Why is pancreatic cancer so deadly? The pathologist's view
Open accessAbstract
The remarkable aggressiveness of pancreatic cancer has never been fully explained. Although clearly multifactorial, we postulate that venous invasion, a finding seen in most pancreatic cancers but not in most cancers of other organs, may be a significant, underappreciated contributor to the aggressiveness of this disease. Copyright © 2019 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
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Classical prognostic factors such as lymph node status and AJCC stage are not entirely relevant in some long-term survivors of pancreatic cancer.
“However, classical prognostic factors, such as lymph node status and American Joint Committee on Cancer (AJCC) stage, are not entirely relevant in some long-term survivors 201,202.”
From Artificial intelligence in pancreatic cancer (2022) · cites this paper as [202]
Biological features such as early lymph node metastases and venous invasion, even in small cancers, make early detection particularly difficult.
“biological characteristics, such as early lymph node metastases and venous invasion even with small cancers 107, make early detection efforts particularly challenging.”
Cites
Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590 · see citing works
Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219 · see citing works
Siegel, R. L., Miller, K. D., & Jemal, A. (2018) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21442 · Cited by 16,632 · see citing works
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
Le, D. T., Uram, J. N., Wang, H., Bartlett, B. R., Kemberling, H., Eyring, A. D., Skora, A. D., Luber, B. S., Azad, N. S., Laheru, D., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1500596 · Cited by 9,377 · see citing works
Self-citationCore Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
Jones, S., Zhang, X., Parsons, D. W., Lin, J. C.-H., Leary, R. J., Angenendt, P., Mankoo, P., Carter, H., Kamiyama, H., Jimeno, A., et al. (2008) · Science · doi:10.1126/science.1164368 · Cited by 3,969 · see citing works
Self-citationFOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer
Conroy, T., Hammel, P., Hebbar, M., Ben Abdelghani, M., Wei, A. C., Raoul, J.-L., Choné, L., Francois, E., Artru, P., Biagi, J. J., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1809775 · Cited by 2,874 · see citing works
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
Topalian, S. L., Taube, J. M., Anders, R. A., & Pardoll, D. M. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2016.36 · Cited by 2,733 · see citing works
A Randomized Trial of Chemoradiotherapy and Chemotherapy after Resection of Pancreatic Cancer
Neoptolemos, J. P., Stocken, D. D., Friess, H., Bassi, C., Dunn, J., Hickey, H., Beger, H. G., Fernández‐Cruz, L., Dervenis, C., LACAINE, F., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032295 · Cited by 2,709 · see citing works
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
Yachida, S., Jones, S., Bozic, I., Antal, T., Leary, R., Fu, B., Kamiyama, M., Hruban, R. H., Eshleman, J. R., Nowak, M. A., et al. (2010) · Nature · doi:10.1038/nature09515 · Cited by 2,502 · see citing works
Self-citationEMT and Dissemination Precede Pancreatic Tumor Formation
Rhim, A. D., Mirek, E. T., Aiello, N. M., Maitra, A., Bailey, J. M., McAllister, F., Reichert, M., Beatty, G. L., Rustgi, A. K., Vonderheide, R. H., et al. (2012) · Cell · doi:10.1016/j.cell.2011.11.025 · Cited by 2,136 · see citing works
Integrated genomic characterization of pancreatic ductal adenocarcinoma
Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., et al. (2017) · Cancer Cell · doi:10.1016/j.ccell.2017.07.007 · Cited by 2,019 · see citing works
Self-citationKleeff, J., Korc, M., Apte, M., La Vecchia, C., Johnson, C. D., Biankin, A. V., Neale, R. E., Tempero, M., Tuveson, D. A., Hruban, R. H., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.22 · Cited by 1,982 · see citing works
Self-citationBrabletz, T., Kalluri, R., Nieto, M. A., & Weinberg, R. A. (2018) · Nature Reviews Cancer · doi:10.1038/nrc.2017.118 · Cited by 1,961 · see citing works
Neoptolemos, J. P., Palmer, D. H., Ghaneh, P., Psarelli, E. E., Valle, J. W., Halloran, C. M., Faluyi, O. O., O'Reilly, D. A., Cunningham, D., Wadsley, J., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(16)32409-6 · Cited by 1,941 · see citing works
1423 Pancreaticoduodenectomies for Pancreatic Cancer: A Single-Institution Experience
Winter, J. M., Cameron, J. L., Campbell, K. A., Arnold, M. A., Chang, D. C., Coleman, J., Hodgin, M. B., Sauter, P. K., Hruban, R. H., Riall, T. S., et al. (2006) · Journal of Gastrointestinal Surgery · doi:10.1016/j.gassur.2006.08.018 · Cited by 1,491 · see citing works
Self-citationNeoptolemos, J. P., Stocken, D. D., Bassi, C., Ghaneh, P., Cunningham, D., Goldstein, D., Padbury, R., Moore, M. J., Gallinger, S., Mariette, C., et al. (2010) · JAMA · doi:10.1001/jama.2010.1275 · Cited by 1,395 · see citing works
Biffi, G., Oni, T. E., Spielman, B., Hao, Y., Elyada, E., Park, Y., Preall, J., & Tuveson, D. A. (2019) · Cancer Discovery · doi:10.1158/2159-8290.cd-18-0710 · Cited by 1,360 · see citing works
The Pancreas Cancer Microenvironment
Feig, C., Gopinathan, A., Neesse, A., Chan, D. S., Cook, N., & Tuveson, D. A. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-3114 · Cited by 1,316 · see citing works
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer
Initiative, A. P. C. G., Balachandran, V. P., Łuksza, M., Zhao, J. N., Makarov, V., Moral, J. A., Remark, R., Herbst, B., Askan, G., Bhanot, U., et al. (2017) · Nature · doi:10.1038/nature24462 · Cited by 1,191 · see citing works
Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer
Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschênes, A., Somerville, T. D. D., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G.-H., et al. (2018) · Cancer Discovery · doi:10.1158/2159-8290.cd-18-0349 · Cited by 1,092 · see citing works
Self-citationIacobuzio-Donahue, C. A., Fu, B., Yachida, S., Luo, M., Abe, H., Henderson, C. M., Vilardell, F., Wang, Z., Keller, J. W., Banerjee, P., et al. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.17.7188 · Cited by 1,081 · see citing works
Self-citationTaube, J. H., Herschkowitz, J. I., Komurov, K., Zhou, A. Y., Gupta, S. K., Yang, J., Hartwell, K. A., Önder, T. T., Gupta, P. B., Evans, K. W., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004900107 · Cited by 1,041 · see citing works
de Azambuja, E., Cardoso, F., de Castro, G., Colozza, M., Mano, M. S., Durbecq, V., Sotiriou, C. P., Larsimont, D., Piccart, M. J., & Paesmans, M. (2007) · British Journal of Cancer · doi:10.1038/sj.bjc.6603756 · Cited by 954 · see citing works
Basturk, O., Hong, S.-M., Wood, L. D., Adsay, N. V., Albores-Saavedra, J., Biankin, A. V., Brosens, L. A. A., Fukushima, N., Goggins, M., Hruban, R. H., et al. (2015) · American Journal of Surgical Pathology · doi:10.1097/pas.0000000000000533 · Cited by 864 · see citing works
Self-citationImmune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
Ino, Y., Yamazaki–Itoh, R., Shimada, K., Iwasaki, M., Kosuge, T., Kanai, Y., & Hiraoka, N. (2013) · British Journal of Cancer · doi:10.1038/bjc.2013.32 · Cited by 853 · see citing works
Comparative lesion sequencing provides insights into tumor evolution
Jones, S., Chen, W.-D. D., Parmigiani, G., Diehl, F., Beerenwinkel, N., Tibor Antal, A., Traulsen, A., Nowak, M. A., Siegel, C., Velculescu, V. E., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712345105 · Cited by 817 · see citing works
Rinehart, J., Adjei, A. A., LoRusso, P. M., Waterhouse, D., Hecht, J. R., Natale, R. B., Hamid, O., Varterasian, M., Asbury, P., Kaldjian, E. P., et al. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2004.01.185 · Cited by 645 · see citing works
Carstens, J. L., Correa de Sampaio, P., Yang, D., Barua, S., Wang, H., Rao, A., Allison, J. P., LeBleu, V. S., & Kalluri, R. (2017) · Nature Communications · doi:10.1038/ncomms15095 · Cited by 633 · see citing works
Stromal biology and therapy in pancreatic cancer: a changing paradigm
Neeße, A., Algül, H., Tuveson, D. A., & Gress, T. M. (2015) · Gut · doi:10.1136/gutjnl-2015-309304 · Cited by 562 · see citing works
Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A. I., Kawashima, R., Choe, G. H., Sauer, D., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.03.037 · Cited by 555 · see citing works
The NANETS Consensus Guideline for the Diagnosis and Management of Neuroendocrine Tumors
Boudreaux, J. P., Klimstra, D. S., Hassan, M. M., Woltering, E. A., Jensen, R. T., Goldsmith, S. J., Nutting, C. W., Bushnell, D. L., Caplin, M. E., & Yao, J. C. (2010) · Pancreas · doi:10.1097/mpa.0b013e3181ebb2a5 · Cited by 536 · see citing works
Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
Alexandrov, L. B., & Stratton, M. R. (2014) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2013.11.014 · Cited by 488 · see citing works
ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum
Niederle, B., Pape, U.-F., Costa, F., Gross, D., Kelestimur, F., Knigge, U., Öberg, K., Pavel, M., Perren, A., Toumpanakis, C., et al. (2016) · Neuroendocrinology · doi:10.1159/000443170 · Cited by 474 · see citing works
Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma
Shindo, K., Yu, J., Suenaga, M., Fesharakizadeh, S., Cho, C., Macgregor-Das, A., Siddiqui, A., Witmer, P. D., Tamura, K., Song, T. J., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2017.72.3502 · Cited by 458 · see citing works
Self-citationPrognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer
Pawlik, T. M., Gleisner, A., Cameron, J. L., Winter, J. M., Assumpcao, L., Lillemoe, K. D., Wolfgang, C. L., Hruban, R. H., Schulick, R. D., Yeo, C. J., et al. (2007) · Surgery · doi:10.1016/j.surg.2006.12.013 · Cited by 453 · see citing works
Self-citationHaeno, H., Gönen, M., Davis, M. B., Herman, J. M., Iacobuzio–Donahue, C. A., & Franziska Michor, A. (2012) · Cell · doi:10.1016/j.cell.2011.11.060 · Cited by 408 · see citing works
McAllister, F., Bailey, J. M., Alsina, J., Nirschl, C. J., Sharma, R., Fan, H., Rattigan, Y., Roeser, J. C., Lankapalli, R. H., Zhang, H., et al. (2014) · Cancer Cell · doi:10.1016/j.ccr.2014.03.014 · Cited by 405 · see citing works
Eric, L., Yeo, C. J., Lillemoe, K. D., Biedrzycki, B. A., Kobrin, B. J., Herman, J. M., Sugar, E. A., Piantadosi, S., Cameron, J. L., Solt, S., et al. (2011) · Annals of Surgery · doi:10.1097/sla.0b013e3181fd271c · Cited by 404 · see citing works
Self-citationHepatocytes direct the formation of a pro-metastatic niche in the liver
Lee, J. W., Stone, M. L., Porrett, P. M., Thomas, S. K., Komar, C. A., Li, J. H., Delman, D., Graham, K., Gladney, W. L., Hua, X., et al. (2019) · Nature · doi:10.1038/s41586-019-1004-y · Cited by 402 · see citing works
Imaging diagnosis of pancreatic cancer: A state-of-the-art review
Lee, E. S. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i24.7864 · Cited by 401 · see citing works
<i>SMAD4</i> Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer
Blackford, A., Serrano, O. K., Wolfgang, C. L., Parmigiani, G., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C.-H., Leary, R. J., Eshleman, J. R., et al. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0227 · Cited by 371 · see citing works
Self-citationHiraoka, N., Ino, Y., Yamazaki–Itoh, R., Kanai, Y., Kosuge, T., & Shimada, K. (2015) · British Journal of Cancer · doi:10.1038/bjc.2015.145 · Cited by 364 · see citing works
Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer
Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., et al. (2016) · Cancer Discovery · doi:10.1158/2159-8290.cd-15-0402 · Cited by 361 · see citing works
Self-citationThe Lymph Node Ratio is the Strongest Prognostic Factor after Resection of Pancreatic Cancer
Riediger, H., Keck, T., Wellner, U. F., Hausen, A. Z., Adam, U., Hopt, U. T., & Makowiec, F. (2009) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-009-0919-2 · Cited by 359 · see citing works
Stromal biology and therapy in pancreatic cancer: ready for clinical translation?
Neeße, A., Bauer, C. A., Öhlund, D., Lauth, M., Buchholz, M., Michl, P., Tuveson, D. A., & Gress, T. M. (2018) · Gut · doi:10.1136/gutjnl-2018-316451 · Cited by 348 · see citing works
Hingorani, S. R., Harris, W. P., Beck, J. T., Berdov, B. A., Wagner, S. A., Pshevlotsky, E. M., Tjulandin, S., Gladkov, O. A., Holcombe, R. F., Korn, R. L., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-2010 · Cited by 335 · see citing works
Zhou, P., Li, B., Liu, F.-R., Zhang, M., Wang, Q., Liu, Y., Yao Zong, Y. U. A. N., & Li, D. (2017) · Molecular Cancer · doi:10.1186/s12943-017-0624-9 · Cited by 334 · see citing works
Role of Immune Cells and Immune-Based Therapies in Pancreatitis and Pancreatic Ductal Adenocarcinoma
Zheng, L., Xue, J., Jaffee, E. M., & Habtezion, A. (2013) · Gastroenterology · doi:10.1053/j.gastro.2012.12.042 · Cited by 323 · see citing works
Carpelan-Holmström, M. A., Nordling, S., Pukkala, ., Sankila, R., Lüttges, J., Klöppel, G., & Haglund, C. (2005) · Gut · doi:10.1136/gut.2004.047191 · Cited by 313 · see citing works
Su, C., Tsay, S., Wu, C.-C., Shyr, Y., King, K., Lee, C.-H., Lui, W., Liu, T.-J., & P’eng, F. (1996) · Annals of Surgery · doi:10.1097/00000658-199604000-00007 · Cited by 298 · see citing works
Mechanisms of immune evasion in breast cancer
Bates, J. P., Derakhshandeh, R., Jones, L. P., & Webb, T. J. (2018) · BMC Cancer · doi:10.1186/s12885-018-4441-3 · Cited by 294 · see citing works
Bluemke, D. A., Cameron, J. L., Hruban, R. H., Pitt, H. A., Siegelman, S. S., Soyer, P. A., & Fishman, E. K. (1995) · Radiology · doi:10.1148/radiology.197.2.7480681 · Cited by 290 · see citing works
Self-citationPetrelli, F., Viale, G., Cabiddu, M., & Barni, S. (2015) · Breast Cancer Research and Treatment · doi:10.1007/s10549-015-3559-0 · Cited by 286 · see citing works
Genetic, Immunohistochemical, and Clinical Features of Medullary Carcinoma of the Pancreas
Wilentz, R. E., Goggins, M., Redston, M. S., Marcus, V., Adsay, V. N., Riall, T. S., Kadkol, S. S., Yeo, C. J., Choti, M. A., ZAHURAK, M. L., et al. (2000) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65035-3 · Cited by 281 · see citing works
Self-citationPergolini, I., Sahora, K., Ferrone, C. R., Morales‐Oyarvide, V., Wolpin, B. M., Mucci, L. A., Brugge, W. R., Mino-Kenudson, M. A., Patiño, M., Sahani, D. V., et al. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.07.019 · Cited by 280 · see citing works
Goggins, M., Offerhaus, G. J. A., Hilgers, W., Griffin, C. A., Shekher, M. C., Tang, D. J., Sohn, T. A., Yeo, C. J., Kern, S. E., & Hruban, R. H. (1998) · Europe PMC (PubMed Central) · Cited by 266 · see citing works
Self-citationIntramural and extramural vascular invasion in colorectal cancer
Betge, J., Pollheimer, M. J., Lindtner, R. A., Kornprat, P., Schlemmer, A., Rehak, P., Vieth, M. W., Höefler, G., & Langner, C. (2011) · Cancer · doi:10.1002/cncr.26310 · Cited by 261 · see citing works
Kamarajah, S. K., Burns, W. R., Frankel, T. L., Cho, C. S., & Nathan, H. (2017) · Annals of Surgical Oncology · doi:10.1245/s10434-017-5810-x · Cited by 254 · see citing works
Resected periampullary adenocarcinoma: 5-year survivors and their 6- to 10-year follow-up
Riall, T. S., Cameron, J. L., Lillemoe, K. D., Winter, J. M., Campbell, K. A., Hruban, R. H., Chang, D. C., & Yeo, C. J. (2006) · Surgery · doi:10.1016/j.surg.2006.04.006 · Cited by 246 · see citing works
Self-citationBustreo, S., Osella‐Abate, S., Cassoni, P., Donadio, M., Airoldi, M., Pedani, F., Papotti, M. G., Sapino, A., & Castellano, I. (2016) · Breast Cancer Research and Treatment · doi:10.1007/s10549-016-3817-9 · Cited by 230 · see citing works
Leinonen, M. K., Miettinen, J., Heikkinen, S. M. M., Pitkäniemi, J. M., & Malila, N. K. (2017) · European Journal of Cancer · doi:10.1016/j.ejca.2017.02.017 · Cited by 230 · see citing works
Pancreatic ductal adenocarcinoma: Long-term survival does not equal cure
Ferrone, C. R., Pieretti‐Vanmarcke, R., Bloom, J. P., Zheng, H. W., Szymonifka, J., Wargo, J. A., Thayer, S. P., Lauwers, G. Y., Deshpande, V., Mino-Kenudson, M. A., et al. (2012) · Surgery · doi:10.1016/j.surg.2012.05.020 · Cited by 221 · see citing works
Chatterjee, D., Katz, M. H. G., Rashid, A., Wang, H., Iuga, A. C., Varadhachary, G. R., Wolff, R. A., Lee, J. E., Pisters, P. W. T., Crane, C. H., et al. (2012) · The American Journal of Surgical Pathology · doi:10.1097/pas.0b013e31824104c5 · Cited by 208 · see citing works
Perineural Invasion in Pancreatic Cancer
Hirai, I., Kimura, W., Ozawa, K., Kudo, S., Suto, K., Kuzu, H., & Fuse, A. (2002) · Pancreas · doi:10.1097/00006676-200201000-00003 · Cited by 208 · see citing works
The Prognostic Significance of Micrometastases in Breast Cancer: A SEER Population-Based Analysis
Chen, S. L., Hoehne, F. M., & Giuliano, A. E. (2007) · Annals of Surgical Oncology · doi:10.1245/s10434-007-9513-6 · Cited by 191 · see citing works
Knudsen, E. S., Vail, P. J., Balaji, U., Ngo, H., Botros, I. W., Makarov, V., Riaz, N., Balachandran, V. P., Leach, S. D., Thompson, D. M., et al. (2017) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-17-0162 · Cited by 191 · see citing works
The Pancreatic Cancer Microenvironment
Dougan, S. K. (2017) · The Cancer Journal · doi:10.1097/ppo.0000000000000288 · Cited by 186 · see citing works
Ozaki, H., Hiraoka, T., Mizumoto, R., Matsuno, S., Matsumoto, Y., Nakayama, T., Tsunoda, T., Suzuki, T., Monden, M., Saitoh, Y., et al. (1999) · Surgery Today · doi:10.1007/bf02482964 · Cited by 176 · see citing works
Venous and neural invasion as predictors of recurrence in rectal adenocarcinoma
Horn, A., Dahl, O., & Morild, I. (1991) · Diseases of the Colon & Rectum · doi:10.1007/bf02051074 · Cited by 173 · see citing works
Interstitial Pressure in Pancreatic Ductal Adenocarcinoma Is Dominated by a Gel-Fluid Phase
DuFort, C. C., DelGiorno, K. E., Carlson, M. A., Osgood, R. J., Zhao, C., Huang, Z., Thompson, C. B., Connor, R. J., Thanos, C. D., Scott Brockenbrough, J., et al. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2016.03.040 · Cited by 171 · see citing works
Perineural invasion by ductal adenocarcinoma of the pancreas
Takahashi, T., Ishikura, H., Motohara, T., Okushiba, S., Dohke, M., & Katoh, H. (1997) · Journal of Surgical Oncology · doi:10.1002/(sici)1096-9098(199707)65:3 · Cited by 167 · see citing works
Circulating Tumor Cells Dynamics in Pancreatic Adenocarcinoma Correlate With Disease Status
Gemenetzis, G., Groot, V. P., Yu, J., Ding, D., Teinor, J. A., Javed, A. A., Wood, L. D., Burkhart, R. A., Cameron, J. L., Makary, M. A., et al. (2018) · Annals of Surgery · doi:10.1097/sla.0000000000002925 · Cited by 158 · see citing works
Self-citationSchorn, S., Demir, İ. E., Haller, B., Scheufele, F., Reyes, C. M., Tieftrunk, E., Sargut, M., Göß, R., Friess, H., & Ceyhan, G. O. (2017) · Surgical Oncology · doi:10.1016/j.suronc.2017.01.007 · Cited by 157 · see citing works
Murakami, Y., Uemura, K., Sudo, T., Hayashidani, Y., Hashimoto, Y., Nakashima, A., Yuasa, Y., Kondo, N., Ohge, H., & Sueda, T. (2010) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2010.03.037 · Cited by 155 · see citing works
Perineural invasion of carcinoma of the pancreas and biliary tract
Nagakawa, T., Mori, K. J., Nakano, T., Kadoya, M., Kobayashi, H., Akiyama, T., Kayahara, M., Ohta, T., Ueno, K., Higashino, Y., et al. (1993) · British journal of surgery · doi:10.1002/bjs.1800800526 · Cited by 154 · see citing works
Clinicopathological Aspects of Small Pancreatic Cancer
Egawa, S., Takeda, K., Fukuyama, S., Motoi, F., Sunamura, M., & Matsuno, S. (2004) · Pancreas · doi:10.1097/00006676-200404000-00004 · Cited by 153 · see citing works
Ikeda, D. M., Andersson, I., Wattsgård, C., Janzon, L., & Linell, F. (1992) · American Journal of Roentgenology · doi:10.2214/ajr.159.2.1632342 · Cited by 151 · see citing works
EMT and Treatment Resistance in Pancreatic Cancer
Gaianigo, N., Melisi, D., & Carbone, C. (2017) · Cancers · doi:10.3390/cancers9090122 · Cited by 146 · see citing works
Perspectives in the treatment of pancreatic adenocarcinoma
Cid-Arregui, Á. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i31.9297 · Cited by 142 · see citing works
Foucher, E. D., Ghigo, C., Chouaı̈b, S., Galon, J., Iovanna, J., & Olive, D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01044 · Cited by 139 · see citing works
Klein, W. M., Hruban, R. H., Klein–Szanto, A. J., & Wilentz, R. E. (2002) · Modern Pathology · doi:10.1038/modpathol.3880544 · Cited by 131 · see citing works
Self-citationGroße-Steffen, T., Giese, T., Giese, N. A., Longerich, T., Schirmacher, P., Hänsch, G. M., & Gaida, M. M. (2012) · Clinical and Developmental Immunology · doi:10.1155/2012/720768 · Cited by 131 · see citing works
Self-citationHan, Y., Lee, H., Kang, J. S., Kim, J. R., Kim, H. S., Lee, J. M., Lee, K.-B., Kwon, W., Kim, S., & Jang, J. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.10.013 · Cited by 130 · see citing works
Bi, X., Pohl, N. M., Qian, Z., Yang, G. R., Gou, Y., Guzman, G., Kajdacsy‐Balla, A., Iozzo, R. V., & Yang, W. (2011) · Carcinogenesis · doi:10.1093/carcin/bgr293 · Cited by 128 · see citing works
Neural Invasion in the Staging of Pancreatic Cancer
Pour, P. M., Bell, R. H., & Batra, S. K. (2003) · Pancreas · doi:10.1097/00006676-200305000-00002 · Cited by 122 · see citing works
Precancerous neoplastic cells can move through the pancreatic ductal system
Makohon-Moore, A. P., Matsukuma, K., Zhang, M., Reiter, J. G., Gerold, J. M., Jiao, Y., Sikkema, L., Attiyeh, M. A., Yachida, S., Sandone, C., et al. (2018) · Nature · doi:10.1038/s41586-018-0481-8 · Cited by 120 · see citing works
Self-citationMessenger, D. E., Driman, D. K., & Kirsch, R. (2012) · Human Pathology · doi:10.1016/j.humpath.2011.11.015 · Cited by 118 · see citing works
Does Size Matter in Pancreatic Cancer?
Marchegiani, G., Andrianello, S., Malleo, G., Gregorio, L. D., Scarpa, A., Mino-Kenudson, M. A., Maggino, L., Ferrone, C. R., Lillemoe, K. D., Bassi, C., et al. (2016) · Annals of Surgery · doi:10.1097/sla.0000000000001837 · Cited by 117 · see citing works
Groot, V. P., Gemenetzis, G., Blair, A. B., Ding, D., Javed, A. A., Burkhart, R. A., Yu, J., Rinkes, I. H. M. B., Molenaar, I. Q., Cameron, J. L., et al. (2018) · Annals of Surgical Oncology · doi:10.1245/s10434-018-6558-7 · Cited by 116 · see citing works
Self-citationK-ras mutation in focal proliferative lesions of human pancreas.
Terhune, P. G., Phifer, D. M., Tosteson, T. D., & Longnecker, D. S. (1998) · PubMed · Cited by 114 · see citing works
Luchini, C., Pea, A., Lionheart, G., Mafficini, A., Nottegar, A., Veronese, N., Chianchiano, P. E., Brosens, L. A. A., Noë, M., Offerhaus, G. J. A., et al. (2017) · The Journal of Pathology · doi:10.1002/path.4941 · Cited by 113 · see citing works
Self-citationHaffner, M. C., Weier, C. A., Xu, M., Vaghasia, A. M., Gürel, B., Gümüşkaya, B., Esopi, D., Fedor, H. L., Tan, H., Kulaç, İ., et al. (2015) · The Journal of Pathology · doi:10.1002/path.4628 · Cited by 105 · see citing works
O'Reilly, E. M., Lee, J. W., Lowery, M. A., Capanu, M., Stadler, Z. K., Moore, M. J., Dhani, N. C., Kindler, H. L., Estrella, H., Maynard, H., et al. (2018) · Cancer · doi:10.1002/cncr.31218 · Cited by 103 · see citing works
Dal Molin, M., Zhang, M., de Wilde, R. F., Ottenhof, N. A., Rezaee, N., Wolfgang, C. L., Blackford, A., Vogelstein, B., Kinzler, K. W., Papadopoulos, N., et al. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-2600 · Cited by 101 · see citing works
Self-citationSetälä, L., Kosma, V.-M., Marin, S., Lipponen, P., Mj, E., Syrjänen, K. J., & Alhava, E. (1996) · British Journal of Cancer · doi:10.1038/bjc.1996.434 · Cited by 98 · see citing works
Orchestrating the Tumor Microenvironment to Improve Survival for Patients With Pancreatic Cancer
Whatcott, C. J., Han, H., & Hoff, D. D. V. (2015) · The Cancer Journal · doi:10.1097/ppo.0000000000000140 · Cited by 97 · see citing works
THE ASSESSMENT OF HISTOLOGICAL DIFFERENTIATION IN BREAST CANCER*
Elston, C. W. (1984) · Australian and New Zealand Journal of Surgery · doi:10.1111/j.1445-2197.1984.tb06677.x · Cited by 97 · see citing works
Relationship between tumour size and outcome in pancreatic ductal adenocarcinoma
Ansari, D., Bauden, M. P., Bergström, S., Rylance, R. T., Marko‐Varga, G., & Andersson, R. E. (2017) · British journal of surgery · doi:10.1002/bjs.10471 · Cited by 93 · see citing works
Precancer: A conceptual working definition
Berman, J. J., Albores‐Saavedra, J., Bostwick, D. G., DeLellis, R. A., Eble, J. N., Hamilton, S. R., Hruban, R. H., Mutter, G. L., Page, D. L., Rohan, T. E., et al. (2006) · Cancer Detection and Prevention · doi:10.1016/j.cdp.2006.09.002 · Cited by 93 · see citing works
Self-citationBuck, A. C., Schirrmeister, H., Guhlmann, C. A., Diederichs, C. G., Shen, C., Buchmann, I., Kotzerke, J., Birk, D., Mattfeldt, T., & Reske, S. N. (2001) · PubMed · Cited by 90 · see citing works
Implications for Breast Cancer Restaging Based on the 8th Edition AJCC Staging Manual
Plichta, J. K., Ren, Y., Thomas, S. M., Greenup, R. A., Fayanju, O. M., Rosenberger, L. H., Hyslop, T., & Hwang, E. S. (2018) · Annals of Surgery · doi:10.1097/sla.0000000000003071 · Cited by 90 · see citing works
Tumour volume doubling time of molecular breast cancer subtypes assessed by serial breast ultrasound
Ryu, E. B., Chang, J. M., Seo, M., Kim, S. A., Lim, J., & Moon, W. K. (2014) · European Radiology · doi:10.1007/s00330-014-3256-0 · Cited by 88 · see citing works
Gaida, M. M., Steffen, T., Günther, F. A., Tschaharganeh, D. F., Felix, K., Bergmann, F., Schirmacher, P., & Hänsch, G. M. (2012) · European Journal of Immunology · doi:10.1002/eji.201242628 · Cited by 83 · see citing works
Self-citationMassucco, P., Ribero, D., Sgotto, E., Mellano, A., Muratore, A., & Capussotti, L. (2009) · Annals of Surgical Oncology · doi:10.1245/s10434-009-0672-5 · Cited by 83 · see citing works
Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells
Dioufa, N., Clark, A. M., Ma, B., Beckwitt, C. H., & Wells, A. H. (2017) · Molecular Cancer · doi:10.1186/s12943-017-0740-6 · Cited by 81 · see citing works
Apoptosis pathways and their therapeutic exploitation in pancreatic cancer
Fulda, S. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00748.x · Cited by 72 · see citing works
Kondo, T., Kanai, M., Kou, T., Sakuma, T., Mochizuki, H., Kamada, M., Nakatsui, M., Uza, N., Kodama, Y., Masui, T., et al. (2018) · Oncotarget · doi:10.18632/oncotarget.24865 · Cited by 72 · see citing works
Alam, M. S., Gaida, M. M., Bergmann, F., Lasitschka, F., Giese, T., Giese, N. A., Hackert, T., Hinz, U., Hussain, S. P., Козлов, С. В., et al. (2015) · Nature Medicine · doi:10.1038/nm.3957 · Cited by 66 · see citing works
Self-citationNew insights into perineural invasion of pancreatic cancer: More than pain
Liang, D., Shi, S., Xu, J., Zhang, B., Qin, Y., Ji, S., Xu, W., Liu, J., Liu, L., Liu, C., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2016.01.002 · Cited by 66 · see citing works
Growth Rate of Pancreatic Adenocarcinoma: Initial Clinical Experience
Furukawa, H., Iwata, R., & Moriyama, N. (2001) · Pancreas · doi:10.1097/00006676-200105000-00005 · Cited by 65 · see citing works
Mayer, C., Darb‐Esfahani, S., Meyer, A.-S., Hübner, K., Rom, J., Sohn, C., Braicu, E. I., Sehouli, J., Hänsch, G. M., & Gaida, M. M. (2016) · Journal of Cancer · doi:10.7150/jca.14169 · Cited by 65 · see citing works
Self-citationStanton-Maxey, K. J., Sidner, R. A., Miller, G. A., Cummings, O. W., Schmidt, C. M., Howard, T. J., & Wiebke, E. A. (2003) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2003.07.002 · Cited by 64 · see citing works
Pancreatic adenocarcinoma: insights into patterns of recurrence and disease behavior
Şahin, İ. H., Elias, H. K., Chou, J. F., Capanu, M., & O'Reilly, E. M. (2018) · BMC Cancer · doi:10.1186/s12885-018-4679-9 · Cited by 63 · see citing works
Loehrer, A. P., Chang, D. C., Hutter, M. M., Song, Z., Lillemoe, K. D., Warshaw, A. L., & Ferrone, C. R. (2015) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2015.09.010 · Cited by 59 · see citing works
Suenaga, M., Fujii, T., Kanda, M., Takami, H., OKUMURA, N., Inokawa, Y., Kobayashi, D., Tanaka, C., Yamada, S., Sugimoto, H., et al. (2014) · PubMed · Cited by 59 · see citing works
Pancreatic cancer in Lynch syndrome patients
Bujanda, L., & Herreros-Villanueva, M. (2017) · Journal of Cancer · doi:10.7150/jca.20750 · Cited by 57 · see citing works
Adenocarcinoma of the colon and rectum in patients less than 40 years of age.
Moore, P. A., Dilawari, R. A., & Fidler, W. J. (1984) · PubMed · Cited by 55 · see citing works
Hong, S., Goggins, M., Wolfgang, C. L., Schulick, R. D., Edil, B. H., Cameron, J. L., Handra‐Luca, A., Herman, J. M., & Hruban, R. H. (2011) · The American Journal of Surgical Pathology · doi:10.1097/pas.0b013e3182376e36 · Cited by 54 · see citing works
Self-citationNoë, M., Rezaee, N., Asrani, K. V., Skaro, M. F., Groot, V. P., Wu, P.-H., Olson, M. T., Hong, S., Kim, S. J., Weiss, M. J., et al. (2018) · American Journal Of Pathology · doi:10.1016/j.ajpath.2018.04.002 · Cited by 53 · see citing works
Self-citationPremalignancy in Prostate Cancer: Rethinking What We Know
Marzo, A. M. D., Haffner, M. C., Lotan, T. L., Yegnasubramanian, S., & Nelson, W. G. (2016) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-15-0431 · Cited by 53 · see citing works
Epstein, J. D., Kozak, G. M., Fong, Z. V., He, J. P., Javed, A. A., Joneja, U., Jiang, W., Ferrone, C. R., Lillemoe, K. D., Cameron, J. L., et al. (2017) · Journal of Surgical Oncology · doi:10.1002/jso.24723 · Cited by 53 · see citing works
Nakashima, K., Uematsu, T., Takahashi, K., Nishimura, S., Tadokoro, Y., Hayashi, T., & Sugino, T. (2018) · Breast Cancer · doi:10.1007/s12282-018-0914-0 · Cited by 49 · see citing works
Cancerization of the Pancreatic Ducts
Hutchings, D., Waters, K. M., Weiss, M. J., Wolfgang, C. L., Makary, M. A., He, J. P., Cameron, J. L., Wood, L. D., & Hruban, R. H. (2018) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000001148 · Cited by 47 · see citing works
Self-citationEarly Pancreatic Ductal Adenocarcinoma Survival Is Dependent on Size
Hur, C., Tramontano, A. C., Dowling, E. C., Brooks, G. A., Jeon, A., Brugge, W. R., Gazelle, G. S., Kong, C. Y., & Pandharipande, P. V. (2015) · Pancreas · doi:10.1097/mpa.0000000000000587 · Cited by 46 · see citing works
Voltaggio, L., Cimino‐Mathews, A., Bishop, J. A., Argani, P., Cuda, J. D., Epstein, J. I., Hruban, R. H., Netto, G. J., Stoler, M. H., Taube, J. M., et al. (2016) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21350 · Cited by 46 · see citing works
Self-citationLænkholm, A., Grabau, D. A., Talman, M., Balslev, E., Jylling, A. M. B., Tabor, T. P., Johansen, M. M., Brügmann, A. H., Lelkaitis, G., Caterino, T. D., et al. (2017) · Acta Oncologica · doi:10.1080/0284186x.2017.1404127 · Cited by 44 · see citing works
Lynch syndrome – cancer pathways, heterogeneity and immune escape
Seth, S., Ager, A., Arends, M. J., & Frayling, I. M. (2018) · The Journal of Pathology · doi:10.1002/path.5139 · Cited by 44 · see citing works
Assessment of vascular invasion in gastric cancer: A comparative study
Gresta, L. T. (2013) · World Journal of Gastroenterology · doi:10.3748/wjg.v19.i24.3761 · Cited by 43 · see citing works
He, P. (2002) · World Journal of Gastroenterology · doi:10.3748/wjg.v8.i5.943 · Cited by 43 · see citing works
Tumor characteristics of breast cancer in predicting axillary lymph node metastasis
Chen, D.-R. (2014) · Medical Science Monitor · doi:10.12659/msm.890491 · Cited by 38 · see citing works
Zhou, Z.-H., Xu, G., Zhang, W., Zhao, H., & Wu, Y. (2014) · Archives of Pathology & Laboratory Medicine · doi:10.5858/arpa.2012-0669-oa · Cited by 38 · see citing works
Microscopic Venous Invasion in Pancreatic Cancer
Yamada, M., Sugiura, T., Okamura, Y., Ito, T., Yamamoto, Y., Ashida, R., Sasaki, K., Nagino, M., & Uesaka, K. (2018) · Annals of Surgical Oncology · doi:10.1245/s10434-017-6324-2 · Cited by 37 · see citing works
Bhoo-Pathy, N. T., Inaida, S., Tanaka, S., Taib, N. A. M., Yip, C. H., Saad, M. B., Kawakami, K., & Bhoo-Pathy, N. (2017) · Cancer Epidemiology · doi:10.1016/j.canep.2017.03.007 · Cited by 36 · see citing works
Correlation Factors Analysis of Breast Cancer Tumor Volume Doubling Time Measured by 3D-Ultrasound
Zhang, S., Ding, Y., Zhou, Q., Wang, C., Peng-xi, W., & Dong, J. (2017) · Medical Science Monitor · doi:10.12659/msm.901566 · Cited by 36 · see citing works
Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma
Röder, C., Trauzold, A., & Kalthoff, H. (2010) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2010.10.008 · Cited by 35 · see citing works
Kim, H., Park, C. Y., Lee, J. H., Kim, J. C., Cho, C.-K., & Kim, H. J. (2015) · Annals of Surgical Treatment and Research · doi:10.4174/astr.2015.88.4.200 · Cited by 35 · see citing works
Childs, E. J., Rabe, K. G., Gallinger, S., Syngal, S., Schwartz, A. G., Coté, M. L., Bondy, M. L., Hruban, R. H., Chanock, S. J., Hoover, R. N., et al. (2016) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-15-1217 · Cited by 34 · see citing works
Self-citationHerman, J. M., Jabbour, S. K., Lin, S. H., Deek, M. P., Hsu, C. C.-C., Fishman, E. K., Kim, S., Cameron, J. L., Chekmareva, M. A., Laheru, D. A., et al. (2018) · Pancreas · doi:10.1097/mpa.0000000000000985 · Cited by 34 · see citing works
Self-citationPeritumoural vascular invasion: A major determinant of triple-negative breast cancer outcome
Sabatier, R., Jacquemier, J. D., Bertucci, F., Esterni, B., Finetti, P., Azario, F., Birnbaum, D., Viens, P., Gonçalvès, A., & Extra, J.-M. (2011) · European Journal of Cancer · doi:10.1016/j.ejca.2011.02.002 · Cited by 33 · see citing works
Striefler, J. K., Sinn, M., Pelzer, U., Jühling, A., Wisłocka, L., Bahra, M., Sinn, B. V., Denkert, C., Dörken, B., Oettle, H., et al. (2016) · Pathology - Research and Practice · doi:10.1016/j.prp.2016.06.001 · Cited by 32 · see citing works
Gausman, V., Kandel, P., van Riet, P. A., Moris, M., Kayal, M., Do, C., Poneros, J. M., Sethi, A., Gress, F. G., Schrope, B., et al. (2018) · Pancreas · doi:10.1097/mpa.0000000000001027 · Cited by 32 · see citing works
Jung, K. W., Kim, M.-H., Lee, T. Y., Kwon, S., Oh, H., Lee, S. S., Seo, D. W., & Lee, S. K. (2007) · Journal of Korean Medical Science · doi:10.3346/jkms.2007.22.s.s79 · Cited by 32 · see citing works
Temraz, S. N., Shamseddine, A. I., Mukherji, D., Charafeddine, M., Tfayli, A., Assi, H. I., Hammoud, M. S., Makki, I., & Nassif, S. (2018) · Pathology & Oncology Research · doi:10.1007/s12253-018-0464-y · Cited by 32 · see citing works
Time to Progression of Pancreatic Cancer: Evaluation with Multi-Detector Computed Tomography
Ahn, S. J., Choi, S. J., & Kim, H. S. (2017) · Journal of Gastrointestinal Cancer · doi:10.1007/s12029-016-9876-7 · Cited by 32 · see citing works
XPC inhibits NSCLC cell proliferation and migration by enhancing E-Cadherin expression
Cui, T., Srivastava, A. K., Han, C., Yang, L., Zhao, R., Zou, N., Qu, M., Duan, W., Zhang, X., & Wang, Q. (2015) · Oncotarget · doi:10.18632/oncotarget.3542 · Cited by 31 · see citing works
Lebe, B., Sağol, Ö., Ulukuş, Ç., Çöker, A., Karademır, S., Astarcιoglu, H., Küpelioğlu, A., Astarcιoǧlu, I., & Obuz, F. (2004) · Pathology - Research and Practice · doi:10.1016/j.prp.2004.02.010 · Cited by 31 · see citing works
Jang, K. M., Kim, S. H., Kim, Y. K., Song, K. D., Lee, S. J., & Choi, D. (2015) · European Journal of Radiology · doi:10.1016/j.ejrad.2015.05.012 · Cited by 31 · see citing works
Human Correlates of Provocative Questions in Pancreatic Pathology
McDonald, O. G., Maitra, A., & Hruban, R. H. (2012) · Advances in Anatomic Pathology · doi:10.1097/pap.0b013e318273f998 · Cited by 30 · see citing works
Self-citationFujii, T., Yajima, R., Hirakata, T., Miyamoto, T. K., Fujisawa, T., Tsutsumi, S., Ynagita, Y., Iijima, M., & Kuwano, H. (2014) · PubMed · Cited by 29 · see citing works
Bellis, D., Marci, V., & Monga, G. (1993) · Pathology - Research and Practice · doi:10.1016/s0344-0338(11)80333-x · Cited by 27 · see citing works
Venous Invasion in Colorectal Cancer: Impact of Morphologic Findings on Detection Rate
Hwang, C., Lee, S., Kim, A., Kim, Y.-G., Ahn, S., & Park, D. Y. (2016) · Cancer Research and Treatment · doi:10.4143/crt.2015.429 · Cited by 27 · see citing works
Jang, N., Choi, J. E., Kang, S. H., & Bae, Y. K. (2018) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-018-2495-x · Cited by 26 · see citing works
Histological grading of breast cancer; significance of grade on recurrence and mortality.
Ds, H., Thorogood, J., Clayden, A., & MacKinnon, D. (1989) · PubMed · Cited by 26 · see citing works
Stroma — A Double-Edged Sword in Pancreatic Cancer
Gu, J., Saiyin, H., Fu, D., & Li, J. (2018) · Pancreas · doi:10.1097/mpa.0000000000001023 · Cited by 24 · see citing works
Reflections on depletion of tumor stroma in pancreatic cancer
Wang, W.-Q., Liu, L., Xu, J.-Z., & Yu, X. (2019) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2019.01.007 · Cited by 24 · see citing works
Klingen, T. A., Chen, Y., Stefansson, I. M., Knutsvik, G., Collett, K., Abrahamsen, A. L., Aase, H. S., Aas, H., Aas, T., Wik, E., et al. (2016) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2016-203861 · Cited by 24 · see citing works
Takeshita, A., Kimura, W., Hirai, I., Takasu, N., Moriya, T., Tezuka, K., & Watanabe, T. (2011) · Pancreas · doi:10.1097/mpa.0b013e318220c1fa · Cited by 23 · see citing works
Hwang, K., Kim, J.-J., Kim, J., Chu, A. J., Chang, J. H., Oh, S. W., Hwang, K. R., & Chai, Y. J. (2017) · Breast Cancer Research and Treatment · doi:10.1007/s10549-017-4153-4 · Cited by 22 · see citing works
Sh, W., Yf, S., Liu, Y., Zhou, Y., & Liu, Y. (2015) · PubMed Central · Cited by 22 · see citing works
Preoperative estimation of neural invasion in rectal carcinoma.
Matsushima, T., Mori, M., Kido, A., Adachi, Y., & Sugimachi, K. (1998) · Oncology Reports · doi:10.3892/or.5.1.73 · Cited by 19 · see citing works
Intra‐pancreatic, Extra‐tumoral Perineural Invasion (nex)
Takahashi, T., Ishikura, H., Kato, H., Tanabe, T., & Yoshiki, T. (1992) · Acta Pathologica Japonica · doi:10.1111/j.1440-1827.1992.tb03082.x · Cited by 19 · see citing works
The clinical significance of venous invasion in cancer of the stomach
INADA, K., Shimokawa, K., Ikeda, T., & Ozeki, Y. (1990) · Surgery Today · doi:10.1007/bf02471011 · Cited by 17 · see citing works
Emerging Evidence for the Clinical Relevance of Pancreatic Cancer Exosomes
Massoumi, R. L., Hines, O. J., Eibl, G., & King, J. C. (2018) · Pancreas · doi:10.1097/mpa.0000000000001203 · Cited by 16 · see citing works
Hamada, Y., & Nakayama, Y. (2017) · Pancreatology · doi:10.1016/j.pan.2017.08.006 · Cited by 13 · see citing works
Munzone, E., Bagnardi, V., Rotmensz, N., Sporchia, A., Mazza, M., Pruneri, G., Intra, M., Sciandivasci, A., Gentilini, O., Luini, A., et al. (2014) · Breast Cancer Research and Treatment · doi:10.1007/s10549-014-3043-2 · Cited by 12 · see citing works
Therapeutic Targeting of Apoptotic Pathways: Novel Aspects in Pancreatic Cancer
Neeße, A., Gress, T. M., & Michl, P. (2012) · Current Pharmaceutical Biotechnology · doi:10.2174/138920112802501953 · Cited by 12 · see citing works
Growth process of small pancreatic carcinoma: A case report with imaging observation for 22 months
Hisa, T., Ohkubo, H., Shiozawa, S., Ishigame, H., Takamatsu, M., Furutake, M., Nobukawa, B., & Suda, K. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.1958 · Cited by 9 · see citing works
Chu, Z., Lin, H., Liang, X., Huang, R., Tang, J., Bao, Y., Jiang, J., Zhan, Q., & Zhou, X. (2015) · Japanese Journal of Clinical Oncology · doi:10.1093/jjco/hyv052 · Cited by 9 · see citing works
Zhao, X., Wei, J., Li, X., Yang, H., Wang, P., & Cao, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0193784 · Cited by 8 · see citing works
Introduction: Pancreatic Adenocarcinoma
Tempero, M. A. (2017) · The Cancer Journal · doi:10.1097/ppo.0000000000000295 · Cited by 3 · see citing works
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Goggins, M., Overbeek, K. A., Brand, R., Syngal, S., Del Chiaro, M., Bartsch, D. K., Bassi, C., Carrato, A., Farrell, J., Fishman, E. K., et al. (2020) · Gut · doi:10.1136/gutjnl-2019-319352 · Cited by 659 · see citing works
Self-citationProteogenomic characterization of pancreatic ductal adenocarcinoma
Cao, L., Huang, C., Cui Zhou, D., Hu, Y., Lih, T. M., Savage, S. R., Krug, K., Clark, D. J., Schnaubelt, M., Chen, L., et al. (2021) · Cell · doi:10.1016/j.cell.2021.08.023 · Cited by 578 · see citing works
Self-citationCODA: quantitative 3D reconstruction of large tissues at cellular resolution
Kiemen, A. L., Braxton, A. M., Grahn, M. P., Han, K. S., Babu, J. M., Reichel, R., Jiang, A. C., Kim, B., Hsu, J., Amoa, F., et al. (2022) · Nature Methods · doi:10.1038/s41592-022-01650-9 · Cited by 218 · see citing works
Self-citationArtificial intelligence in pancreatic cancer
Huang, B., Huang, H., Zhang, S., Zhang, D., Shi, Q., Liu, J., & Guo, J. (2022) · Theranostics · doi:10.7150/thno.77949 · Cited by 142 · see citing works
“However, classical prognostic factors, such as lymph node status and American Joint Committee on Cancer (AJCC) stage, are not entirely relevant in some long-term survivors [201,202].”
BackgroundThe Evolutionary Origins of Recurrent Pancreatic Cancer
Sakamoto, H., Attiyeh, M. A., Gerold, J. M., Makohon-Moore, A. P., Hayashi, A., Hong, J., Kappagantula, R. L., Zhang, L., Melchor, J. P., Reiter, J. G., et al. (2020) · Cancer Discovery · doi:10.1158/2159-8290.cd-19-1508 · Cited by 118 · see citing works
Self-citationMasugi, Y., Abe, T., Ueno, A., Fujii‐Nishimura, Y., Ojima, H., Endo, Y., Fujita, Y., Kitago, M., Shinoda, M., Kitagawa, Y., et al. (2019) · Modern Pathology · doi:10.1038/s41379-019-0291-z · Cited by 113 · see citing works
Clinical applications of mass spectrometry‐based proteomics in cancer: Where are we?
Boys, E. L., Liu, J., Robinson, P. J., & Reddel, R. R. (2022) · PROTEOMICS · doi:10.1002/pmic.202200238 · Cited by 65 · see citing works
Hong, S., JUNG, D., Kiemen, A. L., Gaida, M. M., Yoshizawa, T., Braxton, A. M., Noë, M., Lionheart, G., Oshima, K., Thompson, E. D., et al. (2019) · Modern Pathology · doi:10.1038/s41379-019-0409-3 · Cited by 62 · see citing works
Self-citationLINC00941 promotes glycolysis in pancreatic cancer by modulating the Hippo pathway
Xu, M., Cui, R., Ye, L., Wang, Y., Wang, X., Zhang, Q., Wang, K., Dong, C., Le, W., & Chen, B. (2021) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2021.07.004 · Cited by 51 · see citing works
Šermukšnytė, A., Kantminienė, K., Jonuškienė, I., Tumosienė, I., & Petrikaitė, V. (2022) · Pharmaceuticals · doi:10.3390/ph15081026 · Cited by 45 · see citing works
Lin, J., Yin, M., Liu, L., Gao, J., Yu, C., Liu, X., Xu, C., & Zhu, J. (2022) · Cancers · doi:10.3390/cancers14194667 · Cited by 45 · see citing works
Kiemen, A. L., Damanakis, A. I., Braxton, A. M., He, J. P., Laheru, D. A., Fishman, E. K., Chames, P., Almagro-Pérez, C., Wu, P., Wirtz, D., et al. (2023) · Med · doi:10.1016/j.medj.2022.11.009 · Cited by 42 · see citing works
Self-citationA primer on artificial intelligence in pancreatic imaging
Ahmed, T. M., Kawamoto, S., Hruban, R. H., Fishman, E. K., Soyer, P. A., & Chu, L. C. H. (2023) · Diagnostic and Interventional Imaging · doi:10.1016/j.diii.2023.03.002 · Cited by 43 · see citing works
Self-citationThompson, E. D., Roberts, N. J., Wood, L. D., Eshleman, J. R., Goggins, M., Kern, S. E., Klein, A. P., & Hruban, R. H. (2020) · Modern Pathology · doi:10.1038/s41379-020-0629-6 · Cited by 39 · see citing works
Self-citationEnzyme therapy: a forerunner in catalyzing a healthy society?
Datta, S., Rajnish, K. N., Doss, C. G. P., Samuel, S. M., Ethiraj, S., & Zayed, H. (2020) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2020.1787980 · Cited by 38 · see citing works
Copy Number Variations in Pancreatic Cancer: From Biological Significance to Clinical Utility
Oketch, D. J. A., Giulietti, M., & Piva, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010391 · Cited by 36 · see citing works
Pancreatic Cancer Imaging: A New Look at an Old Problem
Chu, L. C. H., Park, S., Kawamoto, S., Yuille, A., Hruban, R. H., & Fishman, E. K. (2020) · Current Problems in Diagnostic Radiology · doi:10.1067/j.cpradiol.2020.08.002 · Cited by 31 · see citing works
Self-citationYan, J., Wu, L., Jia, C., Yu, S., Lu, Z., Sun, Y., & Chen, J. (2020) · Aging · doi:10.18632/aging.102844 · Cited by 29 · see citing works
Mentis, A. A., Grivas, P. D., Dardiotis, E., Romas, N. A., & Papavassiliou, A. G. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03529-4 · Cited by 29 · see citing works
Zhao, B., Xia, C., Xia, T., Qiu, Y., Zhu, L., Cao, B., Gao, Y., Ge, R., Cai, W., Ding, Z., et al. (2023) · International Journal of Surgery · doi:10.1097/js9.0000000000000908 · Cited by 29 · see citing works
Ji, T., Ma, K., Wu, H., & Cao, T. (2022) · Journal of Immunology Research · doi:10.1155/2022/5582811 · Cited by 27 · see citing works
Mayer, P., Jiang, Y., Kuder, T. A., Bergmann, F., Khristenko, E., Steinle, V., Kaiser, J., Hackert, T., Kauczor, H., Klauß, M., et al. (2020) · Cancers · doi:10.3390/cancers12061656 · Cited by 26 · see citing works
Self-citationProteomics-Driven Biomarkers in Pancreatic Cancer
Ramalhete, L., Vigia, E., Araújo, R., & Marques, H. P. (2023) · Proteomes · doi:10.3390/proteomes11030024 · Cited by 24 · see citing works
Pu, N., Gao, S., Beckman, R. M., Ding, D., Wright, M. J., Chen, Z., Zhu, Y., Hu, H., Yin, L., Beckman, M. J., et al. (2020) · HPB · doi:10.1016/j.hpb.2020.08.016 · Cited by 24 · see citing works
Self-citationConte, M., & Cauda, V. (2022) · Advanced Therapeutics · doi:10.1002/adtp.202200079 · Cited by 26 · see citing works
Comparative molecular profiling of pancreatic ductal adenocarcinoma of the head versus body and tail
Abdelrahim, M., Esmail, A., Kasi, A., Esnaola, N. F., Xiu, J., Baca, Y., & Weinberg, B. A. (2024) · npj Precision Oncology · doi:10.1038/s41698-024-00571-4 · Cited by 22 · see citing works
Novak, S., Kolář, M., Szabó, Á., Vernerová, Z., Lacina, L., Strnad, H., Šáchová, J., Hradilová, M., Havránek, J., Španko, M., et al. (2021) · Cancer Genomics & Proteomics · doi:10.21873/cgp.20254 · Cited by 20 · see citing works
Schreyer, D., Neoptolemos, J. P., Barry, S. T., & Bailey, P. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.795735 · Cited by 19 · see citing works
Novel systemic treatment approaches for metastatic pancreatic cancer
Dorman, K., Heinemann, V., Kobold, S., von Bergwelt‐Baildon, M., & Boeck, S. H. (2022) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2022.2037552 · Cited by 19 · see citing works
Fujita, Y., Matsuda, S., Sasaki, Y., Masugi, Y., Kitago, M., Yagi, H., Abe, Y., Shinoda, M., Tokino, T., Sakamoto, M., et al. (2019) · Cancer Science · doi:10.1111/cas.14268 · Cited by 17 · see citing works
Søreide, K., Roalsø, M. T. T., & Aunan, J. R. (2020) · Journal of Pancreatic Cancer · doi:10.1089/pancan.2019.0014 · Cited by 17 · see citing works
Treatment optimization of locally advanced and metastatic pancreatic cancer (Review)
Barros, A., Pulido, C., Machado, M., Brito, M. J., Couto, N., Sousa, O., Melo, S. A., & Mansinho, H. (2021) · International Journal of Oncology · doi:10.3892/ijo.2021.5290 · Cited by 17 · see citing works
Pinkert‐Leetsch, D., Frohn, J., Ströbel, P., Alves, F., Salditt, T., & Missbach‐Guentner, J. (2023) · Cancer Imaging · doi:10.1186/s40644-023-00559-6 · Cited by 16 · see citing works
Desmin and CD31 immunolabeling for detecting venous invasion of the pancreatobiliary tract cancers
Shin, J., Wood, L. D., Hruban, R. H., & Hong, S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0242571 · Cited by 16 · see citing works
Self-citationShui, L., Li, X., Peng, Y., Tian, J., Li, S., He, D., Li, A., Tian, B., Mao, L., Gao, H., et al. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-02972-6 · Cited by 16 · see citing works
The role of molecular testing in pancreatic cancer
Zhen, D. B., Safyan, R. A., Konick, E. Q., Nguyen, R., Pritchard, C. C., & Chiorean, E. G. (2023) · Therapeutic Advances in Gastroenterology · doi:10.1177/17562848231171456 · Cited by 15 · see citing works
Cell Dissemination in Pancreatic Cancer
Kim, J. (2022) · Cells · doi:10.3390/cells11223683 · Cited by 17 · see citing works
Evaluation and prognostic significance of tumor budding in pancreatic ductal adenocarcinomas
Argon, A., Öz, Ö., & Kebat, T. A. (2023) · Indian Journal of Pathology and Microbiology · doi:10.4103/ijpm.ijpm_905_21 · Cited by 14 · see citing works
Accurate Nodal Staging in Pancreatic Cancer in the Era of Neoadjuvant Therapy
Javed, A. A., Ding, D., Baig, E., Wright, M. J., Teinor, J. A., Ali, D. M., Thompson, E. D., Hruban, R. H., Narang, A. K., Burns, W. R., et al. (2022) · World Journal of Surgery · doi:10.1007/s00268-021-06410-y · Cited by 14 · see citing works
Self-citationKong, R., Qian, X., & Ying, W. (2022) · Scientific Data · doi:10.1038/s41597-022-01407-1 · Cited by 13 · see citing works
Lee, S. J., Sung, Y.-N., Kim, S. J., Shin, S., Cho, H., Hruban, R. H., & Hong, S. (2020) · Pancreatology · doi:10.1016/j.pan.2020.08.015 · Cited by 13 · see citing works
Self-citationExperimental models of pancreas cancer: what has been the impact for precision medicine?
Pantazopoulou, V., Kubota, C. S., Ogawa, S., Gulay, K. C. M., Lin, X., Song, H., Weitz, J., Tiriac, H., Lowy, A. M., & Engle, D. D. (2025) · Journal of Clinical Investigation · doi:10.1172/jci191945 · Cited by 13 · see citing works
Heterocellular crosstalk and architecture of the pancreatic tumour microenvironment
Arnold, F., Vecchio, A. D., Hussain, Z., & Sherman, M. H. (2026) · Nature reviews. Cancer · doi:10.1038/s41568-025-00905-9 · Cited by 14 · see citing works
Chen, X., Chen, L., Miao, J., Huang, X., Han, X., Zheng, L., Xu, S., Chen, J., & Li, L. (2024) · BMC Cancer · doi:10.1186/s12885-024-12412-5 · Cited by 12 · see citing works
Pelizzaro‐Rocha, K. J., Fonseca, E. M. B., Oliveira, B. G. D. F., de Fátima, Â., & Ferreira‐Halder, C. V. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.103881 · Cited by 12 · see citing works
Carrillo‐Pérez, F., Ortuño, F. M., Börjesson, A., Rojas, I., & Herrera, L. J. (2023) · Cancer Imaging · doi:10.1186/s40644-023-00586-3 · Cited by 10 · see citing works
Habib, J. R., Rompen, I. F., Kaslow, S. R., Grewal, M., Andel, P. C. M., Zhang, S., Hewitt, D. B., Cohen, S. M., van Santvoort, H. C., Besselink, M. G., et al. (2024) · Annals of Surgery · doi:10.1097/sla.0000000000006295 · Cited by 11 · see citing works
Screening for Pancreatic Cancer Gets a D, but the Student Is Improving
Hruban, R. H., & Lillemoe, K. D. (2019) · JAMA Surgery · doi:10.1001/jamasurg.2019.2832 · Cited by 11 · see citing works
Self-citationKim, S. J., Choi, S. J., Yang, J., Kim, D., Kim, D. W., Byun, J. H., & Hong, S. (2022) · Human Pathology · doi:10.1016/j.humpath.2022.05.018 · Cited by 9 · see citing works
Self-citationNeoantigens and their clinical applications in human gastrointestinal cancers
Eshkiki, Z. S., Agah, S., Tabaeian, S. P., Sedaghat, M., Dana, F., Talebi, A., & Akbari, A. (2022) · World Journal of Surgical Oncology · doi:10.1186/s12957-022-02776-y · Cited by 10 · see citing works
Nævdal, G., Rofstad, E. K., Søreide, K., & Steinar Evje, A. (2022) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2022.111362 · Cited by 10 · see citing works
Pankreaskarzinom – Chirurgie im Wandel der multimodalen Therapiemöglichkeiten
Belyaev, O., & Uhl, W. H. (2019) · Allgemein- und Viszeralchirurgie up2date · doi:10.1055/a-1034-3032 · Cited by 9 · see citing works
Park, S., Kim, J. H., Joo, I., Lee, K. B., & Han, J. K. (2020) · European Radiology · doi:10.1007/s00330-020-07489-y · Cited by 9 · see citing works
Hu, H., Chen, W., Zhang, S., Xue, Y., He, Y., & Gu, Y. (2021) · Journal of Cancer · doi:10.7150/jca.58824 · Cited by 9 · see citing works
Predicting Gemcitabine Delivery by18F-FAC PET in Murine Models of Pancreatic Cancer
Russell, J., Grkovski, M., O’Donoghue, I., Kalidindi, T. M., Pillarsetty, N., Burnazi, E. M., Kulick, A. R., Bahr, A., Chang, Q., Lekaye, C., et al. (2020) · Journal of Nuclear Medicine · doi:10.2967/jnumed.120.246926 · Cited by 9 · see citing works
Wu, F., Tabang, D. N., Wang, D., Odorico, J. S., & Li, L. (2025) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2025.100969 · Cited by 8 · see citing works
Shang, X. C., Shi, L., Taule, D., & Zhu, Z.-Z. (2021) · Cancer Management and Research · doi:10.2147/cmar.s316935 · Cited by 8 · see citing works
Recent developments of nanomedicine delivery systems for the treatment of pancreatic cancer
Rezaei, N., Shahriari, M., & Mehrnejad, F. (2022) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2022.104042 · Cited by 8 · see citing works
Alfonzetti, T., Moreau, M., Yasmin‐Karim, S., Ngwa, W. F., Avery, S., & Goia, D. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2022.1085686 · Cited by 8 · see citing works
Gits, H. C., Tang, A., Harmsen, W. S., Bamlet, W. R., Graham, R. P., Petersen, G. M., Smyrk, T. C., Mahipal, A., Kowalchuk, R. O., Ashman, J. B., et al. (2021) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo-21-55 · Cited by 8 · see citing works
Wakiya, T., Ishido, K., Kimura, N., Nagase, H., Yoshizawa, T., Morohashi, S., Fujita, H., Kanda, T., Tatara, Y., Saruwatari, J., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-00727-3 · Cited by 7 · see citing works
Ovarian Metastasis from Pancreatic Ductal Adenocarcinoma
Habib, J. R., Pasha, S., Khan, S., Kinny‐Köster, B., Shoucair, S., Thompson, E. D., Yu, J., Lafaro, K. J., Burkhart, R. A., Burns, W. R., et al. (2021) · World Journal of Surgery · doi:10.1007/s00268-021-06209-x · Cited by 6 · see citing works
Self-citationDo arterial resections improve survival in pancreatic cancer?—a narrative review
Rebelo, A., Ronellenfitsch, U., Döbereiner, J., Ukkat, J., & Kleeff, J. H. (2021) · Chinese Clinical Oncology · doi:10.21037/cco-21-39 · Cited by 6 · see citing works
Sung, Y. (2025) · American Journal of Cancer Research · doi:10.62347/ovuj4436 · Cited by 5 · see citing works
Mokhtari, A., Casale, R., Salahuddin, Z., Paquier, Z., Guiot, T., Woodruff, H. C., Lambin, P., Laethem, J. V., Hendlisz, A., & Bali, M. A. (2024) · Diagnostics · doi:10.3390/diagnostics14070712 · Cited by 5 · see citing works
Javed, A. A., Habib, J. R., Kinny‐Köster, B., Hodgin, M. B., Parish, L., Cunningham, D., Hacker‐Prietz, A., Burkhart, R. A., Burns, W. R., Shubert, C. R., et al. (2022) · Current Problems in Diagnostic Radiology · doi:10.1067/j.cpradiol.2022.05.001 · Cited by 5 · see citing works
Self-citationStorkholm, J. H., Burgdorf, S. K., Larsen, P. N., & Hansen, C. P. (2023) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-023-03054-5 · Cited by 4 · see citing works
Stefanoudakis, D. (2025) · SynBio · doi:10.3390/synbio3010001 · Cited by 5 · see citing works
Pankreaskarzinom – Pathologie, Ätiologie und diagnostisches Vorgehen
Belyaev, O., & Uhl, W. H. (2019) · Allgemein- und Viszeralchirurgie up2date · doi:10.1055/a-0953-2938 · Cited by 4 · see citing works
Li, Q. K., Hu, Y., Chen, L., Schnaubelt, M., Zhou, D. C., Li, Y., Lu, R. J.-H., Thiagarajan, M., Hostetter, G. H., Newton, C. J., et al. (2022) · Clinical Proteomics · doi:10.1186/s12014-022-09373-x · Cited by 4 · see citing works
Self-citationDie ambivalente Rolle des Tumormikromilieus bei soliden Tumoren
Gaida, M. M. (2020) · Der Pathologe · doi:10.1007/s00292-020-00837-1 · Cited by 4 · see citing works
Self-citationZignani, N., Balzarini, M., Dabizzi, E., Fracas, E., Millefanti, L., Segato, S., Vecchi, M., Cengia, G., Missale, G., Tontini, G. E., et al. (2025) · World Journal of Gastrointestinal Endoscopy · doi:10.4253/wjge.v17.i11.112487 · Cited by 3 · see citing works
Lopez, A., Zobolas, J., Lingjærde, O. C., Nebdal, D. J. H., Fleischer, T., & Aittokallio, T. A. (2024) · Nordic Machine Intelligence · doi:10.5617/nmi.10584 · Cited by 3 · see citing works
Li, H., Pan, W., Xu, L., Yin, D., Cheng, S., & Zhao, F. (2021) · Medical Science Monitor · doi:10.12659/msm.930545 · Cited by 3 · see citing works
Clinical Relevance of Cancerization of Ducts in Resected Pancreatic Ductal Adenocarcinoma
Kinny‐Köster, B., Ahmad, Y., Pflüger, M. J., Habib, J. R., Fujikura, K., Hutchings, D., Cameron, J. L., Shubert, C. R., Lafaro, K. J., Burkhart, R. A., et al. (2024) · Pancreas · doi:10.1097/mpa.0000000000002326 · Cited by 3 · see citing works
Self-citationNeoplasms of the Exocrine Pancreas
Wolff, R. A., Li, D., Maitra, A., Tsai, S., Koay, E. J., & Evans, D. B. (2022) · Holland‐Frei Cancer Medicine · doi:10.1002/9781119000822.hfcm094.pub2 · Cited by 3 · see citing works
Rezagholizadeh, F., Salimi, A., Sharifi‐Zarchi, A., Azmoudeh-Ardalan, F., Mousavizadeh, K., Tajik, F., Panahi, M., Khorramdelazad, H., Wadji, M. B., Kashanizadeh, A., et al. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03810-1 · Cited by 2 · see citing works
Mayer, P., Kraft, A., Roth, W., Hackert, T., Bergmann, F., Kauczor, H., Steinle, V., Khristenko, E., Klauß, M., & Gaida, M. M. (2021) · Journal of Cancer · doi:10.7150/jca.63633 · Cited by 2 · see citing works
Self-citationMayer, P., Hausen, A., Steinle, V., Bergmann, F., Kauczor, H., Loos, M., Roth, W., Klauß, M., & Gaida, M. M. (2024) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-024-03355-3 · Cited by 2 · see citing works
Self-citationSaleh, K. K., Kırbağ, S., & Dalkılıç, S. (2022) · International journal of medicinal mushrooms · doi:10.1615/intjmedmushrooms.2022044383 · Cited by 2 · see citing works
Liu, B., Wu, J., Li, C., Li, Y., Qiu, H., Lv, A., Liu, Q., Liu, D.-N., Wang, Z., & Hao, C. (2021) · Pancreatology · doi:10.1016/j.pan.2021.11.001 · Cited by 2 · see citing works
Circulating Fatty Objects and Their Preferential Presence in Pancreatic Cancer Patient Blood Samples
Wang, R., Nissen, N. N., Zhang, Y., Shao, C., Chu, C.-Y., Huynh, C. A., Posadas, E. M., Tomlinson, J. S., Lewis, M. S., & Pandol, S. J. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.827531 · Cited by 2 · see citing works
Machine learning identifies 6-gene signature in peripheral blood for pancreatic cancer diagnosis
Carrillo‐Pérez, F., Caba, O., Jiménez‐Luna, C., Ortuño, F. M., Castillo-Secilla, D., Herrera, L. J., Prados, J. C., & Rojas, I. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e43138 · Cited by 2 · see citing works
Half the Chromosome It Used to Be: Identifying Cancer Treatments Targeting Aneuploid Losses
Disharoon, A., & Delaney, J. R. (2025) · Genes · doi:10.3390/genes16060708 · Cited by 1 · see citing works
Core-fucosylated glycoproteins as biomarkers for diagnosing pancreatic ductal adenocarcinoma
Zhao, X., Huang, Y., Wu, J., Wang, A., Yang, G., Hao, C., & Ying, W. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.146774 · Cited by 1 · see citing works
Modeling tumor dynamics and predicting response to therapies in a murine pancreatic cancer model
Vishwanath, K., Choi, H., Gupta, M., Zhou, R., Sorace, A. G., Yankeelov, T. E., & Lima, E. A. B. F. (2025) · npj Systems Biology and Applications · doi:10.1038/s41540-025-00593-z · Cited by 1 · see citing works
Jung, K., Lee, J.-C., Kim, J.-H., Na, H. Y., Kim, J. H., Youn, Y., Para, N., Kim, J., & Hwang, J. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.218176 · Cited by 1 · see citing works
Fang, T., Liu, D., Chen, X., Zhou, K., Hao, C., & Yue, S. (2026) · Medical Image Analysis · doi:10.1016/j.media.2026.104181 · Cited by 1 · see citing works
Recent Advancements for the Management of Pancreatic Cancer: Current Insights
Ali, N., & Srivastava, N. (2021) · Current Cancer Therapy Reviews · doi:10.2174/1573394717666210625153256 · Cited by 1 · see citing works
Cardamonin Induces Apoptosis and Suppresses the Proliferation of BxPC3 Cells
Xu, X. W., Zheng, J. J., Gao, D. S., & Hu, Q. (2022) · Indian Journal of Pharmaceutical Sciences · doi:10.36468/pharmaceutical-sciences.spl.413 · Cited by 1 · see citing works
Metastatic pancreatic cancer with activating BRAF V600E mutations: A case report
Li, F., & Shen, F. (2025) · World Journal of Clinical Cases · doi:10.12998/wjcc.v13.i16.101665 · Cited by 1 · see citing works
Accuracy of Lymph Node Staging in Pancreatic Cancer after Neoadjuvant Therapy
Zaharia, C., & Søreide, K. (2022) · World Journal of Surgery · doi:10.1007/s00268-021-06431-7 · Cited by 1 · see citing works
SP/NK-1R Axis Promotes Perineural Invasion of Pancreatic Cancer and is Affected by lncRNA LOC389641Preprint
Ji, T., Ma, K., Wu, H., & Cao#, T. (2021) · Research Square · doi:10.21203/rs.3.rs-1150419/v1 · Cited by 1 · see citing works
Pancreatoduodenectomy for Pancreatic Cancer
Kinny‐Köster, B., Cameron, J. L., & He, J. P. (2023) · doi:10.1002/9781119876007.ch136 · Cited by 1 · see citing works
- Self-citation
Shui, L., Li, X., Yang, P., Tian, J., Li, S., He, D., Li, A., Tian, B., Mao, L., Yi, C., et al. (2020) · doi:10.21203/rs.3.rs-60530/v1
Pathology of Pancreatic Cancer
Hruban, R. H., & Thompson, E. D. (2022) · Springer eBooks · doi:10.1007/978-981-19-0063-1_12
Self-citationDuctal Adenocarcinoma and Pancreatic Intraepithelial Neoplasia
(2023) · American Registry of PathologyArlington, Virginia eBooks · doi:10.55418/9781933477275-07
Li, Q. K., Hu, Y., Chen, L., Schnaubelt, M., Zhou, D. C., Li, Y., Lu, R. J.-H., Thiagarajan, M., Hostetter, G. H., Newton, C. J., et al. (2022) · Figshare · doi:10.6084/m9.figshare.21376233
Self-citationVishwanath, K., Choi, H., Gupta, M., Zhou, R., Sorace, A. G., Yankeelov, T. E., & Lima, E. A. B. F. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.03.631015
- Authors
- Hruban, R. H., Gaida, M. M., Thompson, E., Hong, S., Noë, M., Brosens, L. A., Jongepier, M., Offerhaus, G. J. A., & Wood, L. D.
- Affiliations
- Johns Hopkins University (US)
- University Hospital Heidelberg (DE)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Corresponding author
- Hruban, Ralph H
- ORCID
- Venue
- The Journal of Pathology
- Publisher
- Wiley
- Published
- 2019-04-15
- Volume
- 248
- Issue
- 2
- Pages
- 131-141
- ISSN
- 0022-3417 (ISSN-L)
- 1096-9896
- OpenAlex
- W2921693296
- Cited by
- 115
- References
- 171
- Citations by year
- 2026: 11 · 2025: 17 · 2024: 7 · 2023: 14 · 2022: 24 · 2021: 18 · 2020: 17 · 2019: 7
- FWCI
- 1.59
- Type
- journal article
- Language
- en
- Open access
- green
- dspace.library.uu.nl
- Licence
- Locations
- The Journal of Pathology (publishedVersion)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- Funders
- National Institutes of Health (1s10od020152-01a1)
- Topics
- Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
- Health Sciences › Medicine › Surgery › Pancreatitis Pathology and Treatment
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Keywords
- pancreatic cancer, venous invasion, tumor aggressiveness, prognosis, metastasis
- MeSH terms
- Cell Differentiation, Humans, Lymphatic Metastasis, Neoplasm Invasiveness, Neoplasm Staging, Pancreatic Neoplasms, Risk Factors, Veins, Disease Progression, Risk Assessment, Carcinoma, Pancreatic Ductal, Cell Proliferation, Epithelial-Mesenchymal Transition
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