The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
Hydrogel tapes for fault-tolerant strong wet adhesion
Open accessAbstract
Fast and strong bio-adhesives are in high demand for many biomedical applications, including closing wounds in surgeries, fixing implantable devices, and haemostasis. However, most strong bio-adhesives rely on the instant formation of irreversible covalent crosslinks to provide strong surface binding. Repositioning misplaced adhesives during surgical operations may cause severe secondary damage to tissues. Here, we report hydrogel tapes that can form strong physical interactions with tissues in seconds and gradually form covalent bonds in hours. This timescale-dependent adhesion mechanism allows instant and robust wet adhesion to be combined with fault-tolerant convenient surgical operations. Specifically, inspired by the catechol chemistry discovered in mussel foot proteins, we develop an electrical oxidation approach to controllably oxidize catechol to catecholquinone, which reacts slowly with amino groups on the tissue surface. We demonstrate that the tapes show fast and reversible adhesion at the initial stage and ultrastrong adhesion after the formation of covalent linkages over hours for various tissues and electronic devices. Given that the hydrogel tapes are biocompatible, easy to use, and robust for bio-adhesion, we anticipate that they may find broad biomedical and clinical applications.
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Cites
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Tough adhesives for diverse wet surfaces
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Dry double-sided tape for adhesion of wet tissues and devices
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Cited by
Ren, H., Zhang, Z., Cheng, X., Zou, Z., Chen, X., & He, C. (2023) · Science Advances · doi:10.1126/sciadv.adh4327 · Cited by 431
Liang, Y., Xu, H., Li, Z., Zhangji, A., & Guo, B. (2022) · Nano-Micro Letters · doi:10.1007/s40820-022-00928-z · Cited by 313
Engineering Smart Composite Hydrogels for Wearable Disease Monitoring
Li, J., Ding, Q., Wang, H., Wu, Z., Gui, X., Li, C., Hu, N., Tao, K., & Wu, J. (2023) · Nano-Micro Letters · doi:10.1007/s40820-023-01079-5 · Cited by 304
A natural biological adhesive from snail mucus for wound repair
Deng, T., Gao, D., Song, X., Zhou, Z., Zhou, L., Tao, M., Jiang, Z., Yang, L., Luo, L., Zhou, A., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-35907-4 · Cited by 289
Bioinspired polydopamine hydrogels: Strategies and applications
Xu, Y., Hu, J., Hu, J., Cheng, Y., Chen, X., Gu, Z., & Li, Y. (2023) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2023.101740 · Cited by 285
Metadata
- Authors
- Xue, B., Gu, J., Li, L., Yu, W., Yin, S., Qin, M., Jiang, Q., Wang, W., & Cao, Y.
- Venue
- Nature Communications
- Published
- 2021-12-09
- Volume
- 12
- Issue
- 1
- Pages
- 7156-7156
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W4206321479
- Cited by
- 319
- References
- 67
- FWCI
- 39.19
- Type
- journal article
- Language
- en
- Open access
- gold
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- Xue, B., Gu, J., Li, L., Yu, W., Yin, S., Qin, M., Jiang, Q., Wang, W., & Cao, Y. (2021). Hydrogel tapes for fault-tolerant strong wet adhesion. Nature Communications. https://doi.org/10.1038/s41467-021-27529-5
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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