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Cited by 1,362

The DOI matches its Crossref record; 331 of the 331 references it cites were found in a registry or an index.

Multimorbidity

Open access
Skou, Søren T., Mair, Frances S., Fortin, Martin, Guthrie, Bruce, Nunes, Bruno P., Miranda, J. Jaime, Boyd, Cynthia M., Pati, Sanghamitra, Mtenga, Sally, Smith, Susan M.·2022·Nature Reviews Disease Primers
DOI 10.1038/s41572-022-00376-4
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Abstract

Multimorbidity (two or more coexisting conditions in an individual) is a growing global challenge with substantial effects on individuals, carers and society. Multimorbidity occurs a decade earlier in socioeconomically deprived communities and is associated with premature death, poorer function and quality of life and increased health-care utilization. Mechanisms underlying the development of multimorbidity are complex, interrelated and multilevel, but are related to ageing and underlying biological mechanisms and broader determinants of health such as socioeconomic deprivation. Little is known about prevention of multimorbidity, but focusing on psychosocial and behavioural factors, particularly population level interventions and structural changes, is likely to be beneficial. Most clinical practice guidelines and health-care training and delivery focus on single diseases, leading to care that is sometimes inadequate and potentially harmful. Multimorbidity requires person-centred care, prioritizing what matters most to the individual and the individual’s carers, ensuring care that is effectively coordinated and minimally disruptive, and aligns with the patient’s values. Interventions are likely to be complex and multifaceted. Although an increasing number of studies have examined multimorbidity interventions, there is still limited evidence to support any approach. Greater investment in multimorbidity research and training along with reconfiguration of health care supporting the management of multimorbidity is urgently needed. Multimorbidity (two or more coexisting conditions in an individual) has substantial effects on individuals, carers and society. This Primer by Skou and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of multimorbidity. Moreover, this Primer summarizes the effect of multimorbidity on quality of life and discusses open research questions for this condition.

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Metadata

Authors
Skou, S. T., Mair, F. S., Fortin, M., Guthrie, B., Nunes, B. P., Miranda, J. J., Boyd, C. M., Pati, S., Mtenga, S., & Smith, S. M.
Venue
Nature Reviews Disease Primers
Publisher
Springer Science and Business Media LLC
Published
2022-07-14
Volume
8
Issue
1
Pages
48-48
ISSN
2056-676X (ISSN-L)
DOI
10.1038/s41572-022-00376-4
OpenAlex
W4285390610
Cited by
1,362
References
331
FWCI
55.17
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Multimorbidity. https://app.cochat.ai/papers/10.1038/s41572-022-00376-4
The paper
Skou, S. T., Mair, F. S., Fortin, M., Guthrie, B., Nunes, B. P., Miranda, J. J., Boyd, C. M., Pati, S., Mtenga, S., & Smith, S. M. (2022). Multimorbidity. Nature Reviews Disease Primers. https://doi.org/10.1038/s41572-022-00376-4

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.