Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions

The Epidemiology of Major Depressive Disorder: Results From the National Comorbidity Survey Replication (NCS-R)

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., Rush, A. J., Walters, E. E., & Wang, P. S. (2003) · JAMA · doi:10.1001/jama.289.23.3095 · Cited by 7,988

The World Health Report 2002 - Reducing Risks, Promoting Healthy Life

Available, N. A. N. (2003) · Education for Health · doi:10.1080/1357628031000116808 · Cited by 6,073

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Pellow, S., Chopin, P., File, S. E., & Briley, M. (1985) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(85)90031-7 · Cited by 5,822

Deep Brain Stimulation for Treatment-Resistant Depression

Mayberg, H. S., Lozano, A. M., Voon, V., McNeely, H. E., Seminowicz, D., Hamani, C., Schwalb, J. M., & Kennedy, S. H. (2005) · Neuron · doi:10.1016/j.neuron.2005.02.014 · Cited by 4,059

Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice

Trivedi, M. H., Rush, A. J., Wisniewski, S. R., Nierenberg, A. A., Warden, D., Ritz, L., Norquist, G., Howland, R. H., Lebowitz, B., McGrath, P. J., et al. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.1.28 · Cited by 3,879

Antidepressant effects of ketamine in depressed patients

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00230-9 · Cited by 3,856

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.

Zarate, C. A., Singh, J. B., Carlson, P. J., Brutsche, N. E., Ameli, R., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.8.856 · Cited by 3,766

A Neurotrophic Model for Stress-Related Mood Disorders

Duman, R. S., & Monteggia, L. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.013 · Cited by 3,375

The use of the elevated plus maze as an assay of anxiety-related behavior in rodents

Walf, A. A., & Frye, C. A. (2007) · Nature Protocols · doi:10.1038/nprot.2007.44 · Cited by 3,035

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Li, N., Lee, B., Liu, R.-J., Banasr, M., Dwyer, J. M., Iwata, M., Li, X.-Y., Aghajanian, G., & Duman, R. S. (2010) · Science · doi:10.1126/science.1190287 · Cited by 2,881

Brain‐Targeted Black Phosphorus‐Based Nanotherapeutic Platform for Enhanced Hypericin Delivery in Depression

Tan, H., Cao, K., Zhao, Y., Zhong, J., Deng, D., Pan, B., Zhang, J., Zhang, R., Wang, Z., Chen, T., et al. (2024) · Small · doi:10.1002/smll.202310608 · Cited by 16

Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches

Sokolov, A. V., & Schiöth, H. B. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02992-y · Cited by 16

Selecting antidepressants according to a drug-by-environment interaction: A comparison of fluoxetine and minocycline effects in mice living either in enriched or stressful conditions

Poggini, S., Bon, G. M., Golia, M. T., Albanese, N. C., Viglione, A., Poleggi, A., Limatola, C., Maggi, L., & Branchi, I. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113256 · Cited by 17

Brain circuit dysfunction in specific symptoms of depression

Lv, Q. Y., Chen, M., Li, Y., Yu, Y. W., & Liao, H. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15221 · Cited by 16

Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception

Qin, N., Zhao, Y.-R., Shi, W., Zhou, Z., Zou, K., Yu, C., Liu, X., Dong, Z.-H., Mao, Y., Zhou, C., et al. (2021) · Reproduction · doi:10.1530/rep-21-0175 · Cited by 15

School Climate, Cortical Structure, and Socioemotional Functioning: Associations across Family Income Levels

Hackman, D. A., Duan, L., McConnell, E. E., Lee, W. J., Beak, A. S., & Kraemer, D. J. M. (2022) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01833 · Cited by 16

Sex-Specific Brain Transcriptional Signatures in Human MDD and Their Correlates in Mouse Models of Depression

Touchant, M., & Labonté, B. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.845491 · Cited by 19

Adolescent neurodevelopment and psychopathology: The interplay between adversity exposure and genetic risk for accelerated brain ageing

Petrican, R., & Fornito, A. (2023) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2023.101229 · Cited by 16

Retrovirus-Derived RTL/SIRH: Their Diverse Roles in the Current Eutherian Developmental System and Contribution to Eutherian Evolution

Kaneko-Ishino, T., & Ishino, F. (2023) · Biomolecules · doi:10.3390/biom13101436 · Cited by 15

The Effect of the Low Glutamate Diet on the Reduction of Psychiatric Symptoms in Veterans With Gulf War Illness: A Pilot Randomized-Controlled Trial

Brandley, E. T., Kirkland, A. E., Baron, M. I., Baraniuk, J. N., & Holton, K. F. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.926688 · Cited by 15

The role of astrocytes in behaviors related to emotion and motivation

Shigetomi, E., & Koizumi, S. (2022) · Neuroscience Research · doi:10.1016/j.neures.2022.09.015 · Cited by 16

Unique Features of the Immune Response in BTBR Mice

Mutovina, A., Ayriyants, K. A., Mezhlumyan, E. V., Ryabushkina, Y. A., Litvinova, E. A., Bondar, N. P., Khantakova, J. N., & Reshetnikov, V. V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232415577 · Cited by 14

Quantification of Glutathione and Its Associated Spontaneous Neuronal Activity in Major Depressive Disorder and Obsessive-Compulsive Disorder

Lee, S. W., Kim, S., Chang, Y., Cha, H., Noeske, R., Choi, C., & Lee, S. J. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.08.018 · Cited by 14

Immune Activation in Pregnant Rats Affects Brain Glucose Consumption, Anxiety-like Behaviour and Recognition Memory in their Male Offspring

Guerrin, C. G. J., Shoji, A., Doorduin, J., & de Vries, E. F. J. (2022) · Molecular Imaging and Biology · doi:10.1007/s11307-022-01723-3 · Cited by 17

Transcriptome Alterations Caused by Social Defeat Stress of Various Durations in Mice and Its Relevance to Depression and Posttraumatic Stress Disorder in Humans: A Meta-Analysis

Reshetnikov, V. V., Kisaretova, P. E., & Bondar, N. P. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232213792 · Cited by 16

G protein-coupled receptors as targets for transformative neuropsychiatric therapeutics

Schmitz, G. P., & Roth, B. L. (2023) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00397.2022 · Cited by 13

Reviving: restoring depression-like behaviour through glial cell–derived neurotrophic factor treatment in the medial prefrontal cortex

Liu, Y., Zhou, X., Xue, K., Sun, R., Tang, Y., & Tang, C. (2024) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.230079 · Cited by 13

Sex-specific effects of ketogenic diet on anxiety-like behavior and neuroimmune response in C57Bl/6J mice

Kumar, M., Bhatt, B., Gusain, C., Mahajan, N., & Bishnoi, M. (2024) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2024.109591 · Cited by 15

C3aR in the medial prefrontal cortex modulates the susceptibility to LPS-induced depressive-like behaviors through glutamatergic neuronal excitability

Sun, R., Tang, M., Yang, D., Zhang, Y.-Y., Xu, Y.-H., Qiao, Y., Yu, B., Cao, S.-X., Wang, H., Huang, H.-Q., et al. (2024) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2024.102614 · Cited by 14

Excitatory projections from the nucleus reuniens to the medial prefrontal cortex modulate pain and depression-like behaviors in mice

Bao, S.-T., Rao, F., Cui, Y., Niu, Y., Cao, J., Xiao, C., & Zhou, C. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003170 · Cited by 13

A novel model of obesity prediction: Neurobehaviors as targets for treatment.

Satyal, M. K., Basso, J. C., Tegge, A. N., Metpally, A., & Bickel, W. K. (2021) · Behavioral Neuroscience · doi:10.1037/bne0000385 · Cited by 16

Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex

Bai, M., Yu, H., Chen, C., Xu, X., He, Y., Wang, Y., Tian, Y., Wu, Z., Lan, T., Li, Y., et al. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.136423 · Cited by 11

Potential Therapeutic Effects of NAMPT-Mediated NAD Biosynthesis in Depression In Vivo

Wang, J., Sun, R., Xia, L., Zhu, X., Zhang, Q., & Ye, Y. (2022) · Brain Sciences · doi:10.3390/brainsci12121699 · Cited by 14

A prefrontal–habenular circuitry regulates social fear behaviour

Tian, Y., Zheng, J., Zhu, X., Liu, X., Li, H., Wang, J., Yang, Q., Zeng, L., Shi, Z., Gong, M., et al. (2024) · Brain · doi:10.1093/brain/awae209 · Cited by 12

Juvenile social isolation immediately affects the synaptic activity and firing property of fast-spiking parvalbumin-expressing interneuron subtype in mouse medial prefrontal cortex

Okamura, K., Yoshino, H., Ogawa, Y., Yamamuro, K., Kimoto, S., Yamaguchi, Y., Nishihata, Y., Ikehara, M., Makinodan, M., Saito, Y., et al. (2022) · Cerebral Cortex · doi:10.1093/cercor/bhac294 · Cited by 13

Medial prefrontal cortical PPM1F alters depression‐related behaviors by modifying p300 activity via the AMPK signaling pathway

Liu, J., Meng, F., Wang, W., Wu, M., Zhang, Y., Cui, M., Qiu, C., Hu, F., Zhao, D., Wang, D., et al. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14293 · Cited by 11

Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway

Fu, A., Qiao, F., Feng, H., & Luo, Q. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114464 · Cited by 13

Effect of salidroside on neuroprotection and psychiatric sequelae during the COVID-19 pandemic: A review

Zhu, T., Liu, H., Gao, S., Jiang, N., Chen, D., & Xie, W. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115999 · Cited by 14

The N -methyl- d -aspartate receptor hypothesis of ketamine’s antidepressant action: evidence and controversies

Jiang, Y., Dong, Y., & Hu, H. (2024) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2023.0225 · Cited by 11

Transformations in prefrontal ensemble activity underlying rapid threat avoidance learning

Gabriel, C., Gupta, T. A., Sánchez-Fuentes, A., Zeidler, Z., Wilke, S. A., & DeNardo, L. A. (2025) · Current Biology · doi:10.1016/j.cub.2025.01.010 · Cited by 11

The neural basis underlying female vulnerability to depressive disorders

Kim, M., Kim, W., & Chung, C. (2023) · Animal Cells and Systems · doi:10.1080/19768354.2023.2276815 · Cited by 13

Effect of Sensory Deprivation of Nasal Respiratory on Behavior of C57BL/6J Mice

Zhu, Y., Ye, Y., Zhou, C., Sun, S., Zhang, J., Zhao, Z., Sun, T., Li, J., Yang, J., Li, W., et al. (2021) · Brain Sciences · doi:10.3390/brainsci11121626 · Cited by 11

Epinephrine levels decrease in responders after electroconvulsive therapy

Pollak, C., Maier, H. B., Moschny, N., Jahn, K., Bleich, S., Frieling, H., & Neyazi, A. (2021) · Journal of Neural Transmission · doi:10.1007/s00702-021-02420-1 · Cited by 10

The Neural Correlates of Chewing Gum—A Neuroimaging Review of Its Effects on Brain Activity

Chmiel, J., & Malinowska, A. (2025) · Brain Sciences · doi:10.3390/brainsci15060657 · Cited by 10

Similarities and differences in working memory and neurometabolism of obsessive-compulsive disorder and major depressive disorder

He, J., Yan, S., Song, Z., Lu, Q., Zhong, S., Lai, S., Wang, Y., Chen, G., Zhao, H., Chen, P., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.05.069 · Cited by 10

Node of Ranvier remodeling in chronic psychosocial stress and anxiety

Koskinen, M.-K., Laine, M. A., Abdollahzadeh, A., Gigliotta, A., Mazzini, G., Journée, S. H., Alenius, V., Trontti, K., Tohka, J., Hyytiä, P., et al. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01568-6 · Cited by 10

TREK-1 inhibition promotes synaptic plasticity in the prelimbic cortex

de Oliveira, J. F., Higa, G. S. V., Viana, F. J. C., Cruvinel, E., Carlos-Lima, E., Borges, F. S., Zampieri, T. T., Rebello, F. P., Ulrich, H., & Pasquale, R. D. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114652 · Cited by 11

Developmental exposure to arsenic reduces anxiety levels and leads to a depressive-like behavior in female offspring rats: Molecular changes in the prefrontal cortex

Bartos, M., Gallegos, C. E., Mónaco, N., Lencinas, I., Domínguez, S., Bras, C., Esandi, M. D. C., Bouzat, C., & Gumilar, F. (2024) · NeuroToxicology · doi:10.1016/j.neuro.2024.07.013 · Cited by 10

β2-Adrenoceptors in the Medial Prefrontal Cortex Excitatory Neurons Regulate Anxiety-like Behavior in Mice

Lei, Z., Lam, Y.-Y., Li, C.-H., Fu, Z., Ramkrishnan, A. S., Liu, S., & Li, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105578 · Cited by 10

Chronic Exposure to Environmentally Relevant Doses of Triphenyl Phosphate Induces Anxiety- and Depression-Like Behaviors in Mice via the Gut–Brain Axis

Dan, A., Yuan, J., Xie, P., Chen, J., Chen, C., Lin, Z., & Cai, Z. (2025) · Environmental Science & Technology · doi:10.1021/acs.est.5c03124 · Cited by 10

Mechanism-guided identification of antidepressant G protein-coupled receptor drug targets

Munguba, H., Arefin, A., Hasegawa, R., Posa, L., Romano, G. R., Peddada, T., Donatelle, A., Singh, A., Gutzeit, V. A., Vijay, A., et al. (2026) · Cell · doi:10.1016/j.cell.2026.04.006 · Cited by 10

Innate immune stimulation prevents the development of anxiety-like behaviors in chronically stressed mice

Shi, R., Liu, H., Tan, P., Hu, Z., Ma, Y., Ye, M., Gu, Y., Wang, Y., Ye, T., Gu, Y., et al. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.108950 · Cited by 9

Metabolic Fingerprints of Effective Fluoxetine Treatment in the Prefrontal Cortex of Chronically Socially Isolated Rats: Marker Candidates and Predictive Metabolites

Filipović, D., Inderhees, J., Korda, A. I., Tadic, P. R., Schwaninger, M., Inta, D., & Borgwardt, S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310957 · Cited by 9

Hallucinogenic potential: a review of psychoplastogens for the treatment of opioid use disorder

Hornick, M. G., & Stefanski, A. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1221719 · Cited by 9

Gray matter biomarkers for major depressive disorder and manic disorder using logistic regression

Kumar, M., Goyal, P., Sagar, R., & Kumaran, S. S. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.01.043 · Cited by 9

Acute manipulation of Drd1 neurons in the prefrontal cortex bidirectionally regulates anxiety and depression-like behaviors

Chen, H., Chen, J., & Lan, J. (2024) · Neuroscience Letters · doi:10.1016/j.neulet.2024.137805 · Cited by 9

Role of Prefrontal Cortex Circuitry in Maintaining Social Homeostasis

Lee, S., & Williams, Z. M. (2024) · Biological Psychiatry · doi:10.1016/j.biopsych.2024.07.007 · Cited by 10

Antidepressant activity of pharmacological and genetic deactivation of the small-conductance calcium-activated potassium channel subtype-3

Nashed, M. G., Waye, S., Hasan, S. M. N., Nguyen, D., Wiseman, M., Zhang, J., Lau, H., Dinesh, O. C., Raymond, R., Greig, I. R., et al. (2022) · Psychopharmacology · doi:10.1007/s00213-021-06045-w · Cited by 9

Exposure to chronic stress impairs the ability to cope with an acute challenge: Modulation by lurasidone treatment

Begni, V., Pisano, I., Marizzoni, M., Marchisella, F., Creutzberg, K. C., Rosa, F. D., Cattaneo, A., Gruca, P., Litwa, E., Papp, M., et al. (2022) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2022.06.005 · Cited by 9

An epigenetic mechanism of social isolation stress in adolescent female mice

Li, P., & Yan, Z. (2023) · Neurobiology of Stress · doi:10.1016/j.ynstr.2023.100601 · Cited by 8

1,2-Dichloroethane causes anxiety and cognitive dysfunction in mice by disturbing GABA metabolism and inhibiting the cAMP-PKA-CREB signaling pathway

Qin, Y., Huang, W., Wang, Z., Wang, C., Wang, C., Zhang, M., Wu, S., Wang, G., & Zhao, F. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116464 · Cited by 8

Neural Modulation Alteration to Positive and Negative Emotions in Depressed Patients: Insights from fMRI Using Positive/Negative Emotion Atlas

Feng, Y., Zeng, W., Xie, Y., Chen, H., Wang, L., Wang, Y., Yan, H., Zhang, K., Tao, R., Siok, W. T., et al. (2024) · Tomography · doi:10.3390/tomography10120144 · Cited by 8

Sex and Circadian Rhythm Dependent Behavioral Effects of Chronic Stress in Mice and Modulation of Clock Genes in the Prefrontal Cortex

Mingardi, J., Giovenzana, M., Nicosia, N., Misztak, P., Ieraci, A., & Musazzi, L. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136410 · Cited by 8

Environmental and genetic risk factors of depression converge on neuronal dysfunction driven by changes in cholesterol homeostasis

Oberst, P., Xu, N., Munguba, H., Zhang, C., Zhong, A., Zhou, T., Liston, C. M., Levitz, J., & Studer, L. (2025) · Developmental Cell · doi:10.1016/j.devcel.2025.08.011 · Cited by 8

Long-term chemogenetic activation of M1 glutamatergic neurons attenuates the behavioral and cognitive deficits caused by intracerebral hemorrhage

Ling, W., Cui, Y., Gao, J., Jiang, X., Wang, R. C., Tian, Y., Sheng, H., & Cui, J. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.04.083 · Cited by 8

Genetic Ablation of the Inducible Form of Nitric Oxide in Male Mice Disrupts Immature Neuron Survival in the Adult Dentate Gyrus

Fernandes, G. G., Costa, K. C. M., Scomparin, D. S., Freire, J. B., Guimarães, F. S., & Campos, A. C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.782831 · Cited by 8

Prefrontal reactivity to TMS perturbation as a toy model of mental health outcomes during the COVID-19 pandemic

Perellón‐Alfonso, R., Redondo‐Camós, M., Abellaneda‐Pérez, K., Cattaneo, G., Delgado‐Gallén, S., España‐Irla, G., Sánchez, J. S., Tormos, J. M., Pascual‐Leone, Á., & Bartrés‐Faz, D. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e10208 · Cited by 10

Sex-specific association between prenatal androgenization (second-to-fourth digit length ratio) and frontal brain volumes in adolescents

Lenz, B., Gerhardt, S., Boroumand-Jazi, R., Eichler, A., Buchholz, V. N., Fasching, P. A., Kornhuber, J., Banaschewski, T., Flor, H., Guldner, S., et al. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-022-01515-4 · Cited by 8

Effects of constant darkness on behaviour and physiology of male and female mice

Singh, D., Pandey, S., Ghosh, A., & Aich, P. (2023) · European Journal of Neuroscience · doi:10.1111/ejn.15972 · Cited by 8

Associations among brain-derived neurotrophic factor gene, peer relationships, and depression across early adolescence: Dynamic genetic effects

Yanmiao, C. A. O., Huici, F. A. N. G., Xinyue, Z. H. U., Ji, L., & ZHANG, W. (2023) · Acta Psychologica Sinica · doi:10.3724/sp.j.1041.2023.01620 · Cited by 8

Social environment enrichment alleviates anxiety-like behavior in mice: Involvement of the dopamine system

Wang, Q., Wang, Y., Tian, Y., Li, Y., Han, J., Tai, F., & Jia, R. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114687 · Cited by 10

Running exercise decreases microglial activation in the medial prefrontal cortex in an animal model of depression

Liu, S., Xiao, Q., Tang, J., Li, Y., Zhu, P., Liang, X., Huang, D., Liu, L., Deng, Y., Jiang, L. H., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.09.124 · Cited by 8

Corticotropin‐releasing factor signaling and its potential role in the prefrontal cortex‐dependent regulation of anxiety

Yang, X., & Geng, F. (2023) · Journal of Neuroscience Research · doi:10.1002/jnr.25238 · Cited by 9

Spatially resolved mapping of cells associated with human complex traitsPreprint

Song, L., Chen, W., Hou, J., Guo, M., & Yang, J. (2024) · medRxiv · doi:10.1101/2024.10.31.24316538 · Cited by 8

Perinatal omega-3 sex-selectively mitigates neuropsychiatric impacts of prenatal THC in the cortico-striatal-hippocampal circuit

Sarikahya, M. H., Cousineau, S. L., Felice, M. D., Szkudlarek, H. J., Lee, K., Doktor, A., Alcaide, A., DeVuono, M. V., Dembla, A., Wong, K., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03113-x · Cited by 9

Depression induced by low-frequency repetitive transcranial magnetic stimulation to ventral medial frontal cortex in monkeys

Nakamura, S., Kishimoto, Y., Sekino, M., Nakamura, M., & Tsutsui, K. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114168 · Cited by 7

Effective connectivity between deep brain stimulation targets in individuals with treatment-resistant depression

Amiri, S., Arbabi, M., Rahimi, M., Parvaresh, M., & Mirbagheri, M. M. (2023) · Brain Communications · doi:10.1093/braincomms/fcad256 · Cited by 7

Structural and Functional Brain Changes After Glucocorticoid Therapy in Thyroid-Associated Ophthalmopathy

Wu, Q., Zhou, J., Fang, W., Jiang, W., Pu, X., Chen, H., Xu, X., Hu, H., & Wu, F. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad626 · Cited by 7

Coenzyme Q10 and vitamin E alleviate heat stress-induced mood disturbances in male mice: Modulation of inflammatory pathways and the HPA axis

Mahmoudi, J., Kazmi, S., Vatandoust, S. M., Athari, S. Z., Sadigh‐Eteghad, S., Morsali, S., Bahari, L., Ahmadi, M., Hosseini, L., & Farajdokht, F. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.115259 · Cited by 7

Alteration of Oxidative stress and apoptotic markers alterations in the rat prefrontal cortex influence behavioral response induced by cisplatin and N-acetylcysteine in the tail suspension test.

Vuković, R., Selaković, D., Katanić-Stanković, J., Kumburovic, I., Jovicic, N., & Rosic, G. (2021) · Journal of Integrative Neuroscience · doi:10.31083/j.jin2003076 · Cited by 8

Hearing Loss Increases Inhibitory Effects of Prefrontal Cortex Stimulation on Sound Evoked Activity in Medial Geniculate Nucleus

de Vis, C., Barry, K. M., & Mulders, W. H. A. M. (2022) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2022.840368 · Cited by 7

Altered Metabolism of the Microbiota–Gut–Brain Axis Is Linked With Comorbid Anxiety in Fecal Recipient Mice of Myasthenia Gravis

Zhang, H., Li, Y., Zheng, P., Wu, J., Huang, Y., Tan, X., Hu, X., Wen, L., Xie, P., Zhou, X., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.804537 · Cited by 9

Clinical features and power spectral entropy of electroencephalography in Wilson's disease with dystonia

Zhang, S., Liu, A., Zhou, Z., Huang, Z., Cheng, J., Chen, D., Zhong, Q., Yu, Q., Peng, Z., & Hong, M. (2022) · Brain and Behavior · doi:10.1002/brb3.2791 · Cited by 7

Age-related changes in glutamic acid decarboxylase 1 gene expression in the medial prefrontal cortex and ventral hippocampus of fear-potentiated rats subjected to isolation stress

Sirchi, M. M., Motaghi, S., Hosseininasab, N. S., Abbasnejad, M., Esmaeili‐Mahani, S., & Sepehri, G. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114630 · Cited by 7

Quantitative proteomic analysis of cortex in the depressive-like behavior of rats induced by the simulated complex space environment

Min, R., Chen, Z., Wang, Y., Deng, Z., Zhang, Y., & Deng, Y. (2021) · Journal of Proteomics · doi:10.1016/j.jprot.2021.104144 · Cited by 7

Astrocytic dopamine D1 receptor modulates glutamatergic transmission and synaptic plasticity in the prefrontal cortex through d-serine

Yin, Y., Hu, J., Wu, H., Yang, X., Qi, J., Huang, L., Luo, Z.-Y., Jin, S., Hu, N.-Y., Luo, Z.-C., et al. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.07.034 · Cited by 7

How dopamine guides our social world

Padilla-Coreano, N., & Martínez-Rivera, F. J. (2025) · Pharmacological Reviews · doi:10.1016/j.pharmr.2025.100085 · Cited by 6

Disrupted synapses: prefrontal cortex-reward circuit dysfunction in stress-induced depression-like behaviors

Mahmud, A., & Karaman, M. A. (2026) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2026.1843871 · Cited by 7

Predictors for delayed awakening in adult glioma patients receiving awake craniotomy under monitored anesthesia care

Lin, H.-T., Lin, C.-M., Wu, Y.-Y., Chang, W.-H., Wei, K., Chen, Y., Chen, P., Liu, F.-C., & Chen, K. (2023) · Journal of Neuro-Oncology · doi:10.1007/s11060-023-04494-1 · Cited by 7

Functional and morphological adaptation of medial prefrontal corticotropin releasing factor receptor 1-expressing neurons in male mice following chronic ethanol exposure

Patel, R. R., Gandhi, P. J., Spencer, K. S. R., Salem, N. A., Erikson, C. M., Borgonetti, V., Vlkolinský, R., Rodriguez, L., Nadav, T., Bajo, M., et al. (2024) · Neurobiology of Stress · doi:10.1016/j.ynstr.2024.100657 · Cited by 6

Transiently elevated expression of different forms of brain-derived neurotrophic factor in the neonatal medial prefrontal cortex affected anxiety and depressive-like behaviors in adolescence

Lanshakov, D. A., Shaburova, E. V., Sukhareva, E., Bulygina, V. V., Drozd, U. S., Larionova, I., Gerashchenko, T. S., Шнайдер, Т. А., Denisov, E. V., & Kalinina, T. S. (2024) · PeerJ · doi:10.7717/peerj.18465 · Cited by 6

Optogenetic Dissection of Neural Circuits Underlying Stress-Induced Mood Disorders

Liu, Q., Zhang, Z., & Zhang, W. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.600999 · Cited by 9

Over-representation of fundamental decision variables in the prefrontal cortex underlies decision bias

Ohnuki, T., Osako, Y., Manabe, H., Sakurai, Y., & Hirokawa, J. (2021) · Neuroscience Research · doi:10.1016/j.neures.2021.07.002 · Cited by 4

DNA Methylation Markers and Prediction Model for Depression and Their Contribution for Breast Cancer Risk

Wang, N., Sun, J. Y., Pang, T., Zheng, H., Liang, F., He, X., Tang, D., Yu, T., Xiong, J., & Chang, S. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.845212 · Cited by 7

The involvement of Notch1 signaling pathway in mid-aged female rats under chronic restraint stress

Shen, J., Lin, L., Liao, L., Liang, W., Yang, X., Lin, K., Ke, L. W., Zhang, L., Kang, J., Ding, S., et al. (2020) · Neuroscience Letters · doi:10.1016/j.neulet.2020.135313 · Cited by 6

Prefrontal contributions to mental resilience: Lessons from rodent studies of stress and antidepressant actions

Shinohara, R., & Furuyashiki, T. (2022) · Neuroscience Research · doi:10.1016/j.neures.2022.12.015 · Cited by 7

Chronic Alcohol Drinking Drives Sex-Specific Differences in Affective Behavior and Medial Prefrontal Cortex Activity in CRF1:Cre:tdTomato Transgenic Rats

Quadir, S. G., Arleth, G., Cone, M. G., High, M. W., Ramage, M. C., Effinger, D. P., Sanchez, M. E., & Herman, M. A. (2023) · eNeuro · doi:10.1523/eneuro.0055-23.2023 · Cited by 6

In vivo labeling and quantitative imaging of neuronal populations using MRI

Li, S., Xu, X., Li, C., Xu, Z., Wu, K., Ye, Q., Zhang, Y., Jiang, X., Cang, C., Tian, C., et al. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120374 · Cited by 6

Global Cerebral Ischemia-induced Depression Accompanies Alteration of Neuronal Excitability in the Infralimbic Cortex Layer 2/3 Pyramidal Neurons

Jang, D. C., Choi, S., Chung, G., & Kim, S. K. (2023) · Experimental Neurobiology · doi:10.5607/en23017 · Cited by 6

Advances in optogenetic studies of depressive-like behaviors and underlying neural circuit mechanisms

Lin, S., Du, Y., Xia, Y., Xie, Y., Xiao, L., & Wang, G. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.950910 · Cited by 7

Editorial: Neural circuits and neuroendocrine mechanisms of depression and premenstrual dysphoric disorder: towards precise targets for translational medicine and drug development, volume II

Wei, S., Tang, Y., Wang, F., Wang, Y., & Geng, X. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1216689 · Cited by 6

Different prefrontal cortex activity patterns in bipolar and unipolar depression during verbal fluency tasks based on functional near infrared spectroscopy study

Mou, L., Shen, Y., Wu, B., Zhang, C., Zhu, J., Tan, Q., Zhang, X., Wang, Z., & Shen, Z. (2025) · Scientific Reports · doi:10.1038/s41598-025-05896-z · Cited by 5

Discovering the Causal Structure of the Hamilton Rating Scale for Depression Using Causal Discovery

Wang, L., Chignell, M., Jiang, H., Lokuge, S., Mason, G. E., Fotinos, K., & Katzman, M. A. (2021) · IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI ...) · doi:10.1109/bhi50953.2021.9508538 · Cited by 5

Functional Genomics Analysis to Disentangle the Role of Genetic Variants in Major Depression

Pérez‐Granado, J., Piñero, J., Medina-Rivera, A., & Furlong, L. I. (2022) · Genes · doi:10.3390/genes13071259 · Cited by 5

Transcranial direct current stimulation of the prefrontal cortex improves depression-like behaviors in rats with Parkinson's disease

Zhang, L., Guo, Y., Liu, J., Li, L., Wang, Y., Wu, X., Bai, Y., Li, J., Zhang, Q., & Hui, Y. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148649 · Cited by 5

Dissociation and other trauma symptomatology are linked to imbalance in the competing neurobehavioral decision systems

Basso, J. C., Satyal, M. K., McKee, K. L., Lynn, S., Gyamfi, D., & Bickel, W. K. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1317088 · Cited by 5

Neurobiological traces of grief: Examining the impact of offspring loss after birth on rat mothers’ brain and stress-coping behavior in the first week postpartum

Demarchi, L., Sanson, A., & Bosch, O. J. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104065 · Cited by 5

Stress and reproduction in amphibians

Carr, J. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-16020-2.00002-4 · Cited by 5

Interplay of miRNAs and molecular pathways in spaceflight‐induced depression: Insights from a rat model using simulated complex space environment

Rasheed, M., Tahir, R. A., Maazouzi, M., Wang, H., Li, Y., Chen, Z., & Deng, Y. (2024) · The FASEB Journal · doi:10.1096/fj.202400420rr · Cited by 5

PACAP/VIP in the prefrontal cortex mediates the rapid antidepressant effects of zhizichi decoction

Ren, L., Fan, Y., Luo, H., Hu, J., & Hu, J. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118638 · Cited by 5

Neural Circuits Underlying the Pathophysiology of Major Depression

Amidfar, M., & Kim, Y. (2022) · Neuromethods · doi:10.1007/978-1-0716-2083-0_3

Targeting the Neuronal Activity of Prefrontal Cortex: New Directions for the Therapy of Depression

Zhou, X., Bao, W.-D., Liu, D., & Zhu, L. (2019) · Current Neuropharmacology · doi:10.2174/1570159x17666191101124017 · Cited by 22

Optogenetic Stimulation of Drd1 Expressing Neurons Produces Rapid and Long-Lasting Antidepressant EffectsPreprint

Hare, B. D., Liu, R. J., Shinohara, R., Pothula, S., Dileone, R., & Duman, R. S. (2018) · SSRN Electronic Journal · doi:10.2139/ssrn.3155673

W31. KETAMINE AND ELECTROCONVULSIVE THERAPY DEPRESSION TREATMENTS ALTER ISOFORM- AND CELL TYPE-SPECIFIC TRANSCRIPTOMES IN THE MOUSE PREFRONTAL FRONTAL CORTEX

Chehimi, S. N., Crist, R. C., Batterman, A. I., Nguyen, D. P., Williams, A. A., Keck, T. M., Berrettini, W. H., Buono, R. J., Ferraro, T. N., & Reiner, B. C. (2024) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2024.08.240

Advances in neurotransmitter-mediated prefrontal circuitry in depression

Li, S., Gao, M., Mou, Z., Zhang, H., Wang, Y., & Zhang, Y. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111475 · Cited by 12