Cited by 210Molecular Sensors and Ion DetectionNanoplatforms for cancer theranosticsLuminescence and Fluorescent Materials

Successively activatable ultrasensitive probe for imaging tumour acidity and hypoxia

Zheng, Xianchuang, Mao, Hui, Huo, Da, Wu, Wei, Liu, Baorui, Jiang, Xiqun·2017·Nature Biomedical Engineering

Integrity signals

Registry

Crossref · 10.1038/s41551-017-0057

Cites

42 of 42 references verified0 citation errors · 0 not checkable

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  • Proof of concept for synthetic biomarkers has been shown in mice by sequential activation through tumour acidity and hypoxia, enabling imaging of tumours as small as 1 mm.

    “sequential activation by tumour acidity and hypoxia for ultrasensitive imaging detection of tumours as small as 1 mm in mice,90”

    From Early detection of pancreatic cancer (2020) · cites this paper as [90]

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Authors
Zheng, X., Mao, H., Huo, D., Wu, W., Liu, B., & Jiang, X.
Affiliations
  • Nanjing University (CN)
  • Emory University (US)
  • Nanjing Drum Tower Hospital (CN)
Corresponding author
Jiang, Xiqun
Venue
Nature Biomedical Engineering
Published
2017-04-10
Volume
1
Issue
4
ISSN
2157-846X (ISSN-L)
OpenAlex
W2606689723
Cited by
210
References
42
Citations by year
2026: 6 · 2025: 14 · 2024: 16 · 2023: 24 · 2022: 33 · 2021: 30 · 2020: 39 · 2019: 24 · 2018: 16 · 2017: 8
FWCI
11.76
Type
journal article
Language
en
Open access
closed
Locations
Nature Biomedical Engineering (publishedVersion)
Topics
  • Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
Keywords
tumor acidosis, tumor hypoxia, near-infrared imaging, iridium(III) complexes, polyethylene glycol conjugates, signal propagation, molecular imaging probes

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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