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Tassinari, M., Richter, S. N., & Gandellini, P. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab127 · Cited by 82 · see citing works

Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands

Pirota, V., Nadai, M., Doria, F., & Richter, S. N. (2019) · Molecules · doi:10.3390/molecules24030426 · Cited by 83 · see citing works

Neuroprotection by Walnut-Derived Peptides through Autophagy Promotion via Akt/mTOR Signaling Pathway against Oxidative Stress in PC12 Cells

Zhao, F., Wang, J., Lu, H., Li, F., Qin, H., Liu, C., & Min, W. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b08252 · Cited by 77 · see citing works

Human MYC G-quadruplex: From discovery to a cancer therapeutic target

Wang, W., Hu, S., Gu, Y., Yan, Y., Stovall, D. B., Li, D., & Sui, G. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2020.188410 · Cited by 76 · see citing works

SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction

Lavigne, M., Helynck, O., Rigolet, P., Boudria-Souilah, R., Nowakowski, M., Baron, B., Brûlé, S., Hoos, S., Raynal, B. D. E., Guittat, L., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab571 · Cited by 71 · see citing works

Targeting c-MYC G-Quadruplexes for Cancer Treatment with Small Molecules

Thumpati, P., Rai, S. N., Prajapati, C., Ramakrishna, K., & Singh, S. K. (2025) · Scientia Pharmaceutica · doi:10.3390/scipharm93010006 · Cited by 69 · see citing works

Crosstalk between G-quadruplex and ROS

Wu, S., Jiang, L., Lei, L., Fu, C., Huang, J., Hu, Y., Dong, Y., Chen, J., & Zeng, Q. (2023) · Cell Death & Disease · doi:10.1038/s41419-023-05562-0 · Cited by 69 · see citing works

Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine

Wang, K., Liu, Y., Li, J., Xiao, C., Wang, Y., Gu, W., Li, Y., Xia, Y., Yan, T., Yang, M.-H., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33761-4 · Cited by 64 · see citing works

G-quadruplex resolution: From molecular mechanisms to physiological relevance

Sato, K., & Knipscheer, P. (2023) · DNA repair · doi:10.1016/j.dnarep.2023.103552 · Cited by 64 · see citing works

A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression

Deiana, M., Castán, J. M. A., Josse, P., Kahsay, A. G., Sánchez, D. P., Morice, K., Gillet, N., Ravindranath, R., Patel, A. K., Sengupta, P., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad365 · Cited by 63 · see citing works

Specific Recognition of Promoter G-Quadruplex DNAs by Small Molecule Ligands and Light-up Probes

Dhamodharan, V., & Pradeepkumar, P. I. (2019) · ACS Chemical Biology · doi:10.1021/acschembio.9b00475 · Cited by 59 · see citing works

Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition

Liu, W.-T., Lin, C., Wu, G., Dai, J., Chang, T.-C., & Yang, D. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz1015 · Cited by 57 · see citing works

Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models.

Ahmed, A., Angell, R., Oxenford, S., Worthington, J., Williams, N., Barton, N., Fowler, T. G., O'Flynn, D. E., Sunose, M., McConville, M., et al. (2020) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.0c00317 · Cited by 50 · see citing works

Quantitative Detection of G‐Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination

Liu, L., Liu, W., Wang, K., Zhu, B., Xia, X., Ji, L., & Mao, Z. (2020) · Angewandte Chemie · doi:10.1002/ange.202002422 · Cited by 56 · see citing works

Targeting specific DNA G-quadruplexes with CRISPR-guided G-quadruplex-binding proteins and ligands

Qin, G., Liu, Z., Yang, J., Liao, X., Zhao, C., Ren, J., & Qu, X. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01448-1 · Cited by 55 · see citing works

Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in Solution

Dickerhoff, J., Brundridge, N. M., McLuckey, S. A., & Yang, D. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c01508 · Cited by 53 · see citing works

RTEL1 influences the abundance and localization of TERRA RNA

Ghisays, F., Garzia, A., Wang, H., Canasto‐Chibuque, C., Hohl, M., Savage, S. A., Tuschl, T., & Petrini, J. H. J. (2021) · Nature Communications · doi:10.1038/s41467-021-23299-2 · Cited by 53 · see citing works

G-Quadruplexes in c-MYC Promoter as Targets for Cancer Therapy

Bahls, B., Aljnadi, I. M., Emídio, R. M., Mendes, E., & Paulo, A. (2023) · Biomedicines · doi:10.3390/biomedicines11030969 · Cited by 48 · see citing works

Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives

Pelliccia, S., Amato, J., Capasso, D., Gaetano, S. D., Massarotti, A., Piccolo, M., Irace, C., Tron, G. C., Pagano, B., Randazzo, A., et al. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b00262 · Cited by 52 · see citing works

Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes

Ray, S., Tillo, D., Boer, R. E., Assad, N., Barshai, M., Wu, G., Orenstein, Y., Yang, D., Schneekloth, J. S., & Vinson, C. (2020) · ACS Chemical Biology · doi:10.1021/acschembio.9b00934 · Cited by 51 · see citing works

Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model

Tassinari, M., Zuffo, M., Nadai, M., Pirota, V., Montalvo, A. C. S., Doria, F., Freccero, M., & Richter, S. N. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa186 · Cited by 50 · see citing works

G-quadruplex DNA and RNA: Their roles in regulation of DNA replication and other biological functions

Masai, H., & Tanaka, T. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.05.132 · Cited by 50 · see citing works

Turning Up the Heat on MYC: Progress in Small-Molecule Inhibitors

Truica, M. I., Burns, M. C., Han, H., & Abdulkadir, S. A. (2020) · Cancer Research · doi:10.1158/0008-5472.can-20-2959 · Cited by 50 · see citing works

Major Achievements in the Design of Quadruplex-Interactive Small Molecules

Mendes, E., Aljnadi, I. M., Bahls, B., Victor, B., & Paulo, A. (2022) · Pharmaceuticals · doi:10.3390/ph15030300 · Cited by 43 · see citing works

Duplex formation in a G-quadruplex bulge

Nguyen, T. Q. N., Lim, K. W., & Phan, A. T. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa738 · Cited by 48 · see citing works

Solution Structure of Ternary Complex of Berberine Bound to a dGMP–Fill-In Vacancy G-Quadruplex Formed in the PDGFR-β Promoter

Wang, K., Dickerhoff, J., & Yang, D. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.1c06200 · Cited by 46 · see citing works

Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes

Kumar, R., Chand, K., Bhowmik, S., Das, R. N., Bhattacharjee, S., Hedenström, M., & Chorell, E. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz1205 · Cited by 46 · see citing works

Selectivity and Targeting of G‐Quadruplex Binders Activated by Adaptive Binding and Controlled by Chemical Kinetics

Zhu, B., He, J., Liu, W., Xia, X. Y., Liu, L., Liang, B., Yao, H., Liu, B., Ji, L., & Mao, Z. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202104624 · Cited by 44 · see citing works

Comprehensive analysis of intramolecular G-quadruplex structures: furthering the understanding of their formalism

Farag, M., & Mouawad, L. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae182 · Cited by 43 · see citing works

Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length

Dickerhoff, J., Onel, B., Chen, L., Chen, Y., & Yang, D. (2019) · ACS Omega · doi:10.1021/acsomega.8b03580 · Cited by 43 · see citing works

Spiropyran in Situ Switching: A Real-Time Fluorescence Strategy for Tracking DNA G-Quadruplexes in Live Cells

Li, J., Yin, X., Li, B., Li, X., Pan, Y., Li, J., & Guo, Y. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b00436 · Cited by 42 · see citing works

Targeting MYCN in Molecularly Defined Malignant Brain Tumors

Borgenvik, A., Čančer, M., Hutter, S., & Swartling, F. J. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2020.626751 · Cited by 42 · see citing works

A Small Molecule Stabilizer of the MYC G4-Quadruplex Induces Endoplasmic Reticulum Stress, Senescence and Pyroptosis in Multiple Myeloma

Gaikwad, S. M., Phyo, Z. H., Quintanilla-Artega, A., Gorjifard, S., Calabrese, D. R., Connors, D. E., Huang, J. L., Michalowski, A. M., Zhang, S., Liu, Z.-G., et al. (2020) · Cancers · doi:10.3390/cancers12102952 · Cited by 40 · see citing works

A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA

Deiana, M., Chand, K., Jamroškovič, J., Das, R. N., Obi, I. R., Chorell, E., & Sabouri, N. (2020) · Nanoscale · doi:10.1039/d0nr03404e · Cited by 39 · see citing works

Targeting Transcription Factors in Cancer: From “Undruggable” to “Druggable”

Tao, Z., & Wu, X. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2815-7_9 · Cited by 37 · see citing works

MYC the oncogene from hell: Novel opportunities for cancer therapy

Papadimitropoulou, A., Makri, M., & Zoidis, G. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.116194 · Cited by 38 · see citing works

Coexistence of two quadruplex–duplex hybrids in the PIM1 gene

Tan, D. J. Y., Winnerdy, F. R., Lim, K. W., & Phan, A. T. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa752 · Cited by 37 · see citing works

Parallel G-quadruplexes recruit the HSV-1 transcription factor ICP4 to promote viral transcription in herpes virus-infected human cells

Frasson, I., Soldà, P., Nadai, M., Lago, S., & Richter, S. N. (2021) · Communications Biology · doi:10.1038/s42003-021-02035-y · Cited by 37 · see citing works

Role of c-Myc in lung cancer: Progress, challenges, and prospects

Wallbillich, N. J., & Lu, H. (2023) · Chinese Medical Journal - Pulmonary and Critical Care Medicine · doi:10.1016/j.pccm.2023.07.001 · Cited by 36 · see citing works

Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry

Litovchick, A., Xia, T., Monteiro, M. I., Kennedy, K. M., Guié, M.-A., Zhang, Y., Clark, M., & Keefe, A. D. (2019) · Molecules · doi:10.3390/molecules24102026 · Cited by 36 · see citing works

G-Quadruplexes in Human Telomere: Structures, Properties, and Applications

Xu, Y., & Komiyama, M. (2023) · Molecules · doi:10.3390/molecules29010174 · Cited by 28 · see citing works

A Rationally Designed Azobenzene Photoswitch for DNA G‐Quadruplex Regulation in Live Cells

Dudek, M., López‐Pacios, L., Sabouri, N., Nogueira, J. J., Martínez‐Fernández, L., & Deiana, M. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202413000 · Cited by 36 · see citing works

Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA

Dickerhoff, J., Warnecke, K. R., Wang, K., Deng, N., & Yang, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910801 · Cited by 34 · see citing works

Insights from Binding on Quadruplex Selective Carbazole Ligands

Müller, D., Saha, P., Panda, D., Dash, J., & Schwalbe, H. (2021) · Chemistry · doi:10.1002/chem.202101866 · Cited by 21 · see citing works

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

Deiana, M., Obi, I., Andréasson, M., Tamilselvi, S., Chand, K., Chorell, E., & Sabouri, N. (2021) · ACS Chemical Biology · doi:10.1021/acschembio.1c00134 · Cited by 24 · see citing works

The Myc Family and the Metastasis Suppressor NDRG1: Targeting Key Molecular Interactions with Innovative Therapeutics

Deng, Z., & Richardson, D. R. (2023) · Pharmacological Reviews · doi:10.1124/pharmrev.122.000795 · Cited by 32 · see citing works

Visualization of ligand-induced c-MYC duplex–quadruplex transition and direct exploration of the altered c-MYC DNA-protein interactions in cells

Yuan, J., Tu, J.-L., Liu, G., Chen, X., Huang, Z.-S., Chen, S.-B., & Tan, J. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac245 · Cited by 31 · see citing works

The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer

Ahmed, A., Greenhalf, W., Palmer, D., Williams, N., Worthington, J., Arshad, T., Haider, S., Alexandrou, E., Guneri, D., Waller, Z., et al. (2023) · Molecules · doi:10.3390/molecules28062452 · Cited by 22 · see citing works

G‐Quadruplex‐Binding Small Molecule Induces Synthetic Lethality in Breast Cancer Cells by Inhibiting c‐MYC and BCL2 Expression

Paul, R., Das, T., Debnath, M., Chauhan, A. K., & Dash, J. (2019) · ChemBioChem · doi:10.1002/cbic.201900534 · Cited by 31 · see citing works

Structured Waters Mediate Small Molecule Binding to G-Quadruplex Nucleic Acids

Neidle, S. (2021) · Pharmaceuticals · doi:10.3390/ph15010007 · Cited by 29 · see citing works

Ligands of G-quadruplex nucleic acids

Andreeva, D. V., Tikhomirov, A. S., & Shchekotikhin, A. E. (2020) · Russian Chemical Reviews · doi:10.1070/rcr4968 · Cited by 30 · see citing works

Targeting a noncanonical, hairpin-containing G-quadruplex structure from the MYCN gene

Yang, M., Carter, S., Parmar, S., Bume, D. D., Calabrese, D. R., Liang, X., Yazdani, K., Xu, M., Liu, Z., Thiele, C. J., et al. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab594 · Cited by 30 · see citing works

Targeting the RNA G-Quadruplex and Protein Interactome for Antiviral Therapy

Zhai, L.-Y., Liu, J.-F., Zhao, J.-J., Su, A.-M., Xi, X., & Hou, X. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c00649 · Cited by 30 · see citing works

Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling

Ahmed, A., Chen, S., Roman-Escorza, M., Angell, R., Oxenford, S., Mcconville, M., Barton, N., Sunose, M., Neidle, D. M., Haider, S., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-54080-2 · Cited by 25 · see citing works

G4detector: Convolutional Neural Network to Predict DNA G-Quadruplexes

Barshai, M., Aubert, A., & Orenstein, Y. (2021) · IEEE/ACM Transactions on Computational Biology & Bioinformatics · doi:10.1109/tcbb.2021.3073595 · Cited by 22 · see citing works

Spatial Matching Selectivity and Solution Structure of Organic–Metal Hybrid to Quadruplex–Duplex Hybrid

Liu, L., Wang, K., Liu, W., Zeng, Y., Hou, M., Yang, J., & Mao, Z. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202106256 · Cited by 29 · see citing works

Cationic helicenes as selective G4 DNA binders and optical probes for cellular imaging

Summers, P. A., Thomas, A. P., Kench, T., Vannier, J., Kuimova, M. K., & Vilar, R. (2021) · Chemical Science · doi:10.1039/d1sc04567a · Cited by 29 · see citing works

A Phenotypic Approach to the Discovery of Potent G-Quadruplex Targeted Drugs

Neidle, S. (2024) · Molecules · doi:10.3390/molecules29153653 · Cited by 27 · see citing works

Structural insights of the conserved “priming loop” of hepatitis B virus pre-genomic RNA

LeBlanc, R. M., Kasprzak, W. K., Longhini, A. P., Olenginski, L. T., Abulwerdi, F. A., Ginocchio, S., Shields, B., Nyman, J., Svirydava, M., Vecchio, C. D., et al. (2021) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2021.1934544 · Cited by 26 · see citing works

Parallel G-Quadruplex DNA Structures from Nuclear and Mitochondrial Genomes Trigger Emission Enhancement in a Nonfluorescent Nano-aggregated Fluorine–Boron-Based Dye

Deiana, M., Chand, K., Chorell, E., & Sabouri, N. (2023) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.2c03301 · Cited by 26 · see citing works

Insights into the Small Molecule Targeting of Biologically Relevant G-Quadruplexes: An Overview of NMR and Crystal Structures

Criscuolo, A., Napolitano, E., Riccardi, C., Musumeci, D., Platella, C., & Montesarchio, D. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14112361 · Cited by 25 · see citing works

An Octahedral Cobalt(III) Complex with Axial NH3 Ligands that Templates and Selectively Stabilises G‐quadruplex DNA

Rühl, C. L., Lim, A. H. M., Kench, T., Mann, D. J., & Vilar, R. (2019) · Chemistry - A European Journal · doi:10.1002/chem.201901569 · Cited by 24 · see citing works

Chemically modified CRISPR-Cas9 enables targeting of individual G-quadruplex and i-motif structures, revealing ligand-dependent transcriptional perturbation

Nuccio, S. P., Cadoni, E., Nikoloudaki, R., Galli, S., Ler, A.-J., Sanchez-Cabanillas, C., Maher, T. E., Fan, E., Guneri, D., Flint, G., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-67074-z · Cited by 22 · see citing works

Frontiers in G‐Quadruplex therapeutics in cancer: Selection of small molecules, peptides and aptamers

Banerjee, N., Panda, S., & Chatterjee, S. (2021) · Chemical Biology and Drug Design · doi:10.1111/cbdd.13910 · Cited by 19 · see citing works

Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex

Li, M., Yuan, J., Yuan, H., Wu, B.-H., Huang, S., Li, Q., Ou, T., Wang, H., Tan, J., Li, D., et al. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c00467 · Cited by 23 · see citing works

Conformational Plasticity of Parallel G-Quadruplex─Implications on Duplex-Quadruplex Motifs.

Sannapureddi, R. K. R., Mohanty, M. K., Salmon, L., & Sathyamoorthy, B. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c03218 · Cited by 16 · see citing works

G-quadruplex-driven molecular disassembly and type I-to-type II photophysical conversion of a heavy-atom-free photosensitizer for site-specific oxidative damage

Saczuk, K., Cottini, M. V., Dudek, M., Mazur, L. M., Sánchez, D. P., López‐Pacios, L., Kassem, A., Matczyszyn, K., Nogueira, J. J., Monnereau, C., et al. (2025) · Nanoscale Horizons · doi:10.1039/d5nh00237k · Cited by 22 · see citing works

Ligand-observed NMR techniques to probe RNA-small molecule interactions

Calabrese, D. R., Connelly, C. M., & Schneekloth, J. S. (2019) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2019.05.030 · Cited by 22 · see citing works

Distinguishing G-Quadruplexes Stabilizer and Chaperone for c-MYC Promoter G-Quadruplexes through Single-Molecule Manipulation.

Zhang, Y.-S., Cheng, Y., Luo, Q., Wu, T.-B., Huo, J.-F., Yin, M., Peng, H., Xiao, Y., Tong, Q.-Y., & You, H. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.3c09074 · Cited by 17 · see citing works

Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems

Boer, R. E., Torrey, Z. R., & Schneekloth, J. S. (2020) · ACS Chemical Biology · doi:10.1021/acschembio.0c00001 · Cited by 21 · see citing works

Targeting MYC: Multidimensional regulation and therapeutic strategies in oncology

Duan, Y., Liu, Z., Wang, Q., Zhang, J., Liu, J., Zhang, Z., & Li, C. (2024) · Genes & Diseases · doi:10.1016/j.gendis.2024.101435 · Cited by 21 · see citing works

MYC inhibitors in multiple myeloma

Martínez-Martín, S., & Soucek, L. (2021) · Cancer Drug Resistance · doi:10.20517/cdr.2021.55 · Cited by 20 · see citing works

Bisindolylmaleimide Ligands Stabilize c-MYC G-Quadruplex DNA Structure and Downregulate Gene Expression

Kumar, S., Sannapureddi, R. K. R., Todankar, C. S., Ramanathan, R., Biswas, A., Sathyamoorthy, B., & Pradeepkumar, P. I. (2022) · Biochemistry · doi:10.1021/acs.biochem.2c00116 · Cited by 19 · see citing works

Selective stabilization of multiple promoter G-quadruplex DNA by using 2-phenyl-1H-imidazole-based tanshinone IIA derivatives and their potential suppressing function in the metastatic breast cancer

Zeng, L., Wu, Q., Wang, T., Li, L., Zhao, X., Chen, K., Qian, J., Li, Y., Xu, H., & Mei, W. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.104433 · Cited by 19 · see citing works

c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells

Pawłowska, M., Kulesza, J., & Augustin, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063061 · Cited by 18 · see citing works

Molecular Recognition of the Hybrid-Type G-Quadruplexes in Human Telomeres

Wu, G., Chen, L., Liu, W., & Yang, D. (2019) · Molecules · doi:10.3390/molecules24081578 · Cited by 17 · see citing works

Guanine anchoring: a strategy for specific targeting of a G-quadruplex using short PNA, LNA and DNA molecules

Tan, D. J. Y., Das, P., Winnerdy, F. R., Lim, K. W., & Phan, A. T. (2020) · Chemical Communications · doi:10.1039/d0cc01778g · Cited by 17 · see citing works

Selective Recognition of a Single HIV-1 G-Quadruplex by Ultrafast Small-Molecule Screening

Scalabrin, M., Nadai, M., Tassinari, M., Lago, S., Doria, F., Frasson, I., Freccero, M., & Richter, S. N. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.0c04106 · Cited by 16 · see citing works

Repurposing FDA-approved drugs to target G-quadruplexes in breast cancer.

Moraca, F., Arciuolo, V., Marzano, S., Napolitano, F., Castellano, G., D'Aria, F., Porzio, A. D., Landolfi, L., Catalanotti, B., Randazzo, A., et al. (2025) · European journal of medicinal chemistry · doi:10.1016/j.ejmech.2025.117245 · Cited by 14 · see citing works

Solution structures and effects of a platinum compound successively bound MYC G-quadruplex

Liu, W.-T., Zhu, B., Liu, L.-Y., Xia, X., Jang, J., Dickerhoff, J., Yang, D.-Z., & Mao, Z.-W. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae649 · Cited by 11 · see citing works

Loop-mediated fluorescent probes for selective discrimination of parallel and antiparallel G-Quadruplexes

Pandith, A., Nagarajachari, U., Kumara, G. S. R., Lee, S., Park, C., Krishnaveni, S., & Seo, Y. J. (2021) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2021.116077 · Cited by 15 · see citing works

Design, synthesis, and biological evaluation of novel benzimidazolyl isoxazole derivatives as potential c-Myc G4 stabilizers to suppress c-Myc transcription and myeloma growth

Geng, X., Zhang, Y., Li, S.-H., Liu, L., Yao, R., Liu, L., & Gao, J. (2022) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2022.134673 · Cited by 14 · see citing works

Discovery of an Orally Efficacious MYC Inhibitor for Liver Cancer Using a GNMT-Based High-Throughput Screening System and Structure–Activity Relationship Analysis

Kant, R., Yang, M., Tseng, C.-H., Yen, C., Li, W.-Y., Tyan, Y., Chen, M., Tzeng, C., Chen, W.-C., You, K., et al. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c00093 · Cited by 13 · see citing works

To probe the binding of TMPyP4 to c-MYC G-quadruplex with in water and in imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations

Paradis, N. J., Clark, A. K., Gogoj, H., Lakernick, P. M., Vaden, T. D., & Wu, C. F. (2022) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2022.120097 · Cited by 13 · see citing works

Structural recognition of the MYC promoter G-quadruplex by a quinoline derivative: insights into molecular targeting of parallel G-quadruplexes

Dickerhoff, J., Dai, J., & Yang, D. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab330 · Cited by 86 · see citing works

Human MYC G-quadruplex: From discovery to a cancer therapeutic target

Wang, W., Hu, S., Gu, Y., Yan, Y., Stovall, D. B., Li, D., & Sui, G. (2020) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2020.188410 · Cited by 76 · see citing works

Abstract 3840: High-resolution structural insights into targeting the MYC oncogene G-quadruplex with the quinoline derivative PEQ

Dickerhoff, J., Dai, J., & Yang, D. (2023) · Cancer Research · doi:10.1158/1538-7445.am2023-3840

Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics

Chaudhuri, R., Bhattacharya, S., Dash, J., & Bhattacharya, S. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c01145 · Cited by 127 · see citing works

Transcriptional regulation of MYC through G-quadruplex structures

Balaratnam, S., & Schneekloth, J. S. (2020) · Annual reports in medicinal chemistry · doi:10.1016/bs.armc.2020.05.002 · Cited by 12 · see citing works