The NIH ECHO program: investigating how early environmental influences affect child health
Open accessAbstract
The ECHO Program has two major components, pediatric cohorts — focusing on observational research — and the IDeA States Pediatric Clinical Trials Network (ISPCTN) — focusing on interven-tional research. The program ’ s mission is to enhance the health of children for generations to come. ECHO ’ s goals are to (1) enable high-impact research evidence that will inform clinical practices, policies, and programs for child health and development; and (2) establish a national data platform and biorepository for the scienti fi c community. This article discusses the observational research component of ECHO and introduces a series of three reviews 1 – 3 appearing in this issue or forthcoming, each covering a different aspect of the ECHO Program. ECHO supports multiple synergistic, longitudinal studies to investigate how environmental exposures in early life — including physical, chemical, social, behavioral, biological, natural, and built environments — affect child health and development. ECHO science focuses on fi ve key pediatric outcomes that have a high public health impact: (1) pre-, peri-, and postnatal outcomes; (2) upper and lower airway conditions; (3) obesity; (4) neurodevelop-ment; and (5) positive health. ECHO uses a collaborative team science approach to children ’ s health research. 1 NIH designed the ECHO pediatric cohorts by leveraging existing longitudinal birth cohorts, and supporting expansion of recruit-ment and continued follow-up of pregnant women and
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Cites
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- Authors
- Blaisdell, C. J., Park, C., Hanspal, M., Roary, M., Arteaga, S. S., Laessig, S., Luetkemeier, E., Gillman, M. W., & Outcomes, O. B. O. P. C. F. E. I. O. C. H.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Blaisdell, Carol J.
- Venue
- Pediatric Research
- Published
- 2021-06-15
- Volume
- 92
- Issue
- 5
- Pages
- 1215-1216
- ISSN
- 0031-3998 (ISSN-L)
- 1530-0447
- PMC
- PMC8204611
- OpenAlex
- W3170640175
- Semantic Scholar
- a93cb42476d0b59aaf6bfe3147ec223b8fdc8958
- Cited by
- 121
- References
- 11
- Citations by year
- 2026: 27 · 2025: 21 · 2024: 25 · 2023: 37 · 2022: 10 · 2021: 1
- FWCI
- 7.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Pediatric Research (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Environmental Health Sciences
- Duke Clinical Research Institute
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Health Sciences › Health Professions › General Health Professions › Child and Adolescent Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Keywords
- ECHO program, pediatric cohort, observational studies, intervention research, child health and development, biorepository
- MeSH terms
- Child Health, Child, Environmental Exposure, Environmental Health, Humans
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