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Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING
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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Ishikawa, H., & Barber, G. N. (2008) · Nature · doi:10.1038/nature07317 · Cited by 3,576
Type I interferons in infectious disease
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LocusZoom: regional visualization of genome-wide association scan results
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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D. R., Latz, E., & Fitzgerald, K. A. (2009) · Nature · doi:10.1038/nature07725 · Cited by 2,627
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J., & Alnemri, E. S. (2009) · Nature · doi:10.1038/nature07710 · Cited by 1,831
cGAS–STING drives ageing-related inflammation and neurodegeneration
Gulen, M. F., Samson, N., Keller, A., Schwabenland, M., Liu, C., Glück, S., Thacker, V. V., Favre, L., Mangeat, B., Kroese, L. J., et al. (2023) · Nature · doi:10.1038/s41586-023-06373-1 · Cited by 1,104 · cited 1×
“Due to the potential for pleiotropic effects of a full knockout cell line, we treated WT macrophages with increasing concentrations of the STING inhibitor H-151 39,40 .”
An integrated model of the recognition of Candida albicans by the innate immune system
Netea, M. G., Brown, G. D., Kullberg, B. J., & Gow, N. A. R. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1815 · Cited by 946
Tight nuclear tethering of cGAS is essential for preventing autoreactivity
Volkman, H. E., Cambier, S., Gray, E. E., & Stetson, D. B. (2019) · eLife · doi:10.7554/elife.47491 · Cited by 303
Candida albicans biofilm–induced vesicles confer drug resistance through matrix biogenesis
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Metadata
- Authors
- Brown Harding, H., Kwaku, G. N., Reardon, C. M., Khan, N. S., Zamith-Miranda, D., Zarnowski, R., Tam, J. M., Bohaen, C. K., Richey, L., Mosallanejad, K., Crossen, A. J., Reedy, J. L., Ward, R. A., Vargas-Blanco, D. A., Basham, K. J., Bhattacharyya, R. P., Nett, J. E., Mansour, M. K., van de Veerdonk, F. L., Kumar, V., Kagan, J. C., Andes, D. R., Nosanchuk, J. D., & Vyas, J. M.
- Venue
- Nature Microbiology
- Published
- 2024-01-02
- Volume
- 9
- Issue
- 1
- Pages
- 95-107
- ISSN
- 2058-5276
- Cited by
- 82
- References
- 15
- Language
- en
- Licence
- Funders
- U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (R01AI150181, 1K08AI14755, R01AI153405, R21AI159583, R01AI167993, R01AI073289, R21AI156104, RO1AI132638)
- Fund for Medical Discovery (FMD) at Massachusetts General Hospital
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