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Immunization: vital progress, unfinished agenda
Open accessAbstract
Vaccination against infectious diseases has changed the future of the human species, saving millions of lives every year, both children and adults, and providing major benefits to society as a whole. Here we show, however, that national and sub-national coverage of vaccination varies greatly and major unmet needs persist. Although scientific progress opens exciting perspectives in terms of new vaccines, the pathway from discovery to sustainable implementation can be long and difficult, from the financing, development and licensing to programme implementation and public acceptance. Immunization is one of the best investments in health and should remain a priority for research, industry, public health and society.
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“Immune memory is the source of protective immunity from a subsequent infection (Orenstein and Ahmed, 2017; Piot et al., 2019; Plotkin et al., 2018).”
From Adaptive immunity to SARS-CoV-2 and COVID-19 (2021) · cites this paper as Piot et al., 2019
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Nadh, P. O. (2026) · Springer eBooks · doi:10.1007/978-981-95-8349-2_2
Feleke, H. G., Simegn, M. B., Worede, D. T., & Tilahun, W. M. (2026) · PLoS ONE · doi:10.1371/journal.pone.0345899
Joe, W., Kumar, S., & Pahuja, I. (2026) · Springer eBooks · doi:10.1007/978-981-95-7868-9_5
Childhood vaccination coverage and socioeconomic inequalities in the Northern region of Brazil
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Metadata
- Authors
- Piot, P., Larson, H. J., O’Brien, K. L., N’kengasong, J., Ng, E., Sow, S., & Kampmann, B.
- Affiliations
- London School of Hygiene & Tropical Medicine (GB)
- University of Antwerp (BE)
- World Health Organization (CH)
- Centre Pour le Développement des Vaccins-Mali (ML)
- Venue
- Nature
- Published
- 2019-11-06
- Volume
- 575
- Issue
- 7781
- Pages
- 119-129
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W2985393490
- Cited by
- 206
- References
- 72
- Citations by year
- 2026: 21 · 2025: 23 · 2024: 28 · 2023: 21 · 2022: 45 · 2021: 39 · 2020: 29
- FWCI
- 6.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Funders
- Bill and Melinda Gates Foundation
- Pfizer
- World Health Organization
- Wellcome Trust
- UK Research and Innovation
- National Institute for Health and Care Research (SRF-2009-02-07)
- European Commission
- Medical Research Council (MR/R005990/1, MC_PC_17221, MR/R005990/2, MC_EX_MR/K011944/1, MC_EX_MR/P024270/1)
- Topics
- Social Sciences › Health › Vaccine Coverage and Hesitancy
- Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Keywords
- immunization, vaccination, vaccination coverage, vaccine development, vaccine implementation, vaccine safety, vaccine financing, vaccine licensure, vaccine hesitancy, infectious disease prevention, public health investment
- MeSH terms
- Drug Development, Animals, Humans, Mortality, Philippines, Social Change, Vaccination, Vaccines
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