The DOI matches its Crossref record; 46 of the 47 references it cites were found in a registry or an index.
RETRACTED ARTICLE: Machine learning of neural representations of suicide and emotion concepts identifies suicidal youth
Open accessAbstract
The clinical assessment of suicidal risk would be significantly complemented by a biologically-based measure that assesses alterations in the neural representations of concepts related to death and life in people who engage in suicidal ideation. This study used machine-learning algorithms (Gaussian Naïve Bayes) to identify such individuals (17 suicidal ideators vs 17 controls) with high (91%) accuracy, based on their altered fMRI neural signatures of death and life-related concepts. The most discriminating concepts were death, cruelty, trouble, carefree, good, and praise. A similar classification accurately (94%) discriminated 9 suicidal ideators who had made a suicide attempt from 8 who had not. Moreover, a major facet of the concept alterations was the evoked emotion, whose neural signature served as an alternative basis for accurate (85%) group classification. The study establishes a biological, neurocognitive basis for altered concept representations in participants with suicidal ideation, which enables highly accurate group membership classification.
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“An emerging line of research points to altered neural activation (Just et al. 2017, Miller et al. 2018, Pan et al. 2013, Quevedo et al. 2016) and neural network connectivity (Chase et al. 2017; Ordaz et al. 2018; Zhang et al. 2014, 2016) in PFC regions among individuals with a history of suicidal ideation or behavior.”
From Adolescent Suicide as a Failure of Acute Stress-Response Systems. (2019) · cites this paper as Just et al. 2017
In the citing paper
“A similar classification approach also discriminates suicide ideators and attempters.”
From Neural correlates associated with suicide and nonsuicidal self-injury in youth (2021) · cites this paper as [86]
In the citing paper
“Findings show distinct neural signatures in the left inferior parietal region and left IFG that are predictive of suicide ideator group membership (86).”
From Neural correlates associated with suicide and nonsuicidal self-injury in youth (2021) · cites this paper as [86]
In the citing paper
“fMRI-measured neural representation of mental concept representations differentiates suicidal ideators from suicide attempters and healthy control subjects (273).”
From A brain-centric model of suicidal behavior (2020) · cites this paper as [273]
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Citations
Cites
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Predicting Human Brain Activity Associated with the Meanings of Nouns
Mitchell, T. M., Shinkareva, S. V., Carlson, A., Chang, K.-M., Malave, V. L., Mason, R. A., & Just, M. A. (2008) · Science · doi:10.1126/science.1152876 · Cited by 1,180
Advances in cognitive theory and therapy: The generic cognitive model
Beck, A. T., & Haigh, E. A. P. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153734 · Cited by 1,055
Research works printed but not linked: 1
- Beck, A. T., Schuyler, D. & Herman, I. in The Prediction of Suicide (eds Beck, A. T. et al.) 45–56 (Charles Press, Bowie, MD, 1974).
Cited by
Sorted by citations
High-performance medicine: the convergence of human and artificial intelligence
Topol, E. J. (2019) · Nature Medicine · doi:10.1038/s41591-018-0300-7 · Cited by 10,450
The integrated motivational–volitional model of suicidal behaviour
O'Connor, R. C., & Kirtley, O. J. (2018) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2017.0268 · Cited by 1,781
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Schmaal, L., van Harmelen, A.-L., Chatzi, V., Lippard, E. T. C., Toenders, Y. J., Averill, L. A., Mazure, C. M., & Blumberg, H. P. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0587-x · Cited by 373
Suicidal Ideation Detection: A Review of Machine Learning Methods and Applications
Ji, S., Pan, S., Li, X., Cambria, E., Long, G., & Huang, Z. H. (2020) · IEEE Transactions on Computational Social Systems · doi:10.1109/tcss.2020.3021467 · Cited by 275
Adolescent Suicide as a Failure of Acute Stress-Response Systems.
Miller, A. B., & Prinstein, M. J. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095625 · Cited by 235
“An emerging line of research points to altered neural activation (Just et al. 2017, Miller et al. 2018, Pan et al. 2013, Quevedo et al. 2016) and neural network connectivity (Chase et al. 2017; Ordaz et al. 2018; Zhang et al. 2014, 2016) in PFC regions among individuals with a history of suicidal…”
Background
Metadata
- Authors
- Just, M. A., Pan, L., Cherkassky, V. L., McMakin, D. L., Cha, C., Nock, M. K., & Brent, D.
- Affiliations
- Carnegie Mellon University (US)
- University of Pittsburgh (US)
- Florida International University (US)
- Columbia University (US)
- Harvard University (US)
- Corresponding author
- Just, Marcel Adam
- Venue
- Nature Human Behaviour
- Published
- 2017-10-30
- Volume
- 1
- Issue
- 12
- Pages
- 911-919
- ISSN
- 2397-3374 (ISSN-L)
- PMC
- PMC5777614
- OpenAlex
- W2766099988
- Cited by
- 210
- References
- 47
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 11 · 2023: 20 · 2022: 28 · 2021: 48 · 2020: 29 · 2019: 35 · 2018: 24 · 2017: 4
- FWCI
- 30.89
- Type
- journal article
- Language
- en
- Status
- Retracted
- Update notices
- retraction (2023-04-06)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Nature Human Behaviour (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
- ORBi (University of Liège) (submittedVersion, other-oa)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- University of Pittsburgh
- National Institute of Mental Health (MH029617, R01MH029617, R01MH116652)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Social Psychology › Mental Health via Writing
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- suicidal ideation, suicide risk assessment, youth suicide, emotional processing, suicide attempts, retracted article
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