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The evolution of SARS-CoV-2
Open accessAbstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths and substantial morbidity worldwide. Intense scientific effort to understand the biology of SARS-CoV-2 has resulted in daunting numbers of genomic sequences. We witnessed evolutionary events that could mostly be inferred indirectly before, such as the emergence of variants with distinct phenotypes, for example transmissibility, severity and immune evasion. This Review explores the mechanisms that generate genetic variation in SARS-CoV-2, underlying the within-host and population-level processes that underpin these events. We examine the selective forces that likely drove the evolution of higher transmissibility and, in some cases, higher severity during the first year of the pandemic and the role of antigenic evolution during the second and third years, together with the implications of immune escape and reinfections, and the increasing evidence for and potential relevance of recombination. In order to understand how major lineages, such as variants of concern (VOCs), are generated, we contrast the evidence for the chronic infection model underlying the emergence of VOCs with the possibility of an animal reservoir playing a role in SARS-CoV-2 evolution, and conclude that the former is more likely. We evaluate uncertainties and outline scenarios for the possible future evolutionary trajectories of SARS-CoV-2.
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“The higher end of the ranges, with evolutionary rates up to 8 × 10 -3 substitutions per site per year, emphasises the potential for SARS-CoV-1 and similar coronaviruses to evolve rapidly, possibly even quicker than SARS-CoV-2.126”
From Severe acute respiratory syndrome (SARS) mathematical models and disease parameters: a systematic review (2025) · cites this paper as [126]
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Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N.-H., Nitsche, A., et al. (2020) · Cell · doi:10.1016/j.cell.2020.02.052 · Cited by 20,286
EVOLUTION IN MENDELIAN POPULATIONS
Wright, S. (1931) · Genetics · doi:10.1093/genetics/16.2.97 · Cited by 9,237
Virological assessment of hospitalized patients with COVID-2019
Wölfel, R., Corman, V. M., Guggemos, W., Seilmaier, M., Zange, S., Müller, M. A., Niemeyer, D., Jones, T. C., Vollmar, P., Rothe, C., et al. (2020) · Nature · doi:10.1038/s41586-020-2196-x · Cited by 6,661
Origin and evolution of pathogenic coronaviruses
Cui, J., Li, F., & Shi, Z. (2018) · Nature Reviews Microbiology · doi:10.1038/s41579-018-0118-9 · Cited by 5,729
Korber, B., Fischer, W. M., Gnanakaran, S., Yoon, H., Theiler, J., Abfalterer, W., Hengartner, N., Giorgi, E. E., Bhattacharya, T., Foley, B., et al. (2020) · Cell · doi:10.1016/j.cell.2020.06.043 · Cited by 4,281
Coronaviruses: An Overview of Their Replication and Pathogenesis
Fehr, A. R., & Perlman, S. M. (2015) · Methods in molecular biology · doi:10.1007/978-1-4939-2438-7_1 · Cited by 3,910
Structural basis of receptor recognition by SARS-CoV-2
Shang, J., Ye, G., Shi, K., Wan, Y., Luo, C., Aihara, H., Geng, Q., Auerbach, A., & Li, F. (2020) · Nature · doi:10.1038/s41586-020-2179-y · Cited by 3,661
SARS-CoV-2 variants, spike mutations and immune escape
Harvey, W. T., Carabelli, A. M., Jackson, B., Gupta, R. K., Thomson, E. C., Harrison, E. M., Ludden, C., Reeve, R., Rambaut, A., COVID-19 Genomics UK (COG-UK) Consortium, et al. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-021-00573-0 · Cited by 3,528
Nextstrain: real-time tracking of pathogen evolutionPreprint
Hadfield, J., Megill, C., Bell, S. M., et al. (2017) · bioRxiv · doi:10.1101/224048 · Cited by 3,172
Nextstrain: real-time tracking of pathogen evolution
Hadfield, J., Megill, C., Bell, S. M., Huddleston, J., Potter, B., Callender, C., Sagulenko, P., Bedford, T., & Neher, R. A. (2018) · Bioinformatics · doi:10.1093/bioinformatics/bty407 · Cited by 3,154
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Alves, K., Kouassi, A., Nelson, J., Plested, J. S., Kalkeri, R., Zhu, M., Cloney-Clark, S., Cai, Z., Ahmed, A., McKnight, I., et al. (2025) · Vaccine · doi:10.1016/j.vaccine.2025.128164 · Cited by 5
Lambisia, A. W., Nyiro, J. U., Githinji, G., Katama, E. N., Moraa, E., Morobe, J. M., Mutunga, M. N., Maina, G., Bejon, P., Phan, M. V. T., et al. (2026) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofag084 · Cited by 5
Chung, C. W., Irudayaraj, P., Lallow, E. O., Xu, Z., Park, Y. K., Kudchodkar, S. B., Montaner, L. J., Srinivasan, A., & Muthumani, K. (2024) · Frontiers in Virology · doi:10.3389/fviro.2024.1399993 · Cited by 5
Saldaña, F., Stollenwerk, N., & Aguiar, M. (2024) · Royal Society Open Science · doi:10.1098/rsos.240919 · Cited by 3
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Piesche, R., Breithaupt, A., Pohlmann, A., Ahrens, A. K., Beer, M., Harder, T., & Grund, C. (2024) · npj Viruses · doi:10.1038/s44298-024-00062-0 · Cited by 4
Self-citationLi, Y., Zhang, X., Tai, W., Zhuang, X., Shi, H., Liao, S., Yu, X., Mei, R., Chen, X., Huang, Y., et al. (2024) · EBioMedicine · doi:10.1016/j.ebiom.2024.105437 · Cited by 4
Refining SARS-CoV-2 intra-host variation by leveraging large-scale sequencing data
Mostefai, F., Grenier, J., Poujol, R., & Hussin, J. (2024) · NAR Genomics and Bioinformatics · doi:10.1093/nargab/lqae145 · Cited by 4
Clouston, S., Vaska, P., Babalola, T. K., Gardus, J. D., Huang, C., Soriolo, N., Fontana, A., DeLorenzo, C., Parsey, R. V., & Luft, B. J. (2025) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2025.100945 · Cited by 5
Pediatric COVID-19 severity by SARS-CoV-2 lineage and vaccine status in Canada: an IMPACT study
Farrar, D. S., Bettinger, J. A., Campigotto, A. J., Deeks, S. L., Drouin, O., Embree, J. E., Haddad, É., Halperin, S. A., Jadavji, T., Kazmi, K., et al. (2025) · Pediatric Research · doi:10.1038/s41390-025-03853-0 · Cited by 4
Dai, Y.-C., Lin, Y.-C., Ching, L. L., Tsai, J., Ishikawa, K. M., Tsai, W.-Y., Chen, J. J., Nerurkar, V. R., & Wang, W. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.04081-22 · Cited by 4
SARS-CoV-2: An Update on the Biological Interplay with the Human Host
Lippi, G., Sanchis‐Gomar, F., Mattiuzzi, C., & Henry, B. M. (2023) · COVID · doi:10.3390/covid3100108 · Cited by 4
Stercel, V., Lóczi, L., Kadenczki, O., Nemes, É., Nagy, B., Hodossy-Takács, R., Szabó, A. Á., Fagyas, M., Kappelmayer, J., Szabó, T. G., et al. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1257072 · Cited by 4
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Rodríguez‐Artalejo, F., Ruiz‐Galiana, J., Cantón, R., Ramos, P. D. L., Botella, A. G., García‐Lledó, A., Hernández‐Sampelayo, T., Gómez‐Pavón, J., del Castillo, J. M. G., Martín-Delgado, M. C., et al. (2023) · Revista Española de Quimioterapia · doi:10.37201/req/123.2023 · Cited by 4
Weber, A., Översti, S., & Kühnert, D. (2023) · Virus Evolution · doi:10.1093/ve/vead070 · Cited by 4
On the space of SARS-CoV-2 genetic sequence variants
Palyanov, A. Y., & Palyanova, N. V. (2023) · Vavilov Journal of Genetics and Breeding · doi:10.18699/vjgb-23-97 · Cited by 4
Perevaryukha, A. Y. (2023) · Technical Physics · doi:10.1134/s1063784223060038 · Cited by 4
Викторович, К. С., Guselnikov, S. V., Nekrasov, B. G., Molodykh, S. V., Kuvshinova, I. N., Murasheva, S. V., Николаевна, Б. Т., Gorchakov, A. A., Chikaev, A. N., Chikaev, N. A., et al. (2024) · Vaccines · doi:10.3390/vaccines12010055 · Cited by 4
Bivalent Omicron BA.4/BA.5 BNT162b2 Vaccine in 6-Month- to <12-Year-Olds
Sher, L., Boakye-Appiah, J. K., Hill, S., Wasserman, E. J., Xu, X., Maldonado, Y., Walter, E. B., Muñoz, F. M., Paulsen, G. C., Englund, J. A., et al. (2024) · Journal of the Pediatric Infectious Diseases Society · doi:10.1093/jpids/piae062 · Cited by 4
Hong, B., Li, M., & Fan, H. (2024) · MedComm · doi:10.1002/mco2.578 · Cited by 4
FeverNet: Enabling accurate and robust remote fever screening
Yan, M., Qian, J., Shao, H., Luo, L., & Yang, J. (2024) · Pattern Recognition · doi:10.1016/j.patcog.2024.110755 · Cited by 4
Daigle, L., Khalid, H., Gagnon, C. A., Arsenault, J., Bienzle, D., Bisson, S.-K., Blais, M., Denis-Robichaud, J., Forest, C., St-Sauveur, V. G., et al. (2024) · BMC Veterinary Research · doi:10.1186/s12917-024-04150-4 · Cited by 4
SARS-CoV-2 infectivity and antigenic evasion: spotlight on isolated Omicron sub-lineages
Barrera, A., Martínez-Valdebenito, C., Angulo, J., Palma, C., Hormazábal, J., Vial, C., Aguilera, X., Castillo-Torres, P. N., Pardo‐Roa, C., Balcells, M. E., et al. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2024.1414331 · Cited by 4
Li, J., Yang, J., Ding, X. L., Zhou, H., Han, N., & Wu, A. (2024) · Virologica Sinica · doi:10.1016/j.virs.2024.09.003 · Cited by 4
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Wang, Q., Wang, Y., Li, J., Liu, H. S., & Chen, S. (2024) · Exploration of Drug Science · doi:10.37349/eds.2024.00071 · Cited by 4
Jones, C. H., Beitelshees, M., Williams, B. A., Hill, A. B., Welch, V., & True, J. M. (2024) · PNAS Nexus · doi:10.1093/pnasnexus/pgae558 · Cited by 3
Laro, J. A., Xue, B., Zheng, J. H., Ness, M., Perlman, S. M., & McCall, L. (2025) · iScience · doi:10.1016/j.isci.2024.111727 · Cited by 4
Jia, K. M., Boyer, C., Wallinga, J., & Lipsitch, M. (2025) · Epidemiology · doi:10.1097/ede.0000000000001839 · Cited by 7
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Emery, I. F., & Rosen, C. J. (2025) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2025.02.007 · Cited by 4
Patel, M., Shamim, U., Umang, U., Pandey, R., & Narayan, J. (2025) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0012918 · Cited by 4
Qiao, R., Liu, Y., Mao, Q., Li, J., Lu, Y., Shi, J., Li, C., Yu, J., Gong, J., Wang, X., et al. (2025) · MedComm · doi:10.1002/mco2.70191 · Cited by 4
Jimenez-Araya, B., Gourgeon, A., N’Debi, M., Thompson, T., Démontant, V., Simitambe, A., Lau, M., Boizeau, L., Bruscella, P., Cappy, P., et al. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.02092-24 · Cited by 4
James‐Pemberton, P. H., Kohli, S., Twynham, J., Westlake, A. C., Antill, A., Hunt, J., Olkhov, R., & Shaw, A. M. (2025) · Immunology · doi:10.1111/imm.70083 · Cited by 5
Bashor, L., Gallichotte, E. N., Galvan, M., Erbeck, K., Croft, L., Stache, K., Stenglein, M. D., Johnson, J. G., Pabilonia, K. L., & VandeWoude, S. (2025) · Nature Communications · doi:10.1038/s41467-025-66402-7 · Cited by 4
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Ose, N. J., Campitelli, P., Modi, T., Kazan, I. C., Kumar, S., & Ozkan, S. B. (2023) · eLife · doi:10.7554/elife.92063 · Cited by 9
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Zumbrun, E. E., Zak, S. E., Lee, E. D., Bowling, P. A., Ruiz, S. I., Zeng, X., Koehler, J. W., Delp, K. L., Bakken, R. R., Hentschel, S., et al. (2023) · Viruses · doi:10.3390/v15122341 · Cited by 4
Presence of neutralizing SARS‐CoV‐2 antibodies in asymptomatic population of N'Djamena, Chad
Wondeu, A. L. D., Abakar, M. F., Frasca, F., Nodjikouambaye, Z. A., Zakaria, F. A., Naïbeï, N., Dzomo, G. R. T., Djimtoïbaye, D., Mad-Toïngué, J., Scagnolari, C., et al. (2024) · Immunity Inflammation and Disease · doi:10.1002/iid3.1154 · Cited by 3
Negi, S. S., Sharma, K. K., Bhargava, A., & Singh, P. (2024) · Archives of Microbiology · doi:10.1007/s00203-023-03807-2 · Cited by 4
RNA barcode segments for SARS-CoV-2 identification from HCoVs and SARSr-CoV-2 lineages
You, C., Jiang, S., Ding, Y., Ye, S., Zou, X., Zhang, H., Li, Z., Chen, F., Li, Y., Ge, X., et al. (2024) · Virologica Sinica · doi:10.1016/j.virs.2024.01.006 · Cited by 4
Bykonia, E. N., Kleymenov, D. A., Gushchin, V. А., Siniavin, A. E., Mazunina, E. P., Kuznetsova, N. A., Kozlova, S. R., Zolotar, A. N., Shidlovskaya, E. V., Usachev, E. V., et al. (2024) · Vaccines · doi:10.3390/vaccines12040379 · Cited by 4
Lee, K., Na, Y., Kim, M., Lee, D., Choi, J., Kim, G., & Kim, M.-S. (2024) · Pharmacology Research & Perspectives · doi:10.1002/prp2.1194 · Cited by 3
Lytton, S. D., Ghosh, A. K., Bulbul, M. R. H., Nafisa, T., Mamunur, R., Meier, C., Landt, O., & Kaiser, M. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e31011 · Cited by 4
Su, H.-H., Lin, E., Huang, Y., Lien, Y., & Huang, C.-Y. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25116120 · Cited by 4
Thomas, A. R., Battenfeld, T., Kraiselburd, I., Anastasiou, O. E., Dittmer, U., Dörr, A.-K., Dörr, A., Elsner, C., Gosch, J., Le‐Trilling, V. T. K., et al. (2024) · BMC Genomics · doi:10.1186/s12864-024-10539-0 · Cited by 4
Dings, C., Selzer, D., Bragazzi, N. L., Möhler, E., Wenning, M., Gehrke, T., Richter, U., Nonnenmacher, A., Brinkmann, F., Rothoeft, T., et al. (2024) · Infectious Disease Modelling · doi:10.1016/j.idm.2024.07.004 · Cited by 4
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Russell, S. L., Penunuri, G., & Condon, C. (2024) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2024.07.001 · Cited by 3
Sivertsen, A., Mortensen, N., Solem, U., Valen, E., Bullita, M. F., Wensaas, K., Litleskare, S., Rørtveit, G., Grewal, H. M. S., & Ulvestad, E. (2024) · mSphere · doi:10.1128/msphere.00114-24 · Cited by 4
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Pereira, A., Amaral, L., Dias, I., Magalhães, A., Abreu, V., Esteves, M., Vilarinho, R., & Cervaens, M. (2024) · Cardiopulmonary Physical Therapy Journal · doi:10.1097/cpt.0000000000000272 · Cited by 5
Lee, J. S., Dittmar, M., Miller, J., Li, M., Ayyanathan, K., Ferretti, M., Hulahan, J., Whig, K., Etwebi, Z., Griesman, T., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.13.566859 · Cited by 4
Jones, A. D. G. (2024) · doi:10.1002/9781119742975.ch21 · Cited by 4
Addetia, A., Schäfer, A., Sprouse, K. R., Valdez, A., Taylor, A., Navarro, M.-J., Brown, J. T., Leaf, E. M., Miranda, M. C., Walls, A. C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.11.652904 · Cited by 4
Ly, T. K., Tachibana, K., Yamamoto, N., Ando, K., Isoda, T., & Kihara, T. (2024) · Human Cell · doi:10.1007/s13577-024-01142-2 · Cited by 3
mRNA vaccines with RBD mutations have broad-spectrum activity against SARS-CoV-2 variants in mice
Liang, X., Yuan, Y., Wang, J., Tang, C., Yang, Y. K., Zhou, Y., Yang, H., Huang, Q., Yu, W., Wang, H., et al. (2025) · npj Vaccines · doi:10.1038/s41541-025-01066-4 · Cited by 3
Schmidt, H., Schick, L., Podlech, J., Renzaho, A., Lieb, B., Diederich, S., Hankeln, T., Plachter, B., & Kriege, O. (2025) · npj Genomic Medicine · doi:10.1038/s41525-025-00463-x · Cited by 3
Hnasko, R. M., Lin, A. V., McGarvey, J. A., & Jackson, E. S. (2025) · Microbial Biotechnology · doi:10.1111/1751-7915.70117 · Cited by 3
Rao, B., Wang, D., Yang, M., Zhao, C., Cheng, M., Li, S., Zhang, D., Luo, H., Qian, G., Wang, L., et al. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-10643-w · Cited by 3
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Baral, B., Saini, V., Singh, S., Verma, T., Rath, D. K., Bahinipati, J., Panda, P., Patro, S., Misra, N., Behera, M. R., et al. (2025) · Journal of Proteome Research · doi:10.1021/acs.jproteome.4c00996 · Cited by 3
Huan, X., Li, M., & Gao, H. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.145340 · Cited by 3
Diya, O., Gayed, J., Lowry, F. S., Ma, H., Bangad, V., Mensa, F., Zou, J., Xie, X., Hu, Y., Cutler, M. W., et al. (2025) · Infectious Diseases and Therapy · doi:10.1007/s40121-025-01185-4 · Cited by 3
Reyes-Ruíz, J. M., Ríos-Ríos, M., & Martínez-Mier, G. (2025) · International Journal of Environmental Health Research · doi:10.1080/09603123.2025.2557428 · Cited by 3
Fialho, M. J., da Silva, C. J. F., Miranda, G. B. A., Assis, I. S. D. S., Moreno, A. M., de Moura, P. H., da Fonseca, A. C. P., Silva, T., & Cardozo, S. V. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1667392 · Cited by 3
Sukik, L., Chemaitelly, H. S., Ayoub, H. H., Coyle, P. V., Tang, P., Hasan, M. R., Yassine, H. M., Thani, A. A. A., Kanaani, Z. A., Al‐Kuwari, E., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-19168-3 · Cited by 3
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Lyu, M. A., Maimaiti, M., Zhong, Z., Hu, J., Zhang, X., Wang, Q., Wang, C., & Hu, H. (2025) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2025.10.012 · Cited by 3
Oh, D., Hölzer, M., Börnigen, D., Paraskevopoulou, S., Duwe, S. C., Budt, M., Kerber, R., Mikołajewska, A., Böttcher, S., Seifried, J., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-01093-1 · Cited by 4
Reguzova, A., Haug, V., Müller, M., Fandrich, M., Dulovic, A., & Amann, R. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1715442 · Cited by 3
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Zhou, X., Guo, L., Li, W., Zeng, P., & Li, J. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.149954 · Cited by 3
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Nie, C., Zoister, C., Ma, G., & Haag, R. (2026) · Accounts of Materials Research · doi:10.1021/accountsmr.5c00285 · Cited by 3
Yurgelonis, I., Rai, D. K., Li, Z., Washington, B., McMonagle, P., Noell, S., Plotnikova, O. V., Nicki, J. A., Craig, T. K., Yang, Q., et al. (2026) · Antiviral Research · doi:10.1016/j.antiviral.2026.106352 · Cited by 3
Ribeiro, F. V. D. S., Valente, R. P. D. P., Kruger, H. G., Araújo, J. D. O., & Silva, J. R. A. (2026) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-026-00763-z · Cited by 3
Mohammadnejad, A., Ma, L., Goldys, E. M., & Deng, F. (2026) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2026.118808 · Cited by 3
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OLIVEIRA, E. A., Oliveira, M. A. S., Júnior, H. M., Oliveira, F. E. S., Martelli, D. R. B., Santos, R. A., MAK, R. H. K., Silva, A. C. S. E., Diniz, L. M. O., Dias, C. D. S., et al. (2026) · Microorganisms · doi:10.3390/microorganisms14040883 · Cited by 3
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Huot, M., Rosenbaum, P., Planchais, C., Mouquet, H., Monasson, R., & Cocco, S. (2026) · Cell Systems · doi:10.1016/j.cels.2026.101673 · Cited by 4
Optimal entropic properties of SARS-CoV-2 RNA sequences
Formentin, M., Chignola, R., & Favretti, M. (2024) · Royal Society Open Science · doi:10.1098/rsos.231369 · Cited by 3
Katte, R. H., Ao, Y., Wang, X., Han, Y., Zhong, G., Ghimire, D., Florence, J., Tucker, T. A., & Lu, M. (2024) · Viruses · doi:10.3390/v16030391 · Cited by 3
Yadav, A. J., Kumar, S., Maurya, S., Bhagat, K., & Padhi, A. K. (2024) · Physical Chemistry Chemical Physics · doi:10.1039/d4cp01014k · Cited by 3
Synergistic peptide combinations designed to suppress SARS-CoV-2
Han, T., Song, L., Niu, X., Qiu, M., Wang, Y., Wang, J., Sun, X., Ma, J., Hu, S., & Feng, Z. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e30489 · Cited by 3
Dynamic expedition of leading mutations in SARS-CoV-2 spike glycoproteins
Hasan, M., He, Z., Jia, M., Leung, A. C. F., Natarajan, K., Xu, W., Yap, S., Zhou, F., Chen, S., Su, H., et al. (2024) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2024.05.037 · Cited by 3
SARS-CoV-2 Variants and COVID-19 in Bangladesh—Lessons Learned
Lytton, S. D., & Ghosh, A. K. (2024) · Viruses · doi:10.3390/v16071077 · Cited by 5
Ullah, I., Symmes, K., Keita, K., Zhu, L., Grunst, M. W., Li, W., Mothes, W., Kumar, P., & Uchil, P. D. (2024) · Vaccines · doi:10.3390/vaccines12091007 · Cited by 3
From Global to Nano: A Geographical Perspective of Aggregatibacter actinomycetemcomitans
Ryder, M. I., Fine, D. H., & Barron, A. E. (2024) · Pathogens · doi:10.3390/pathogens13100837 · Cited by 3
Razzaq, A., Disoma, C., Iqbal, S., Nisar, A., Hameed, M., Qadeer, A., Waqar, M., Mehmood, S. A., Gao, L., Khan, S., et al. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1484637 · Cited by 3
Patiño-Galindo, J. Á., García‐Sastre, A., Kuhn, J. H., Rabadán, R., & Palacios, G. F. (2024) · Journal of Virology · doi:10.1128/jvi.01100-24 · Cited by 3
Sex-Specific HLA Alleles Contribute to the Modulation of COVID-19 Severity
Spartano, S., Faggiano, M. V., Guidi, G., D’Ambrosio, P., Vaisfeld, A., Novelli, A., Falqui, S., Cingolani, A., Lambertenghi, L., Visentin, A., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252313198 · Cited by 3
Rice, A. M., Troendle, E. P., Bridgett, S., Nejad, B. F., McKinley, J. M., National SARS-CoV-2 Surveillance & Whole Genome Sequencing (WGS) Programme, Bradley, D., Fairley, D., Bamford, C., Skvortsov, T., et al. (2024) · Genome Medicine · doi:10.1186/s13073-024-01409-1 · Cited by 3
Bacterial Aerosol Inactivation by DBD Plasma: Mechanisms, Kinetic Model, and Disinfection Dose
Zhang, L., Zhang, X., Zhou, Q., Kaiyue, W., Luo, H., Guo, Y., Tie, J., & Fu, Y. (2025) · IEEE Transactions on Plasma Science · doi:10.1109/tps.2025.3538882 · Cited by 3
PathoSeq-QC: a decision support bioinformatics workflow for robust genomic surveillance
Leoni, G., Petrillo, M., Ruiz‐Serra, V., Querci, M., Coecke, S., & Wiesenthal, T. (2025) · Bioinformatics · doi:10.1093/bioinformatics/btaf102 · Cited by 3
Agudelo, O., Reyes-Loaiza, V., Giraldo-Parra, L., Rosales-Chilama, M., Perdomo, S. A., Gómez, M. A., Rodriguez, J. W., Ortega, V., Rivera, C. F. D., Galindo, D., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-92104-7 · Cited by 3
Berkell, M., Górska, A., Smet, M., Bachelet, D., Gentilotti, E., Guedes, M. N. P., Yusti, A.-M. F., Mazzaferri, F., Lizarazo, E., Matheeussen, V., et al. (2025) · Eurosurveillance · doi:10.2807/1560-7917.es.2025.30.10.2400038 · Cited by 3
Nguyen, B. T., Bertrand, J., Agyeman, A. A., Zhang, S., Yu, L., Harris, V., Little, P. S., Butler, C., Breuer, J., Lowe, D. M., et al. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf158 · Cited by 3
Gutiérrez, M. Á. M., Castiella, I. F., Gros, P. B., Anca, S. G., Fresno, P., Domínguez, J. A. R., Barriocanal, M. B., Lavisier, B. D. M., López, R. L., Sánchez, P. G., et al. (2025) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-025-05100-0 · Cited by 3
SARS-CoV-2 biological clones are genetically heterogeneous and include clade-discordant residues
de Ávila, A. I., Soria, M. E., Martínez‐González, B., Somovilla, P., Mínguez, P., Salar‐Vidal, L., Esteban‐Muñoz, M., Martín-García, M., Zúñiga, S., Sola, I., et al. (2025) · Journal of Virology · doi:10.1128/jvi.02250-24 · Cited by 3
Lyu, L., Veytsel, G. E., Stott, G., Fox, S. J., Dailey, C., Damodaran, L., Fujimoto, K., Brown, P., Sealy, R., Brown, A. O., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00888-6 · Cited by 3
Self-Assembled peptide nanofiber-based nanopharmaceutics for the treatment of viral infections
Demirsoy, Z., Kesici, M. S., Özçubukçu, S., & Gülseren, G. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.164066 · Cited by 3
Perera, D., Li, E., Gordon, P. M. K., van der Meer, F. J. U. M., Lynch, T., Gill, M. J., Church, D. L., de Koning, A. P. J., Huber, C. D., van Marle, G., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60988-8 · Cited by 4
Metadata
- Authors
- Markov, P. V., Ghafari, M., Beer, M., Lythgoe, K., Simmonds, P., Stilianakis, N. I., & Katzourakis, A.
- Affiliations
- University of London (GB)
- University of Oxford (GB)
- Friedrich-Loeffler-Institut (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Corresponding author
- Markov, Peter V.
- Katzourakis, Aris
- ORCID
- Venue
- Nature Reviews Microbiology
- Published
- 2023-04-05
- Volume
- 21
- Issue
- 6
- Pages
- 361-379
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W4362609000
- Semantic Scholar
- b6c3324e790174aac7a7b28fcfe0bc22f5461418
- Cited by
- 1,179
- References
- 225
- Citations by year
- 2026: 204 · 2025: 390 · 2024: 441 · 2023: 130
- FWCI
- 55.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Reviews Microbiology (publishedVersion)
- PubMed (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- OpenAgrar (submittedVersion)
- Funders
- Wellcome Trust (107652/Z/15/Z)
- H2020 European Research Council (101001623)
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
- Keywords
- SARS-CoV-2, viral evolution, genetic variation, variants of concern, antigenic evolution, immune evasion, reinfection, recombination, chronic infection, reservoir hosts, transmissibility, disease severity, COVID-19 pandemic, evolutionary trajectories
- MeSH terms
- COVID-19, SARS-CoV-2, Animals, Genomics, Immune Evasion, Pandemics
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