Vermeulen, Wim

Understanding nucleotide excision repair and its roles in cancer and ageing

Marteijn, J. A., Lans, H., Vermeulen, W., & Hoeijmakers, J. H. J. (2014) · Nature Reviews Molecular Cell Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 1,192

ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes

Troelstra, C., van Gool, A., de Wit, J., Vermeulen, W., Bootsma, D., & Hoeijmakers, J. H. J. (1992) · Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 729

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

Niedernhofer, L. J., Garinis, G. A., Raams, A., Lalai, A. S., Robinson, A. R., Appeldoorn, E., Odijk, H., Oostendorp, R., Ahmad, A., van Leeuwen, W., et al. (2006) · Nature

Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms

Cited by 669

RETRACTED: Cockayne Syndrome A and B Proteins Differentially Regulate Recruitment of Chromatin Remodeling and Repair Factors to Stalled RNA Polymerase II In Vivo

Fousteri, M., Vermeulen, W., van Zeeland, A. A., & Mullenders, L. H. F. (2006) · Molecular Cell

DNA Repair MechanismsChromatin Remodeling and Cancer

Cited by 387

The DNA damage response to transcription stress

Lans, H., Hoeijmakers, J. H. J., Vermeulen, W., & Marteijn, J. A. (2019) · Nature Reviews Molecular Cell Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 321

Coordination of dual incision and repair synthesis in human nucleotide excision repair

Staresincic, L., Fagbemi, A. F., Enzlin, J. H., Gourdin, A. M., Wijgers, N., Dunand‐Sauthier, I., Giglia‐Mari, G., Clarkson, S. G., Vermeulen, W., & Schärer, O. D. (2009) · The EMBO Journal

DNA Repair MechanismsNuclear Structure and Function

Cited by 287

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

Schwertman, P., Lagarou, A., Dekkers, D. H. W., Raams, A., van der Hoek, A. C., Laffeber, C., Hoeijmakers, J. H. J., Demmers, J. A. A., Fousteri, M., Vermeulen, W., et al. (2012) · Nature Genetics

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 279

Heterochromatin protein 1 is recruited to various types of DNA damage

Luijsterburg, M. S., Dinant, C., Lans, H., Stap, J., Wiernasz, E., Lagerwerf, S., Warmerdam, D. O., Lindh, M., Brink, M. C., Dobrucki, J. W., et al. (2009) · Journal of Cell Biology

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 264

The core spliceosome as target and effector of non-canonical ATM signalling

Tresini, M., Warmerdam, D. O., Kolovos, P., Snijder, L., Vrouwe, M. G., Demmers, J. A. A., van IJcken, W. F. J., Grosveld, F. G., Medema, R. H., Hoeijmakers, J. H. J., et al. (2015) · Nature

RNA Research and SplicingDNA Repair Mechanisms

Cited by 252

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Marteijn, J. A., Bekker-Jensen, S., Mailand, N., Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, J., & Vermeulen, W. (2009) · Journal of Cell Biology

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 184

Mammalian Transcription-Coupled Excision Repair

Vermeulen, W., & Fousteri, M. (2013) · Cold Spring Harbor Perspectives in Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 184

Global Regulation of Promoter Melting in Naive Lymphocytes

Kouzine, F., Wojtowicz, D., Yamane, A., Resch, W., Kieffer-Kwon, K.-R., Bandle, R., Nelson, S., Nakahashi, H., Awasthi, P., Feigenbaum, L., et al. (2013) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 154

Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions

Rademakers, S., Volker, M., Hoogstraten, D., Nigg, A. L., Moné, M. J., van Zeeland, A. A., Hoeijmakers, J. H. J., Houtsmuller, A. B., & Vermeulen, W. (2003) · Molecular and Cellular Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 149

Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC

Hoogstraten, D., Bergink, S., Ng, J. M. Y., Verbiest, V. H. M., Luijsterburg, M. S., Geverts, B., Raams, A., Dinant, C., Hoeijmakers, J. H. J., Vermeulen, W., et al. (2008) · Journal of Cell Science

DNA Repair MechanismsNuclear Structure and Function

Cited by 122

Stochastic and reversible assembly of a multiprotein DNA repair complex ensures accurate target site recognition and efficient repair

Luijsterburg, M. S., von Bornstaedt, G., Gourdin, A. M., Politi, A. Z., Moné, M. J., Warmerdam, D. O., Goedhart, J., Vermeulen, W., van Driel, R., & Höfer, T. (2010) · Journal of Cell Biology

DNA Repair MechanismsDiffusion and Search Dynamics

Cited by 121

Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC

Luijsterburg, M. S., Goedhart, J., Moser, J., Kool, H., Geverts, B., Houtsmuller, A. B., Mullenders, L. H. F., Vermeulen, W., & van Driel, R. (2007) · Journal of Cell Science

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 105

An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria

Andressoo, J.-O., Mitchell, J. R., de Wit, J., Hoogstraten, D., Volker, M., Toussaint, W., Speksnijder, E., Beems, R. B., van Steeg, H., Jans, J., et al. (2006) · Cancer Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 78

UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells

Nishi, R., Alekseev, S., Dinant, C., Hoogstraten, D., Houtsmuller, A. B., Hoeijmakers, J. H. J., Vermeulen, W., Hanaoka, F., & Sugasawa, K. (2009) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

Cited by 76

Phosphorylation of XPB helicase regulates TFIIH nucleotide excision repair activity

Coin, F., Auriol, J., Tapias, A., Clivio, P., Vermeulen, W., & Egly, J. (2004) · The EMBO Journal

DNA Repair MechanismsNuclear Structure and Function

Cited by 75

DNA damage repair: anytime, anywhere?

Essers, J., Vermeulen, W., & Houtsmuller, A. B. (2006) · Current Opinion in Cell Biology

DNA Repair MechanismsNuclear Structure and Function

Cited by 67

UVSSA and USP7, a new couple in transcription-coupled DNA repair

Schwertman, P., Vermeulen, W., & Marteijn, J. A. (2013) · Chromosoma

DNA Repair MechanismsNuclear Structure and Function

Cited by 49

Cellular Concentrations of DDB2 Regulate Dynamic Binding of DDB1 at UV-Induced DNA Damage

Alekseev, S., Luijsterburg, M. S., Pines, A., Geverts, B., Mari, P.-O., Giglia-Mari, G., Lans, H., Houtsmuller, A. B., Mullenders, L. H. F., Hoeijmakers, J. H. J., et al. (2008) · Molecular and Cellular Biology

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 38

Spatial organization of nucleotide excision repair proteins after UV-induced DNA damage in the human cell nucleus

Solimando, L., Luijsterburg, M. S., Vecchio, L., Vermeulen, W., van Driel, R., & Fakan, S. (2009) · Journal of Cell Science

DNA Repair MechanismsNuclear Structure and Function

Cited by 37

The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Llerena Schiffmacher, D. A., Lee, S.-H., Kliza, K. W., Theil, A. F., Akita, M., Helfricht, A., Bezstarosti, K., Gonzalo-Hansen, C., van Attikum, H., Verlaan-de Vries, M., et al. (2024) · Nature Communications

DNA Repair MechanismsUbiquitin and proteasome pathways

Cited by 19