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m6A enhances the phase separation potential of mRNA
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“With stress, m6A translocates into the cytoplasm, where it enhances liquid-liquid phase separation and associates with SGs”
From Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy (2021) · cites this paper as Ries et al., 2019
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STAR: ultrafast universal RNA-seq aligner
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N6-methyladenosine-dependent regulation of messenger RNA stability
Wang, X., Lu, Z., Gomez, A., Hon, G. C., Yue, Y., Han, D., Fu, Y., Parisien, M., Dai, Q., Jia, G., et al. (2014) · Nature · doi:10.1038/nature12730 · Cited by 4,558
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
Meyer, K. D., Saletore, Y., Zumbo, P., Elemento, O., Mason, C. E., & Jaffrey, S. R. (2012) · Cell · doi:10.1016/j.cell.2012.05.003 · Cited by 4,223
Self-citationm6A RNA methylation promotes XIST-mediated transcriptional repression
Patil, D. P., Chen, C.-K., Pickering, B. F., Chow, A., Jackson, C., Guttman, M., & Jaffrey, S. R. (2016) · Nature · doi:10.1038/nature19342 · Cited by 1,747
Self-citationSingle-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
Linder, B., Grozhik, A. V., Olarerin-George, A. O., Meydan, C., Mason, C. E., & Jaffrey, S. R. (2015) · Nature Methods · doi:10.1038/nmeth.3453 · Cited by 1,569
Self-citationA “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards
Wiśniewski, J. R., Hein, M. Y., Cox, J., & Mann, M. (2014) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m113.037309 · Cited by 690
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Cited by
Reading, writing and erasing mRNA methylation
Zaccara, S., Ries, R. J., & Jaffrey, S. R. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0168-5 · Cited by 2,597
Self-citationThe m6A epitranscriptome: transcriptome plasticity in brain development and function
Livneh, I., Moshitch-Moshkovitz, S., Amariglio, N., Rechavi, G., & Dominissini, D. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0244-z · Cited by 330
RNA m6A regulates transcription via DNA demethylation and chromatin accessibility
Deng, S., Zhang, J., Su, J., Zuo, Z., Zeng, L., Liu, K., Zheng, Y., Huang, X., Bai, R., Zhuang, L., et al. (2022) · Nature Genetics · doi:10.1038/s41588-022-01173-1 · Cited by 187
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
Jiang, L., Lin, W., Zhang, C., Ash, P. E. A., Verma, M., Kwan, J., van Vliet, E., Yang, Z., Cruz, A. L., Boudeau, S., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.07.038 · Cited by 177
Chromatin basis of the senescence-associated secretory phenotype
Hao, X., Wang, C., & Zhang, R. (2022) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.12.003 · Cited by 94
Metadata
- Authors
- Ries, R. J., Zaccara, S., Klein, P., Olarerin-George, A., Namkoong, S., Pickering, B. F., Patil, D. P., Kwak, H., Lee, J. H., & Jaffrey, S. R.
- Venue
- Nature
- Published
- 2019-07-10
- Volume
- 571
- Issue
- 7765
- Pages
- 424-428
- ISSN
- 0028-0836
- 1476-4687
- PMC
- PMC6662915
- Cited by
- 714
- References
- 6
- Language
- en
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- Ries, R. J., Zaccara, S., Klein, P., Olarerin-George, A., Namkoong, S., Pickering, B. F., Patil, D. P., Kwak, H., Lee, J. H., & Jaffrey, S. R. (2019). m6A enhances the phase separation potential of mRNA. Nature. https://doi.org/10.1038/s41586-019-1374-1
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