The DNA damage response to transcription stress

The Hallmarks of Aging

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Repair Pathway Choices and Consequences at the Double-Strand Break

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RNA m6A methylation regulates the ultraviolet-induced DNA damage response

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The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

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Challenges of proving a causal role of somatic mutations in the aging process

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Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development

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Tissue Specificity of DNA Damage and Repair

Hoch, N. C. (2023) · Physiology · doi:10.1152/physiol.00006.2023 · Cited by 18

Epigenetic dynamics of aging and cancer development: current concepts from studies mapping aging and cancer epigenomes

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Transcription-coupled repair of DNA–protein crosslinks

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DNA Polymerase η Promotes the Transcriptional Bypass of N2-Alkyl-2′-deoxyguanosine Adducts in Human Cells

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Impacts of chromatin dynamics and compartmentalization on DNA repair

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LEO1 is a partner for Cockayne syndrome protein B (CSB) in response to transcription-blocking DNA damage

Tiwari, V., Kulikowicz, T., Wilson, D. M., & Bohr, V. A. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab458 · Cited by 18

The molecular basis of human transcription-coupled DNA repair

van der Meer, P. J., & Luijsterburg, M. S. (2025) · Nature Cell Biology · doi:10.1038/s41556-025-01715-9 · Cited by 17

Locked in a vicious cycle: the connection between genomic instability and a loss of protein homeostasis

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In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration

Sant, L. J. V., White, J. J., Hoeijmakers, J. H. J., Vermeij, W. P., & Jaarsma, D. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01200-y · Cited by 17

Beta-Genus Human Papillomavirus 8 E6 Destabilizes the Host Genome by Promoting p300 Degradation

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Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair

Yan, C., Dodd, T., Yu, J., Leung, B., Xu, J., Oh, J., Wang, D., & Ivanov, I. N. (2021) · Nature Communications · doi:10.1038/s41467-021-27295-4 · Cited by 17

DNA Repair in Nucleosomes: Insights from Histone Modifications and Mutants

Selvam, K., Wyrick, J. J., & Parra, M. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25084393 · Cited by 17

From rest to repair: Safeguarding genomic integrity in quiescent cells

Leung, C. W. B., Wall, J., & Esashi, F. (2024) · DNA repair · doi:10.1016/j.dnarep.2024.103752 · Cited by 17

Growth charts in Cockayne syndrome type 1 and type 2

Baer, S., Tuzin, N., Kang, P. B., Mohammed, S. N., Kubota, M., van Ierland, Y., Busa, T., Rossi, M., Morel, G., Michot, C., et al. (2020) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2020.104105 · Cited by 16

A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV

Bay, L. T. E., Syljuåsen, R. G., & Landsverk, H. B. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac434 · Cited by 16

Early‐onset nucleotide excision repair disorders with neurological impairment: Clues for early diagnosis and prognostic counseling

Baer, S., Obringer, C., Julia, S., Chelly, J., Capri, Y., Gras, D., Baujat, G., Félix, T. M., Doray, B., del Pozo, J. S., et al. (2020) · Clinical Genetics · doi:10.1111/cge.13798 · Cited by 16

RNA in DNA repair

Vågbø, C. B., & Slupphaug, G. (2020) · DNA repair · doi:10.1016/j.dnarep.2020.102927 · Cited by 16

Multiple Forms and Functions of Premature Termination by RNA Polymerase II

Bentley, D. L. (2024) · Journal of Molecular Biology · doi:10.1016/j.jmb.2024.168743 · Cited by 15

hnRNPA2B1 deacetylation by SIRT6 restrains local transcription and safeguards genome stability

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RNA polymerase II subunit modulation during viral infection and cellular stress

Gulyas, L., & Glaunsinger, B. A. (2022) · Current Opinion in Virology · doi:10.1016/j.coviro.2022.101259 · Cited by 15

Genome-wide mapping of protein–DNA damage interaction by PADD-seq

Zhu, Y., Tan, Y., Li, L., Xiang, Y., Huang, Y., Zhang, X., Yin, J., Li, J., Lan, F., Qian, M., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad008 · Cited by 15

XPF–ERCC1: Linchpin of DNA crosslink repair

McHugh, P. J. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1008616 · Cited by 15

Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy

Slyšková, J., Muniesa-Vargas, A., da Silva, I. T., Drummond, R. D., Park, J., Häckes, D., Poetsch, I., Ribeiro-Silva, C., Moretton, A., Heffeter, P., et al. (2023) · NAR Cancer · doi:10.1093/narcan/zcad057 · Cited by 14

DNA double-stranded breaks, a hallmark of aging, defined at the nucleotide resolution, are increased and associated with transcription in the cardiac myocytes in LMNA-cardiomyopathy

Cathcart, B., Cheedipudi, S. M., Rouhi, L., Zhao, Z., Gurha, P., & Marian, A. J. (2024) · Cardiovascular Research · doi:10.1093/cvr/cvae063 · Cited by 14

CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division

Costanzo, F., Paccosi, E., Proietti‐De‐Santis, L., & Egly, J. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.06.002 · Cited by 14

Mediator complex in transcription regulation and DNA repair: Relevance for human diseases

Maalouf, C. A., Alberti, A., & Soutourina, J. (2024) · DNA repair · doi:10.1016/j.dnarep.2024.103714 · Cited by 14

C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair

Thijssen, K. L., van der Woude, M., Davó-Martínez, C., Dekkers, D. H. W., Sabatella, M., Demmers, J., Vermeulen, W., & Lans, H. (2021) · Communications Biology · doi:10.1038/s42003-021-02875-8 · Cited by 14

RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma

Tu, Q., Liu, X., Yao, X., Li, R., Liu, G., Jiang, H., Li, K., Chen, Q., Huang, X., Chang, Q., et al. (2022) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-022-02490-3 · Cited by 14

Set2 histone methyltransferase regulates transcription coupled-nucleotide excision repair in yeast

Selvam, K., Plummer, D. A., Mao, P., & Wyrick, J. J. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010085 · Cited by 14

Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice

He, Y., Yang, W., Huang, L., van Mever, M., Ramautar, R., Harms, A. C., Rijksen, Y., Brandt, R. M. C., Barnhoorn, S., Smit, K., et al. (2024) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13433 · Cited by 13

The roles of lncRNAs in the development of drug resistance of oral cancers

Wang, W., Liu, Y., & Wu, J. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117458 · Cited by 13

Transcription-Coupled Nucleotide Excision Repair: A Faster Solution or the Only Option?

Khobta, A., & Sarmini, L. (2025) · Biomolecules · doi:10.3390/biom15071026 · Cited by 14

LAP2α preserves genome integrity through assisting RPA deposition on damaged chromatin

Bao, K., Zhang, Q., Liu, S., Song, N., Guo, Q., Liu, L., Tian, S., Hao, J., Zhu, Y., Zhang, K., et al. (2022) · Genome biology · doi:10.1186/s13059-022-02638-6 · Cited by 13

The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside

Birkisdóttir, M. B., van Galen, I., Brandt, R. M. C., Barnhoorn, S., van Vliet, N., van Dijk, C., Nagarajah, B., Imholz, S., van Oostrom, C. T., Reiling, E., et al. (2022) · Frontiers in Aging · doi:10.3389/fragi.2022.1005322 · Cited by 13

DNA Damage-Induced RNAPII Degradation and Its Consequences in Gene Expression

Muñoz, J. C., Beckerman, I., Choudhary, R., Bouvier, L. A., & Muñoz, M. J. (2022) · Genes · doi:10.3390/genes13111951 · Cited by 13

Deep intronic founder mutations identified in the ERCC4 / XPF gene are potential therapeutic targets for a high-frequency form of xeroderma pigmentosum

Senju, C., Nakazawa, Y., Oso, T., Shimada, M., Kato, K., Matsuse, M., Tsujimoto, M., Masaki, T., Miyazaki, Y., Fukushima, S., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2217423120 · Cited by 13

The ARK2N–CK2 complex initiates transcription-coupled repair through enhancing the interaction of CSB with lesion-stalled RNAPII

Luo, Y., Li, J., Li, X., Lin, H., Mao, Z., Xu, Z., Li, S., Nie, C., Zhou, X. A., Liao, J., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2404383121 · Cited by 12

A blood-based DNA damage signature in patients with Parkinson’s disease is associated with disease progression

Sproviero, D., Payán‐Gómez, C., Milanese, C., Barnhoorn, S., Sun, S., Gyenis, Á., Delia, D., Lashley, T., Hoeijmakers, J. H. J., Vijg, J., et al. (2025) · Nature Aging · doi:10.1038/s43587-025-00926-x · Cited by 12

UVC radiation intensity dependence of pathogen decontamination rate: semiclassical theory and experiment

Enaki, N. A., Paslari, T., Bazgan, S., Starodub, E., Munteanu, I., Ţurcan, M., Eremeev, V., Profir, A., & Mihailescu, I. N. (2022) · The European Physical Journal Plus · doi:10.1140/epjp/s13360-022-03252-y · Cited by 12

Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy

Huang, Y., Gu, L., & Li, G. (2023) · Cell Discovery · doi:10.1038/s41421-023-00601-8 · Cited by 12

DNA lesion bypass and the stochastic dynamics of transcription-coupled repair

Nicholson, M. D., Anderson, C. J., Odom, D. T., Aitken, S. J., & Taylor, M. S. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2403871121 · Cited by 12

Tobacco-specific nitrosamine 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal (NNA) causes DNA damage and impaired replication/transcription in human lung cells

Sarker, A. H., & Hang, B. (2022) · PLoS ONE · doi:10.1371/journal.pone.0267839 · Cited by 12

Repair, Removal, and Shutdown: It All Hinges on RNA Polymerase II Ubiquitylation

Son, K., & Schärer, O. D. (2020) · Cell · doi:10.1016/j.cell.2020.02.053 · Cited by 12

Development and validation of a DNA repair gene signature for prognosis prediction in Colon Cancer

Wang, X., Tan, C., Ye, M., Weng, W., Weng, W., Zhang, M., Ni, S., Wang, L., Huang, D., Huang, Z., et al. (2020) · Journal of Cancer · doi:10.7150/jca.46328 · Cited by 12

Molecular model of TFIIH recruitment to the transcription-coupled repair machinery

Paul, T., Yan, C., Yu, J., Tsutakawa, S. E., Tainer, J. A., Wang, D., & Ivanov, I. N. (2025) · Nature Communications · doi:10.1038/s41467-025-57593-0 · Cited by 11

R-LOOPs on Short Tandem Repeat Expansion Disorders in Neurodegenerative Diseases

Wu, Y., Song, T., & Xu, Q. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03531-4 · Cited by 11

Opposite roles of transcription elongation factors Spt4/5 and Elf1 in RNA polymerase II transcription through B-form versus non-B DNA structures

Xu, J., Chong, J. P. C., & Wang, D. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab240 · Cited by 11

Impact of DNA sequences in the DNA duplex opening by the Rad4/XPC nucleotide excision repair complex

Paul, D., Mu, H., Tavakoli, A., Dai, Q., Chakraborty, S., He, C., Ansari, A., Broyde, S. B., & Min, J. (2020) · DNA repair · doi:10.1016/j.dnarep.2021.103194 · Cited by 11

Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues

van der Woude, M., Davó-Martínez, C., Thijssen, K. L., Vermeulen, W., & Lans, H. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad642 · Cited by 11

Transcription‐coupled repair – mechanisms of action, regulation, and associated human disorders

Nakazawa, Y., Oka, Y., Matsunaga, T., & Ogi, T. (2024) · FEBS Letters · doi:10.1002/1873-3468.15073 · Cited by 10

Transcription‐coupled repair: tangled up in convoluted repair

Schiffmacher, D. A. L., Pai, Y. J., Pines, A., & Vermeulen, W. (2025) · FEBS Journal · doi:10.1111/febs.70104 · Cited by 10

Dynamic regulation of P-TEFb by 7SK snRNP is integral to the DNA damage response to regulate chemotherapy sensitivity

Fang, Y., Wang, Y., Spector, B. M., Xiao, X. H., Yang, C., Li, P., Yuan, Y., Ding, P., Xiao, Z. J., Zhang, P., et al. (2022) · iScience · doi:10.1016/j.isci.2022.104844 · Cited by 10

BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy

Soni, A., Lin, X., Mladenov, E., Mladenova, V., Stuschke, M., & Iliakis, G. E. (2022) · Cancers · doi:10.3390/cancers14225619 · Cited by 10

Ultrasensitive DNA methyltransferase activity sensing and inhibitor evaluation with highly photostable upconversion nanoparticle transducer

Wu, M., Zhang, M., Fan, Z., Qin, X., Zhu, X., Ji, H., Qin, Y., Wang, Q., & Wu, L. J. (2021) · Microchimica Acta · doi:10.1007/s00604-021-04831-z · Cited by 10

C. elegans survival assays to discern global and transcription-coupled nucleotide excision repair

van der Woude, M., & Lans, H. (2021) · STAR Protocols · doi:10.1016/j.xpro.2021.100586 · Cited by 10

DEF1: Much more than an RNA polymerase degradation factor

Akinniyi, O. T., & Reese, J. C. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103202 · Cited by 10

Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

Birkisdóttir, M. B., Sant, L. J. V., Brandt, R. M. C., Barnhoorn, S., Hoeijmakers, J. H. J., Vermeij, W. P., & Jaarsma, D. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1095801 · Cited by 10

NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells

Aliyaskarova, U., Baiken, Y., Renaud, F., Couvé, S., Kisselev, A. F., Saparbaev, M. K., & Groisman, R. (2023) · Scientific Reports · doi:10.1038/s41598-023-32186-3 · Cited by 10

New roles for elongation factors in RNA polymerase II ubiquitylation and degradation

Reese, J. C. (2023) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2023.194956 · Cited by 10

Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure

Muniesa-Vargas, A., Davó-Martínez, C., Ribeiro-Silva, C., van der Woude, M., Thijssen, K. L., Haspels, B. J., Häckes, D., Kaynak, Ü. U., Kanaar, R., Marteijn, J. A. F., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47935-9 · Cited by 10

UVSSA facilitates transcription-coupled repair of DNA interstrand crosslinks

Liebau, R. C., Waters, C. A., Ahmed, A., Soni, R. K., & Gautier, J. (2024) · DNA repair · doi:10.1016/j.dnarep.2024.103771 · Cited by 10

A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21

Bélanger, F., Roussel, C., Sawchyn, C., St-Hilaire, E., Gezzar-Dandashi, S., Kimenyi Ishimwe, A. B., Mallette, F. A., Wurtele, H., & Drobetsky, E. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.104900 · Cited by 9

ATP-Dependent Chromatin Remodeler CSB Couples DNA Repair Pathways to Transcription with Implications for Cockayne Syndrome and Cancer Therapy

Bilkis, R., Lake, R. J., & Fan, H.-Y. (2025) · Cells · doi:10.3390/cells14040239 · Cited by 9

Nanorate sequencing reveals the Arabidopsis somatic mutation landscape

Meyer, C. A., Nelms, B. D., & Schmitz, R. J. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2514194122 · Cited by 9

Hierarchical mechanisms control the clearance of DNA lesion–stalled RNA polymerase II

van der Meer, P. J., Yakoub, G., Tsukada, K., Nakazawa, Y., Ogi, T., & Luijsterburg, M. S. (2026) · Nature Communications · doi:10.1038/s41467-026-68413-4 · Cited by 9

Effects of replication domains on genome-wide UV-induced DNA damage and repair

Huang, Y., Azgari, C., Yin, M., Chiou, Y., Lindsey‐Boltz, L. A., Sancar, A., Hu, J., & Adebalı, O. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010426 · Cited by 9

Neuroprotective Effect of Abelmoschus manihot Flower Extracts against the H2O2-Induced Cytotoxicity, Oxidative Stress and Inflammation in PC12 Cells

Wang, S., Chang, C., Hsuan, C., Chang, T.-H., Chen, Y., Wang, Y.-Y., Yu, T., Wu, C., & Houng, J. (2022) · Bioengineering · doi:10.3390/bioengineering9100596 · Cited by 9

Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress

Sandoz, J., Cigrang, M., Zachayus, A., Catez, P., Donnio, L., Elly, C., Nieminuszczy, J., Berico, P., Braun, C., Alekseev, S., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-35922-5 · Cited by 9

Genome-wide maps of UVA and UVB mutagenesis in yeast reveal distinct causative lesions and mutational strand asymmetries

Laughery, M. F., Plummer, D. A., Wilson, H. E., Vandenberg, B. N., Mitchell, D., Mieczkowski, P. A., Roberts, S. A., & Wyrick, J. J. (2023) · Genetics · doi:10.1093/genetics/iyad086 · Cited by 9

Progress in 7SK ribonucleoprotein structural biology

Camara, M. B., Sobeh, A. M., & Eichhorn, C. D. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1154622 · Cited by 8

Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice

Barnhoorn, S., Meima, M. E., Peeters, R. P., Darras, V., Leeuwenburgh, S., Hoeijmakers, J. H. J., Vermeij, W. P., & Visser, W. E. (2023) · European Thyroid Journal · doi:10.1530/etj-22-0231 · Cited by 8

Ataxia telangiectasia and Rad3-related (ATR) inhibition by VE-822 potently reversed 5-flourouracil resistance in colorectal cancer cells through targeting DNA damage response

Mihanfar, A., Asghari, F., & Majidinia, M. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09431-7 · Cited by 8

Increased transcriptional elongation and RNA stability of GPCR ligand binding genes unveiled via RNA polymerase II degradation

Bao, L., Zhu, J., Shi, T., Jiang, Y., Li, B., Huang, J. S., & Ji, X. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae478 · Cited by 8

Transcription elongation of the plant RNA polymerase IV is prone to backtracking

Fang, C., Huang, K., Wu, X., Zhang, H., Gu, Z., Wang, J., & Zhang, Y. (2024) · Science Advances · doi:10.1126/sciadv.adq3087 · Cited by 8

Causes and consequences of DNA double-stranded breaks in cardiovascular disease

Marian, A. J. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05131-9 · Cited by 8

Reaction Pathway Sampling and Free-Energy Analyses for Multimeric Protein Complex Disassembly by Employing Hybrid Configuration Bias Monte Carlo/Molecular Dynamics Simulation

Kurisaki, I., & Tanaka, S. (2021) · ACS Omega · doi:10.1021/acsomega.0c05579 · Cited by 8

Live-cell imaging of endogenous CSB-mScarletI as a sensitive marker for DNA-damage-induced transcription stress

Zhou, D., Yu, Q. S., Janssens, R. C., & Marteijn, J. A. F. (2024) · Cell Reports Methods · doi:10.1016/j.crmeth.2023.100674 · Cited by 8

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions

Rodriguez-Alvarez, M., Kim, D. V., & Khobta, A. (2020) · Biomolecules · doi:10.3390/biom10060902 · Cited by 8

Aicardi–Goutières syndrome with SAMHD1 deficiency can be diagnosed by unscheduled DNA synthesis test

Senju, C., Nakazawa, Y., Shimada, M., Iwata, D., Matsuse, M., Tanaka, K., Miyazaki, Y., Moriwaki, S., Mitsutake, N., & Ogi, T. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.1048002 · Cited by 8

High expression of ADAR mediated by OGT promotes chemoresistance in colorectal cancer through the A-to-I editing pathway

Liu, T., Ji, W., Wang, Y., Zhang, Y., Qi, F., & Hang, Q. (2024) · Molecular Genetics and Genomics · doi:10.1007/s00438-024-02197-4 · Cited by 7

Clearance of DNA damage-arrested RNAPII is selectively impaired in Cockayne syndrome cellsPreprint

van der Meer, P. J., Yakoub, G., Nakazawa, Y., Ogi, T., & Luijsterburg, M. S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.17.594644 · Cited by 7

Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damagePreprint

Huang, Z., Luo, S., Wang, Z., Zhang, Z., Jiang, B., Nie, Q. H., & Zhang, J. (2024) · eLife · doi:10.7554/elife.100623 · Cited by 7

Carcinogen-induced DNA adducts amplify APOBEC mutagenesis through nucleotide excision repairPreprint

Durfee, C. C., Stefanovska, B., Wu, R., Caballero, J., Ibrahim, M. A., Carpenter, M. A., Liu, L., Nandi, S. P., Argyris, P. P., Bielo, L. B., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.18.633716 · Cited by 7

Genome-wide maps of UV damage repair and mutation suppression by CPD photolyase

Bohm, K. A., Laughery, M. F., Mieczkowski, P. A., Roberts, S. A., & Wyrick, J. J. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf495 · Cited by 6

Insights Into Cockayne Syndrome Type B: What Underlies Its Pathogenesis?

Afonso‐Reis, R., Madeira, C. R., Brito, D. V. C., & Nóbrega, C. (2025) · Aging Cell · doi:10.1111/acel.70136 · Cited by 6

Extrachromosomal Circular DNA: An Emerging Potential Biomarker for Inflammatory Bowel Diseases?

Petito, V., Vincenzo, F. D., Putignani, L., Abreu, M. T., Regenberg, B., Gasbarrini, A., & Scaldaferri, F. (2024) · Genes · doi:10.3390/genes15040414 · Cited by 6

Role of HSP40 proteins in genome maintenance, insulin signaling and cancer therapy

Huang, Y., & Li, G. (2025) · DNA repair · doi:10.1016/j.dnarep.2025.103839 · Cited by 6

DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population

Niazi, Y., Thomsen, H., Smolková, B., Vodičková, Ľ., Vodenková, S., Kroupa, M., Vymetalkova, V. P., Kažimı́rová, A., Barančoková, M., Volkovová, K., et al. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103079 · Cited by 6

Identification and external validation of a prognostic signature associated with DNA repair genes in gastric cancer

Chen, S., Liu, W., & Huang, Y. (2021) · Scientific Reports · doi:10.1038/s41598-021-86504-8 · Cited by 6

The Prognostic Value of the DNA Repair Gene Signature in Head and Neck Squamous Cell Carcinoma

Ming, R., Wang, E., Wei, J., Shen, J., Zong, S., & Xiao, H. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.710694 · Cited by 6

Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis

Michel, N., Raimer, H. M., Atkin, N. D., Arshad, U., Al-Humadi, R. N., Singh, S., Manukyan, A., Gore, L. N., Burbulis, I. E., Wang, Y., et al. (2022) · Scientific Reports · doi:10.1038/s41598-022-16516-5 · Cited by 6

Size- and Stereochemistry-Dependent Transcriptional Bypass of DNA Alkyl Phosphotriester Adducts in Mammalian Cells

Tan, Y., Wu, J., Clabaugh, G., Li, L., Du, H., & Wang, Y. (2022) · DNA · doi:10.3390/dna2040016 · Cited by 6

A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases

Magraner-Pardo, L., Laskowski, R. A., Pons, T., & Thornton, J. M. (2021) · Scientific Reports · doi:10.1038/s41598-021-93715-6 · Cited by 6

Simulation toolkits at the molecular scale for trans-scale thermal signaling

Kurisaki, I., & Suzuki, M. (2023) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2023.03.040 · Cited by 6

The ELOF(1)ant in the room of TCR

Carnie, C. J., & Jackson, S. P. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00698-7 · Cited by 6

Trichothiodystrophy-causative pathogenic variants impair a cooperative action of TFIIH and DDX1 in R-loop processing

Ferri, D., Branca, G., Lanzafame, M., Gandolfi, E., Riva, V., Maga, G., Nardò, T., Landi, C., Bini, L., Arseni, L., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf745 · Cited by 5

From Genome to Geroscience: How DNA Damage Shapes Systemic Decline

Siametis, A., & Garinis, G. A. (2025) · BioEssays · doi:10.1002/bies.70051 · Cited by 5

Mechanisms of transcription-coupled repair and DNA damage surveillance in health and disease

van Sluis, M., Gonzalo-Hansen, C., Li, Q., Lans, H., Wang, D., & Marteijn, J. A. F. (2025) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-025-00915-3 · Cited by 21

Dealing with transcription-blocking DNA damage: Repair mechanisms, RNA polymerase II processing and human disorders

Jia, N., Guo, C., Nakazawa, Y., van den Heuvel, D., Luijsterburg, M. S., & Ogi, T. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103192 · Cited by 50

What happens at the lesion does not stay at the lesion: Transcription-coupled nucleotide excision repair and the effects of DNA damage on transcription in cis and trans

Geijer, M. E., & Marteijn, J. A. F. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.08.007 · Cited by 64

Molecular basis of transcriptional pausing, stalling, and transcription-coupled repair initiation

Oh, J., Xu, J., Chong, J. P. C., & Wang, D. (2020) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2020.194659 · Cited by 30

Transcription-coupled nucleotide excision repair: New insights revealed by genomic approaches

Duan, M., Speer, R. M., Ulibarri, J., Liu, K. J., & Mao, P. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103126 · Cited by 54