The gut microbiota–brain axis in behaviour and brain disorders

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The Microbiota-Gut-Brain Axis

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The role of the gut microbiota in shaping the tumor microenvironment and immunotherapy of breast cancer

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The gut-brain axis in the context of colorectal cancer

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Psychoactive Effects of Lactobacillus johnsonii BS15 on Preventing Memory Dysfunction Induced by Acute Ethanol Exposure Through Modulating Intestinal Microenvironment and Improving Alcohol Metabolic Level

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Neuron-periphery mitochondrial stress communication in aging and diseases

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Different feeding patterns affect meat quality of Tibetan pigs associated with intestinal microbiota alterations

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Altered gut microbiota in patients with idiopathic Parkinson’s disease: an age–sex matched case–control study

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Corinthian Currants Supplementation Restores Serum Polar Phenolic Compounds, Reduces IL-1beta, and Exerts Beneficial Effects on Gut Microbiota in the Streptozotocin-Induced Type-1 Diabetic Rat

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Review of the Health Benefits of Cereals and Pseudocereals on Human Gut Microbiota

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Acetobacter pasteurianus BP2201 alleviates alcohol‐induced hepatic and neuro‐toxicity and modulate gut microbiota in mice

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Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions

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Isolation and Purification of Bacterial Extracellular Vesicles from Human Feces Using Density Gradient Centrifugation

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Causal Link between Gut Microbiota, Neurophysiological States, and Bone Diseases: A Comprehensive Mendelian Randomization Study

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Composition of gut microbiota and its correlations with neurological, intestinal, cardiovascular and metabolic diseases

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Nutritional strategies modulating the gut microbiome as a preventative and therapeutic approach in normal and pathological age-related cognitive decline: a systematic review of preclinical and clinical findings

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Combined repetitive transcranial magnetic stimulation and gut microbiota modulation through the gut–brain axis for prevention and treatment of autism spectrum disorder

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Brain plasticity and ginseng

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Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota

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Ambient long-term exposure to organophosphorus pesticides and the human gut microbiome: an observational study

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Rhodiola rosea: a review in the context of PPPM approach

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Using Synbiotics as a Therapy to Protect Mental Health in Alzheimer's Disease

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Gut-to-brain neuromodulation by synthetic butyrate-producing commensal bacteria

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Exploring the hypothetical links between environmental pollutants, diet, and the gut-testis axis: The potential role of microbes in male reproductive health

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The Quest for Eternal Youth: Hallmarks of Aging and Rejuvenating Therapeutic Strategies

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Chemical genetic approaches to dissect microbiota mechanisms in health and disease

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The microbiota-gut-brain axis: a potential target in the small-molecule compounds and gene therapeutic strategies for Parkinson’s disease

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Comparative genomics and metabolite analysis of Lactiplantibacillus plantarum strains in dairy and vegetable fermentation environments

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Gut–Brain Axis and Brain Microbiome Interactions from a Medical Perspective

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Decoding the impact of gut microbiota on heart failure

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Maternal Microbiota Transfer Programs Offspring Eating Behavior

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An integrative study of the microbiome gut-brain-axis and hippocampal inflammation in psychosis: Persistent effects from mode of birth

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The Increased Abundance of Commensal Microbes Decreases Drosophila melanogaster Lifespan through an Age-Related Intestinal Barrier Dysfunction

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Obesity Reshapes the Microbial Population Structure along the Gut-Liver-Lung Axis in Mice

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Modulatory Effects of Huoxiang Zhengqi Oral Liquid on Gut Microbiome Homeostasis Based on Healthy Adults and Antibiotic-Induced Gut Microbial Dysbiosis Mice Model

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Antibiotic Treatment during Pregnancy Alters Offspring Gut Microbiota in a Sex-Dependent Manner

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Placebo-resistant gut bacteria: Akkermansia muciniphila spp. and Familial Mediterranean fever disease

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Adolescent Aggression: A Narrative Review on the Potential Impact of Violent Video Games

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Dietary modulation of pubertal timing: gut microbiota-derived SCFAs and neurotransmitters orchestrate hypothalamic maturation via the gut–brain axis

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Interaction Between Konjac Glucomannan and Gut Microbiota and Its Impact on Health

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The association between gut microbiota and functional connectivity in cognitive impairment of first-episode major depressive disorder

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Chronic Stress During Pregnancy Causes Impairments in Emotional Behavior to Offspring May Through BDNF/TrkB Signaling Pathway and Gut Microbiota

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High cholesterol diet, oxysterols and their impact on the gut–brain axis

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Gastrointestinal organoids in the study of viral infections

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Urbanization associates with restricted gut microbiome diversity and delayed maturation in infants

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The fecal microbiota from children with autism impact gut metabolism and learning and memory abilities of honeybees

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Gut microbiota and metabolites in estrus cycle and their changes in a menopausal transition rat model with typical neuroendocrine aging

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The Causal Relationships Between Gut Microbiota, Brain Volume, and Intelligence: A Two-Step Mendelian Randomization Analysis

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Engineered microorganisms: A new direction in kidney stone prevention and treatment

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Gut microbiota profile in CDKL5 deficiency disorder patients

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Application of Microbiome-Based Therapies in Chronic Respiratory Diseases

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Environmental concentrations of microplastic-induced gut microbiota and metabolite disruption in silkworm, Bombyx mori

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The Gut-Brain Axis in Alzheimer’s and Parkinson’s Diseases: The Catalytic Role of Mitochondria

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Hosts manipulate lifestyle switch and pathogenicity heterogeneity of opportunistic pathogens in the single-cell resolution

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A strong priority effect in the assembly of a specialized insect-microbe symbiosis

Chen, J. Z., Junker, A., Zheng, I., Gerardo, N. M., & Vega, N. M. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.00818-24 · Cited by 13

Strain-resolved de-novo metagenomic assembly of viral genomes and microbial 16S rRNAs

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In a rodent model of autism, probiotics decrease gut leakiness in relation to gene expression of GABA receptors: Emphasize how crucial the gut–brain axis

Bin-Khattaf, R. M., Al-Dbass, A. M., Alonazi, M. A., Bhat, R. S., Al-Daihan, S., & El-Ansary, A. K. (2024) · Translational Neuroscience · doi:10.1515/tnsci-2022-0354 · Cited by 14

Association between small intestine bacterial overgrowth and psychiatric disorders

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Multiple pathways through which the gut microbiota regulates neuronal mitochondria constitute another possible direction for depression

Zhao, H., Qiu, X., Wang, S., Wang, Y., Xie, L., Xia, X., & Li, W. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1578155 · Cited by 14

Recurring Gastrointestinal Infections Increase the Risk of Dementia

Fink, A., Doblhammer, G., & Tamgüney, G. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210316 · Cited by 13

Bacillus subtilis plays a role in the inhibition of transporter ABCB1 in Caco-2 cells

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Skeletal muscle insulin resistance and adipose tissue hypertrophy persist beyond the reshaping of gut microbiota in young rats fed a fructose-rich diet

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Disruption of the lung-gut-brain axis is responsible for cortex damage induced by pulmonary exposure to zinc oxide nanoparticles

Zhang, L., Zhang, Y., Jiang, X., Mao, L., Xia, Y., Fan, Y., Li, N., Jiang, Z., Qin, X., Jiang, Y., et al. (2022) · Toxicology · doi:10.1016/j.tox.2022.153390 · Cited by 13

Dual-parameter cell biosensor for real-time monitoring of effects of propionic acid on neurons

Ju, Y., Li, H., Li, J., Gu, N., & Yang, F. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115227 · Cited by 13

Responses of the intestinal microbiota to exposure of okadaic acid in marine medaka Oryzias melastigma

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Study on the comorbid mechanisms of sarcopenia and late-life depression

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Gut Microbiota in Patients with Type 1 Narcolepsy.

Zhang, R., Gao, S., Wang, S., Zhang, J., Bai, Y., He, S., Zhao, P., & Zhang, H. (2021) · PubMed Central · doi:10.2147/nss.s330022 · Cited by 12

Bacterial Communications and Computing in Internet of Everything (IoE)

Koca, B. Y., & Akan, Ö. B. (2024) · IEEE Communications Surveys & Tutorials · doi:10.1109/comst.2024.3451302 · Cited by 14

Effects of Lacticaseibacillus paracasei K56 on perceived stress among pregraduate students: a double-blind, randomized, placebo-controlled trial

Guan, Y., Zhu, R., Zhao, W., Wang, L., You, L., Zeng, Z., Jiang, Q., Zhu, Z., Gou, J., Zhang, Q., et al. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1544713 · Cited by 17

Acetamiprid mediates cognitive dysfunction through the gut-brain axis: Synaptic damage and immune-mediated blood-brain barrier dysfunction

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Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis

Ren, P., Zhao, Y., Li, X., Xie, J., Liao, X.-X., Luo, Q., Liu, X., Li, J., Fan, Y., Cheng, X., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1599570 · Cited by 12

Restoring Balance: The Role of Omega-3 Polyunsaturated Fatty Acids on the Gut–Brain Axis and Other Interconnected Biological Pathways to Improve Depression

Cillis, F. D., Begni, V., Genini, P., Leo, D., Riva, M. A., & Cattaneo, A. (2025) · Nutrients · doi:10.3390/nu17213426 · Cited by 15

The Pediatric Microbiota–Gut–Brain Axis: Implications for Neuropsychiatric Development and Intervention

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The effects of polyphenols on gut microbial metabolites and composition in neurodegenerative diseases: a systematic review

Zafari, R., Goudarzi, N., Kamroo, A., Tafti, M. F., Ghorbani, A., Talebian, N., Najafi, S., Shahbazian, S., Rahmanian, M., Parvardeh, S., et al. (2025) · Nutrition & Metabolism · doi:10.1186/s12986-025-01022-y · Cited by 14

Berberine in Bowel Health: Anti-Inflammatory and Gut Microbiota Modulatory Effects

Duda-Madej, A., Viscardi, S., Łabaz, J. P., Topola, E., Szewczyk, W., & Gagat, P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262412021 · Cited by 13

The gut microbiota influences neurodegenerative diseases through the gut-brain axis: molecular mechanisms and effects on immune function

Yang, J., Song, X., Yan, S., Li, Q., & Yang, W. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1739329 · Cited by 13

Resolving cognitive heterogeneity in white matter hyperintensities through integrated analyses of microbiome, metabolome, and brain glymphatic function

Xu, X., Zhou, X., Zhang, M., Fang, J., Yan, Z., Zhu, X., Yu, Y., & Zhu, J. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71201 · Cited by 12

Gut Microbes Regulate Innate Immunity and Epilepsy

Zhang, L., Li, S., Tai, Z., Yu, C., & Xu, Z. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.870197 · Cited by 11

Atp11b Deletion Affects the Gut Microbiota and Accelerates Brain Aging in Mice

Liu, C., Zhang, S., Shi, H., Zhou, H., Zhuang, J., Cao, Y., Ward, N., & Wang, J. (2022) · Brain Sciences · doi:10.3390/brainsci12060709 · Cited by 13

Unresolved Systemic Inflammation, Long COVID, and the Common Pathomechanisms of Somatic and Psychiatric Comorbidity

Liang, C., Gałecki, P., & Su, K. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11175114 · Cited by 13

The Serotonergic System and Amyotrophic Lateral Sclerosis: A Review of Current Evidence

Lu, Y., Cheng, Y., Zhu, Y., Cui, L., & Li, X. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01320-0 · Cited by 12

Early gut microbiological changes and metabolomic changes in patients with sepsis: a preliminary study

Zhou, Y., Luo, Y., Wang, X., Luan, F., Peng, Y., Li, Y., Ma, X., Jia, X., Li, N., Man, M., et al. (2023) · International Microbiology · doi:10.1007/s10123-023-00363-z · Cited by 13

Abnormalities in Clostridioides and related metabolites before ACTH treatment may be associated with its efficacy in patients with infantile epileptic spasm syndrome

Wan, L., Shi, X., Yan, H., Liang, Y., Liu, X., Zhu, G., Zhang, J., Wang, J., Wang, M., & Yang, G. (2023) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14398 · Cited by 11

Metaorganismal choline metabolism shapes olfactory perception

Massey, W. J., Kay, K. E., Jaramillo, T. C., Horak, A. J., Cao, S., Osborn, L. J., Banerjee, R., Mrdjen, M., Hamoudi, M. K., Silver, D. J., et al. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105299 · Cited by 13

Methodological recommendations for human microbiota-gut-brain axis research

Ou, Y., Belzer, C., Smidt, H., & de Weerth, C. (2023) · Microbiome Research Reports · doi:10.20517/mrr.2023.33 · Cited by 14

Review of Phytochemical Potency as a Natural Anti-Helicobacter pylori and Neuroprotective Agent

Tandoro, Y., Chen, B.-K., Ali, A., & Wang, C. (2023) · Molecules · doi:10.3390/molecules28207150 · Cited by 15

Interaction between Per- and Polyfluorinated Substances (PFAS) and Acetaminophen in Disease Exacerbation—Focusing on Autism and the Gut–Liver–Brain Axis

Jiang, D. Q. Y., & Guo, T. L. (2024) · Toxics · doi:10.3390/toxics12010039 · Cited by 13

The Role of Gut Microbiota in Neuromyelitis Optica Spectrum Disorder

Yao, S., Yang, X., Cen, L., & Tan, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25063179 · Cited by 12

Feeding Drosophila gut microbiomes from young and old flies modifies the microbiome

Wesseltoft, J. B., Danielsen, C. D., Andersen, A. M., de Jonge, N., Olsen, A., Rohde, P. D., & Kristensen, T. N. (2024) · Scientific Reports · doi:10.1038/s41598-024-58500-1 · Cited by 10

Evolution and the critical role of the microbiota in the reduced mental and physical health associated with low socioeconomic status (SES)

Rook, G. A. W. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105653 · Cited by 12

Common gastrointestinal symptoms and their impact on psychological state and quality of life in patients with inflammatory bowel disease: a cross-sectional multicenter study in China

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The role of the gut microbiome in neuroinflammation and chemotherapy-induced peripheral neuropathy

Shatunova, S., Aktar, R., Peiris, M., Lee, J. Y. P., Vetter, I., & Starobova, H. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176818 · Cited by 15

Maternal gut Bifidobacterium breve modifies fetal brain metabolism in germ-free mice

López‐Tello, J., Kiu, R., Schofield, Z., Zhang, C. X. W., van Sinderen, D., Gall, G. L., Hall, L. J., & Sferruzzi-Perri, A. N. (2024) · Molecular Metabolism · doi:10.1016/j.molmet.2024.102004 · Cited by 14

Cross-talk between adipose tissue and microbiota-gut-brain-axis in brain development and neurological disorder

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Two-Year Study on the Intra-Individual Dynamics of Gut Microbiota and Short-Chain Fatty Acids Profiles in Healthy Adults

Senina, A. M., Markelova, M., Khusnutdinova, D. R., Siniagina, M., Kupriyanova, O. V., Synbulatova, G. E., Kayumov, A. R., Boulygina, E. A., & Grigoryeva, T. V. (2024) · Microorganisms · doi:10.3390/microorganisms12081712 · Cited by 13

Gut microbiota and its metabolites: A potential approach for traditional Chinese medicine-derived non-starch polysaccharides to delay aging and prevent age-related diseases–A review

Zhang, Q., Liu, Y., Tang, R., Kong, S., Lv, D., Li, H., Yang, H., & Lin, L. (2024) · Carbohydrate Polymer Technologies and Applications · doi:10.1016/j.carpta.2024.100567 · Cited by 12

Spatiotemporal dynamics of the developing zebrafish enteric nervous system at the whole-organ level

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Microbes in Health and Disease: Human Gut Microbiota

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The function of gut microbiota in immune-related neurological disorders: a review

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Host–microbe interactions: communication in the microbiota–gut–brain axis

Shekarabi, A., Qureishy, I., Puglisi, C. H., Dalseth, M., & Vuong, H. E. (2024) · Current Opinion in Microbiology · doi:10.1016/j.mib.2024.102494 · Cited by 36

The gut microbiota–brain axis in neurological disorders

You, M., Chen, N., Yang, Y., Cheng, L., He, H., Cai, Y., Liu, Y., Liu, H., & Hong, G. (2024) · MedComm · doi:10.1002/mco2.656 · Cited by 113

Microbiome and Diseases: Gut–Brain Axis and Neurological Disorders

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Gut Microbes: The Gut Brain Connection

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