A national cohort study (2000–2018) of long-term air pollution exposure and incident dementia in older adults in the United States

Shi, Liuhua; Steenland, Kyle; Li, Haomin; Liu, Pengfei; Zhang, Yuhan; Lyles, Robert H.; Requia, Weeberb J.; Ilango, Sindana D.; Chang, Howard H.; Wingo, Thomas; Weber, Rodney J.; Schwartz, Joel

doi:10.1038/s41467-021-27049-2

A national cohort study (2000–2018) of long-term air pollution exposure and incident dementia in older adults in the United States

Air pollution may increase risk of Alzheimer’s disease and related dementias (ADRD) in the U.S., but the extent of this relationship is unclear. Here, we constructed two national U.S. population-based cohorts of those aged ≥65 from the Medicare Chronic Conditions Warehouse (2000–2018), combined w…