Abstract

Episodic memory deficits are consistently documented as a core aspect of cognitive dysfunction in schizophrenia patients, present from the onset of the illness and strongly associated with functional disability. Over the past decade, research using approaches from experimental cognitive neuroscience revealed disproportionate episodic memory impairments in schizophrenia (Sz) under high cognitive demand relational encoding conditions and relatively unimpaired performance under item-specific encoding conditions. These specific deficits in component processes of episodic memory reflect impaired activation and connectivity within specific elements of frontal-medial temporal lobe circuits, with a central role for the dorsolateral prefrontal cortex (DLPFC), relatively intact function of ventrolateral prefrontal cortex and variable results in the hippocampus. We propose that memory deficits can be understood within the broader context of cognitive deficits in Sz, where impaired DLPFC-related cognitive control has a broad impact across multiple cognitive domains. The therapeutic implications of these findings are discussed.

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Metadata

Authors
Guo, J. Y., Ragland, J. D., & Carter, C. S.
Venue
Molecular Psychiatry
Published
2018-09-21
Volume
24
Issue
5
Pages
633-642
ISSN
  • 1359-4184 (ISSN-L)
  • 1476-5578
OpenAlex
W2892233392
Cited by
258
References
120
FWCI
13.01
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Memory and cognition in schizophrenia. https://app.cochat.ai/papers/10.1038/s41380-018-0231-1
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Guo, J. Y., Ragland, J. D., & Carter, C. S. (2019). Memory and cognition in schizophrenia. Molecular Psychiatry. https://doi.org/10.1038/s41380-018-0231-1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.