The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Nanoplastics are neither microplastics nor engineered nanoparticles
Open accessAbstract
Increasing concern and research on the subject of plastic pollution has engaged the community of scientists working on the environmental health and safety of nanomaterials. While many of the methods developed in nano environment, health and safety work have general applicability to the study of particulate plastics, the nanometric size range has important consequences for both the analytical challenges of studying nanoscale plastics and the environmental implications of these incidental nanomaterials. Related to their size, nanoplastics are distinguished from microplastics with respect to their transport properties, interactions with light and natural colloids, a high fraction of particle molecules on the surface, bioavailability and diffusion times for the release of plastic additives. Moreover, they are distinguished from engineered nanomaterials because of their high particle heterogeneity and their potential for rapid further fragmentation in the environment. These characteristics impact environmental fate, potential effects on biota and human health, sampling and analysis. Like microplastics, incidentally produced nanoplastics exhibit a diversity of compositions and morphologies and a heterogeneity that is typically absent from engineered nanomaterials. Therefore, nanoscale plastics must be considered as distinct from both microplastics and engineered nanomaterials.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The possible formation of heteroaggregates between nanoplastics or other natural organic matter has long been recognized as a potential challenge in the analysis of nanoplastics and may influence toxicological outcomes within a biological exposure (11).”
From Rapid single-particle chemical imaging of nanoplastics by SRS microscopy (2024) · cites this paper as [11]
Citations
Cites
Production, use, and fate of all plastics ever made
Geyer, R., Jambeck, J. R., & Law, K. L. (2017) · Science Advances · doi:10.1126/sciadv.1700782 · Cited by 18,606
Plastic waste inputs from land into the ocean
Jambeck, J. R., Geyer, R., Wilcox, C., Siegler, T. R., Perryman, M., Andrady, A., Narayan, R., & Law, K. L. (2015) · Science · doi:10.1126/science.1260352 · Cited by 13,163
Eriksen, M., Lebreton, L. C. M., Carson, H. S., Thiel, M., Moore, C. J., Borerro, J. C., Galgani, F., Ryan, P. G., & Reisser, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111913 · Cited by 4,710
Horton, A. A., Walton, A., Spurgeon, D. J., Lahive, E., & Svendsen, C. (2017) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.01.190 · Cited by 3,756
Life in the “plastisphere”: microbial communities on plastic marine debris
Zettler, E. R., Mincer, T. J., & Amaral-Zettler, L. A. (2013) · Environmental Science & Technology · doi:10.1021/es401288x · Cited by 3,368
Hartmann, N. B., Hüffer, T., Thompson, R. C., Hassellöv, M., Verschoor, A., Daugaard, A. E., Rist, S., Karlsson, T., Brennholt, N., Cole, M., et al. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.8b05297 · Cited by 2,881
Nanoparticle-mediated cellular response is size-dependent
Jiang, W., Kim, B. Y. S., Rutka, J. T., & Chan, W. C. W. (2008) · Nature Nanotechnology · doi:10.1038/nnano.2008.30 · Cited by 2,814
Alimi, O. S., Farner Budarz, J., Hernandez, L. M., & Tufenkji, N. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.7b05559 · Cited by 2,668
Self-citationMourdikoudis, S., Pallares, R. M., & Thanh, N. T. K. (2018) · Nanoscale · doi:10.1039/c8nr02278j · Cited by 2,328
Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective
Auffan, M., Rose, J., Bottero, J., Lowry, G. V., Jolivet, J., & Wiesner, M. R. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.242 · Cited by 2,026
Self-citationCurrent opinion: What is a nanoplastic?
Gigault, J., Halle, A. T., Baudrimont, M., Pascal, P.-Y., Gauffre, F., Phi, T.-L., El Hadri, H., Grassl, B., & Reynaud, S. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.01.024 · Cited by 2,010
Self-citationNanoparticle Silver Released into Water from Commercially Available Sock Fabrics
Benn, T. M., & Westerhoff, P. K. (2008) · Environmental Science & Technology · doi:10.1021/es7032718 · Cited by 1,713
A global inventory of small floating plastic debris
van Sebille, E., Wilcox, C., Lebreton, L., Maximenko, N., Hardesty, B. D., van Franeker, J. A., Eriksen, M., Siegel, D., Galgani, F., & Law, K. L. (2015) · Environmental Research Letters · doi:10.1088/1748-9326/10/12/124006 · Cited by 1,713
Amaral-Zettler, L. A., Zettler, E. R., & Mincer, T. J. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0308-0 · Cited by 1,407
Rethinking microplastics as a diverse contaminant suite
Rochman, C. M., Brookson, C., Bikker, J., Djuric, N., Earn, A., Bucci, K., Athey, S., Huntington, A., McIlwraith, H., Munno, K., et al. (2019) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4371 · Cited by 1,258
Petosa, A. R., Jaisi, D. P., Quevedo, I. R., Elimelech, M., & Tufenkji, N. (2010) · Environmental Science & Technology · doi:10.1021/es100598h · Cited by 1,175
Self-citationPlastic Teabags Release Billions of Microparticles and Nanoparticles into Tea
Hernandez, L. M., Xu, E. G., Larsson, H. C. E., Tahara, R., Maisuria, V. B., & Tufenkji, N. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b02540 · Cited by 1,165
Self-citationAFM-IR: Technology and Applications in Nanoscale Infrared Spectroscopy and Chemical Imaging
Dazzi, A., & Prater, C. B. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00448 · Cited by 1,087
Turning microplastics into nanoplastics through digestive fragmentation by Antarctic krill
Dawson, A. L., Kawaguchi, S., King, C. K., Townsend, K. A., King, R., Huston, W. M., & Bengtson Nash, S. M. (2018) · Nature Communications · doi:10.1038/s41467-018-03465-9 · Cited by 1,023
Size-dependent toxicity of metal oxide particles—A comparison between nano- and micrometer size
Karlsson, H. L., Gustafsson, J., Cronholm, P., & Möller, L. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.03.014 · Cited by 949
Nanoplastic in the North Atlantic subtropical gyre
Ter Halle, A., Jeanneau, L., Martignac, M., Jardé, E., Pedrono, B., Brach, L., & Gigault, J. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b03667 · Cited by 897
Self-citationSchwab, F., Zhai, G., Kern, M., Turner, A. A., Schnoor, J. L., & Wiesner, M. R. (2015) · Nanotoxicology · doi:10.3109/17435390.2015.1048326 · Cited by 888
Self-citationOrganic micropollutants in marine plastics debris from the open ocean and remote and urban beaches
Hirai, H., Takada, H., Ogata, Y., Yamashita, R., Mizukawa, K., Saha, M., Kwan, C. S., Moore, C. J., Gray, H. E., Laursen, D., et al. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.06.004 · Cited by 862
Liu, P., Zhan, X., Wu, X., Li, J., Wang, H., & Gao, S. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2019.125193 · Cited by 817
Separation and Analysis of Microplastics and Nanoplastics in Complex Environmental Samples
Nguyen, B., Claveau-Mallet, D., Hernandez, L. M., Xu, E. G., Farner, J. M., & Tufenkji, N. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.8b00602 · Cited by 763
Self-citationDomingos, R. F., Baalousha, M., Ju‐Nam, Y., Reid, M., Tufenkji, N., Lead, J. R., Leppard, G. G., & Wilkinson, K. J. (2009) · Environmental Science & Technology · doi:10.1021/es900249m · Cited by 596
Self-citationRist, S., Baun, A., & Hartmann, N. B. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.05.048 · Cited by 571
Interactions between trace metals and plastic production pellets under estuarine conditions
Holmes, L., Turner, A., & Thompson, R. (2014) · Marine Chemistry · doi:10.1016/j.marchem.2014.06.001 · Cited by 566
Benchmarking the in Vitro Toxicity and Chemical Composition of Plastic Consumer Products
Zimmermann, L., Dierkes, G., Ternes, T. A., Völker, C., & Wagner, M. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b02293 · Cited by 438
Formation of microscopic particles during the degradation of different polymers
Lambert, S., & Wagner, M. (2016) · Chemosphere · doi:10.1016/j.chemosphere.2016.07.042 · Cited by 436
Stone, V., Nowack, B., Baun, A., van den Brink, N. W., von der Kammer, F., Dušinská, M., Handy, R. D., Hankin, S. M., Hassellöv, M., Joner, E. J., et al. (2009) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2009.10.035 · Cited by 415
Entry of nanoparticles into cells: the importance of nanoparticle properties
Zhao, J., & Stenzel, M. H. (2017) · Polymer Chemistry · doi:10.1039/c7py01603d · Cited by 398
Al-Sid-Cheikh, M., Rowland, S. J., Stevenson, K., Rouleau, C., Henry, T. B., & Thompson, R. C. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.8b05266 · Cited by 397
Azimi, P., Zhao, D., Pouzet, C., Crain, N., & Stephens, B. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.5b04983 · Cited by 388
Mitrano, D. M., Beltzung, A., Frehland, S., Schmiedgruber, M., Cingolani, A., & Schmidt, F. (2019) · Nature Nanotechnology · doi:10.1038/s41565-018-0360-3 · Cited by 351
Mintenig, S. M., Bäuerlein, P. S., Koelmans, A. A., Dekker, S. C., & van Wezel, A. P. (2018) · Environmental Science Nano · doi:10.1039/c8en00186c · Cited by 348
Exposure to endocrine disrupting compounds via the food chain: Is packaging a relevant source?
Muncke, J. (2009) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2009.05.006 · Cited by 313
Nanoplastics formed during the mechanical breakdown of daily-use polystyrene products
Ekvall, M. T., Lundqvist, M., Kelpsiene, E., Šileikis, E., Gunnarsson, S. B., & Cedervall, T. (2019) · Nanoscale Advances · doi:10.1039/c8na00210j · Cited by 304
Baalousha, M., Stolpe, B., & Lead, J. R. (2011) · Journal of Chromatography A · doi:10.1016/j.chroma.2011.04.063 · Cited by 297
Things we know and don’t know about nanoplastic in the environment
Wagner, S., & Reemtsma, T. (2019) · Nature Nanotechnology · doi:10.1038/s41565-019-0424-z · Cited by 275
von der Kammer, F., Legros, S., Hofmann, T., Larsen, E. H., & Loeschner, K. (2011) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2010.11.012 · Cited by 270
Are nanoplastics able to bind significant amount of metals? The lead example
Davranche, M., Veclin, C., Pierson‐Wickmann, A., Hadri, H. E., Grassl, B., Rowenczyk, L., Dia, A., ter Halle, A., Blancho, F., Reynaud, S., et al. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.03.087 · Cited by 209
Self-citationWang, Y., Westerhoff, P. K., & Hristovski, K. D. (2011) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2011.10.086 · Cited by 200
Correia, M., & Loeschner, K. (2018) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-018-0919-8 · Cited by 190
Miao, L., Hou, J., You, G., Liu, Z., Liu, S., Li, T., Mo, Y., Guo, S., & Qu, H. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.113300 · Cited by 181
Quantitative Analysis of Fullerene Nanomaterials in Environmental Systems: A Critical Review
Isaacson, C. W., Kleber, M., & Field, J. A. (2009) · Environmental Science & Technology · doi:10.1021/es900692e · Cited by 173
Gangadoo, S., Owen, S., Rajapaksha, P., Plaisted, K., Cheeseman, S., Haddara, H., Truong, V. K., Ngô, S. T., Vu, V. V., Cozzolino, D., et al. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138792 · Cited by 152
Ruenraroengsak, P., Novák, P., Berhanu, D., Thorley, A. J., Valsami‐Jones, E., Gorelik, J., Korchev, Y. E., & Tetley, T. D. (2011) · Nanotoxicology · doi:10.3109/17435390.2011.558643 · Cited by 136
Pulmonary Effects Induced by Ultrafine PTFE Particles
Johnston, C. J., Finkelstein, J. N., Wade-Mercer, P., Corson, N., Gelein, R. M., & Oberdörster, G. (2000) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2000.9037 · Cited by 131
Gigault, J., Hadri, H. E., Reynaud, S., Deniau, E., & Grassl, B. (2017) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-017-0629-7 · Cited by 128
Self-citationBolea, E., Lamana, J. J., Laborda, F., & Castillo, J. R. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-011-5201-2 · Cited by 110
Quantification of C60 fullerene concentrations in water
Chen, Z., Westerhoff, P. K., & Herckès, P. (2008) · Environmental Toxicology and Chemistry · doi:10.1897/07-560.1 · Cited by 109
Balakrishnan, G., Déniel, M., Nicolaï, T., Chassenieux, C., & Lagarde, F. (2018) · Environmental Science Nano · doi:10.1039/c8en01005f · Cited by 106
Koelmans, A. A. (2019) · Nature Nanotechnology · doi:10.1038/s41565-019-0416-z · Cited by 76
Assessing the environmental transformation of nanoplastic through 13C-labelled polymers
Sander, M., Kohler, H. E., & McNeill, K. (2019) · Nature Nanotechnology · doi:10.1038/s41565-019-0420-3 · Cited by 73
Soap- and metal-free polystyrene latex particles as a nanoplastic model
Pessoni, L., Veclin, C., Hadri, H. E., Cugnet, C., Davranche, M., Pierson‐Wickmann, A., Gigault, J., Grassl, B., & Reynaud, S. (2019) · Environmental Science Nano · doi:10.1039/c9en00384c · Cited by 64
Self-citationHow Should Engineered Nanomaterials Be Regulated for Public and Environmental Health?
Resnik, D. B. (2019) · The AMA Journal of Ethic · doi:10.1001/amajethics.2019.363 · Cited by 28
Mercea, P., Kalisch, A., Ulrich, M., Benz, H., Piringer, O., Toşa, V., Schuster, R., Aranyi, S., & Sejersen, P. (2017) · Polymer Testing · doi:10.1016/j.polymertesting.2017.11.025 · Cited by 27
Astefanei, A., Kok, W. T., Bäuerlein, P. S., Núñez, Ó., Galceran, M. T., de Voogt, P., & Schoenmakers, P. J. (2015) · Journal of Chromatography A · doi:10.1016/j.chroma.2015.07.004 · Cited by 11
Modelling migration of substances from polymers into drinking water
Mercea, P., Kalisch, A., Schuster, R., & Ulrich, M. (2017) · OpenUMWELT · doi:10.60810/openumwelt-779 · Cited by 2
Research works printed but not linked: 2
- Rist, S. & Hartmann, N. B. in Freshwater Microplastics: Emerging Environmental Contaminants? (eds Wagner, M. & Lambert, S.) 25–49 (Springer, 2018).
- Crank J. The Mathematics of Diffusion (Elsevier, 1975).
Cited by
Sorted by citations
Chemical Analysis of Microplastics and Nanoplastics: Challenges, Advanced Methods, and Perspectives
Ivleva, N. P. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00178 · Cited by 1,172
Risk assessment of microplastic particles
Koelmans, A. A., Redondo‐Hasselerharm, P. E., Nor, N. H. M., de Ruijter, V. N., Mintenig, S. M., & Kooi, M. (2022) · Nature Reviews Materials · doi:10.1038/s41578-021-00411-y · Cited by 1,204
Microplastics and nanoplastics in the marine-atmosphere environment
Allen, D., Allen, S., Abbasi, S., Baker, A. R., Bergmann, M., Brahney, J., Butler, T. M., Duce, R. A., Eckhardt, S., Evangeliou, N., et al. (2022) · Nature Reviews Earth & Environment · doi:10.1038/s43017-022-00292-x · Cited by 501
The Minderoo-Monaco Commission on Plastics and Human Health
Landrigan, P. J., Raps, H., Cropper, M., Bald, C., Brunner, M., Canonizado, E. M., Charles, D., Chiles, T. C., Donohue, M. J., Enck, J., et al. (2023) · Annals of Global Health · doi:10.5334/aogh.4056 · Cited by 581
Occurrence of Polyethylene Terephthalate and Polycarbonate Microplastics in Infant and Adult Feces
Zhang, J., Wang, L., Trasande, L., & Kannan, K. (2021) · Environmental Science & Technology Letters · doi:10.1021/acs.estlett.1c00559 · Cited by 487
Metadata
- Authors
- Gigault, J., El Hadri, H., Nguyen, B., Grassl, B., Rowenczyk, L., Tufenkji, N., Feng, S., & Wiesner, M.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- McGill University (CA)
- Duke University (US)
- Venue
- Nature Nanotechnology
- Published
- 2021-04-29
- Volume
- 16
- Issue
- 5
- Pages
- 501-507
- ISSN
- 1748-3387 (ISSN-L)
- 1748-3395
- OpenAlex
- W3157443957
- Cited by
- 954
- References
- 60
- Citations by year
- 2026: 178 · 2025: 222 · 2024: 207 · 2023: 163 · 2022: 136 · 2021: 48
- FWCI
- 6.73
- Type
- journal article
- Language
- en
- Open access
- green
- univ-pau.hal.science
- Licence
- Locations
- Nature Nanotechnology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- eScholarship@McGill (McGill) (submittedVersion)
- Topics
- Physical Sciences › Environmental Science › Pollution › Microplastics and Plastic Pollution
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Physical Sciences › Materials Science › Materials Chemistry › Nanoparticles: synthesis and applications
- Keywords
- nanoplastics, microplastics, engineered nanoparticles, plastic pollution, environmental fate, particle size effects, fragmentation, polymer additives, bioavailability, environmental health and safety
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review