Environmental–genetic interactions in ageing and dementia across Latin America
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Gene-environment interactions are crucial to developing therapies and interventions and are extensively researched in the global south.
“Gene–environment interactions, which are crucial to the development of therapies and interventions, are the subject of extensive research in the global south48.”
From Resilience and brain health in global populations (2025) · cites this paper as [48]
The Abstract says studying environmental–genetic interactions in Latin America is important for developing better dementia prevention and treatment strategies. It does not establish that such interactions are already extensively researched across the global south; instead, it calls for further research in Latin America. No page number is available in our copy. (LLM, conf=0.88)
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Risk factors for dementia in Brazil: differences by region and race
Suemoto, C. K., Mukadam, N., Brucki, S. M. D., Caramelli, P., Nitrini, R., Laks, J., Livingston, G., & Ferri, C. P. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.12820 · Cited by 93 · see citing works
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The exposome of healthy and accelerated aging across 40 countries
Hernandez, H., Santamaria-Garcia, H., Moguilner, S., Farina, F. R., Legaz, A., Prado, P., Cuadros, J., Gonzalez, L., Gonzalez-Gomez, R., Migeot, J., et al. (2025) · Nature Medicine · doi:10.1038/s41591-025-03808-2 · Cited by 71 · see citing works
Resilience and brain health in global populations
Udeh-Momoh, C. T., Migeot, J., Blackmon, K., Mielke, M. M., Melloni, M., Cox, L., Yaffe, K., Santamaria-Garcia, H., Stern, Y., & Ibanez, A. (2025) · Nature Medicine · doi:10.1038/s41591-025-03846-w · Cited by 42 · see citing works
Self-citationLegaz, A., Altschuler, F., Gonzalez-Gomez, R., Hernández, H., Baez, S., Migeot, J., Fittipaldi, S., Medel, V., Maito, M. A., Godoy, M. E., et al. (2024) · Nature Aging · doi:10.1038/s43587-024-00781-2 · Cited by 36 · see citing works
Self-citationInspired by struggle: A personal journey to global precision brain health
Ibanez, A. (2025) · iScience · doi:10.1016/j.isci.2025.111918 · Cited by 5 · see citing works
- Authors
- Ibanez, A., & Slachevsky, A.
- Affiliations
- Clínica Alemana (CL)
- Corresponding author
- Slachevsky, Andrea
- Venue
- Nature Reviews Neurology
- Published
- 2024-07-12
- Volume
- 20
- Issue
- 10
- Pages
- 571-572
- ISSN
- 1759-4758 (ISSN-L)
- 1759-4766
- PMC
- PMC12010399
- OpenAlex
- W4400585088
- Cited by
- 15
- References
- 1
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 1
- FWCI
- 4.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Nature Reviews Neurology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Universidad de Chile (submittedVersion, cc-by-nc-nd)
- Funders
- Alzheimer's Association (20-725707, SG-20- 725707)
- Agencia Nacional de Investigación y Desarrollo (ANID/PIA/ANILLOS ACT210096, ACT210096, FONDAP-15150012, PIA/ANILLOS ACT210096, 15150012, 1210195, 1210622, 1210176, 1220995)
- National Institutes of Health (15150012)
- National Institute on Aging (R01AG012101, R01AG057234, P01AG019724, R01AG075775)
- Fogarty International Center
- Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (15150012)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Social Sciences › Health › Health disparities and outcomes
- Keywords
- dementia, aging, social determinants of health, Latin America, dementia prevalence, lifestyle intervention, health care access
- MeSH terms
- Aging, Dementia, Humans, Latin America, Gene-Environment Interaction
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