The DOI matches its Crossref record; 159 of the 159 references it cites were found in a registry or an index.
Overview of lethal human coronaviruses
Open accessAbstract
Coronavirus infections of multiple origins have spread to date worldwide, causing severe respiratory diseases. Seven coronaviruses that infect humans have been identified: HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, SARS-CoV, MERS-CoV, and SARS-CoV-2. Among them, SARS-CoV and MERS-CoV caused outbreaks in 2002 and 2012, respectively. SARS-CoV-2 (COVID-19) is the most recently discovered. It has created a severe worldwide outbreak beginning in late 2019, leading to date to over 4 million cases globally. Viruses are genetically simple, yet highly diverse. However, the recent outbreaks of SARS-CoV and MERS-CoV, and the ongoing outbreak of SARS-CoV-2, indicate that there remains a long way to go to identify and develop specific therapeutic treatments. Only after gaining a better understanding of their pathogenic mechanisms can we minimize viral pandemics. This paper mainly focuses on SARS-CoV, MERS-CoV, and SARS-CoV-2. Here, recent studies are summarized and reviewed, with a focus on virus–host interactions, vaccine-based and drug-targeted therapies, and the development of new approaches for clinical diagnosis and treatment.
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1 retracted
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RetractedClinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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A novel coronavirus from patients with pneumonia in China, 2019
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A pneumonia outbreak associated with a new coronavirus of probable bat origin
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La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
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Cited by
Zou, X., Chen, K., Zou, J., Han, P., Hao, J., & Han, Z. (2020) · Frontiers of Medicine · doi:10.1007/s11684-020-0754-0 · Cited by 2,287
Meng, F., Xu, R., Wang, S., Xu, Z., Zhang, C., Li, Y., Yang, T., Shi, L., Fu, J., Jiang, T., et al. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00286-5 · Cited by 323
Self-citationShi, L., Huang, H., Lu, X., Yan, X., Jiang, X., Xu, R., Wang, S., Zhang, C., Yuan, X., Xu, Z., et al. (2021) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-021-00488-5 · Cited by 283
Self-citationViral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations
Xu, J.-Q., Zhang, W.-Y., Fu, J.-J., Fang, X.-Z., Gao, C.-G., Li, C., Yao, L., Li, Q.-L., Yang, X.-B., Ren, L.-H., et al. (2024) · Military Medical Research · doi:10.1186/s40779-024-00581-0 · Cited by 37
Metadata
- Authors
- Chen, B., Tian, E.-K., He, B., Tian, L., Han, R., Wang, S., Xiang, Q., Zhang, S., El Arnaout, T., & Cheng, W.
- Venue
- Signal Transduction and Targeted Therapy
- Published
- 2020-06-10
- Volume
- 5
- Issue
- 1
- Pages
- 89-89
- ISSN
- 2059-3635 (ISSN-L)
- OpenAlex
- W3034883465
- Cited by
- 300
- References
- 159
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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